- Must visit
Antonino Salinas Regional Archaeological Museum
Palermo’s top museum displays Sicilian archaeology, including the famous Punic Stone and Selinunte finds, in a former convent complex.
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The cheapest and fastest trains from Florence Santa Maria Novella to Palermo
Showing times, prices and bookable tickets for Sep 18
Cheapest price on Sep 18
€120
Average ticket price on Sep 18
€137
Fastest journey on Sep 18
12 h 44 m
Average journey duration on Sep 18
13 h 58 m
Trains on Sep 18
7
Distance
654 km
Cheap tickets
The best way to find a cheap train ticket from Florence Santa Maria Novella to Palermo is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Florence Santa Maria Novella to Palermo will cost around €137 if you buy it on the day, but the cheapest tickets can be found for only €120.
Fast trains
It's difficult to get from Florence Santa Maria Novella to Palermo without transferring at least once.
Regionale 18251+
InterCityNotte 899+
Intercity 72312:40 AM18h24Florence Santa Maria Novella7:04 PMPalermo Centrale€1201One-way2 transfers- Intercity 581 · Intercity 551 · Intercity 7275:45 AM17h13Florence Santa Maria Novella10:58 PMPalermo Centrale€1321One-way2 transfers
FRECCIAROSSA 9519+Intercity 72710:14 AM12h44Florence Santa Maria Novella10:58 PMPalermo Centrale€1401One-way1 transfer- FRECCIAROSSA 9503+Intercity 7236:00 AM13h04Florence Santa Maria Novella7:04 PMPalermo Centrale€1401One-way1 transfer
- FRECCIAROSSA 9551+InterCityNotte 19556:14 PM14h59Florence Santa Maria Novella9:13 AMPalermo Centrale€1421One-way1 transfer
- FRECCIAROSSA 9519+Intercity 72710:14 AM12h44Florence Santa Maria Novella10:58 PMPalermo Centrale€1401One-way1 transfer
- FRECCIAROSSA 9503+Intercity 7236:00 AM13h04Florence Santa Maria Novella7:04 PMPalermo Centrale€1401One-way1 transfer
- FRECCIAROSSA 9555 · FRECCIAROSSA 9653+InterCityNotte 19557:14 PM13h59Florence Santa Maria Novella9:13 AMPalermo Centrale€1471One-way2 transfers
- FRECCIAROSSA 9551+InterCityNotte 19556:14 PM14h59Florence Santa Maria Novella9:13 AMPalermo Centrale€1421One-way1 transfer
- FRECCIAROSSA 9437+InterCityNotte 19599:48 PM15h02Florence Santa Maria Novella12:50 PMPalermo Centrale€1421One-way1 transfer
Travel Information
Compare train, bus, flight, and ferry for Florence Santa Maria Novella to Palermo
Omio recommends booking the flight as it is the most popular option from Florence Santa Maria Novella to Palermo among Omio's users. If you are prioritising price, take the ferry, with an average ticket price of €49 For those with little time, consider booking a flight, which has an average total journey time of 4h 44m. Average ticket prices depend on the travel mode: a ferry costs an average of €49, while a flight costs an average of €235.
Distance: 406 miles (654 km)
Compare train with
| Train | Most popular Flight | Bus | Ferry | Driving |
|---|---|---|---|---|
€120 Average price | €235 Average price | €96 Average price | €49 Average price Cheapest | €68 Average price (fuel + tolls) |
15h 7m Average total duration 14h 37m Onboard + 30m Additional time* | 4h 44m Average total duration Fastest 2h 44m Onboard + 2h 0m Additional time* | 21h 4m Average total duration 20h 34m Onboard + 30m Additional time* | 20h 35m Average total duration 19h 35m Onboard + 1h 0m Additional time* | 24h 9m Average total duration (door-to-door) |
Most popular train company |  Most popular airline |  Most popular bus company |  Most popular ferry company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options | Direct Options |
The cheapest way to travel from Florence Santa Maria Novella to Palermo is a ferry with an average price of €49.
This is compared to other travel options from Florence Santa Maria Novella to Palermo:
A ferry is €47 less than a bus for this route with tickets for a bus from Florence Santa Maria Novella to Palermo costing on average €96.
