- Must visit
Museo di Palazzo San Francesco
Main civic museum in a Renaissance palace, presenting archaeology, art, and history tied to Domodossola and the Ossola valleys.
Cheapest price on Sep 18
€46
Average ticket price on Sep 18
€70
Fastest journey on Sep 18
6 h
Average journey duration on Sep 18
6 h 4 m
Trains on Sep 18
65
Distance
577 km
The best way to find a cheap train ticket from Rome Termini to Domodossola is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Rome Termini to Domodossola will cost around €70 if you buy it on the day, but the cheapest tickets can be found for only €46.
It's difficult to get from Rome Termini to Domodossola without transferring at least once.
9966+
Autobus EC064
9966+
Autobus EC066
9966+
Autobus EC042
9968+
Autobus EC042
9968+
Autobus EC064
FRECCIAROSSA 9640+
Autobus EC046
FRECCIAROSSA 9624+
Autobus EC064
FRECCIAROSSA 9636+
Autobus EC066
FRECCIAROSSA 9622+
Regionale TRENORD 2426 · Autobus TRENORD 2426A
FRECCIAROSSA 9616+
Autobus EC042Omio recommends booking the train as it is the most popular option from Rome Termini to Domodossola among Omio's users. If you are prioritising price, take the train, with an average ticket price of €21 For those with little time, consider booking a flight, which has an average total journey time of 4h 49m. Average ticket prices depend on the travel mode: a train costs an average of €21, while a flight costs an average of €325.
Distance: 358 miles (577 km)
Most popular Train | Flight | Driving |
|---|---|---|
€21 Average price Cheapest | €325 Average price | €116 Average price (fuel + tolls) |
5h 54m Average total duration 5h 24m Onboard + 30m Additional time* | 4h 49m Average total duration Fastest 2h 49m Onboard + 2h 0m Additional time* | 7h 6m Average total duration (door-to-door) |
![]() Most popular train company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Rome Termini to Domodossola:
A train is €304 less than a flight for this route with tickets for a flight from Rome Termini to Domodossola costing on average €325.
Other travel options to Domodossola take longer:
Train takes on average 5h 24m.
The journey is about 1h 42m faster (5h 24m by train vs 7h 6m by car) and roughly €95 cheaper once you factor in fuel and tolls (€21 vs €116). You'll also arrive in the city centre rather than hunting for parking, and you can work, read, or watch the landscape go by instead of concentrating on the road.
Driving is still worth considering if you want to stop along the way or need a car once you arrive.
The table below shows live departures for Rome Termini to Domodossola trains for tomorrow, Friday, September 18. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
9904+ Autobus EC066 | 5:35 AM Rome Termini | 13h45 | 7:20 PM Domodossola station | 1 transfer | |
9904+ Autobus EC042 | 5:35 AM Rome Termini | 8h45 | 2:20 PM Domodossola station | 1 transfer | |
9904+ Autobus EC064 | 5:35 AM Rome Termini | 10h45 | 4:20 PM Domodossola station | 1 transfer | |
FRECCIAROSSA 9682+ Regionale TRENORD 2418 · Autobus TRENORD 2418A | 5:35 AM Rome Termini | 6h15 | 11:50 AM Domodossola station | 2 transfers | |
9966+ Autobus EC064 | 6:25 AM Rome Termini | 9h55 | 4:20 PM Domodossola station | 1 transfer | |
