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Travel Information
Compare train and bus for Sanford, FL to Florence, SC
Omio recommends booking the bus as it is the most popular option from Sanford, FL to Florence, SC among Omio's users. If you are prioritising price take the bus with prices starting from $133. For those with little time consider booking a train which can get you there in 12h 39m. The ticket price range depends on the travel mode: a bus costs an average of $133, and a train costs an average of $161.
Distance: 383 miles (617 km)
Compare train with
| Train | Most popular Bus |
|---|---|
$161 Average price | $133 Average price Cheapest |
13h 9m Average total duration Fastest 12h 39m Onboard + 30m Additional time* | 19h 43m Average total duration 19h 13m Onboard + 30m Additional time* |
Direct Options | Direct Options |
Live departures
Sanford, FL to Florence, SC train times
The table below shows live departures for Sanford, FL to Florence, SC trains for today, Friday, April 10. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
 | 1:35 PM Sanford, FL | 9h47 | 11:22 PM Florence, SC | 1 transfer | |
| 11:15 PM Sanford, FL | 24h07 | 11:22 PM Florence, SC | 1 transfer | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Sanford, FL to Florence, SC by train or bus
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Train from Sanford, FL to Florence, SC
USAUSA
Trains from Sanford, FL to Florence, SC run on average 6 times per day, taking around 12h 39m. Cheap train tickets for this journey start at $161 (€129) but you can travel from only $133 (€107) by bus.
There are 3 trains per day. The earliest train runs at 03:18, the last at 19:49. The fastest train covers the 383 miles (617 km) distance in 9h 47m.
Distance 383 miles (617 km) |
Average train duration 12h 39m |
Cheapest ticket price $161 (€129) |
Trains per day 6 |
Direct trains 3 |
Fastest train 9h 47m |
First train 3:18 AM |
Last train 7:49 PM |
Train companies: SunRail from Sanford, FL to Florence, SC trainsSunRail trains will get you between Sanford, FL and Florence, SC from $133 (€107). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
SunRail
FAQs: Trains from Sanford, FL to Florence, SC
Find answers to the most common questions about traveling from Sanford, FL to Florence, SC by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Florence, SC, this guide helps you travel smarter and with confidence.
popular train stations
Popular train stations from Sanford, FL to Florence, SC
LockersParkingDiningTaxisAccessibilityWCHotelLost and Found OfficeTicket OfficeInformation DeskLuggage Carts
- 6:00 AM - 11:00 PM Monday - Sunday
- Parking is available at the station.
- Outside the main entrance.
- Elevators, ramps.
- Aloft Florence
- Hyatt Place Florence Downtown
- Hotel Florence, Tapestry Collection by Hilton
- Located in the main hall
- Located in the main hall
- Free
- The station has an enclosed waiting area.
- Bus: Greyhound services available nearby
Most popular train connections from Sanford, FL
More options for your journey from Sanford, FL to Florence, SC
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Most popular trains to and from Florence, SC and Sanford, FL
Most popular train connections to Florence, SC
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