Travel Information
Compare bus, train, and flight for Osnabrück to Prague
Omio recommends booking the bus as it is the most popular option from Osnabrück to Prague among Omio's users. If you are prioritising price, take the bus, with an average ticket price of Kč 1,359 For those with little time, consider booking a flight, which has an average total journey time of 4h 59m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.2 - 0.5kg. Average ticket prices depend on the travel mode: a bus costs an average of Kč 1,359, while a flight costs an average of Kč 10,537.
Distance: 314 miles (506 km)
Compare bus with
Most popular Bus | Train | Flight | Driving |
|---|---|---|---|
Kč 1,359 Average price Cheapest | Kč 3,293 Average price | Kč 10,537 Average price | Kč 2,686 Average price (fuel + tolls) |
11h 0m Average total duration 10h 30m Onboard + 30m Additional time* | 8h 16m Average total duration 7h 46m Onboard + 30m Additional time* | 4h 59m Average total duration Fastest 2h 59m Onboard + 2h 0m Additional time* | 6h 50m Average total duration (door-to-door) |
0.5 - 1.3kg CO2 emissions | 0.2 - 0.5kg CO2 emissions Lowest | 1.5 - 3.0kg CO2 emissions | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Compare ways to travel from Osnabrück to Prague
Compare the available ways to get from Osnabrück to Prague, with the key details around price, speed, convenience, and direct service.
This is compared to other travel options from Osnabrück to Prague:
A bus is Kč 1,935 less than a train for this route with tickets for a train from Osnabrück to Prague costing on average Kč 3,293.
A bus is Kč 9,178 less than a flight for this route with tickets for a flight from Osnabrück to Prague costing on average Kč 10,537.
Other travel options to Prague take longer:
Train takes on average 8h 16m.
Bus takes on average 11h 0m.
Tickets start at around Kč 1,359 compared to roughly Kč 2,686 in fuel and tolls — a saving of about Kč 1,327. The journey takes 10h 30m versus 6h 50m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
Travel optionsfrom Osnabrück to Prague
How to get from Osnabrück to Prague by train, bus or flight.
Our recommendation
The best way to travel from Osnabrück to Prague is by taking a bus because it’s the best combination of price and speed.

6:25 AM 10h15 Osnabrück 4:40 PM Prague Kč 865 1 One-way 0 transfers
Cheapest

6:25 AM 10h15 Osnabrück 4:40 PM Prague Kč 865 1 One-way 0 transfers
Fastest

6:25 AM 10h15 Osnabrück 4:40 PM Prague Kč 865 1 One-way 0 transfers
Other options

6:55 PM 10h15 Osnabrück 5:10 AM Prague Kč 1,011 1 One-way 0 transfers
7:25 AM 10h15 Osnabrück 5:40 PM Prague Kč 1,068 1 One-way 0 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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FAQs: Travel from Osnabrück to Prague
Travel to Prague easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Osnabrück to Prague.

This is compared to other travel options from Osnabrück to Prague:
A bus is Kč 1,935 less than a train for this route with tickets for a train from Osnabrück to Prague costing on average Kč 3,293.
A bus is Kč 9,178 less than a flight for this route with tickets for a flight from Osnabrück to Prague costing on average Kč 10,537.
Other travel options to Prague take longer:
Train takes on average 8h 16m.
Bus takes on average 11h 0m.
- Around 60 flights per day.
- Around 8 trains per day.
- Around 8 buses per day.
However, we recommend checking specific travel dates for your route between Osnabrück and Prague as scheduled services by bus, train, and flight can vary by season or day of the week.
- Flights mostly depart from Dusseldorf Airport and arrive in Prague Vaclav Havel Airport.
- Trains mostly depart from Osnabrück Hbf and arrive in Prague hlavní nádraží.
- Buses mostly depart from Osnabrück, Hauptbahnhof and arrive in Prague, Central Train Station.
- Travel with FlixBus to go to Prague by bus.
- Travel with Deutsche Bahn, České dráhy, alex-Länderbahn und Vogtlandbahn-GmbH, WestfalenBahn to go to Prague by train.
- Travel with KLM, Lot Polish Airlines, Lufthansa, Turkish Airlines, Air France, Eurowings, British Airways, Lufthansa City Airlines, Swiss, Air Baltic, KLM Cityhopper, Smartwings, Lufthansa Cityline, Austrian Airlines, Air Dolomiti, Qatar Airways, Helvetic Airways, Avion Express Malta, Croatia Airlines, Edelweiss Air to go to Prague by flight.
- 2 direct buses per day with FlixBus.
- 2 direct flights per day with Eurowings, Smartwings, Avion Express Malta.
Travelling from Osnabrück to Prague: related information
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