The cheapest and fastest trains from Sanford, FL to Florence, SC
Cheapest price
$121
Average price
$121
Fastest journey
8 h 42 m
Average duration
8 h 42 m
Trains per day
1
Distance
617 km
The best way to find a cheap train ticket from Sanford, FL to Florence, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Sanford, FL to Florence, SC will cost around $121 if you buy it on the day, but the cheapest tickets can be found for only $121.
Of the 1 trains that leave Sanford, FL for Florence, SC on Thu, May 28, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, May 28 the direct trains cover the 617 km distance in an average of 8 h 42 m but if you time it right, some trains will get you there in just 8 h 42 m .
On Thu, May 28 the slowest trains will take 8 h 42 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
5:40 PM8h42Sanford, FL2:22 AMFlorence, SC$1211One-way0 transfers
5:40 PM8h42Sanford, FL2:22 AMFlorence, SC$1211One-way0 transfers
Travel Information
Compare train and bus for Sanford, FL to Florence, SC
Omio recommends booking the bus as it is the most popular option from Sanford, FL to Florence, SC among Omio's users. If you are prioritising price take the bus with prices starting from $97. For those with little time consider booking a train which can get you there in 11h 51m. The ticket price range depends on the travel mode: a bus costs an average of $97, and a train costs an average of $121.
Distance: 383 miles (617 km)
Compare train with
| Train | Most popular Bus |
|---|---|
$124 Average price | $97 Average price Cheapest |
12h 21m Average total duration Fastest 11h 51m Onboard + 30m Additional time* | 18h 7m Average total duration 17h 37m Onboard + 30m Additional time* |
Direct Options | Direct Options |
This is compared to other travel options from Sanford, FL to Florence, SC:
A bus is $27 (€22) less than a train for this route with tickets for a train from Sanford, FL to Florence, SC costing on average $124 (€100).
Other travel options to Florence, SC take longer:
Bus takes on average 17h 37m.
Live departures
Sanford, FL to Florence, SC train times
The table below shows live departures for Sanford, FL to Florence, SC trains for today, Wednesday, May 27. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 11:49 PM Sanford, FL | 15h00 | 2:49 PM Florence, SC | 0 transfersDirect | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Sanford, FL to Florence, SC by train or bus
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
May 28
May 29
May 30
May 31
Jun 01
Jun 02
Jun 03
Journey information
Overview: Train from Sanford, FL to Florence, SC
Trains from Sanford, FL to Florence, SC run on average 5 times per day, taking around 11h 51m. Cheap train tickets for this journey start at $121 (€98) but you can travel from only $97 (€78) by bus.
There are 2 trains per day. The earliest train runs at 03:18, the last at 19:49. The fastest train covers the 383 miles (617 km) distance in 8h 42m.
Distance 383 miles (617 km) |
Average train duration 11h 51m |
Cheapest ticket price $121 (€98) |
Trains per day 5 |
Direct trains 2 |
Fastest train 8h 42m |
First train 3:18 AM |
Last train 7:49 PM |
Cheapest Month Aug |
Cheapest Day Tue |
High Season Apr - Jun |
Low Season Jan - Mar |
Train companies: SunRail from Sanford, FL to Florence, SC trainsSunRail trains will get you between Sanford, FL and Florence, SC from $97 (€78). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
SunRail
FAQs: Trains from Sanford, FL to Florence, SC
Find answers to the most common questions about traveling from Sanford, FL to Florence, SC by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Florence, SC, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Sanford, FL to Florence, SC
- 6:00 AM - 11:00 PM Monday - Sunday
- Parking is available at the station.
- Outside the main entrance.
- Elevators, ramps.
- Aloft Florence
- Hyatt Place Florence Downtown
- Hotel Florence, Tapestry Collection by Hilton
- Located in the main hall
- Located in the main hall
- Free
- The station has an enclosed waiting area.
- Bus: Greyhound services available nearby
Most popular train connections from Sanford, FL
More options for your journey from Sanford, FL to Florence, SC
Here are some other resources that might have the information you need