A ferry is €71 less than a train for this route with tickets for a train from Florence Santa Maria Novella to Palermo costing on average €120.
A ferry is €186 less than a flight for this route with tickets for a flight from Florence Santa Maria Novella to Palermo costing on average €235.
The fastest way to travel from Florence Santa Maria Novella to Palermo is by flight with an average journey time of 2h 44m.
Other travel options to Palermo take longer:
Train takes on average 14h 37m.
Ferry takes on average 19h 35m.
Bus takes on average 20h 34m.
It's helpful to compare your options as there are 4 ways to travel between Florence Santa Maria Novella and Palermo including taking a train, bus, flight, and ferry.
We recommend using the train as it is the most popular way to get from Florence Santa Maria Novella to Palermo among Omio's users.
Take the train. It's meaningfully faster than driving, and the time saved usually justifies the price.
You'll arrive about 9h 32m sooner (14h 37m by train vs 24h 9m by car). Tickets start at around €120 compared to roughly €68 in fuel and tolls — so you're paying a bit more, but getting hours of your day back, a city-centre arrival, and the freedom to work or relax instead of drive.
Driving makes more sense if you're travelling as a group (where fuel costs split several ways), want to stop along the way, or need a car once you arrive.
Live departures
Florence Santa Maria Novella to Palermo train times
The table below shows live departures for Florence Santa Maria Novella to Palermo trains for today, Thursday, September 17. You can also manually refresh the results below to see updated train journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| FRECCIAROSSA 9437+InterCityNotte 1959 | 9:48 PM Florence Santa Maria Novella | 15h02 | 12:50 PM Palermo Centrale | 1 transfer | |
| Friday, September 18 | |||||
| Regionale 18251+InterCityNotte 899+Intercity 723 | 12:40 AM Florence Santa Maria Novella | 18h24 | 7:04 PM Palermo Centrale | 2 transfers | |
| Intercity 581 · Intercity 551 · Intercity 727 | 5:45 AM Florence Santa Maria Novella | 17h13 | 10:58 PM Palermo Centrale | 2 transfers | |
| FRECCIAROSSA 9503+Intercity 723 | 6:00 AM Florence Santa Maria Novella | 13h04 | 7:04 PM Palermo Centrale | 1 transfer | |
| FRECCIAROSSA 9519+Intercity 727 | 10:14 AM Florence Santa Maria Novella | 12h44 | 10:58 PM Palermo Centrale | 1 transfer | |
| FRECCIAROSSA 9551+InterCityNotte 1955 | 6:14 PM Florence Santa Maria Novella | 14h59 | 9:13 AM Palermo Centrale | 1 transfer | |
| FRECCIAROSSA 9555 · FRECCIAROSSA 9653+InterCityNotte 1955 | 7:14 PM Florence Santa Maria Novella | 13h59 | 9:13 AM Palermo Centrale | 2 transfers | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Florence Santa Maria Novella to Palermo by train, bus, flight, or ferry
Compare train, bus, flight, and ferry prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Florence Santa Maria Novella to Palermo trains with Omio?
Intercity Notte as well as Intercity, Frecciarossa, Italo and more offer trains services from Florence Santa Maria Novella to Palermo.
Omio is the only official third party seller for Intercity Notte tickets.
Why book with Omio vs Intercity Notte?
- Compare with other providers: On Omio, you can not only buy tickets for Intercity Notte, but also compare tickets for the likes of Intercity, Frecciarossa or Italo to find the best option for your trip from Florence Santa Maria Novella to Palermo.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Intercity Notte with all available travel options, which are train, bus, flight and ferry to ensure you get the best deal for traveling from Florence Santa Maria Novella to Palermo.
Journey information
Overview: Train from Florence Santa Maria Novella to Palermo
ItalyItaly
Trains from Florence Santa Maria Novella to Palermo run on average 6 times per day, taking around 14h 37m. Cheap train tickets for this journey start at €79 but you can travel from only €19 by flight.
