Travel Information
Compare bus, train, and flight for Harrisburg, PA to Durham, NC
Omio recommends booking the train as it is the most popular option from Harrisburg, PA to Durham, NC among Omio's users. If you are prioritising price take the bus with prices starting from $125. For those with little time consider booking a flight which can get you there in 5h 8m. The ticket price range depends on the travel mode: a bus costs an average of $125, and a flight costs an average of $359.
Distance: 315 miles (507 km)
Compare train with
Most popular Train | Flight | Bus |
|---|---|---|
$179 Average price | $390 Average price | $152 Average price Cheapest |
13h 23m Average total duration 12h 53m Onboard + 30m Additional time* | 8h 8m Average total duration Fastest 5h 8m Onboard + 3h 0m Additional time* | 17h 34m Average total duration 17h 4m Onboard + 30m Additional time* |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Harrisburg, PA to Durham, NC:
A bus is $27 (€22) less than a train for this route with tickets for a train from Harrisburg, PA to Durham, NC costing on average $179 (€145).
A bus is $238 (€192) less than a flight for this route with tickets for a flight from Harrisburg, PA to Durham, NC costing on average $390 (€315).
Other travel options to Durham, NC take longer:
Train takes on average 12h 53m.
Bus takes on average 17h 4m.
Compare prices and tickets Harrisburg, PA to Durham, NC by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Train from Harrisburg, PA to Durham, NC
Trains from Harrisburg, PA to Durham, NC run on average 1 times per day, taking around 12h 53m. Cheap train tickets for this journey start at $142 (€115) but you can travel from only $125 (€101) by bus.
The earliest train runs at 09:27, the last at 09:27. The fastest train covers the 315 miles (507 km) distance in 14h 0m.
Distance 315 miles (507 km) |
Average train duration 12h 53m |
Cheapest ticket price $142 (€115) |
Trains per day 1 |
Fastest train 14h 0m |
First train 9:27 AM |
Last train 9:27 AM |
Cheapest Month Mar |
Cheapest Day Wed |
High Season Jan - Mar |
Low Season Oct - Dec |
Busiest Day Wed |
Least Busy Day Wed |
Train companies: Amtrak from Harrisburg, PA to Durham, NC trainsAmtrak trains will get you between Harrisburg, PA and Durham, NC from $125 (€101). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Amtrak
FAQs: Trains from Harrisburg, PA to Durham, NC
Find answers to the most common questions about traveling from Harrisburg, PA to Durham, NC by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Durham, NC, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Harrisburg, PA to Durham, NC
- 6:00 AM - 10:00 PM Monday - Sunday
- Free
- Parking available on-site with both short-term and long-term options.
- The Millworks
- Bricco
- Outside the main entrance.
- Elevators, ramps, restrooms.
- $0.50
- Hilton Harrisburg
- Crowne Plaza Harrisburg-Hershey
- Radisson Hotel Harrisburg
- Located in the main hall
- Enterprise
- Hertz
- Located in the main hall
- Free
- Hall 1: main entrance, ticket office, and waiting area
- Hall 2: platforms for Amtrak and regional trains
- Hall 3: bus connections and car rental services
- Bus: CAT (Capital Area Transit) services available
- Greyhound and other intercity bus services
- 6:30 AM - 9:00 PM Monday - Sunday
- Free
- Parking is available nearby, with several public parking options in the vicinity.
- Parker and Otis
- Dame's Chicken & Waffles
- Outside the main entrance.
- Ramps.
- Free of charge
- Durham Marriott City Center
- 21c Museum Hotel Durham
- Aloft Durham Downtown
- Located in the main hall
- Located in the main hall
- Free
- Hall 1: main entrance, ticketing, and waiting area
- Hall 2: platform access
- Bus: GoDurham buses available
- Amtrak Thruway buses
Most popular train connections from Harrisburg, PA
More options for your journey from Harrisburg, PA to Durham, NC
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