- Must visit
San Francisco Museum of Modern Art
Major contemporary art museum with an outstanding modern and contemporary collection, large-scale installations, and strong photography holdings.
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The cheapest and fastest trains from Greenville, SC to San Francisco, CA
Showing times and prices for Jun 21
Cheapest price
$369
Average price
$422
Fastest journey
3 d 17 h 34 m
Average duration
3 d 17 h 58 m
Trains per day
2
Distance
3574 km
Cheap tickets
The best way to find a cheap train ticket from Greenville, SC to San Francisco, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Greenville, SC to San Francisco, CA will cost around $422 if you buy it on the day, but the cheapest tickets can be found for only $369.
Fast trains
Of the 2 trains that leave Greenville, SC for San Francisco, CA on Sun, Jun 21, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sun, Jun 21 the direct trains cover the 3574 km distance in an average of 3 d 17 h 58 m but if you time it right, some trains will get you there in just 3 d 17 h 34 m .
On Sun, Jun 21 the slowest trains will take 3 d 18 h 22 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
7:23 AM89h34Greenville, SC12:57 AMSan Francisco, CA$3691One-way0 transfers- 6:23 AM90h22Greenville, SC12:45 AMSan Francisco, CA$4751One-way0 transfers
- 7:23 AM89h34Greenville, SC12:57 AMSan Francisco, CA$3691One-way0 transfers
- 6:23 AM90h22Greenville, SC12:45 AMSan Francisco, CA$4751One-way0 transfers
Travel Information
Compare bus, train, and flight for Greenville, SC to San Francisco, CA
Omio recommends booking the flight as it is the most popular option from Greenville, SC to San Francisco, CA among Omio's users. If you are prioritising price take the bus with prices starting from $147. For those with little time consider booking a flight which can get you there in 7h 54m. The ticket price range depends on the travel mode: a bus costs an average of $147, and a train costs an average of $369.
Distance: 2220 miles (3574 km)
Compare train with
| Train | Most popular Flight | Bus | Driving |
|---|---|---|---|
$1266 Average price | $488 Average price | $414 Average price Cheapest | $534 Average price (fuel + tolls) |
80h 30m Average total duration 80h 0m Onboard + 30m Additional time* | 10h 54m Average total duration Fastest 7h 54m Onboard + 3h 0m Additional time* | 58h 23m Average total duration 57h 53m Onboard + 30m Additional time* | 38h 20m Average total duration (door-to-door) |
Most popular train company |  Most popular airline |  Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
The cheapest way to travel from Greenville, SC to San Francisco, CA is a bus with an average price of $414 (€339).
This is compared to other travel options from Greenville, SC to San Francisco, CA:
A bus is $74 (€60) less than a flight for this route with tickets for a flight from Greenville, SC to San Francisco, CA costing on average $488 (€399).
A bus is $852 (€697) less than a train for this route with tickets for a train from Greenville, SC to San Francisco, CA costing on average $1266 (€1036).
The fastest way to travel from Greenville, SC to San Francisco, CA is by flight with an average journey time of 7h 54m.
Other travel options to San Francisco, CA take longer:
Bus takes on average 57h 53m.
Train takes on average 80h 0m.
It's helpful to compare your options as there are 3 ways to travel between Greenville, SC and San Francisco, CA including taking a bus, train, and flight.
We recommend using the flight as it is the most popular way to get from Greenville, SC to San Francisco, CA among Omio's users.
Take the train. It's the cheaper option, and the extra time on board is usually more relaxing than driving it.
Tickets start at around $1266 (€1036) compared to roughly $534 (€437) in fuel and tolls — a saving of about $-732.44 (€-599.47). The journey takes 80h 0m versus 38h 20m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
Live departures
Greenville, SC to San Francisco, CA train times
The table below shows live departures for Greenville, SC to San Francisco, CA trains for tomorrow, Sunday, June 21. You can also manually refresh the results below to see updated train journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| 6:23 AM Greenville, SC | 90h22 | 12:45 AM San Francisco, CA | 0 transfersDirect | |
| 7:23 AM Greenville, SC | 89h34 | 12:57 AM San Francisco, CA | 0 transfersDirect | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Greenville, SC to San Francisco, CA by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Train from Greenville, SC to San Francisco, CA
USAUSA
Trains from Greenville, SC to San Francisco, CA run on average 1 times per day, taking around 80h 0m. Cheap train tickets for this journey start at $369 (€302) but you can travel from only $147 (€120) by bus.
