- Must visit
Musée des Beaux-Arts de Lyon
Major fine arts museum in a former abbey, with strong collections from antiquity to modern art. A core cultural stop in Lyon.
Cheapest price
$64
Average price
$75
Fastest journey
2 h 49 m
Average duration
2 h 57 m
Trains per day
14
Distance
292 km
The best way to find a cheap train ticket from Mulhouse to Lyon is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Mulhouse to Lyon will cost around $75 if you buy it on the day, but the cheapest tickets can be found for only $64.
Of the 14 trains that leave Mulhouse for Lyon on Wed, Jul 22, 9 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Wed, Jul 22 the direct trains cover the 292 km distance in an average of 2 h 57 m but if you time it right, some trains will get you there in just 2 h 49 m .
On Wed, Jul 22 the slowest trains will take 3 h 3 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
12181
5521
6708+
17837
6704+
17831
6706+
17835
12180
9580
12179
9877
12177+
9222Omio recommends booking the train as it is the most popular option from Mulhouse to Lyon among Omio's users. If you are prioritising price take the bus with prices starting from $22. For those with little time consider booking a train which can get you there in 3h 16m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.3kg. The ticket price range depends on the travel mode: a bus costs an average of $22, and a flight costs an average of $130.
Distance: 181 miles (292 km)
Most popular Train | Bus | Flight | Driving |
|---|---|---|---|
$76 Average price | $36 Average price Cheapest | $337 Average price | $114 Average price (fuel + tolls) |
3h 46m Average total duration Fastest 3h 16m Onboard + 30m Additional time* | 4h 52m Average total duration 4h 22m Onboard + 30m Additional time* | 11h 28m Average total duration 8h 28m Onboard + 3h 0m Additional time* | 4h 3m Average total duration (door-to-door) |
0.1 - 0.3kg CO2 emissions Lowest | 0.3 - 0.7kg CO2 emissions | - CO2 emissions | - CO2 emissions |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Mulhouse to Lyon:
A bus is $39 (€32) less than a train for this route with tickets for a train from Mulhouse to Lyon costing on average $76 (€62).
A bus is $301 (€248) less than a flight for this route with tickets for a flight from Mulhouse to Lyon costing on average $337 (€277).
Other travel options to Lyon take longer:
Bus takes on average 4h 22m.
Flight takes on average 8h 28m.
The journey is about 47m faster (3h 16m by train vs 4h 3m by car) and roughly $39 (€32) cheaper once you factor in fuel and tolls ($76 (€62) vs $114 (€94)). You'll also arrive in the city centre rather than hunting for parking, and you can work, read, or watch the landscape go by instead of concentrating on the road.
Direct services run with SNCF | TGV INOUI, Société Nationale des Chemins de fer Français (SNCF).
Driving is still worth considering if you want to stop along the way or need a car once you arrive.
The table below shows live departures for Mulhouse to Lyon trains for today, Tuesday, July 21. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
12179 | On time 9:56 AM Mulhouse-Ville | 3h03 | 12:59 PM Lyon Part Dieu | 0 transfersDirect | |
9877 | On time 9:56 AM Mulhouse-Ville | 3h03 | 12:59 PM Lyon Part Dieu | 0 transfersDirect | |
17771+ 9210 | 10:56 AM Mulhouse-Ville | 3h48 | 2:44 PM Lyon Part Dieu | 1 transfer | |
6704+ 17831 | 11:56 AM Mulhouse-Ville | 3h48 | 3:44 PM Lyon Part Dieu | 1 transfer | |
9879 | 1:57 PM Mulhouse-Ville | 3h06 | 5:03 PM Lyon Part Dieu | 0 transfersDirect | |
12177 | 2:41 PM Mulhouse-Ville | 3h18 | 5:59 PM Lyon Part Dieu | 0 transfersDirect | |
5537 | 2:41 PM Mulhouse-Ville | 3h18 | 5:59 PM Lyon Part Dieu | 0 transfersDirect | |
5537+ 9222 | 2:56 PM Mulhouse-Ville | 3h03 | 5:59 PM Lyon Part Dieu | 1 transfer | |
6706+ 17835 | 3:40 PM Mulhouse-Ville | 4h04 | 7:44 PM Lyon Part Dieu | 1 transfer | |
12180 | 5:09 PM Mulhouse-Ville | 2h49 | 7:58 PM Lyon Part Dieu | 0 transfersDirect | |
9580 | 5:09 PM Mulhouse-Ville | 2h49 | 7:58 PM Lyon Part Dieu | 0 transfersDirect | |
6708+ 17837 | 5:46 PM Mulhouse-Ville | 3h58 | 9:44 PM Lyon Part Dieu | 1 transfer | |
| Wednesday, July 22 | |||||
5521 | 7:52 AM Mulhouse-Ville | 3h07 | 10:59 AM Lyon Part Dieu | 0 transfersDirect | |
12181 | 7:52 AM Mulhouse-Ville | 3h07 | 10:59 AM Lyon Part Dieu | 0 transfersDirect | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Trains from Mulhouse to Lyon run on average 9 times per day, taking around 3h 16m. Cheap train tickets for this journey start at $50 (€41) but you can travel from only $22 (€18) by bus.
There are 6 trains per day. The earliest train runs at 05:16, the last at 20:10. The fastest train covers the 181 miles (292 km) distance in 3h 3m.
