- Must visit
Museo di Palazzo San Francesco
Main civic museum in a Renaissance palace, presenting archaeology, art, and history tied to Domodossola and the Ossola valleys.
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The cheapest and fastest trains from Florence Santa Maria Novella to Domodossola
Showing times, prices and bookable tickets for Sep 20
Cheapest price on Sep 20
$51
Average ticket price on Sep 20
$67
Fastest journey on Sep 20
7 h 59 m
Average journey duration on Sep 20
8 h 50 m
Trains on Sep 20
4
Distance
349 km
Cheap tickets
The best way to find a cheap train ticket from Florence Santa Maria Novella to Domodossola is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Florence Santa Maria Novella to Domodossola will cost around $67 if you buy it on the day, but the cheapest tickets can be found for only $51.
Fast trains
It's difficult to get from Florence Santa Maria Novella to Domodossola without transferring at least once.
Regionale 17800 · Regionale Veloce TTPER 2460+
Autobus EC0424:32 AM9h48Florence Santa Maria Novella2:20 PMDomodossola station$511One-way2 transfers
Intercity 580+Autobus EC0648:21 AM7h59Florence Santa Maria Novella4:20 PMDomodossola station$641One-way1 transfer- Regionale 94455+Intercity 608+Autobus EC04611:40 AM8h40Florence Santa Maria Novella8:20 PMDomodossola station$741One-way2 transfers
- Regionale Veloce 4021+Intercity 670+Autobus EC06610:28 AM8h52Florence Santa Maria Novella7:20 PMDomodossola station$761One-way2 transfers
- Intercity 580+Autobus EC0648:21 AM7h59Florence Santa Maria Novella4:20 PMDomodossola station$641One-way1 transfer
- Regionale 94455+Intercity 608+Autobus EC04611:40 AM8h40Florence Santa Maria Novella8:20 PMDomodossola station$741One-way2 transfers
- Regionale Veloce 4021+Intercity 670+Autobus EC06610:28 AM8h52Florence Santa Maria Novella7:20 PMDomodossola station$761One-way2 transfers
- Regionale 17800 · Regionale Veloce TTPER 2460+Autobus EC0424:32 AM9h48Florence Santa Maria Novella2:20 PMDomodossola station$511One-way2 transfers
Travel Information
Compare bus, train, and flight for Florence Santa Maria Novella to Domodossola
Omio recommends booking the train as it is the most popular option from Florence Santa Maria Novella to Domodossola among Omio's users. If you are prioritising price, take the train, with an average ticket price of $76 For those with little time, consider booking a flight, which has an average total journey time of 4h 47m. Average ticket prices depend on the travel mode: a train costs an average of $76, while a flight costs an average of $426.
Distance: 216 miles (349 km)
Compare train with
Most popular Train | Flight | Driving |
|---|---|---|
$76 Average price Cheapest | $426 Average price | $128 Average price (fuel + tolls) |
5h 25m Average total duration 4h 55m Onboard + 30m Additional time* | 4h 47m Average total duration Fastest 2h 47m Onboard + 2h 0m Additional time* | 4h 26m Average total duration (door-to-door) |
 Most popular train company |  Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
The cheapest way to travel from Florence Santa Maria Novella to Domodossola is a train with an average price of $76.
This is compared to other travel options from Florence Santa Maria Novella to Domodossola:
A train is $349 less than a flight for this route with tickets for a flight from Florence Santa Maria Novella to Domodossola costing on average $426.
The fastest way to travel from Florence Santa Maria Novella to Domodossola is by flight with an average journey time of 2h 47m.
Other travel options to Domodossola take longer:
Train takes on average 4h 55m.
It's helpful to compare your options as there are 3 ways to travel between Florence Santa Maria Novella and Domodossola including taking a bus, train, and flight.
We recommend using the train as it is the most popular way to get from Florence Santa Maria Novella to Domodossola among Omio's users.
Take the train. It's the cheaper option, and the extra time on board is usually more relaxing than driving it.
