- Must visit
Musée des Confluences
A major science and anthropology museum in a striking contemporary building at the confluence of the Rhône and Saône. One of Lyon’s signature cultural sites with strong temporary exhibitions.
Cheapest price
$87
Average price
$101
Fastest journey
2 h 54 m
Average duration
3 h 5 m
Trains per day
7
Distance
292 km
The best way to find a cheap train ticket from Mulhouse to Lyon is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Mulhouse to Lyon will cost around $101 if you buy it on the day, but the cheapest tickets can be found for only $87.
Of the 7 trains that leave Mulhouse for Lyon on Sun, Jun 07, 6 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sun, Jun 07 the direct trains cover the 292 km distance in an average of 3 h 5 m but if you time it right, some trains will get you there in just 2 h 54 m .
On Sun, Jun 07 the slowest trains will take 3 h 18 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
6704+
117773
12179
9877
5539
5537
5539
12179
9877
9879
5537Omio recommends booking the train as it is the most popular option from Mulhouse to Lyon among Omio's users. If you are prioritising price take the bus with prices starting from $22. For those with little time consider booking a train which can get you there in 3h 16m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.3kg. The ticket price range depends on the travel mode: a bus costs an average of $22, and a flight costs an average of $131.
Distance: 181 miles (292 km)
Most popular Train | Bus | Flight | Driving |
|---|---|---|---|
$76 Average price | $37 Average price Cheapest | $340 Average price | $115 Average price (fuel + tolls) |
3h 46m Average total duration Fastest 3h 16m Onboard + 30m Additional time* | 4h 52m Average total duration 4h 22m Onboard + 30m Additional time* | 11h 28m Average total duration 8h 28m Onboard + 3h 0m Additional time* | 4h 3m Average total duration (door-to-door) |
0.1 - 0.3kg CO2 emissions Lowest | 0.3 - 0.7kg CO2 emissions | - CO2 emissions | - CO2 emissions |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Mulhouse to Lyon:
A bus is $40 (€32) less than a train for this route with tickets for a train from Mulhouse to Lyon costing on average $76 (€62).
A bus is $304 (€248) less than a flight for this route with tickets for a flight from Mulhouse to Lyon costing on average $340 (€277).
Other travel options to Lyon take longer:
Bus takes on average 4h 22m.
Flight takes on average 8h 28m.
The journey is about 47m faster (3h 16m by train vs 4h 3m by car) and roughly $39 (€32) cheaper once you factor in fuel and tolls ($76 (€62) vs $115 (€94)). You'll also arrive in the city centre rather than hunting for parking, and you can work, read, or watch the landscape go by instead of concentrating on the road.
Direct services run with SNCF | TGV INOUI, Société Nationale des Chemins de fer Français (SNCF).
Driving is still worth considering if you want to stop along the way or need a car once you arrive.
The table below shows live departures for Mulhouse to Lyon trains for today, Saturday, June 6. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
96218+ 6617+ 9516 | 9:45 AM Mulhouse-Ville | 6h11 | 3:56 PM Lyon Part Dieu | 2 transfers | |
6704+ 17773 | 12:05 PM Mulhouse-Ville | 4h39 | 4:44 PM Lyon Part Dieu | 1 transfer | |
5537 | 1:36 PM Mulhouse-Ville | 3h28 | 5:04 PM Lyon Part Dieu | 0 transfersDirect | |
12177 | 1:36 PM Mulhouse-Ville | 3h28 | 5:04 PM Lyon Part Dieu | 0 transfersDirect | |
96282+ 9512 · 6627 | 1:45 PM Mulhouse-Ville | 6h09 | 7:54 PM Lyon Part Dieu | 2 transfers | |
9580 | 5:09 PM Mulhouse-Ville | 2h49 | 7:58 PM Lyon Part Dieu | 0 transfersDirect | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Trains from Mulhouse to Lyon run on average 9 times per day, taking around 3h 16m. Cheap train tickets for this journey start at $51 (€41) but you can travel from only $22 (€18) by bus.
There are 6 trains per day. The earliest train runs at 05:16, the last at 20:10. The fastest train covers the 181 miles (292 km) distance in 3h 3m.
Distance 181 miles (292 km) |
Average train duration 3h 16m |
Cheapest ticket price $51 (€41) |
Trains per day 9 |
Direct trains 6 |
Fastest train 3h 3m |
First train 5:16 AM |
Last train 8:10 PM |
Cheapest Month Dec |
Cheapest Day Wed |
High Season Apr - Jun |
Low Season Jan - Mar |
Busiest Day Mon |
Least Busy Day Sat |
Best time to book 21 days |
Discover the best of Lyon — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Lyon trip today.
A major science and anthropology museum in a striking contemporary building at the confluence of the Rhône and Saône. One of Lyon’s signature cultural sites with strong temporary exhibitions.
Lyon’s premier fine arts museum, housed in a former abbey near Place des Terreaux. Known for strong collections of painting, sculpture, antiquities, and decorative arts.
Museum of Roman Lyon paired with the city’s ancient theaters on Fourvière hill. A key stop for understanding Lugdunum, the Roman origins of Lyon.
Lyon’s atmospheric old quarter with Renaissance lanes, traboules, and riverfront views. It is the city’s classic strolling area and a top priority for first-time visitors.
One of Europe’s largest open squares and a central meeting point in Lyon. It is a practical orientation stop and a key place for city views toward Fourvière.
Lyon’s flagship urban park with broad walking paths, lake, botanical areas, and a zoo. It is one of the best places in the city for relaxation and scenic walks.
Light dumplings made with pike and panade, usually baked in a rich Nantua crayfish sauce. A classic Lyonnais bouchon specialty.
A traditional salad of frisée lettuce with lardons, croutons, and a poached egg. It is one of the city’s most iconic starter dishes.
Lyon’s famous sausage baked inside a soft brioche dough. It is a beloved charcuterie-based specialty found in many bouchons.
A landmark fine dining institution in Lyon, famed for historic prestige and elegant cuisine rooted in the city’s gastronomic heritage.
The city’s celebrated covered food market, ideal for sampling oysters, charcuterie, cheese, pastries, and many iconic Lyonnais products.
A respected traditional restaurant associated with chef Joseph Viola, celebrated for refined Lyonnais classics in a polished but welcoming setting.
Moderate for France: bakeries and bouchons are fair value, while central hotels and fine dining cost more.
Service is included by law. Leaving small change or 5-10% for great service is appreciated, not required. Round up for taxis.
Official public transport app
Lyon Part-Dieu -> Bellecour, Lyon
Find answers to the most common questions about traveling from Mulhouse to Lyon by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Lyon, this guide helps you travel smarter and with confidence.

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