Jacksonville, FL to Greenville, SC train with Amtrak

Fri, Nov 28
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Amtrak
Regionale
Deutsche Bahn
Italo
iryo
1,000+ travel companies
Amtrak
Regionale
Deutsche Bahn
Italo
iryo
1,000+ travel companies
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Travel Information

Compare bus and flight for Jacksonville, FL to Greenville, SC

Omio recommends booking the bus as it is the most popular option from Jacksonville, FL to Greenville, SC among Omio's users. If you are prioritising price take the bus with prices starting from €91. For those with little time consider booking a flight which can get you there in 9h 22m. The ticket price range depends on the travel mode: a bus costs an average of €91, and a flight costs an average of €732.

Distance: 315 miles (507 km)

Compare bus with

Most popular
Bus
Flight

€91

Average price

Cheapest

€732

Average price

10h 30m

Average total duration

10h 0m

Onboard

+

30m

Additional time*

12h 22m

Average total duration

Fastest

9h 22m

Onboard

+

3h 0m

Additional time*

Direct Options

Direct Options

Compare prices and tickets Jacksonville, FL to Greenville, SC by bus or flight

Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Fri
Nov 28
Sat
Nov 29
Sun
Nov 30
Mon
Dec 01
Tue
Dec 02
Wed
Dec 03
Thu
Dec 04

Why should you book Jacksonville to Greenville trains with Omio?

Amtrak operates all train services from Jacksonville to Greenville. Omio is the only official third party seller for Amtrak tickets.

Why book with Omio vs Amtrak?

  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare Amtrak with all available travel options, which are bus and flight to ensure you get the best deal for traveling from Jacksonville to Greenville.

Why book with Omio over Trainline and Rail Europe?

Multiple modes of transport
  • Official reseller: Amtrak tickets can only be bought on Omio or Amtrak's website as Omio is the only official third party seller for Amtrak tickets. Trainline, RailEurope, and Rail.Ninja do not sell Amtrak tickets as they are not official sellers.
  • Multiple modes of transport: Omio allows you to compare travel options including bus and flight to find the ideal travel option from Jacksonville to Greenville.

Journey information

Overview: Train from Jacksonville, FL to Greenville, SC

USAUSA
USAUSA
Icon of train

Take a train from Jacksonville, FL to Greenville, SC and enjoy the approximately 315 miles (507 km) long journey. Find schedules and pricing options for a convenient and affordable trip.

The earliest train runs at 02:23, the last at 22:33.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $112 (€91)
Distance
315 miles (507 km)
Average train duration
25h 8m
Trains per day
2
First train
02:23
Last train
22:33
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $112 (€91)

Train companies: Amtrak from Jacksonville, FL to Greenville, SC trainsAmtrak trains will get you between Jacksonville, FL and Greenville, SC from $112 (€91). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.

Amtrak

About
Amtrak is the main passenger train operator in the United States, providing medium- and long-distance intercity services across 46 states and three Canadian provinces. Operating over 300 trains daily and serving more than 500 destinations, Amtrak connects cities and regions nationwide through routes such as the high-speed Acela in the Northeast Corridor, the scenic Coast Starlight along the West Coast, and the Empire Builder linking Chicago to the Midwest and the Pacific Northwest. Other notable services include the Northeast Regional, Keystone Service, and the unique Auto Train, which allows passengers to bring their cars onboard. Amtrak offers a variety of classes to suit different budgets and travel needs, including Coach, Business, First Class, and Sleeper Class with options like Roomettes, Bedrooms, and Bedroom Suites for overnight journeys. Ticket types include Saver, Value, Flexible, Business, and Premium. Onboard amenities vary by service but may include comfortable seating, Wi-Fi, power outlets, dining options, and lounge access on select trains. Popular routes include Washington, D.C.–Boston, San Diego–San Luis Obispo, San Jose–Sacramento, and Chicago–Seattle.
Luggage & cancellation policy
Average Duration
36h 13m
Cheapest Price
$1314 (€1063)
Amtrak frequency
2 a day
Luggage included
2 personal items and 2 carry-on bags included free
Luggage storage
Overhead racks, under seats, and designated luggage areas at end of cars
Cancellation Policy
Cancellation policies depend on ticket type and timing
Refund
Full refund if train is canceled by Amtrak
Amenities on board the train
Wifi
Food sold onboard
Café car with snacks, beverages, and light meals. Long-distance trains have full-service dining cars
Seat reservation
Included in ticket price for Business and First Class. Optional fee for Coach Class
Toilets
USB plugs
Accessibility
Wheelchair spaces, accessible restrooms, Red Cap assistance service, accessible platforms and stations
Pets
Small pets under 20 pounds allowed for $26 fee. Must be in carrier. Service animals travel free
Quiet zone

FAQs: Trains from Jacksonville, FL to Greenville, SC

Find answers to the most common questions about traveling from Jacksonville, FL to Greenville, SC by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Greenville, SC, this guide helps you travel smarter and with confidence.

FAQs
A 2-3 day trip is ideal for exploring Greenville, SC, allowing time to enjoy its downtown area, Falls Park on the Reedy, and the local culinary scene.
The cheapest way to get from Jacksonville, FL to Greenville, SC is by bus, with a cost of around $112 (€91).
There is no high speed train available from Jacksonville, FL to Greenville, SC.
Yes, you can take the train from Jacksonville, FL to Greenville, SC.
The train station in Jacksonville, FL that goes to Greenville, SC is Jacksonville station, Jacksonville, FL, which connects to Greenville Station, Greenville, SC.
Unfortunately, there is no night train available from Jacksonville, FL to Greenville, SC.
The distance by train from Jacksonville, FL to Greenville, SC is 315 miles (507 km).
The first train from Jacksonville, FL to Greenville, SC leaves at 2:23 AM.
The last train from Jacksonville, FL to Greenville, SC leaves at 10:33 PM.
There is no direct train service currently available from Jacksonville, FL to Greenville, SC.
The train journey from Jacksonville, FL to Greenville, SC offers a mix of urban and natural scenery, with views of lush Southern landscapes, small towns, and stretches of forests, providing a pleasant and occasionally scenic experience.

popular train stations

Popular train stations from Jacksonville, FL to Greenville, SC

Jacksonville
Greenville
The major train station for departures in Jacksonville is Jacksonville Station. Find all the information you need to know about services, amenities and connections at Jacksonville Station for your trip from Jacksonville to Greenville.
Jacksonville StationParkingTaxisAccessibilityWCTicket OfficeInformation DeskLuggage Carts
Amenities at train station
ParkingParking
TaxisTaxis
AccessibilityAccessibility
WCWC
Ticket OfficeTicket Office
Information DeskInformation Desk
Luggage CartsLuggage Carts
information
phone
Phone Number
ticketOfficeHours
Ticket Office Hours
  • 6:00 AM - 11:00 PM Monday - Sunday
ticketOfficeHours
Distance to city center
7 km
platformCount
Number of platforms
1
Parking
Parking
  • Parking is available at the station.
Taxis
Taxis
  • Outside the main entrance.
Accessibility
Accessibility
  • Ramps, restrooms.
Information Desk
Information Desk
  • Located in the main hall
Luggage Carts
Luggage Carts
  • Free
Station Plan
  • The station has an enclosed waiting area.
Public transit options for Jacksonville Station
  • Bus: Several lines available

Most popular train connections to Greenville, SC

HomeTrainsTrains in USATrain Times to Greenville, SCJacksonville, FL to Greenville, SC train

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