9966+ Autobus EC066 | 6:25 AM Rome Termini | 12h55 | 7:20 PM Domodossola station | 1 transfer | |
9966+ Autobus EC042 | 6:25 AM Rome Termini | 7h55 | 2:20 PM Domodossola station | 1 transfer | |
9908+ Autobus EC042 | 6:35 AM Rome Termini | 7h45 | 2:20 PM Domodossola station | 1 transfer | |
9908+ Autobus EC066 | 6:35 AM Rome Termini | 12h45 | 7:20 PM Domodossola station | 1 transfer | |
9908+ Autobus EC064 | 6:35 AM Rome Termini | 9h45 | 4:20 PM Domodossola station | 1 transfer | |
9968+ Autobus EC042 | 7:00 AM Rome Termini | 7h20 | 2:20 PM Domodossola station | 1 transfer | |
9968+ Autobus EC064 | 7:00 AM Rome Termini | 9h20 | 4:20 PM Domodossola station | 1 transfer | |
9968+ Autobus EC066 | 7:00 AM Rome Termini | 12h20 | 7:20 PM Domodossola station | 1 transfer | |
9970+ Autobus EC064 | 7:25 AM Rome Termini | 8h55 | 4:20 PM Domodossola station | 1 transfer | |
9970+ Autobus EC042 | 7:25 AM Rome Termini | 6h55 | 2:20 PM Domodossola station | 1 transfer | |
9970+ Autobus EC066 | 7:25 AM Rome Termini | 11h55 | 7:20 PM Domodossola station | 1 transfer | |
9912+ Autobus EC042 | 7:35 AM Rome Termini | 6h45 | 2:20 PM Domodossola station | 1 transfer | |
9912+ Autobus EC064 | 7:35 AM Rome Termini | 8h45 | 4:20 PM Domodossola station | 1 transfer | |
9912+ Autobus EC066 | 7:35 AM Rome Termini | 11h45 | 7:20 PM Domodossola station | 1 transfer | |
9972+ Autobus EC064 | 8:00 AM Rome Termini | 8h20 | 4:20 PM Domodossola station | 1 transfer | |
9972+ Autobus EC066 | 8:00 AM Rome Termini | 11h20 | 7:20 PM Domodossola station | 1 transfer | |
9972+ Autobus EC042 | 8:00 AM Rome Termini | 6h20 | 2:20 PM Domodossola station | 1 transfer | |
FRECCIAROSSA 9616+ Autobus EC042 | 8:15 AM Rome Termini | 6h05 | 2:20 PM Domodossola station | 1 transfer | |
9916+ Autobus EC046 | 8:35 AM Rome Termini | 11h45 | 8:20 PM Domodossola station | 1 transfer | |
9916+ Autobus EC064 | 8:35 AM Rome Termini | 7h45 | 4:20 PM Domodossola station | 1 transfer | |
9916+ Autobus EC066 | 8:35 AM Rome Termini | 10h45 | 7:20 PM Domodossola station | 1 transfer | |
9974+ Autobus EC064 | 9:00 AM Rome Termini | 7h20 | 4:20 PM Domodossola station | 1 transfer | |
9974+ Autobus EC046 | 9:00 AM Rome Termini | 11h20 | 8:20 PM Domodossola station | 1 transfer | |
9974+ Autobus EC066 | 9:00 AM Rome Termini | 10h20 | 7:20 PM Domodossola station | 1 transfer | |
9920+ Autobus EC064 | 9:40 AM Rome Termini | 6h40 | 4:20 PM Domodossola station | 1 transfer | |
9920+ Autobus EC046 | 9:40 AM Rome Termini | 10h40 | 8:20 PM Domodossola station | 1 transfer | |
9920+ Autobus EC066 | 9:40 AM Rome Termini | 9h40 | 7:20 PM Domodossola station | 1 transfer | |
FRECCIAROSSA 9622+ Regionale TRENORD 2426 · Autobus TRENORD 2426A | 9:45 AM Rome Termini | 6h05 | 3:50 PM Domodossola station | 2 transfers | |
9976+ Autobus EC064 | 10:00 AM Rome Termini | 6h20 | 4:20 PM Domodossola station | 1 transfer | |
9976+ Autobus EC066 | 10:00 AM Rome Termini | 9h20 | 7:20 PM Domodossola station | 1 transfer | |
9976+ Autobus EC046 | 10:00 AM Rome Termini | 10h20 | 8:20 PM Domodossola station | 1 transfer | |
FRECCIAROSSA 9624+ Autobus EC064 | 10:15 AM Rome Termini | 6h05 | 4:20 PM Domodossola station | 1 transfer | |
Intercity 588 · Intercity 608+ Autobus EC046 | 10:15 AM Rome Termini | 10h05 | 8:20 PM Domodossola station | 2 transfers | |