The earliest train runs at 01:13, the last at 22:40. The fastest train covers the 406 miles (654 km) distance in 11h 50m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from €19
Distance 406 miles (654 km) |
Average train duration 14h 37m |
Cheapest ticket price €79 |
Trains per day 6 |
Fastest train 11h 50m |
First train 1:13 AM |
Last train 10:40 PM |
Cheapest Month Nov |
Cheapest Day Wed |
High Season Apr - Jun |
Low Season Jan - Mar |
Busiest Day Tue |
Least Busy Day Wed |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from €19
Train companies: Intercity, Intercity Notte from Florence Santa Maria Novella to Palermo trainsIntercity, Intercity Notte trains will get you between Florence Santa Maria Novella and Palermo from €19. With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Intercity
About
Trenitalia Intercity is a high-speed train service operated by the Italian national railway company, Trenitalia. It operates throughout the country, with services running from early morning to late evening. The Intercity trains come in two types: the Intercity Plus, which is the fastest and most comfortable, and the Intercity, which is slightly slower but still offers a comfortable journey. Onboard facilities include air conditioning, power sockets, Wi-Fi, and a bar service. There are several ticket types available, including Standard, Super Economy, and Business. The most popular routes for Trenitalia Intercity are from Rome to Milan, Naples to Florence, and Turin to Venice.
Luggage & cancellation policy
Average Intercity Duration
11h 50m
Cheapest Intercity Price
€80
Intercity frequency
3 a day
Luggage included
2 pieces of luggage up to 30kg total
Luggage storage
Overhead racks and designated luggage areas at end of carriages
Cancellation Policy
According to ticket conditions
Refund
Full refund provided
Amenities on board the train
Wifi
Food sold onboard
Restaurant car with hot meals and snacks, trolley service in some trains. But do not count on the presence of a buffet car. So if having access to food and drink on the train is important to you, it’s best to bring your own refreshments onboard.
Seat reservation
Seat reservation included in ticket price for most routes
Toilets
USB plugs
Accessibility
Wheelchair spaces and accessible toilets available
Pets
Small pets in carriers allowed free, larger dogs require paid ticket
Quiet zone
Intercity Notte
About
Intercity Notte is an Italian train service operated by Trenitalia. It runs overnight services between major cities in Italy, making it a great option for travelers looking to save time and money. The Intercity Notte offers two types of trains: the Frecciarossa Notte and the Frecciargento Notte. The Frecciarossa Notte is the fastest train, with speeds of up to 300 km/h, while the Frecciargento Notte is slightly slower but still offers a comfortable journey. Both trains offer a range of onboard facilities, including comfortable seating, air conditioning, and Wi-Fi. Trenitalia offers a range of ticket types, including Standard, Comfort, and Business. Standard tickets are the most affordable, while Comfort and Business tickets offer additional benefits such as priority boarding and access to the lounge. The most popular routes for Intercity Notte are Rome to Milan, Rome to Venice, and Milan to Venice. These routes offer travelers the chance to explore some of Italy's most iconic cities in a convenient and comfortable way.
Luggage & cancellation policy
Average Intercity Notte Duration
13h 12m
Cheapest Intercity Notte Price
€79
Intercity Notte frequency
3 a day
Luggage included
1 handbag and 1 suitcase included in ticket price
Luggage storage
Luggage racks above seats and at carriage ends
Cancellation Policy
Cancellation possible according to ticket type conditions
Refund
Full refund provided for canceled trains
Amenities on board the train
Wifi
Food sold onboard
Restaurant car with full dining service and bar
Seat reservation
Seat reservation included in ticket price
Toilets
USB plugs
Accessibility
Wheelchair spaces and assistance available for disabled passengers
Pets
Small pets in carriers travel free. Larger dogs require paid ticket and muzzle. Guide dogs free.
Quiet zone
Complete guide to Palermo
Things to do in Palermo
Discover the best of Palermo — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Palermo trip today.
- Recommended
Palazzo Mirto
Historic rooms and vivid majolica floors showcase aristocratic Palermo. Visit for decorative arts, period interiors and city history.
- Recommended
Steri Museum
Housed in the grand Steri Palace, this museum presents the Sicilian Inquisition’s story through cells, graffiti and historical documents.