Tickets start at around $76 compared to roughly $128 in fuel and tolls — a saving of about $52. The journey takes 4h 55m versus 4h 26m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
Live departures
Florence Santa Maria Novella to Domodossola train times
The table below shows live departures for Florence Santa Maria Novella to Domodossola trains for today, Saturday, September 19. You can also manually refresh the results below to see updated train journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| FRECCIAROSSA 9320+Regionale TRENORD 2438 · Autobus TRENORD 4438A | 5:10 PM Florence Santa Maria Novella | 4h42 | 9:52 PM Domodossola station | 2 transfers | |
| FRECCIAROSSA 9588+Regionale TRENORD 2440 · Autobus TRENORD 4440A | 5:55 PM Florence Santa Maria Novella | 4h57 | 10:52 PM Domodossola station | 2 transfers | |
| FRECCIAROSSA 9552+Regionale TRENORD 2442 · Autobus TRENORD 4442A | 6:55 PM Florence Santa Maria Novella | 4h57 | 11:52 PM Domodossola station | 2 transfers | |
| Sunday, September 20 | |||||
| Regionale 17800 · Regionale Veloce TTPER 2460+Autobus EC042 | 4:32 AM Florence Santa Maria Novella | 9h48 | 2:20 PM Domodossola station | 2 transfers | |
| Intercity 580+Autobus EC064 | 8:21 AM Florence Santa Maria Novella | 7h59 | 4:20 PM Domodossola station | 1 transfer | |
| Regionale Veloce 4021+Intercity 670+Autobus EC066 | 10:28 AM Florence Santa Maria Novella | 8h52 | 7:20 PM Domodossola station | 2 transfers | |
| Regionale 94455+Intercity 608+Autobus EC046 | 11:40 AM Florence Santa Maria Novella | 8h40 | 8:20 PM Domodossola station | 2 transfers | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Florence Santa Maria Novella to Domodossola by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Florence Santa Maria Novella to Domodossola trains with Omio?
Intercity as well as Frecciarossa or Regionale offer trains services from Florence Santa Maria Novella to Domodossola.
Omio is the only official third party seller for Intercity tickets.
Why book with Omio vs Intercity?
- Compare with other providers: On Omio, you can not only buy tickets for Intercity, but also compare tickets for the likes of Frecciarossa or Regionale to find the best option for your trip from Florence Santa Maria Novella to Domodossola.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Intercity with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Florence Santa Maria Novella to Domodossola.
Journey information
Overview: Train from Florence Santa Maria Novella to Domodossola
ItalyItaly
Trains from Florence Santa Maria Novella to Domodossola run on average 8 times per day, taking around 4h 55m. Cheap train tickets for this journey start at $42 if you book in advance.
The earliest train runs at 02:30, the last at 06:21. The fastest train covers the 216 miles (349 km) distance in 3h 34m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 216 miles (349 km) |
Average train duration 4h 55m |
Cheapest ticket price $42 |
Trains per day 8 |
Fastest train 3h 34m |
First train 2:30 AM |
Last train 6:21 AM |
Cheapest Month Jan |
Cheapest Day Thu |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Thu |
Least Busy Day Tue |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Train companies: Frecciarossa, Regionale, Intercity from Florence Santa Maria Novella to Domodossola trainsFrecciarossa, Regionale, Intercity trains will get you between Florence Santa Maria Novella and Domodossola from $42. With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Frecciarossa
About
Step on board a Frecciarossa train and relax as you travel across Italy. Trenitalia’s Frecciarossa high-speed trains make around 200 connections across the country each day and are renowned for their comfort, speed, and reduced environmental impact. Reaching speeds of up to 186 mph (300 km/h), they connect major destinations such as Rome, Florence, Milan, Venice, and Naples quickly and efficiently. When booking your Frecciarossa journey, you can choose between four classes: Standard, Premium, Business, and Executive. While each class offers different levels of comfort, all provide free Wi-Fi access, power outlets, air conditioning, bathrooms, luggage storage, onboard entertainment, and restaurant and bar services. Ticket options include Super Economy, Economy, and Base, making it easy to find the right balance of comfort and price for your trip.