The earliest train runs at 07:00, the last at 08:25. The fastest train covers the 2220 miles (3574 km) distance in 89h 22m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $147 (€120)
Distance 2220 miles (3574 km) |
Average train duration 80h 0m |
Cheapest ticket price $369 (€302) |
Trains per day 1 |
Fastest train 89h 22m |
First train 7:00 AM |
Last train 8:25 AM |
Cheapest Month Oct |
Cheapest Day Mon |
High Season Jan - Mar |
Low Season Apr - Jun |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $147 (€120)
Train companies: Amtrak from Greenville, SC to San Francisco, CA trainsAmtrak trains will get you between Greenville, SC and San Francisco, CA from $147 (€120). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Amtrak
About
Amtrak is the main passenger train operator in the United States, providing medium- and long-distance intercity services across 46 states and three Canadian provinces. Operating over 300 trains daily and serving more than 500 destinations, Amtrak connects cities and regions nationwide through routes such as the high-speed Acela in the Northeast Corridor, the scenic Coast Starlight along the West Coast, and the Empire Builder linking Chicago to the Midwest and the Pacific Northwest. Other notable services include the Northeast Regional, Keystone Service, and the unique Auto Train, which allows passengers to bring their cars onboard. Amtrak offers a variety of classes to suit different budgets and travel needs, including Coach, Business, First Class, and Sleeper Class with options like Roomettes, Bedrooms, and Bedroom Suites for overnight journeys. Ticket types include Saver, Value, Flexible, Business, and Premium. Onboard amenities vary by service but may include comfortable seating, Wi-Fi, power outlets, dining options, and lounge access on select trains. Popular routes include Washington, D.C.–Boston, San Diego–San Luis Obispo, San Jose–Sacramento, and Chicago–Seattle.
Luggage & cancellation policy
Average Duration
89h 22m
Cheapest Price
$369 (€302)
Luggage included
2 personal items and 2 carry-on bags included free
Luggage storage
Overhead racks, under seats, and designated luggage areas at end of cars
Cancellation Policy
Cancellation policies depend on ticket type and timing
Refund
Full refund if train is canceled by Amtrak
Amenities on board the train
Wifi
Food sold onboard
Café car with snacks, beverages, and light meals. Long-distance trains have full-service dining cars
Seat reservation
Included in ticket price for Business and First Class. Optional fee for Coach Class
Toilets
USB plugs
Accessibility
Wheelchair spaces, accessible restrooms, Red Cap assistance service, accessible platforms and stations
Pets
Small pets under 20 pounds allowed for $26 fee. Must be in carrier. Service animals travel free
Quiet zone
Complete guide to San Francisco
Things to do in San Francisco
Discover the best of San Francisco — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect San Francisco trip today.
- Must visit
Exploratorium
Interactive science and art museum on the Embarcadero, especially popular for hands-on exhibits and bayfront setting.
- Recommended
de Young Museum
Fine arts museum in Golden Gate Park known for American art, textiles, rotating exhibitions, and its panoramic observation tower.
- Must visit
Lombard Street
The famously crooked block lined with flowers and city views, one of San Francisco's most photographed streets.
- Must visit
Golden Gate Park
Massive urban park with gardens, lakes, museums, and broad walking space that rewards both short visits and full-day exploration.
- Must visit
Twin Peaks
High viewpoint with sweeping panoramic views over the city and bay, especially popular at sunset and on clear mornings.
- Gluten-free
Cioppino
A tomato-based seafood stew created by Italian fishermen in San Francisco, usually filled with crab, clams, mussels, shrimp, and fish. It is one of the city’s signature dishes.
- Vegetarian
- Vegan
Sourdough Bread
San Francisco sourdough is famous for its tangy flavor and chewy crust, shaped by the city’s historic baking culture and local wild yeast tradition.
Mission-Style Burrito
A large burrito associated with the Mission District, typically packed with rice, beans, meat, salsa, and extras. It is a defining San Francisco street food.
Sotto Mare
North Beach favorite specializing in cioppino and classic seafood in a lively, casual setting.
La Taqueria
Iconic Mission District taqueria celebrated for Mission-style burritos and tacos with a no-frills local vibe.
The Buena Vista
Classic waterfront cafe famous for Irish Coffee, hearty breakfasts, and historic cable-car-adjacent charm.
United States Dollar
One of the priciest U.S. cities. Hotels, dining, parking, and taxes add up quickly, though transit and casual food can help control costs.
Average meal costs
- Budget
- USD 12-20 for fast casual or food trucks.
- Mid-range
- USD 25-45 per person at a standard restaurant.
- Fine dining
- USD 90+ per person before drinks and tax.
- Coffee
- USD 4-7 for drip coffee or a latte.
Tipping culture
Restaurants: 18-22% is standard before or after tax depending on the screen shown. Bars: USD 1-2 per drink. Taxis/rideshare: 10-15% or round up. Hotel staff: USD 2-5 for porters, a few USD nightly for housekeeping.
FAQs: Trains from Greenville, SC to San Francisco, CA
Find answers to the most common questions about traveling from Greenville, SC to San Francisco, CA by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at San Francisco, CA, this guide helps you travel smarter and with confidence.
Train ticket prices from Greenville, SC to San Francisco, CA can vary. The cheapest ticket starts at $369 (€302), while the average price is around $1266 (€1036).
