- Must visit
Alabama Museum of Natural History
Main university museum featuring natural history, archaeology, and regional exhibits, with broad appeal for first-time visitors.
Omio recommends booking the train as it is the most popular option from Greenville, SC to Tuscaloosa, AL among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $80 For those with little time, consider booking a flight, which has an average total journey time of 5h 26m. Average ticket prices depend on the travel mode: a bus costs an average of $80, while a flight costs an average of $716.
Distance: 317 miles (511 km)
Most popular Train | Bus | Flight | Driving |
|---|---|---|---|
$107 Average price | $80 Average price Cheapest | $716 Average price | $71 Average price (fuel + tolls) |
9h 57m Average total duration 9h 27m Onboard + 30m Additional time* | 9h 1m Average total duration 8h 31m Onboard + 30m Additional time* | 5h 26m Average total duration Fastest 3h 26m Onboard + 2h 0m Additional time* | 5h 15m Average total duration (door-to-door) |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Greenville, SC to Tuscaloosa, AL:
A bus is $26 less than a train for this route with tickets for a train from Greenville, SC to Tuscaloosa, AL costing on average $107.
A bus is $635 less than a flight for this route with tickets for a flight from Greenville, SC to Tuscaloosa, AL costing on average $716.
Other travel options to Tuscaloosa, AL take longer:
Bus takes on average 8h 31m.
Train takes on average 9h 27m.
Tickets start at around $107 compared to roughly $71 in fuel and tolls — a saving of about $-36.09. The journey takes 9h 27m versus 5h 15m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Trains from Greenville, SC to Tuscaloosa, AL run on average 1 times per day, taking around 9h 27m. Cheap train tickets for this journey start at $106 but you can travel from only $51 by bus.
There are 1 trains per day. The earliest train runs at 05:31, the last at 15:14. The fastest train covers the 317 miles (511 km) distance in 9h 27m.
Distance 317 miles (511 km) |
Average train duration 9h 27m |
Cheapest ticket price $106 |
Trains per day 1 |
Direct trains 1 |
Fastest train 9h 27m |
First train 5:31 AM |
Last train 3:14 PM |
Cheapest Month Oct |
Cheapest Day Fri |
High Season Jul - Sep |
Low Season Jan - Mar |
Discover the best of Tuscaloosa, AL — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Tuscaloosa, AL trip today.
Main university museum featuring natural history, archaeology, and regional exhibits, with broad appeal for first-time visitors.
Contemporary gallery on campus presenting rotating exhibitions by regional and national artists in a compact modern space.
Student-centered art museum with rotating exhibitions and programs that highlight contemporary practice and campus creativity.
Riverfront park with trails, green space, and event areas, ideal for relaxed walks and views near downtown.
Popular downtown district with shops, nightlife, public art, and frequent events, making it a practical base for exploring on foot.
Large campus green framed by historic university buildings, suited to walking, photos, and a sense of campus traditions.
Find answers to the most common questions about traveling from Greenville, SC to Tuscaloosa, AL by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Tuscaloosa, AL, this guide helps you travel smarter and with confidence.

Most Greenville, SC to Tuscaloosa, AL trains use the Greenville Station to Tuscaloosa Station station pair. Use this guide to compare Greenville, SC and Tuscaloosa, AL train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Greenville Station is 1 km from Greenville city centre. Public transport options include:
Greenville Station has practical services for this route, including Wifi, Lockers, Parking, Dining, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Information Desk, and Luggage Carts.
Food options include: Soby's, Larkin's on the River
Free.
Ticket office support is available at Greenville Station. Information desks are located in the main hall.
Luggage storage is available at Greenville Station. Lost and found is available at the station.
Available at Greenville Station: Parking, Taxis, WC.
Available at Greenville Station: Bike Parking, Bike Rental.
Accessibility facilities are available at Greenville Station: Ramps, assistance.
Nearby hotels include The Westin Poinsett, Greenville, Courtyard Greenville Downtown, Hyatt Regency Greenville.
Tuscaloosa Station is 2 km from Tuscaloosa city centre. Check local transport options before travel.
Tuscaloosa Station has practical services for this route, including Accessibility.
Accessibility facilities are available at Tuscaloosa Station.
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