Luggage & cancellation policy
Average Frecciarossa Duration
3h 34m
Cheapest Frecciarossa Price
$74
Frecciarossa frequency
4 a day
Luggage included
1 carry-on bag and 1 suitcase per passenger
Luggage storage
Overhead racks, dedicated luggage areas at carriage ends, under seats
Cancellation Policy
Refund policy depends on ticket type
Refund
Full refund provided for canceled trains
Amenities on board the train
Wifi
Food sold onboard
Restaurant car with full meals, bar service with snacks and beverages, at-seat service in Executive class
Seat reservation
Included in Executive class, optional fee for other classes
Toilets
USB plugs
Accessibility
Wheelchair spaces, accessible toilets, assistance service available
Pets
Small pets in carriers travel free, larger dogs require paid ticket and muzzle, service animals free
Quiet zone
Regionale
About
Regionale is the regional train service of national carrier Trenitalia connecting all of Italy. It is the most convinient way to travel to both big cities and the smallest villages all over the Italian country. The regional trains have different names depending on the region they serve, such as Treno Regionale Veloce (TRV) and Treno Regionale Lento (TRL). Treno Rock and Treno pop are the two new trains part of Trenitalia regionale fleet. Trenitalia Regionale offers a variety of ticket types, including single tickets (economy and standard), return tickets, and season tickets. Onboard facilities include free Wi-Fi, air conditioning, and power sockets. The most popular routes for Regionale are between Rome and Milan, Naples and Florence, and Turin and Venice.
Luggage & cancellation policy
Average Regionale Duration
4h 15m
Cheapest Regionale Price
$42
Regionale frequency
2 a day
Luggage included
Free hand luggage allowance included in ticket price
Luggage storage
Overhead racks and designated luggage areas between seats
Cancellation Policy
According to ticket conditions
Refund
Full refund provided
Amenities on board the train
Wifi
Food sold onboard
Bar service available on some trains with snacks and beverages
Seat reservation
Seat reservation included in ticket price for most services
Toilets
USB plugs
Accessibility
Wheelchair spaces and assistance available for passengers with reduced mobility
Pets
Small pets in carriers travel free. Larger dogs require paid ticket and muzzle
Quiet zone
Intercity
About
Trenitalia Intercity is a high-speed train service operated by the Italian national railway company, Trenitalia. It operates throughout the country, with services running from early morning to late evening. The Intercity trains come in two types: the Intercity Plus, which is the fastest and most comfortable, and the Intercity, which is slightly slower but still offers a comfortable journey. Onboard facilities include air conditioning, power sockets, Wi-Fi, and a bar service. There are several ticket types available, including Standard, Super Economy, and Business. The most popular routes for Trenitalia Intercity are from Rome to Milan, Naples to Florence, and Turin to Venice.
Luggage & cancellation policy
Average Intercity Duration
5h 33m
Cheapest Intercity Price
$58
Intercity frequency
1 a day
Luggage included
2 pieces of luggage up to 30kg total
Luggage storage
Overhead racks and designated luggage areas at end of carriages
Cancellation Policy
According to ticket conditions
Refund
Full refund provided
Amenities on board the train
Wifi
Food sold onboard
Restaurant car with hot meals and snacks, trolley service in some trains. But do not count on the presence of a buffet car. So if having access to food and drink on the train is important to you, it’s best to bring your own refreshments onboard.
Seat reservation
Seat reservation included in ticket price for most routes
Toilets
USB plugs
Accessibility
Wheelchair spaces and accessible toilets available
Pets
Small pets in carriers allowed free, larger dogs require paid ticket
Quiet zone
Complete guide to Domodossola
Things to do in Domodossola
Discover the best of Domodossola — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Domodossola trip today.
- Recommended
Casa De Rodis
Prestigious exhibition venue hosting major temporary shows in a restored palace, a key destination for art lovers in Ossola.
- Recommended
Museo del Sacro Monte Calvario
Museum route at the sacred mount interpreting chapels, devotion, and local religious heritage in a UNESCO setting.
- Must visit
Piazza del Mercato
Domodossola's arcaded medieval market square, lively and photogenic, ideal for architecture, atmosphere, and people-watching.
- Must visit
Centro Storico di Domodossola
Historic old town lanes with arcades and stone houses, best explored on foot for local character and hidden details.
- Must visit
Percorso del Sacro Monte Calvario
Scenic pilgrimage path climbing to the sacred mount, combining chapels, woodland, and rewarding panoramic viewpoints.
- Gluten-free
Polenta Ossolana
Hearty mountain polenta from Ossola, often served with cheese, butter, sausage, or game. It is a staple of local Alpine cooking and cold-weather meals.
- Vegetarian
- Gluten-free
Risotto Al Vino Rosso
Rich risotto made with local red wine from nearby northern Piedmont. It reflects the region's rice culture and love of robust mountain flavors.
- Gluten-free
Prosciutto Crudo D'Ossola
Air-dried cured ham from the Ossola valleys, prized for its delicate alpine flavor. It is a classic local salumi served as an antipasto.