9924+ Autobus EC066 | 10:40 AM Rome Termini | 8h40 | 7:20 PM Domodossola station | 1 transfer | |
9924+ Regionale Veloce 2034 · Regionale 11438 | 10:40 AM Rome Termini | 9h27 | 8:07 PM Domodossola station | 2 transfers | |
9924+ Autobus EC046 | 10:40 AM Rome Termini | 9h40 | 8:20 PM Domodossola station | 1 transfer | |
FRECCIAROSSA 9626+ Regionale Veloce 2028 · Regionale 11432 | 10:45 AM Rome Termini | 6h32 | 5:17 PM Domodossola station | 2 transfers | |
9978+ Regionale Veloce 2034 · Regionale 11438 | 11:01 AM Rome Termini | 9h06 | 8:07 PM Domodossola station | 2 transfers | |
9978+ Autobus EC066 | 11:01 AM Rome Termini | 8h19 | 7:20 PM Domodossola station | 1 transfer | |
9978+ Autobus EC046 | 11:01 AM Rome Termini | 9h19 | 8:20 PM Domodossola station | 1 transfer | |
9928+ Autobus EC046 | 11:40 AM Rome Termini | 8h40 | 8:20 PM Domodossola station | 1 transfer | |
9928+ Regionale Veloce 2034 · Regionale 11438 | 11:40 AM Rome Termini | 8h27 | 8:07 PM Domodossola station | 2 transfers | |
9928+ Autobus EC066 | 11:40 AM Rome Termini | 7h40 | 7:20 PM Domodossola station | 1 transfer | |
9980+ Regionale Veloce 2034 · Regionale 11438 | 12:05 PM Rome Termini | 8h02 | 8:07 PM Domodossola station | 2 transfers | |
9980+ Autobus EC046 | 12:05 PM Rome Termini | 8h15 | 8:20 PM Domodossola station | 1 transfer | |
9980+ Autobus EC066 | 12:05 PM Rome Termini | 7h15 | 7:20 PM Domodossola station | 1 transfer | |
9932+ Autobus EC046 | 12:35 PM Rome Termini | 7h45 | 8:20 PM Domodossola station | 1 transfer | |
9932+ Autobus EC066 | 12:35 PM Rome Termini | 6h45 | 7:20 PM Domodossola station | 1 transfer | |
9932+ Regionale Veloce 2034 · Regionale 11438 | 12:35 PM Rome Termini | 7h32 | 8:07 PM Domodossola station | 2 transfers | |
9982+ Autobus EC066 | 1:01 PM Rome Termini | 6h19 | 7:20 PM Domodossola station | 1 transfer | |
9982+ Regionale Veloce 2034 · Regionale 11438 | 1:01 PM Rome Termini | 7h06 | 8:07 PM Domodossola station | 2 transfers | |
9982+ Autobus EC046 | 1:01 PM Rome Termini | 7h19 | 8:20 PM Domodossola station | 1 transfer | |
FRECCIAROSSA 9636+ Autobus EC066 | 1:15 PM Rome Termini | 6h05 | 7:20 PM Domodossola station | 1 transfer | |
8134+ Regionale Veloce 2036 · Regionale 11440 | 1:40 PM Rome Termini | 7h37 | 9:17 PM Domodossola station | 2 transfers | |
8134+ Autobus EC046 | 1:40 PM Rome Termini | 6h40 | 8:20 PM Domodossola station | 1 transfer | |
FRECCIAROSSA 9638+ Regionale Veloce 2034 · Regionale 11438 | 1:45 PM Rome Termini | 6h22 | 8:07 PM Domodossola station | 2 transfers | |
9984+ Regionale Veloce 2036 · Regionale 11440 | 2:05 PM Rome Termini | 7h12 | 9:17 PM Domodossola station | 2 transfers | |
9984+ Autobus EC046 | 2:05 PM Rome Termini | 6h15 | 8:20 PM Domodossola station | 1 transfer | |
FRECCIAROSSA 9640+ Autobus EC046 | 2:20 PM Rome Termini | 6h00 | 8:20 PM Domodossola station | 1 transfer | |
FRECCIAROSSA 9642+ Regionale Veloce 2036 · Regionale 11440 | 2:45 PM Rome Termini | 6h32 | 9:17 PM Domodossola station | 2 transfers | |
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Trains from Rome Termini to Domodossola run on average 57 times per day, taking around 5h 24m. Cheap train tickets for this journey start at €10 if you book in advance.
