The cheapest and fastest trains from Mannheim to Domodossola
Cheapest price
$185
Average price
$185
Fastest journey
5 h 26 m
Average duration
5 h 32 m
Trains per day
2
Distance
376 km
The best way to find a cheap train ticket from Mannheim to Domodossola is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Mannheim to Domodossola will cost around $185 if you buy it on the day, but the cheapest tickets can be found for only $185.
It's difficult to get from Mannheim to Domodossola without transferring at least once.




Live departures
Mannheim to Domodossola train times
The table below shows live departures for Mannheim to Domodossola trains for today, Wednesday, February 4. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 2:46 PM Mannheim | 5h26 | 8:12 PM Domodossola | 1 transfer | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Mannheim to Domodossola by train
Compare train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Feb 05
Feb 06
Feb 07
Feb 08
Feb 09
Feb 10
Feb 11
Why should you book Mannheim to Domodossola trains with Omio?
Why book with Omio vs Deutsche Bahn?
- Compare with other providers: On Omio, you can not only buy tickets for Deutsche Bahn, but also compare tickets for the likes of to find the best option for your trip from Mannheim to Domodossola.
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Why book with Omio over Trainline or Wanderu?
Journey information
Overview: Train from Mannheim to Domodossola
Trains from Mannheim to Domodossola run on average 6 times per day, taking around 4h 56m. Cheap train tickets for this journey start at $184 (€146) if you book in advance.
The earliest train runs at 04:03, the last at 20:48. The fastest train covers the 233 miles (376 km) distance in 5h 26m.
Distance 233 miles (376 km) |
Average train duration 4h 56m |
Cheapest ticket price $184 (€146) |
Trains per day 6 |
Fastest train 5h 26m |
First train 04:03 |
Last train 20:48 |
Train companies: Deutsche Bahn from Mannheim to Domodossola trainsDeutsche Bahn trains will get you between Mannheim and Domodossola from $184 (€146). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Deutsche Bahn
A Bordrestaurant (restaurant car) where you can sit and eat.
A Bordbistro (bistro bar) with snacks, hot meals, and drinks to-go.
At-seat service in 1st class: staff will take your order and serve food/drinks directly to your seat.
Regional trains (RE / RB / S-Bahn):
No onboard catering.
You’re welcome to bring your own food and drinks.
Not included by default.
You can add a seat reservation when booking (recommended for busy routes).
Costs around €4.90 per seat (or €5.90 if booked separately later).
First Class:
Yes, always included in the ticket price.
Allowed for free if they can fit in a transport box (max. size: hand luggage).
Must stay in the box for the entire journey.
Large dogs:
Require a separate (paid) ticket — typically half the price of a regular second-class ticket.
Must be leashed and wear a muzzle while on the train.
Cannot sit on seats.
Assistance dogs:
Travel free of charge.
Do not need a muzzle or leash if medically not required.
Allowed to accompany the passenger at all times.
FAQs: Trains from Mannheim to Domodossola
Find answers to the most common questions about traveling from Mannheim to Domodossola by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Domodossola, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Mannheim to Domodossola
- Monday: 06:00 - 21:00
- Tuesday: 06:00 - 21:00
- Wednesday: 06:00 - 21:00
- Thursday: 06:00 - 21:00
- Friday: 06:00 - 21:00
- Saturday: 08:00 - 20:30
- Sunday: 08:00 - 20:30
- Safran Persisch-Afghanische Spezialitäten
- Corner
- Liman Döner
- Kaschmir-Tandoori
- Central
- Leonardo Hotel Mannheim City Center
- InterCityHotel Mannheim
- City Hotel
- 6:00 AM - 8:00 PM Monday - Sunday
- Free
- The car park is open 7 days a week, accessible from the main entrance.
- Ristorante La Meridiana
- Osteria Vecchio Borgo
- Outside the main entrance.
- Elevators, ramps.
- €1
- Hotel Corona
- Hotel Ristorante Eurossola
- Hotel Domodossola
- Located in the main hall
- Avis
- Europcar
- Located in the main hall
- Free
- Hall 1: main entrance, platform 1-5 for trains to Switzerland and regional destinations
- Train: Regional and Eurocity trains
- Bus: Several local lines available
Most popular train connections from Mannheim
More options for your journey from Mannheim to Domodossola
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