The train from Greenville, SC to San Francisco, CA runs once a day and takes approximately 89h 22m.
The first train from Greenville, SC to San Francisco, CA leaves at 7:00 AM.
The distance by train from Greenville, SC to San Francisco, CA is 2220 miles (3574 km).
The last train from Greenville, SC to San Francisco, CA leaves at 8:25 AM.
There is no high speed train available from Greenville, SC to San Francisco, CA.
There is no direct train service currently available from Greenville, SC to San Francisco, CA.
Unfortunately, there is no night train available from Greenville, SC to San Francisco, CA.
The train station in Greenville, SC that goes to San Francisco, CA is Greenville Station, Greenville, SC, which connects to Emeryville station, Emeryville, CA.
The cheapest way to get from Greenville, SC to San Francisco, CA is by bus, with a cost of around $147 (€120).
The train journey from Greenville, SC to San Francisco, CA offers scenic views, especially as it passes through diverse landscapes including the rolling hills of the Appalachians, expansive plains, and the dramatic Sierra Nevada mountains before reaching the California coastline.
A day trip from Greenville, SC to San Francisco, CA is not feasible, as the travel duration is 89h 22m with a distance of 2220 miles (3574 km). Moreover, the journey frequency is 2 per day for trains.
In San Francisco, CA, you can ride a cable car through steep streets, explore vibrant murals in the Mission District, and visit the Exploratorium, an interactive science museum. Take a scenic walk along the Embarcadero for views of the Bay Bridge and access to the Ferry Building Marketplace. Enjoy a wine tasting tour in nearby Napa Valley. Key sights include the Golden Gate Bridge, Alcatraz Island, Fisherman's Wharf, Golden Gate Park, and Chinatown, each offering unique experiences from panoramic views to vibrant culture and cuisine.
Three to four days in San Francisco, CA, allows you to explore major attractions like the Golden Gate Bridge, Alcatraz Island, Fisherman's Wharf, and neighborhoods like Chinatown and Haight-Ashbury, while also enjoying some of the city's renowned dining and cultural experiences.
Yes, you can take the train from Greenville, SC to San Francisco, CA.
Since neither Greenville, SC nor San Francisco, CA are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
Popular day trips by train from San Francisco, CA include Davis, CA, San Jose, CA, Stockton, CA, Santa Clara, CA, West Sacramento, CA.
We recommend using the flight as it is the most popular way to get from Greenville, SC to San Francisco, CA among Omio's users.
Items not allowed on trains typically include hazardous materials such as explosives, flammable liquids, corrosive substances, and illegal drugs. Additionally, large or bulky items that may obstruct aisles or emergency exits, as well as pets without proper carriers, may be restricted. Specific prohibited items can vary by train operator and region, so please check the rules for your particular journey.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In San Francisco, travelers should be cautious of pickpocketing and petty theft, especially in crowded areas like Fisherman's Wharf and Union Square. Common scams include distraction techniques used by groups to steal wallets and fake charity solicitations. It's advisable to avoid poorly lit or isolated areas at night and be wary of unofficial taxi services to ensure safety.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular train stations
Popular train stations from Greenville, SC to San Francisco, CA
Greenville
San Francisco
The major train station for departures in Greenville is Greenville Station. Find all the information you need to know about services, amenities and connections at Greenville Station for your trip from Greenville to San Francisco.
Greenville Station
Amenities at train station
WifiLockersParkingDiningTaxisAccessibilityWCHotelLost and Found OfficeTicket OfficeBike ParkingBike RentalInformation DeskLuggage Cartsinformation
Ticket Office Hours
- 6:00 AM - 11:00 PM Monday - Sunday
Distance to city center
1 km
Number of platforms
1Wifi
- Free
Parking
- Parking is available adjacent to the station, open 24/7
Dining
- Soby's
- Larkin's on the River
Taxis
- Outside the main entrance
Accessibility
- Ramps, assistance
WC
- $1.00
Hotel
- The Westin Poinsett, Greenville
- Courtyard Greenville Downtown
- Hyatt Regency Greenville
Lost and Found Office
- Located in the main hall
Information Desk
- Located in the main hall
Luggage Carts
- Free
Station Plan
- The station has a single platform for Amtrak services and a waiting area.
Public transit options for Greenville Station
- Bus: Greenlink Transit Route 3
- Taxi services available
The major train station for arrivals in San Francisco is San Francisco, Mission Street (Chase Bank). Find all the information you need to know about services, amenities and connections at San Francisco, Mission Street (Chase Bank) for your journey to San Francisco from Greenville.
San Francisco, Mission Street (Chase Bank)
information
Most popular train connections from Greenville, SC
More options for your journey from Greenville, SC to San Francisco, CA
Here are some other resources that might have the information you need
Most popular trains to and from San Francisco, CA and Greenville, SC
Most popular train connections to San Francisco, CA
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