- Must visit
Via Vittorio Emanuele
Palermo’s elegant main boulevard links major monuments, shops and theaters. Ideal for first walks and observing the city’s layered architecture.
- Must visit
Via Maqueda
This historic street cuts across the old center and hosts markets, churches and daily life. A lively route for exploring local Palermo.
- Recommended
Albergheria
A bustling old quarter famous for layered street life, churches and market culture. Best explored on foot for atmosphere and urban history.
Arancina
Crisp fried rice ball stuffed with ragù, peas and caciocavallo. A Sicilian street food icon widely loved in Palermo.
Pane con la Milza
Soft sesame-topped bun filled with spleen and lung, often with caciocavallo or ricotta. A classic Palermo street food with deep local roots.
Pasta con le Sarde
Pasta with sardines, wild fennel, pine nuts and raisins. Its sweet-savory flavor reflects Palermo's Arab-Norman culinary heritage.
I Pupi
Refined Michelin-starred restaurant known for creative Sicilian tasting menus in an elegant, intimate setting.
Osteria Ballarò
Historic seafood restaurant near the port, praised for fresh catch, raw dishes and classic Palermo fish recipes.
Nni Franco U Vastiddaru
Legendary no-frills street-food stop celebrated for pane con la milza and authentic local sandwiches loved by residents.
Euro (€)
Moderate for Italy. Street food and local meals are affordable, while hotels in peak season cost more. Public transport is cheap, keeping overall tourist costs reasonable.
Average meal costs
- Budget
- €8-12 for street food or a simple meal.
- Mid-range
- €20-35 per person for a restaurant meal.
- Fine dining
- €60+ per person for upscale dining.
- Coffee
- €1.50-3 for coffee or cappuccino.
Tipping culture
Service is often included or modest. Round up or leave 5-10% for great restaurant service. Taxis are usually rounded up. Small change is fine in cafes.
Palermo AMAT
Get the appOfficial public transport app
Prices
- Single ticket
- €1.40
- Day pass
- €5.50
To the city center
Palermo Centrale -> Quattro Canti, Palermo
- Distance
- 1.4 km
- Travel time
- 20 min
- Validate paper tickets when boarding; inspectors check on buses and trams.
- AMAT buses and trams generally support contactless bank card payment onboard, but carry a backup ticket in case the validator is unavailable.
FAQs: Trains from Florence Santa Maria Novella to Palermo
Find answers to the most common questions about traveling from Florence Santa Maria Novella to Palermo by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Palermo, this guide helps you travel smarter and with confidence.
Train ticket prices from Florence Santa Maria Novella to Palermo can vary. The cheapest ticket starts at €79, while the average price is around €120.
The train from Florence Santa Maria Novella to Palermo takes 11h 50m and runs 6 per day.
The first train from Florence Santa Maria Novella to Palermo leaves at 1:13 AM.
The distance by train from Florence Santa Maria Novella to Palermo is 406 miles (654 km).
The last train from Florence Santa Maria Novella to Palermo leaves at 10:40 PM.
There is no high speed train available from Florence Santa Maria Novella to Palermo.
There is no direct train service currently available from Florence Santa Maria Novella to Palermo.
Yes, there is a night train from Florence Santa Maria Novella to Palermo.
The cheapest way to get from Florence Santa Maria Novella to Palermo is by flight, with a cost of around €19.
Yes, the train journey from Firenze Santa Maria Novella to Palermo is scenic, offering views of Tuscany's rolling hills, the picturesque coastline along the Tyrrhenian Sea, and the dramatic landscapes of Sicily.
A day trip from Firenze Santa Maria Novella to Palermo is not feasible as the journey takes 11h 50m and covers a distance of 406 miles (654 km). Trains run 6 times per day.
In Palermo, you can explore the Capuchin Catacombs, visit the bustling Ballarò Market, and admire vibrant street art in the Vucciria district. Take a cooking class to learn traditional Sicilian dishes or enjoy a stroll along the Foro Italico promenade. Don't miss the Palermo Cathedral, Teatro Massimo, Palazzo dei Normanni with the Palatine Chapel, Quattro Canti, and the lush Orto Botanico di Palermo.