Distance 181 miles (292 km) |
Average train duration 3h 16m |
Cheapest ticket price $50 (€41) |
Trains per day 9 |
Direct trains 6 |
Fastest train 3h 3m |
First train 5:16 AM |
Last train 8:10 PM |
Cheapest Month Dec |
Cheapest Day Wed |
High Season Apr - Jun |
Low Season Jan - Mar |
Busiest Day Mon |
Least Busy Day Sat |
Best time to book 21 days |
Discover the best of Lyon — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Lyon trip today.
Major fine arts museum in a former abbey, with strong collections from antiquity to modern art. A core cultural stop in Lyon.
Museum of cinema miniatures and film props in Vieux Lyon. Popular for detailed sets, special-effects history, and family-friendly exhibits.
Excellent free natural history and ethnography museum with fossils, animals, and global cultures. A strong local favorite, especially for families.
Renaissance quarter with cobbled lanes, traboules, courtyards, and major monuments. Essential for atmosphere, history, and walking exploration.
Central peninsula between the Rhône and Saône, packed with elegant streets, squares, shopping, and many of Lyon’s classic city views.
Historic silk-workers’ hill district with stairways, murals, markets, and hidden passageways. Great for local character and city panoramas.
Pike dumplings in a rich crayfish sauce. A Lyon classic from traditional bouchons, prized for its delicate fish texture and luxurious sauce.
Crisp salad of frisée, bacon lardons, croutons, and a poached egg. A staple Lyonnaise bistro dish that reflects the city's hearty cooking style.
Slow-cooked onions with vinegar, often served warm or chilled. This old Lyonnais side dish is traditional in bouchons and pairs well with charcuterie.
Refined dining by Paul Bocuse, known for polished French cuisine and iconic Lyon dishes in an elegant, historic dining room.
Well-known traditional bouchon in Vieux Lyon, praised for generous Lyonnais specialties and a lively old-city atmosphere.
Historic bouchon near Place Bellecour serving quenelles, salade lyonnaise, and classic regional fare in a warm traditional setting.
Moderate for Western Europe: hotels and dining are mid-priced, while public transport is good value for visitors.
Service is usually included. Round up or leave 5-10% for great restaurant service. Round up taxi fares; small change is fine in cafes.
Find answers to the most common questions about traveling from Mulhouse to Lyon by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Lyon, this guide helps you travel smarter and with confidence.

Most Mulhouse to Lyon trains use the Mulhouse-Ville to Lyon Part Dieu station pair, with some services arriving at Lyon-Jean-Macé. Use this guide to compare Mulhouse and Lyon train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Mulhouse-Ville is 1 km from Mulhouse city centre. Public transport options include:
Mulhouse-Ville has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lounge, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, Information Desk, and Luggage Carts.
Food options include: Restaurant Le 17, Le Bistrot du Marché
Free. ATMs are available in the train station.
Ticket office support is available at Mulhouse-Ville. Information desks are located in the main hall.
Luggage storage is available at Mulhouse-Ville. Lost and found is available at the station.
Available at Mulhouse-Ville: Parking, Taxis, WC.
Available at Mulhouse-Ville: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Mulhouse-Ville: Ramps, restrooms.
Nearby hotels include Hotel Bristol Mulhouse, Best Western Hotel de la Bourse, Ibis Mulhouse Ville Gare Centrale.
Mulhouse Dornach is 1 km from Mulhouse city centre. Public transport options include:
Mulhouse Dornach has practical services for this route, including Wifi, Parking, Taxis, Accessibility, WC, Hotel, Ticket Office, Bike Parking, Information Desk, and Luggage Carts.
Free.
Ticket office support is available at Mulhouse Dornach. Information desks are located in the main hall.
Available at Mulhouse Dornach: Parking, Taxis, WC.
Available at Mulhouse Dornach: Bike Parking.
Accessibility facilities are available at Mulhouse Dornach.
Nearby hotels include B&B Hotel Mulhouse Dornach, Ibis Budget Mulhouse Dornach, Hotel Bristol.
Lyon Part Dieu is 1 km from Lyon city centre. Public transport options include:
Lyon Part Dieu has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Ticket Office, Bike Parking, Bike Rental, Car Rental, and Information Desk.
Food options include: Alto Café, Paul, Paul The Café, Starbucks, Exki, Sushi Shop, Carrefour
Free unlimited WiFi. ATMs are located in the station's main hall.
The ticket office is open Mon - Wed: 05:00 - 20:45, Thu - Sat: 05:00 - 21:45, Sun: 06:45 - 21:45. Information desks are located in the station's main hall. .
Luggage storage is luggage lockers are available daily from 06:15 to 23:15. They are located near the station's reception desk. .
Available at Lyon Part Dieu: Parking, Taxis, WC.
Available at Lyon Part Dieu: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Lyon Part Dieu: Complimentary personalized care is available.
Nearby hotels include Radisson Blu Hotel Lyon, Mercure Lyon Center, ibis Styles Lyon Center.
Lyon-Jean-Macé has practical services for this route, including Wifi, Lockers, Parking, Dining, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Information Desk, and Luggage Carts.
Food options include: Le Jean Moulin, Brasserie de l'Est
Free.
Ticket office support is available at Lyon-Jean-Macé. Information desks are located in the main hall.
Luggage storage is available at Lyon-Jean-Macé. Lost and found is available at the station.
Available at Lyon-Jean-Macé: Parking, Taxis, WC.
Available at Lyon-Jean-Macé: Bike Parking, Bike Rental.
Accessibility facilities are available at Lyon-Jean-Macé: Ramps.
Nearby hotels include Ibis Lyon Centre, Hotel des Facultés, Comfort Suites Rive Gauche Lyon Centre.
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