Travel Information
Compare train, bus, and flight for Mulhouse to Lyon
Omio recommends booking the train as it is the most popular option from Mulhouse to Lyon among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $39 For those with little time, consider booking a train, which has an average total journey time of 3h 38m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.1 - 0.3kg. Average ticket prices depend on the travel mode: a bus costs an average of $39, while a flight costs an average of $732.
Distance: 181 miles (292 km)
Compare train with
Most popular Train | Bus | Flight | Driving |
|---|---|---|---|
$90 Average price | $39 Average price Cheapest | $732 Average price | $113 Average price (fuel + tolls) |
3h 38m Average total duration Fastest 3h 8m Onboard + 30m Additional time* | 5h 56m Average total duration 5h 26m Onboard + 30m Additional time* | 5h 12m Average total duration 3h 12m Onboard + 2h 0m Additional time* | 4h 3m Average total duration (door-to-door) |
0.1 - 0.3kg CO2 emissions Lowest | 0.3 - 0.7kg CO2 emissions | - CO2 emissions | - CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Compare ways to travel from Mulhouse to Lyon
Compare the available ways to get from Mulhouse to Lyon, with the key details around price, speed, convenience, and direct service.
This is compared to other travel options from Mulhouse to Lyon:
A bus is $52 (€44) less than a train for this route with tickets for a train from Mulhouse to Lyon costing on average $90 (€76).
A bus is $694 (€582) less than a flight for this route with tickets for a flight from Mulhouse to Lyon costing on average $732 (€614).
Other travel options to Lyon take longer:
Flight takes on average 5h 12m.
Bus takes on average 5h 56m.
The journey is about 55m faster (3h 8m by train vs 4h 3m by car) and roughly $23 (€20) cheaper once you factor in fuel and tolls ($90 (€76) vs $113 (€95)). You'll also arrive in the city centre rather than hunting for parking, and you can work, read, or watch the landscape go by instead of concentrating on the road.
Driving is still worth considering if you want to stop along the way or need a car once you arrive.
Travel optionsfrom Mulhouse to Lyon
How to get from Mulhouse to Lyon by train, bus or flight.
Our recommendation
The best way to travel from Mulhouse to Lyon is by taking a bus because it’s the best combination of price and speed.
FlixBus7:30 AM 5h20 Mulhouse, Gare Centrale 12:50 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) $29 1 One-way 0 transfers
Cheapest
FlixBus7:30 AM 5h20 Mulhouse, Gare Centrale 12:50 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) $29 1 One-way 0 transfers
Fastest
98779:56 AM 3h03 Mulhouse-Ville 12:59 PM Lyon Part Dieu $67 1 One-way 0 transfers
Other options
55372:41 PM 3h18 Mulhouse-Ville 5:59 PM Lyon Part Dieu $57 1 One-way 0 transfers
121772:41 PM 3h18 Mulhouse-Ville 5:59 PM Lyon Part Dieu $57 1 One-way 0 transfers
98791:57 PM 3h06 Mulhouse-Ville 5:03 PM Lyon Part Dieu $64 1 One-way 0 transfers
FlixBus3:05 AM 5h10 Mulhouse, Gare Centrale 8:15 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) $31 1 One-way 0 transfers
AF1293 · AF73702:35 PM 7h40 EuroAirport Basel Mulhouse Freiburg 10:15 PM Lyon Saint Exupery Airport $259 1 One-way 1 transfer
AF3195 · AF31476:00 AM 7h25 EuroAirport Basel Mulhouse Freiburg 1:25 PM Lyon Saint Exupery Airport $271 1 One-way 1 transfer
AF3186 · AF314810:10 AM 7h30 EuroAirport Basel Mulhouse Freiburg 5:40 PM Lyon Saint Exupery Airport $375 1 One-way 1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Mulhouse to Lyon
Travel to Lyon easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Mulhouse to Lyon.

This is compared to other travel options from Mulhouse to Lyon:
A bus is $52 (€44) less than a train for this route with tickets for a train from Mulhouse to Lyon costing on average $90 (€76).
A bus is $694 (€582) less than a flight for this route with tickets for a flight from Mulhouse to Lyon costing on average $732 (€614).
Other travel options to Lyon take longer:
Flight takes on average 5h 12m.
Bus takes on average 5h 56m.
- Around 14 flights per day.
- Around 9 trains per day.
- Around 5 buses per day.
However, we recommend checking specific travel dates for your route between Mulhouse and Lyon as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from EuroAirport Basel Mulhouse Freiburg and arrive in Lyon Saint Exupery Airport.
- Trains mostly depart from Mulhouse-Ville and arrive in Lyon Part Dieu.
- Buses mostly depart from Mulhouse, Gare Centrale and arrive in Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland).
- Travel with SNCF | TGV INOUI, TER, SNCF TER | Operated by SNCF Voyageurs 1187, SNCF | TGV Lyria, SNCF | Intercités to go to Lyon by train.
- Travel with KLM, Air France, KLM Cityhopper, British Airways, Global Supply Systems to go to Lyon by flight.
- Travel with FlixBus, BlaBlaCar Bus to go to Lyon by bus.
- 6 direct trains per day with SNCF | TGV INOUI.
- 5 direct buses per day with FlixBus, BlaBlaCar Bus.
Travelling from Mulhouse to Lyon: related information
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