Typically, spending 3 to 4 days in Palermo allows you to explore its main attractions, enjoy local cuisine, and immerse yourself in the city's vibrant culture.
Yes, you can take the train from Florence Santa Maria Novella to Palermo.
Since both Florence Santa Maria Novella and Palermo are in the Schengen Area, a passport is not required for European Union (EU) or Schengen-associated country citizens. A national ID card is sufficient.
Popular day trips by train from Palermo include Cefalù, Punta Raisi, Bagheria, Santa Flavia, Capo d'Orlando.
We recommend using the flight as it is the most popular way to get from Florence Santa Maria Novella to Palermo among Omio's users.
Items not allowed on trains typically include hazardous materials such as explosives, flammable liquids, corrosive substances, and illegal drugs. Additionally, large or bulky items that may obstruct aisles or emergency exits, as well as pets without proper carriers, may be restricted. Specific prohibited items can vary by train operator and region, so please check the rules for your particular journey.
Yes, rail passes such as the Eurail Italy Pass and Interrail Italy Pass are valid on most trains operated by Trenitalia and Italo within Italy, including regional, intercity, and high-speed trains, though some restrictions and seat reservation fees may apply.
Italy uses the euro (EUR) as its currency. Travelers generally find it convenient to use cards for most payments, especially in cities and larger establishments, but carrying some cash is advisable for small shops, markets, and rural areas where card acceptance may be limited.
In Palermo, travelers should be cautious of petty theft, especially pickpocketing in crowded areas like markets and public transport. Scams include overcharging by taxi drivers and vendors, as well as unofficial guides offering overpriced tours. It's advisable to use authorized services and stay vigilant in busy tourist spots.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular train stations
Popular train stations from Florence Santa Maria Novella to Palermo
Most Florence Santa Maria Novella to Palermo trains use the Firenze Santa Maria Novella to Palermo Centrale station pair. Use this guide to compare Florence Santa Maria Novella and Palermo train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Departure train stations in Florence
Arrival train stations in Palermo
Firenze Santa Maria NovellaPiazza della Stazione, 1, 50123 Florence, Italy+39 0552352595
City-centre transport
Getting to Firenze Santa Maria Novella from Florence city centre
Firenze Santa Maria Novella is 1 km from Florence city centre. Public transport options include:
TramT2 · 4m · €2 · every ~21 min
Firenze Santa Maria Novella train station facilities and services
Firenze Santa Maria Novella has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Ticket Office, Bike Parking, Bike Rental, Car Rental, and Information Desk.
Food and drink
Food options include: 12oz Coffee Joint, Casa Maioli, Don Nino, Fratelli Cuore, McDonald´s, Panella, Segafredo Zanetti, Spizzico, Venchi, & many more
Wi-Fi and ATMs
Free WiFi (30 minutes limit). ATMs are located in the basement in the shopping center next to the Feltrinelli bookshop and between Celio and Mango shops.
Tickets and information
The ticket office is open Mon - Sun: 06:00 - 21:00. Information desks are located inside and outside the station.
Luggage and lost property
Luggage storage is provided by KiPoint and located on the ground floor, on the side of Piazza Adua. Open daily from 06:00 to 23:00.
Parking, taxis and toilets
Available at Firenze Santa Maria Novella: Parking, Taxis, WC.
Bike and car services
Available at Firenze Santa Maria Novella: Bike Parking, Bike Rental, Car Rental.
Accessibility
Accessibility facilities are available at Firenze Santa Maria Novella: Elevators, escalators, step-free access. Mobility assistance is available with the Sala Blu, located next to Platform 1.
Shops, hotels and contact
Nearby hotels include Hotel Luxor Florence, Joy Hotel Florence, Diplomat Hotel Florence.
Most popular train connections from Florence Santa Maria Novella
More options for your journey from Florence Santa Maria Novella to Palermo
Here are some other resources that might have the information you need
Most popular trains to and from Palermo and Florence Santa Maria Novella
Most popular train connections to Palermo
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