The cheapest and fastest trains from Durham, NC to Jacksonville, FL
Cheapest price
$232
Average price
$234
Fastest journey
13 h 31 m
Average duration
13 h 31 m
Trains per day
2
Distance
680 km
The best way to find a cheap train ticket from Durham, NC to Jacksonville, FL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Durham, NC to Jacksonville, FL will cost around $234 if you buy it on the day, but the cheapest tickets can be found for only $232.
It's difficult to get from Durham, NC to Jacksonville, FL without transferring at least once.
74 Piedmont · 41 Floridian5:01 PM13h31Durham Station, Durham, NC6:32 AMJacksonville station, Jacksonville, FL$2321One-way1 transfer
74 Piedmont · 41 Floridian5:01 PM13h31Durham Station, Durham, NC6:32 AMJacksonville station, Jacksonville, FL$2351One-way1 transfer
74 Piedmont · 41 Floridian5:01 PM13h31Durham Station, Durham, NC6:32 AMJacksonville station, Jacksonville, FL$2321One-way1 transfer
74 Piedmont · 41 Floridian5:01 PM13h31Durham Station, Durham, NC6:32 AMJacksonville station, Jacksonville, FL$2351One-way1 transfer
Travel Information
Compare bus, train, and flight for Durham, NC to Jacksonville, FL
Omio recommends booking the train as it is the most popular option from Durham, NC to Jacksonville, FL among Omio's users. If you are prioritising price take the train with prices starting from $106. For those with little time consider booking a flight which can get you there in 4h 47m. The ticket price range depends on the travel mode: a train costs an average of $106, and a flight costs an average of $374.
Distance: 422 miles (680 km)
Compare train with
Most popular Train | Bus | Flight |
|---|---|---|
$122 Average price Cheapest | $166 Average price | $391 Average price |
10h 56m Average total duration 10h 26m Onboard + 30m Additional time* | 17h 1m Average total duration 16h 31m Onboard + 30m Additional time* | 7h 47m Average total duration Fastest 4h 47m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
Live departures
Durham, NC to Jacksonville, FL train times
The table below shows live departures for Durham, NC to Jacksonville, FL trains for today, Wednesday, April 1. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 10:01 PM Durham, NC | 13h31 | 11:32 AM Jacksonville, FL | 0 transfersDirect | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Durham, NC to Jacksonville, FL by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Train from Durham, NC to Jacksonville, FL
Trains from Durham, NC to Jacksonville, FL run on average 3 times per day, taking around 10h 26m. Cheap train tickets for this journey start at $106 (€85) if you book in advance.
The earliest train runs at 17:01, the last at 22:33. The fastest train covers the 422 miles (680 km) distance in 13h 31m.
Distance 422 miles (680 km) |
Average train duration 10h 26m |
Cheapest ticket price $106 (€85) |
Trains per day 3 |
Fastest train 13h 31m |
First train 5:01 PM |
Last train 10:33 PM |
Train companies: Amtrak from Durham, NC to Jacksonville, FL trainsAmtrak trains will get you between Durham, NC and Jacksonville, FL from $106 (€85). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Amtrak
FAQs: Trains from Durham, NC to Jacksonville, FL
Find answers to the most common questions about traveling from Durham, NC to Jacksonville, FL by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Jacksonville, FL, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Durham, NC to Jacksonville, FL
- 6:30 AM - 9:00 PM Monday - Sunday
- Free
- Parking is available nearby, with several public parking options in the vicinity.
- Parker and Otis
- Dame's Chicken & Waffles
- Outside the main entrance.
- Ramps.
- Free of charge
- Durham Marriott City Center
- 21c Museum Hotel Durham
- Aloft Durham Downtown
- Located in the main hall
- Located in the main hall
- Free
- Hall 1: main entrance, ticketing, and waiting area
- Hall 2: platform access
- Bus: GoDurham buses available
- Amtrak Thruway buses
- 6:00 AM - 11:00 PM Monday - Sunday
- Parking is available at the station.
- Outside the main entrance.
- Ramps, restrooms.
- Located in the main hall
- Free
- The station has an enclosed waiting area.
- Bus: Several lines available
More options for your journey from Durham, NC to Jacksonville, FL
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