Atelier Restaurant & Bistrot
Refined dining venue focused on Piedmont and mountain cuisine, with careful presentation and a more elegant setting.
Ristorante La Meridiana
Historic, traditional restaurant in Domodossola known for Ossola specialties, local wines, and a warm alpine atmosphere.
Ristorante Pizzeria Vecchio Borgo
Casual and popular spot for pizza and Italian classics, suitable for relaxed meals in the town center.
Euro (€)
Moderate for northern Italy. Meals and hotels are usually cheaper than Milan or Lake Como, while local transit and coffee stay fairly reasonable for tourists.
Average meal costs
- Budget
- €8-12 for pizza slices, panini, or simple lunches.
- Mid-range
- €18-30 per person for a restaurant meal.
- Fine dining
- €50+ per person for upscale dining.
- Coffee
- €1.20-2.50 for espresso or cappuccino.
Tipping culture
Service is often included or covered by coperto. Rounding up or leaving €1-2 at cafes is enough; 5-10% in restaurants is optional for great service. Taxis usually get the fare rounded up.
MooneyGo
Get the appOfficial public transport app
Prices
- Single ticket
- €1.50
- Day pass
- : null
To the city center
Domodossola Railway Station -> Piazza del Mercato, Domodossola
- Distance
- 700 m
- Travel time
- 10 min
- Buy local bus tickets before boarding; onboard sales may be limited or unavailable.
- Contactless payment on Domodossola local buses is not reliably confirmed, so carry a valid paper or mobile ticket before travel.
FAQs: Trains from Florence Santa Maria Novella to Domodossola
Find answers to the most common questions about traveling from Florence Santa Maria Novella to Domodossola by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Domodossola, this guide helps you travel smarter and with confidence.
Train ticket prices from Florence Santa Maria Novella to Domodossola can vary. The cheapest ticket starts at $42, while the average price is around $76.
The train from Florence Santa Maria Novella to Domodossola takes 3h 34m and runs 8 per day.
The first train from Florence Santa Maria Novella to Domodossola leaves at 2:30 AM.
The distance by train from Florence Santa Maria Novella to Domodossola is 216 miles (349 km).
The last train from Florence Santa Maria Novella to Domodossola leaves at 6:21 AM.
Yes, there is a high-speed train from Florence Santa Maria Novella to Domodossola.
There is no direct train service currently available from Florence Santa Maria Novella to Domodossola.
Unfortunately, there is no night train available from Florence Santa Maria Novella to Domodossola.
The cheapest way to get from Florence Santa Maria Novella to Domodossola is by train, with a cost of around $42.
The train journey from Firenze Santa Maria Novella to Domodossola offers scenic views, particularly as you travel through the rolling hills of Tuscany and the picturesque landscape of the Italian countryside, passing through charming towns and stunning natural vistas.
A day trip from Firenze Santa Maria Novella to Domodossola is not feasible as the travel duration is 3h 34m. However, there are 11 trains available per day for this journey, covering a distance of 216 miles (349 km).
In Domodossola, visitors can enjoy skiing and snowboarding at the Domobianca Ski Resort during winter. The town offers a rich cultural experience with guided tours of the historic town center and exploration of local markets and shops for unique Italian goods. Notable sights include the Piazza del Mercato, Sacro Monte Calvario, Palazzo Silva, and the Collegiate Church of Saints Gervasius and Protasius. Nature enthusiasts can hike in the surrounding mountains and the Val Grande National Park. Additionally, visiting local wineries provides an opportunity to taste regional wines and learn about winemaking.
A stay of 2 to 3 days in Domodossola is ideal to explore its historic town center, enjoy the local cuisine, and take day trips to nearby attractions such as the Sacro Monte Calvario and the scenic routes of the Ossola Valley.
Yes, you can take the train from Florence Santa Maria Novella to Domodossola.
Since both Florence Santa Maria Novella and Domodossola are in the Schengen Area, a passport is not required for European Union (EU) or Schengen-associated country citizens. A national ID card is sufficient.
Popular day trips by train from Domodossola include Milan, Zermatt, Brig-Glis, Stresa, Interlaken.
We recommend using the flight as it is the most popular way to get from Florence Santa Maria Novella to Domodossola among Omio's users.
Items not allowed on trains typically include hazardous materials such as explosives, flammable liquids, corrosive substances, and illegal drugs. Additionally, large or bulky items that may obstruct aisles or emergency exits, as well as pets without proper carriers, may be restricted. Specific prohibited items can vary by train operator and region, so please check the rules for your particular journey.
