The cheapest and fastest trains from Sanford, FL to Florence, SC
Cheapest price
$119
Average price
$119
Fastest journey
8 h 42 m
Average duration
8 h 42 m
Trains per day
1
Distance
617 km
The best way to find a cheap train ticket from Sanford, FL to Florence, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Sanford, FL to Florence, SC will cost around $119 if you buy it on the day, but the cheapest tickets can be found for only $119.
Of the 1 trains that leave Sanford, FL for Florence, SC on Tue, Dec 23, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Tue, Dec 23 the direct trains cover the 617 km distance in an average of 8 h 42 m but if you time it right, some trains will get you there in just 8 h 42 m .
On Tue, Dec 23 the slowest trains will take 8 h 42 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Travel Information
Compare train and bus for Sanford, FL to Florence, SC
Omio recommends booking the bus as it is the most popular option from Sanford, FL to Florence, SC among Omio's users. If you are prioritising price take the train with prices starting from €77. For those with little time consider booking a train which can get you there in 9h 58m. The ticket price range depends on the travel mode: a train costs an average of €77, and a bus costs an average of €108.
Distance: 383 miles (617 km)
Compare train with
| Train | Most popular Bus |
|---|---|
€89 Average price Cheapest | €108 Average price |
10h 28m Average total duration Fastest 9h 58m Onboard + 30m Additional time* | 19h 43m Average total duration 19h 13m Onboard + 30m Additional time* |
Direct Options | Direct Options |
Compare prices and tickets Sanford, FL to Florence, SC by train or bus
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Dec 23
Dec 24
Dec 25
Dec 26
Dec 27
Dec 28
Dec 29
Why should you book Sanford to Florence trains with Omio?
SunRail operates all train services from Sanford to Florence. Omio is the only official third party seller for SunRail tickets.
Why book with Omio vs SunRail?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare SunRail with all available travel options, which are train and bus to ensure you get the best deal for traveling from Sanford to Florence.
Why book with Omio over Trainline and Rail Europe?
- Official reseller: SunRail tickets can only be bought on Omio or SunRail's website as Omio is the only official third party seller for SunRail tickets. Trainline, RailEurope, and Rail.Ninja do not sell SunRail tickets as they are not official sellers.
- Multiple modes of transport: Omio allows you to compare travel options including train and bus to find the ideal travel option from Sanford to Florence.
Journey information
Overview: Train from Sanford, FL to Florence, SC
Trains from Sanford, FL to Florence, SC run on average 6 times per day, taking around 9h 58m. Cheap train tickets for this journey start at $97 (€77) if you book in advance.
There are 3 trains per day. The earliest train runs at 03:18, the last at 19:49. The fastest train covers the 383 miles (617 km) distance in 8h 42m.
Distance 383 miles (617 km) |
Average train duration 9h 58m |
Cheapest ticket price $97 (€77) |
Trains per day 6 |
Direct trains 3 |
Fastest train 8h 42m |
First train 03:18 |
Last train 19:49 |
Train companies: SunRail from Sanford, FL to Florence, SC trainsSunRail trains will get you between Sanford, FL and Florence, SC from $97 (€77). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
SunRail
FAQs: Trains from Sanford, FL to Florence, SC
Find answers to the most common questions about traveling from Sanford, FL to Florence, SC by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Florence, SC, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Sanford, FL to Florence, SC
- 6:00 AM - 11:00 PM Monday - Sunday
- Parking is available at the station.
- Outside the main entrance.
- Elevators, ramps.
- Aloft Florence
- Hyatt Place Florence Downtown
- Hotel Florence, Tapestry Collection by Hilton
- Located in the main hall
- Located in the main hall
- Free
- The station has an enclosed waiting area.
- Bus: Greyhound services available nearby
Most popular train connections from Sanford, FL
More options for your journey from Sanford, FL to Florence, SC
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