- Must visit
Uffizi Gallery
Celebrated art museum with Botticelli, Leonardo, and Michelangelo. A cornerstone visit for Renaissance painting and one of Florence’s defining experiences.
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Journey information
Overview: Train from Sanford, FL to Florence, SC
USAUSA
Take a train from Sanford, FL to Florence, SC and enjoy the approximately 383 miles (617 km) long journey. Find schedules and pricing options for a convenient and affordable trip.
The earliest train runs at 03:18, the last at 19:49.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 383 miles (617 km) |
First train 3:18 AM |
Last train 7:49 PM |
Cheapest Month Oct |
Cheapest Day Sat |
High Season Apr - Jun |
Low Season Jan - Mar |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Live departures
Sanford, FL to Florence, SC train times
The table below shows live departures for Sanford, FL to Florence, SC trains for today, Friday, October 9. You can also manually refresh the results below to see updated train journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
 | 1:35 PM Sanford, FL | 9h47 | 11:22 PM Florence, SC | 1 transfer | |
| 11:15 PM Sanford, FL | 24h07 | 11:22 PM Florence, SC | 1 transfer | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Train companies: SunRail from Sanford, FL to Florence, SC trainsSunRail trains will get you between Sanford, FL and Florence, SC. With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
SunRail
Luggage & cancellation policy
Average SunRail Duration
9h 47m
Cheapest SunRail Price
€173
SunRail frequency
1 a day
Complete guide to Florence, SC
Things to do in Florence, SC
Discover the best of Florence, SC — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Florence, SC trip today.
- Must visit
Galleria dell'Accademia
Museum centered on Michelangelo’s David, plus sculptures and paintings. Essential for seeing one of Florence’s most famous masterpieces up close.
- Recommended
Museo dell'Opera del Duomo
Interactive museum inside the cathedral complex exploring Brunelleschi’s dome, tools, and original artworks. Ideal for understanding Florence’s cathedral story.
- Must visit
Piazza della Signoria
Grand civic square framed by Palazzo Vecchio and open-air sculptures. It is one of Florence’s key meeting points and a natural starting place for exploration.
- Must visit
Piazzale Michelangelo
Hilltop terrace with sweeping city views, especially at sunset. A classic Florence panorama and a rewarding walk or short bus ride from the center.
- Recommended
Boboli Gardens
Large formal garden behind Pitti Palace with paths, fountains, and viewpoints. Excellent for a slower visit combining greenery, sculpture, and city vistas.
- Gluten-free
Pee Dee Pulled Pork BBQ
Pulled pork barbecue is a Pee Dee staple, slow-smoked until tender and served with the region's tangy vinegar-pepper sauce.
- Gluten-free
Smoked Pork Ribs
Smoked pork ribs are common at local barbecue joints, seasoned simply and cooked low and slow for deep smoke flavor.
- Gluten-free
Shrimp and Grits
Shrimp and grits is a South Carolina classic: local shrimp over creamy grits, often enriched with bacon, gravy, or butter.
Victors
Upscale downtown restaurant serving refined Southern dishes, steaks, seafood, and cocktails in a polished space.
Wholly Smokin' Downtown
Casual local favorite for Carolina barbecue, ribs, and classic Southern sides in a relaxed family setting.
Holt Bros BBQ
Popular casual spot known for barbecue plates, pulled pork, and generous Southern comfort food portions.
$ US Dollar
Moderate by U.S. small-city standards. Hotels are usually cheaper than major tourist cities, while dining and car-based transport remain fairly typical for the region.
Average meal costs
- Budget
- $8-12 for fast food or casual takeout.
- Mid-range
- $15-25 per person for a casual sit-down meal.
- Fine dining
- $35+ per person for upscale restaurants.
- Coffee
- $3-5 for regular coffee or latte.
Tipping culture
Tip 15-20% at restaurants. Round up or add 10-15% for taxis if service is good. Small change is fine at cafes.
FAQs: Trains from Sanford, FL to Florence, SC
Find answers to the most common questions about traveling from Sanford, FL to Florence, SC by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Florence, SC, this guide helps you travel smarter and with confidence.
The first train from Sanford, FL to Florence, SC leaves at 3:18 AM.
The distance by train from Sanford, FL to Florence, SC is 383 miles (617 km).
The last train from Sanford, FL to Florence, SC leaves at 7:49 PM.
There is no high speed train available from Sanford, FL to Florence, SC.
There is no direct train service currently available from Sanford, FL to Florence, SC.
Unfortunately, there is no night train available from Sanford, FL to Florence, SC.
The train journey from Sanford, FL to Florence, SC offers a mix of scenic views, primarily showcasing the lush landscapes of the Southeastern United States, including stretches of green forests, charming small towns, and glimpses of the region's rivers and lakes.
Yes, you can take the train from Sanford, FL to Florence, SC.
Popular day trips by train from Florence, SC include Charleston, SC, Kingstree, SC.
Items not allowed on trains typically include hazardous materials such as explosives, flammable liquids, corrosive substances, and illegal drugs. Additionally, large or bulky items that may obstruct aisles or emergency exits, as well as pets without proper carriers, may be restricted. Specific prohibited items can vary by train operator and region, so please check the rules for your particular journey.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Florence, SC, travelers should be cautious of petty crimes like pickpocketing and vehicle break-ins, especially in less crowded areas. It's advisable to stay in well-lit, populated places and avoid displaying valuables openly. Common scams include overcharging by taxi drivers and unofficial ticket sellers; always use licensed transportation and purchase tickets from authorized vendors. Staying aware of surroundings and securing personal belongings helps ensure a safe visit.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular train stations
Popular train stations from Sanford, FL to Florence, SC
Most Sanford, FL to Florence, SC trains use the DeLand Station to Florence Station station pair. Use this guide to compare Sanford, FL and Florence, SC train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Departure train stations in Sanford
Arrival train stations in Florence
Which Florence, SC station do trains from Sanford, FL arrive at?
Trains from Sanford, FL to Florence, SC arrive at Florence Station. Florence Station is 0 miles (1 km) from Florence, SC city centre.
Florence Station805 East Day Street, Florence, SC 29506, USA+1 800-872-7245
City-centre transport
Getting to Florence Station from Florence city centre
BusGreyhound services available nearby
Florence Station train station facilities and services
Florence Station has practical services for this route, including Lockers, Parking, Dining, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Information Desk, and Luggage Carts.
Food and drink
Food and drink options are available at Florence Station.
Tickets and information
Ticket office support is available at Florence Station. Information desks are located in the main hall.
Luggage and lost property
Luggage storage is available at Florence Station. Lost and found is available at the station.
Parking, taxis and toilets
Available at Florence Station: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Florence Station: Elevators, ramps.
Shops, hotels and contact
Nearby hotels include Aloft Florence, Hyatt Place Florence Downtown, Hotel Florence, Tapestry Collection by Hilton.
Most popular train connections from Sanford, FL
More options for your journey from Sanford, FL to Florence, SC
Here are some other resources that might have the information you need
Most popular trains to and from Florence, SC and Sanford, FL
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