The cheapest and fastest trains from Florence Santa Maria Novella to Domodossola
Cheapest price
$48
Average price
$79
Fastest journey
3 h 54 m
Average duration
4 h 19 m
Trains per day
11
Distance
349 km
The best way to find a cheap train ticket from Florence Santa Maria Novella to Domodossola is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Florence Santa Maria Novella to Domodossola will cost around $79 if you buy it on the day, but the cheapest tickets can be found for only $48.
It's difficult to get from Florence Santa Maria Novella to Domodossola without transferring at least once.
Regionale 18253 · Regionale 2594 · Regionale 10228
Regionale 18373+
Intercity 680+
Regionale TRENORD 2442
Tuscany Line 4013+
Intercity 666+
Regionale TRENORD 2428
TUSCANY LINE 4029+
Intercity 674+
Regionale TRENORD 2436
TUSCANY LINE 4021+
Intercity 670+
Regionale TRENORD 2432
FRECCIAROSSA 9310+
Regionale TRENORD 2428
FRECCIAROSSA 9552+
Regionale TRENORD 2442
FRECCIAROSSA 9532+
Regionale TRENORD 2432
FRECCIAROSSA 1000 9308+
Regionale TRENORD 2426 · Autobus TRENORD 2426A
FRECCIAROSSA 1000 9308+
Regionale 10228Travel Information
Compare train, bus, and flight for Florence Santa Maria Novella to Domodossola
Omio recommends booking the train as it is the most popular option from Florence Santa Maria Novella to Domodossola among Omio's users. If you are prioritising price take the train with prices starting from €29. For those with little time consider booking a bus which can get you there in 4h 15m. The ticket price range depends on the travel mode: a train costs an average of €29, and a flight costs an average of €115.
Distance: 216 miles (349 km)
Compare train with
Most popular Train | Bus | Flight |
|---|---|---|
€41 Average price Cheapest | €72 Average price | €153 Average price |
5h 0m Average total duration 4h 30m Onboard + 30m Additional time* | 4h 45m Average total duration Fastest 4h 15m Onboard + 30m Additional time* | 10h 12m Average total duration 7h 12m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
Live departures
Florence Santa Maria Novella to Domodossola train times
The table below shows live departures for Florence Santa Maria Novella to Domodossola trains for tomorrow, Friday, November 7. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
Regionale 18253 · Regionale 2594 · Regionale 10228 | 3:30 AM Florence Santa Maria Novella | 11h23 | 2:53 PM Domodossola station | 2 transfers | |
Tuscany Line 4013+ Intercity 666+ Regionale TRENORD 2428 | 6:28 AM Florence Santa Maria Novella | 8h36 | 3:04 PM Domodossola station | 2 transfers | |
FRECCIAROSSA 9516+ Regionale Veloce 2024 · Regionale 11428 | 8:55 AM Florence Santa Maria Novella | 5h47 | 2:42 PM Domodossola station | 2 transfers | |
TUSCANY LINE 4021+ Intercity 670+ Regionale TRENORD 2432 | On time 9:28 AM Florence Santa Maria Novella | 7h36 | 5:04 PM Domodossola station | 2 transfers | |
FRECCIAROSSA 1000 9308+ Regionale 10228 | 10:10 AM Florence Santa Maria Novella | 4h43 | 2:53 PM Domodossola station | 1 transfer | |
FRECCIAROSSA 1000 9308+ Regionale TRENORD 2426 · Autobus TRENORD 2426A | 10:10 AM Florence Santa Maria Novella | 4h40 | 2:50 PM Domodossola station | 2 transfers | |
FRECCIAROSSA 9310+ Regionale TRENORD 2428 | 11:10 AM Florence Santa Maria Novella | 3h54 | 3:04 PM Domodossola station | 1 transfer | |
TUSCANY LINE 4029+ Intercity 674+ Regionale TRENORD 2436 | 11:28 AM Florence Santa Maria Novella | 7h36 | 7:04 PM Domodossola station | 2 transfers | |
Regionale 18373+ Intercity 680+ Regionale TRENORD 2442 | 12:53 PM Florence Santa Maria Novella | 9h11 | 10:04 PM Domodossola station | 2 transfers | |
FRECCIAROSSA 9532+ Regionale TRENORD 2432 | 12:55 PM Florence Santa Maria Novella | 4h09 | 5:04 PM Domodossola station | 1 transfer | |
Find all the dates and times for this journey
Compare prices and tickets Florence Santa Maria Novella to Domodossola by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Nov 07
Nov 08
Nov 09
Nov 10
Nov 11
Nov 12
Nov 13
Journey information
Overview: Train from Florence Santa Maria Novella to Domodossola
Distance 216 miles (349 km) |
Average train duration 4h 30m |
Cheapest ticket price $36 (€29) |
Trains per day 11 |
Fastest train 3h 54m |
First train 02:30 |
Last train 15:10 |
Key Takeaways
Train Ticket Prices
- Budget Options: Train tickets from Florence Santa Maria Novella to Domodossola start from as low as $36 (€29) if booked well in advance.
- Standard Fares: Typically, trains cost $51 (€41) depending on the train type and class.
Train companies: Frecciarossa, Italo, Regionale, Intercity from Florence Santa Maria Novella to Domodossola trainsFrecciarossa, Italo, Regionale, Intercity trains will get you between Florence Santa Maria Novella and Domodossola from $36 (€29). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Frecciarossa
Italo
Regionale
Intercity
FAQs: Trains from Florence Santa Maria Novella to Domodossola
Find answers to the most common questions about traveling from Florence Santa Maria Novella to Domodossola by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Domodossola, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Florence Santa Maria Novella to Domodossola
- Mon - Sun: 06:00 - 21:00
- Free WiFi (30 minutes limit).
- Provided by KiPoint and located on the ground floor, on the side of Piazza Adua. Open daily from 06:00 to 23:00.
- 12oz Coffee Joint
- Casa Maioli
- Don Nino
- Fratelli Cuore
- McDonald´s
- Panella
- Segafredo Zanetti
- Spizzico
- Venchi
- & many more
- Elevators, escalators, step-free access. Mobility assistance is available with the Sala Blu, located next to Platform 1.
- Hotel Luxor Florence
- Joy Hotel Florence
- Diplomat Hotel Florence
- Mon - Sun: 06:00 - 21:00
- Located inside and outside the station.
- Tram lines: T1, T2
- Bus lines: 6, 11, 12, 13, 17, 23, 36, 37, C4
- Train lines: FR, FA, Italo
- 6:00 AM - 8:00 PM Monday - Sunday
- Free
- The car park is open 7 days a week, accessible from the main entrance.
- Ristorante La Meridiana
- Osteria Vecchio Borgo
- Outside the main entrance.
- Elevators, ramps.
- €1
- Hotel Corona
- Hotel Ristorante Eurossola
- Hotel Domodossola
- Located in the main hall
- Avis
- Europcar
- Located in the main hall
- Free
- Hall 1: main entrance, platform 1-5 for trains to Switzerland and regional destinations
- Train: Regional and Eurocity trains
- Bus: Several local lines available
Most popular train connections from Florence Santa Maria Novella
More options for your journey from Florence Santa Maria Novella to Domodossola
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