Travel Information
Compare bus, train, and flight for Osnabrück to Prague
Omio recommends booking the bus as it is the most popular option from Osnabrück to Prague among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $48 For those with little time, consider booking a flight, which has an average total journey time of 3h 16m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.2 - 0.5kg. Average ticket prices depend on the travel mode: a bus costs an average of $48, while a flight costs an average of $139.
Distance: 314 miles (506 km)
Compare bus with
Most popular Bus | Train | Flight |
|---|---|---|
$48 Average price Cheapest | $81 Average price | $139 Average price |
10h 50m Average total duration 10h 20m Onboard + 30m Additional time* | 7h 54m Average total duration 7h 24m Onboard + 30m Additional time* | 3h 16m Average total duration Fastest 1h 16m Onboard + 2h 0m Additional time* |
0.5 - 1.3kg CO2 emissions | 0.2 - 0.5kg CO2 emissions Lowest | 1.5 - 3.0kg CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Travel optionsfrom Osnabrück to Prague
How to get from Osnabrück to Prague by train, bus or flight.
Our recommendation
The best way to travel from Osnabrück to Prague is by taking a bus because it’s the best combination of price and speed.
FlixBus9:00 PM10h15Osnabrück, Hauptbahnhof7:15 AMPraha, ÚAN Florenc$561One-way0 transfers
Cheapest
FlixBus9:00 PM10h15Osnabrück, Hauptbahnhof7:15 AMPraha, ÚAN Florenc$561One-way0 transfers
Fastest
EW7722:25 PM1h10Cologne Bonn Airport3:35 PMPrague Vaclav Havel Airport$1311One-way0 transfers
Other options
ICE 204 · RJ 17711:23 AM7h52Osnabrück Hbf7:15 PMPrague-Holešovice$1711One-way1 transfer
ICE 1053 · ICE 549 · RJ 3851:53 PM7h32Osnabrück Hbf9:25 PMPrague hlavní nádraží$2261One-way2 transfers
ICE 206 · RJ 3839:23 AM8h02Osnabrück Hbf5:25 PMPrague hlavní nádraží$2441One-way1 transfer
FlixBus · FlixBus1:30 AM10h50Osnabrück, Hauptbahnhof12:20 PMPraha, ÚAN Florenc$591One-way1 transfer
FlixBus · FlixBus1:30 AM11h10Osnabrück, Hauptbahnhof12:40 PMPrague, Central Train Station$591One-way1 transfer
FlixBus · FlixBus8:25 AM14h00Osnabrück, Hauptbahnhof10:25 PMPraha, Černý Most$591One-way1 transfer
EW42018:25 AM1h15Dusseldorf Airport9:40 AMPrague Vaclav Havel Airport$1431One-way0 transfers
EW42057:05 PM1h15Dusseldorf Airport8:20 PMPrague Vaclav Havel Airport$1431One-way0 transfers
KL1796 · KL13536:25 AM4h05Dusseldorf Airport10:30 AMPrague Vaclav Havel Airport$2681One-way1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Osnabrück to Prague
Travel to Prague easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Osnabrück to Prague.

This is compared to other travel options from Osnabrück to Prague:
A bus is $33 less than a train for this route with tickets for a train from Osnabrück to Prague costing on average $81.
A bus is $91 less than a flight for this route with tickets for a flight from Osnabrück to Prague costing on average $139.
Other travel options to Prague take longer:
Train takes on average 7h 54m.
Bus takes on average 10h 50m.
- Around 48 flights per day.
- Around 12 trains per day.
- Around 10 buses per day.
However, we recommend checking specific travel dates for your route between Osnabrück and Prague as scheduled services by bus, train, and flight can vary by season or day of the week.
- Flights mostly depart from Dusseldorf Airport and arrive in Prague Vaclav Havel Airport.
- Trains mostly depart from Osnabrück Hbf and arrive in Prague hlavní nádraží.
- Buses mostly depart from Osnabrück, Hauptbahnhof and arrive in Prague, Central Train Station.
- Travel with Eurowings, Air Baltic to go to Prague by flight.
- Travel with FlixBus to go to Prague by bus.
- Travel with Deutsche Bahn, České dráhy to go to Prague by train.
- 3 direct flights per day with Air Baltic.
- 2 direct buses per day with FlixBus.
Travelling from Osnabrück to Prague: related information
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