Travel Information
Compare bus, train, and flight for Durham, NC to Jacksonville, FL
Omio recommends booking the train as it is the most popular option from Durham, NC to Jacksonville, FL among Omio's users. If you are prioritising price take the train with prices starting from $130. For those with little time consider booking a flight which can get you there in 3h 44m. The ticket price range depends on the travel mode: a train costs an average of $130, and a flight costs an average of $201.
Distance: 422 miles (680 km)
Compare train with
Most popular Train | Bus | Flight | Driving |
|---|---|---|---|
$164 Average price Cheapest | $186 Average price | $319 Average price | $94 Average price (fuel + tolls) |
10h 52m Average total duration 10h 22m Onboard + 30m Additional time* | 14h 14m Average total duration 13h 44m Onboard + 30m Additional time* | 6h 44m Average total duration Fastest 3h 44m Onboard + 3h 0m Additional time* | 6h 50m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Durham, NC to Jacksonville, FL:
A train is $22 (€17) less than a bus for this route with tickets for a bus from Durham, NC to Jacksonville, FL costing on average $186 (€150).
A train is $154 (€125) less than a flight for this route with tickets for a flight from Durham, NC to Jacksonville, FL costing on average $319 (€257).
Other travel options to Jacksonville, FL take longer:
Train takes on average 10h 22m.
Bus takes on average 13h 44m.
Tickets start at around $164 (€133) compared to roughly $94 (€76) in fuel and tolls — a saving of about $-70.04 (€-56.56). The journey takes 10h 22m versus 6h 50m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
Compare prices and tickets Durham, NC to Jacksonville, FL by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Train from Durham, NC to Jacksonville, FL
Trains from Durham, NC to Jacksonville, FL run on average 3 times per day, taking around 10h 22m. Cheap train tickets for this journey start at $130 (€105) if you book in advance.
The earliest train runs at 17:01, the last at 22:33. The fastest train covers the 422 miles (680 km) distance in 13h 31m.
Distance 422 miles (680 km) |
Average train duration 10h 22m |
Cheapest ticket price $130 (€105) |
Trains per day 3 |
Fastest train 13h 31m |
First train 5:01 PM |
Last train 10:33 PM |
Cheapest Month Jul |
Cheapest Day Wed |
High Season Jan - Mar |
Low Season Jul - Sep |
Busiest Day Mon |
Least Busy Day Mon |
Train companies: Amtrak from Durham, NC to Jacksonville, FL trainsAmtrak trains will get you between Durham, NC and Jacksonville, FL from $130 (€105). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Amtrak
FAQs: Trains from Durham, NC to Jacksonville, FL
Find answers to the most common questions about traveling from Durham, NC to Jacksonville, FL by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Jacksonville, FL, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Durham, NC to Jacksonville, FL
- 6:30 AM - 9:00 PM Monday - Sunday
- Free
- Parking is available nearby, with several public parking options in the vicinity.
- Parker and Otis
- Dame's Chicken & Waffles
- Outside the main entrance.
- Ramps.
- Free of charge
- Durham Marriott City Center
- 21c Museum Hotel Durham
- Aloft Durham Downtown
- Located in the main hall
- Located in the main hall
- Free
- Hall 1: main entrance, ticketing, and waiting area
- Hall 2: platform access
- Bus: GoDurham buses available
- Amtrak Thruway buses
- 6:00 AM - 11:00 PM Monday - Sunday
- Parking is available at the station.
- Outside the main entrance.
- Ramps, restrooms.
- Located in the main hall
- Free
- The station has an enclosed waiting area.
- Bus: Several lines available
More options for your journey from Durham, NC to Jacksonville, FL
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