The cheapest and fastest trains from Florence Santa Maria Novella to Palermo
Cheapest price
$113
Average price
$133
Fastest journey
14 h 8 m
Average duration
15 h 14 m
Trains per day
2
Distance
654 km
The best way to find a cheap train ticket from Florence Santa Maria Novella to Palermo is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Florence Santa Maria Novella to Palermo will cost around $133 if you buy it on the day, but the cheapest tickets can be found for only $113.
Of the 2 trains that leave Florence Santa Maria Novella for Palermo on Fri, Nov 07, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Fri, Nov 07 the direct trains cover the 654 km distance in an average of 15 h 14 m but if you time it right, some trains will get you there in just 14 h 8 m .
On Fri, Nov 07 the slowest trains will take 16 h 20 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.




Travel Information
Compare train, bus, flight, and ferry for Florence Santa Maria Novella to Palermo
Omio recommends booking the train as it is the most popular option from Florence Santa Maria Novella to Palermo among Omio's users. If you are prioritising price take the ferry with prices starting from €37. For those with little time consider booking a flight which can get you there in 1h 42m. The ticket price range depends on the travel mode: a ferry costs an average of €37, and a flight costs an average of €27.
Distance: 406 miles (654 km)
Compare train with
Most popular Train | Flight | Bus | Ferry |
|---|---|---|---|
€105 Average price | €134 Average price | €76 Average price | €55 Average price Cheapest |
13h 21m Average total duration 12h 51m Onboard + 30m Additional time* | 4h 42m Average total duration Fastest 1h 42m Onboard + 3h 0m Additional time* | 15h 40m Average total duration 15h 10m Onboard + 30m Additional time* | 20h 30m Average total duration 19h 30m Onboard + 1h 0m Additional time* |
![]() Most popular train company | ![]() Most popular airline | ![]() Most popular bus company | ![]() Most popular ferry company |
Direct Options | Direct Options | Direct Options | Direct Options |
Live departures
Florence Santa Maria Novella to Palermo train times
The table below shows live departures for Florence Santa Maria Novella to Palermo trains for tomorrow, Friday, November 7. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 4:35 AM Florence Santa Maria Novella | 16h20 | 8:55 PM Palermo | 0 transfersDirect | |
![]() | 9:24 PM Florence Santa Maria Novella | 14h08 | 11:32 AM Palermo | 0 transfersDirect | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Florence Santa Maria Novella to Palermo by train, bus, flight, or ferry
Compare train, bus, flight, and ferry prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Nov 07
Nov 08
Nov 09
Nov 10
Nov 11
Nov 12
Nov 13
Journey information
Overview: Train from Florence Santa Maria Novella to Palermo
Trains from Florence Santa Maria Novella to Palermo run on average 6 times per day, taking around 12h 51m. Cheap train tickets for this journey start at $82 (€67) but you can travel from only $33 (€27) by flight.
The earliest train runs at 03:35, the last at 21:26. The fastest train covers the 406 miles (654 km) distance in 12h 41m.
Distance 406 miles (654 km) |
Average train duration 12h 51m |
Cheapest ticket price $82 (€67) |
Trains per day 6 |
Fastest train 12h 41m |
First train 03:35 |
Last train 21:26 |
Train companies: Intercity Notte, Frecciarossa, Italo, Intercity, Frecciargento from Florence Santa Maria Novella to Palermo trainsIntercity Notte, Frecciarossa, Italo, Intercity, Frecciargento trains will get you between Florence Santa Maria Novella and Palermo from $33 (€27). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Intercity Notte
Frecciarossa
Italo
Intercity
Frecciargento
FAQs: Trains from Florence Santa Maria Novella to Palermo
Find answers to the most common questions about traveling from Florence Santa Maria Novella to Palermo by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Palermo, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Florence Santa Maria Novella to Palermo
- Mon - Sun: 06:00 - 21:00
- Free WiFi (30 minutes limit).
- Provided by KiPoint and located on the ground floor, on the side of Piazza Adua. Open daily from 06:00 to 23:00.
- 12oz Coffee Joint
- Casa Maioli
- Don Nino
- Fratelli Cuore
- McDonald´s
- Panella
- Segafredo Zanetti
- Spizzico
- Venchi
- & many more
- Elevators, escalators, step-free access. Mobility assistance is available with the Sala Blu, located next to Platform 1.
- Hotel Luxor Florence
- Joy Hotel Florence
- Diplomat Hotel Florence
- Mon - Sun: 06:00 - 21:00
- Located inside and outside the station.
- Tram lines: T1, T2
- Bus lines: 6, 11, 12, 13, 17, 23, 36, 37, C4
- Train lines: FR, FA, Italo
Most popular train connections from Florence Santa Maria Novella
More options for your journey from Florence Santa Maria Novella to Palermo
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