Yes, rail passes such as the Eurail Italy Pass and Interrail Italy Pass are valid on most trains operated by Trenitalia and Italo within Italy, including regional, intercity, and high-speed trains, though some restrictions and seat reservation fees may apply.
Italy uses the euro (EUR) as its currency. Travelers generally find it convenient to use cards for most payments, especially in cities and larger establishments, but carrying some cash is advisable for small shops, markets, and rural areas where card acceptance may be limited.
In Domodossola, travelers should be mindful of typical urban safety concerns such as pickpocketing, especially in crowded areas like markets and train stations. It is advisable to keep personal belongings secure and avoid displaying valuables openly. Scams are relatively rare, but travelers should be cautious of unofficial taxi drivers or overly persistent street vendors. Staying aware of surroundings and using licensed services helps ensure a safe visit.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular train stations
Popular train stations from Florence Santa Maria Novella to Domodossola
Most Florence Santa Maria Novella to Domodossola trains use the Firenze Santa Maria Novella to Domodossola station pair. Use this guide to compare Florence Santa Maria Novella and Domodossola train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Departure train stations in Florence
Arrival train stations in Domodossola
Firenze Santa Maria NovellaPiazza della Stazione, 1, 50123 Florence, Italy+39 0552352595
City-centre transport
Getting to Firenze Santa Maria Novella from Florence city centre
Firenze Santa Maria Novella is 1 km from Florence city centre. Public transport options include:
TramT2 · 4m · $2 · every ~21 min
Firenze Santa Maria Novella train station facilities and services
Firenze Santa Maria Novella has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Ticket Office, Bike Parking, Bike Rental, Car Rental, and Information Desk.
Food and drink
Food options include: 12oz Coffee Joint, Casa Maioli, Don Nino, Fratelli Cuore, McDonald´s, Panella, Segafredo Zanetti, Spizzico, Venchi, & many more
Wi-Fi and ATMs
Free WiFi (30 minutes limit). ATMs are located in the basement in the shopping center next to the Feltrinelli bookshop and between Celio and Mango shops.
Tickets and information
The ticket office is open Mon - Sun: 06:00 - 21:00. Information desks are located inside and outside the station.
Luggage and lost property
Luggage storage is provided by KiPoint and located on the ground floor, on the side of Piazza Adua. Open daily from 06:00 to 23:00.
Parking, taxis and toilets
Available at Firenze Santa Maria Novella: Parking, Taxis, WC.
Bike and car services
Available at Firenze Santa Maria Novella: Bike Parking, Bike Rental, Car Rental.
Accessibility
Accessibility facilities are available at Firenze Santa Maria Novella: Elevators, escalators, step-free access. Mobility assistance is available with the Sala Blu, located next to Platform 1.
Shops, hotels and contact
Nearby hotels include Hotel Luxor Florence, Joy Hotel Florence, Diplomat Hotel Florence.
DomodossolaPiazza Matteotti, 28845 Domodossola VB, Italy+39 0324 242 113
City-centre transport
Getting to Domodossola from Domodossola city centre
TrainRegional and Eurocity trains
BusSeveral local lines available
Domodossola train station facilities and services
Domodossola has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Car Rental, Information Desk, and Luggage Carts.
Food and drink
Food options include: Ristorante La Meridiana, Osteria Vecchio Borgo
Wi-Fi and ATMs
Free. ATMs are available in the train station.
Tickets and information
Ticket office support is available at Domodossola. Information desks are located in the main hall.
Luggage and lost property
Luggage storage is available at Domodossola. Lost and found is available at the station.
Parking, taxis and toilets
Available at Domodossola: Parking, Taxis, WC.
Bike and car services
Available at Domodossola: Bike Parking, Car Rental.
Accessibility
Accessibility facilities are available at Domodossola: Elevators, ramps.
Shops, hotels and contact
Nearby hotels include Hotel Corona, Hotel Ristorante Eurossola, Hotel Domodossola.
Most popular train connections from Florence Santa Maria Novella
More options for your journey from Florence Santa Maria Novella to Domodossola
Here are some other resources that might have the information you need
Most popular trains to and from Domodossola and Florence Santa Maria Novella
Most popular train connections to Domodossola
HomeTrainsTrains in ItalyTrain Times to DomodossolaFlorence Santa Maria Novella to Domodossola train
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