The earliest train runs at 02:40, the last at 21:27. The fastest train covers the 358 miles (577 km) distance in 4h 44m.
Distance 358 miles (577 km) |
Average train duration 5h 24m |
Cheapest ticket price €10 |
Trains per day 57 |
Fastest train 4h 44m |
First train 2:40 AM |
Last train 9:27 PM |
Cheapest Month Nov |
Cheapest Day Sat |
High Season Apr - Jun |
Low Season Jan - Mar |
Busiest Day Thu |
Least Busy Day Wed |
Discover the best of Domodossola — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Domodossola trip today.
Main civic museum in a Renaissance palace, presenting archaeology, art, and history tied to Domodossola and the Ossola valleys.
Prestigious exhibition venue hosting major temporary shows in a restored palace, a key destination for art lovers in Ossola.
Museum route at the sacred mount interpreting chapels, devotion, and local religious heritage in a UNESCO setting.
Domodossola's arcaded medieval market square, lively and photogenic, ideal for architecture, atmosphere, and people-watching.
Historic old town lanes with arcades and stone houses, best explored on foot for local character and hidden details.
Scenic pilgrimage path climbing to the sacred mount, combining chapels, woodland, and rewarding panoramic viewpoints.
Hearty mountain polenta from Ossola, often served with cheese, butter, sausage, or game. It is a staple of local Alpine cooking and cold-weather meals.
Rich risotto made with local red wine from nearby northern Piedmont. It reflects the region's rice culture and love of robust mountain flavors.
Air-dried cured ham from the Ossola valleys, prized for its delicate alpine flavor. It is a classic local salumi served as an antipasto.
Refined dining venue focused on Piedmont and mountain cuisine, with careful presentation and a more elegant setting.
Historic, traditional restaurant in Domodossola known for Ossola specialties, local wines, and a warm alpine atmosphere.
Casual and popular spot for pizza and Italian classics, suitable for relaxed meals in the town center.
Moderate for northern Italy. Meals and hotels are usually cheaper than Milan or Lake Como, while local transit and coffee stay fairly reasonable for tourists.
Service is often included or covered by coperto. Rounding up or leaving €1-2 at cafes is enough; 5-10% in restaurants is optional for great service. Taxis usually get the fare rounded up.
Official public transport app
Domodossola Railway Station -> Piazza del Mercato, Domodossola
Find answers to the most common questions about traveling from Rome Termini to Domodossola by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Domodossola, this guide helps you travel smarter and with confidence.

Most Rome Termini to Domodossola trains use the Roma Termini to Domodossola station pair. Use this guide to compare Rome Termini and Domodossola train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Roma Termini is 1 km from Rome city centre. Public transport options include:
Roma Termini has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Ticket Office, Bike Parking, Car Rental, and Information Desk.
Food options include: Acafe, Moka Café, Roadhouse Grill, McDonald's, Gusto, Chef Express, Coop Minimarket, Mercato Centrale
Free WiFi in the station. ATMs are there are ATMs in various locations around the station.
The ticket office is open Mon - Sun: 06:30 - 22:00. Information desks are located near Platform 24.
Luggage storage is provided by KiPoint and located on Platform 24. Open every day from 06:00 to 23:00.
Available at Roma Termini: Parking, Taxis, WC.
Available at Roma Termini: Bike Parking, Car Rental.
Accessibility facilities are available at Roma Termini: The Sala Blu, Trenitalia's office of assistance for disabled travelers, is located next to Platform 1.
Nearby hotels include Archi di Roma Guest House, Gemma di Roma, The Liberty Boutique Hotel.
Domodossola has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Car Rental, Information Desk, and Luggage Carts.
Food options include: Ristorante La Meridiana, Osteria Vecchio Borgo
Free. ATMs are available in the train station.
Ticket office support is available at Domodossola. Information desks are located in the main hall.
Luggage storage is available at Domodossola. Lost and found is available at the station.
Available at Domodossola: Parking, Taxis, WC.
Available at Domodossola: Bike Parking, Car Rental.
Accessibility facilities are available at Domodossola: Elevators, ramps.
Nearby hotels include Hotel Corona, Hotel Ristorante Eurossola, Hotel Domodossola.
Here are some other resources that might have the information you need