- Must visit
California Academy of Sciences
Renowned science museum with rainforest dome, aquarium, and planetarium. Interactive exhibits make it a standout for all ages.
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The cheapest and fastest trains from Greenville, SC to San Francisco, CA
Showing times, prices and bookable tickets for Sep 19
Cheapest price on Sep 19
€749
Average ticket price on Sep 19
€1319
Fastest journey on Sep 19
3 d 17 h 22 m
Average journey duration on Sep 19
3 d 17 h 52 m
Trains on Sep 19
2
Distance
3574 km
Cheap tickets
The best way to find a cheap train ticket from Greenville, SC to San Francisco, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Greenville, SC to San Francisco, CA will cost around €1319 if you buy it on the day, but the cheapest tickets can be found for only €749.
Fast trains
On Sat, Sep 19, we found 2 trains from Greenville, SC to San Francisco, CA, including 2 direct services.
On Sat, Sep 19 the direct trains cover the 3574 km distance in an average of 3 d 17 h 52 m but if you time it right, some trains will get you there in just 3 d 17 h 22 m .
On Sat, Sep 19 the slowest trains will take 3 d 18 h 22 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
7:23 AM89h22Greenville, SC12:45 AMSan Francisco, CA€7491One-way0 transfers- 6:23 AM90h22Greenville, SC12:45 AMSan Francisco, CA€18891One-way0 transfers
- 7:23 AM89h22Greenville, SC12:45 AMSan Francisco, CA€7491One-way0 transfers
- 6:23 AM90h22Greenville, SC12:45 AMSan Francisco, CA€18891One-way0 transfers
Travel Information
Compare bus, train, and flight for Greenville, SC to San Francisco, CA
Omio recommends booking the flight as it is the most popular option from Greenville, SC to San Francisco, CA among Omio's users. If you are prioritising price, take the bus, with an average ticket price of €300 For those with little time, consider booking a flight, which has an average total journey time of 9h 30m. Average ticket prices depend on the travel mode: a bus costs an average of €300, while a flight costs an average of €667.
Distance: 2220 miles (3574 km)
Compare flight with
Most popular Flight | Bus | Driving |
|---|---|---|
€667 Average price | €300 Average price Cheapest | €442 Average price (fuel + tolls) |
9h 30m Average total duration Fastest 7h 30m Onboard + 2h 0m Additional time* | 61h 21m Average total duration 60h 51m Onboard + 30m Additional time* | 38h 20m Average total duration (door-to-door) |
 Most popular airline |  Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
The cheapest way to travel from Greenville, SC to San Francisco, CA is a bus with an average price of €300.
This is compared to other travel options from Greenville, SC to San Francisco, CA:
A bus is €367 less than a flight for this route with tickets for a flight from Greenville, SC to San Francisco, CA costing on average €667.
The fastest way to travel from Greenville, SC to San Francisco, CA is by flight with an average journey time of 7h 30m.
Other travel options to San Francisco, CA take longer:
Bus takes on average 60h 51m.
It's helpful to compare your options as there are 3 ways to travel between Greenville, SC and San Francisco, CA including taking a bus, train, and flight.
We recommend using the flight as it is the most popular way to get from Greenville, SC to San Francisco, CA among Omio's users.
Live departures
Greenville, SC to San Francisco, CA train times
The table below shows live departures for Greenville, SC to San Francisco, CA trains for tomorrow, Saturday, September 19. You can also manually refresh the results below to see updated train journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| 6:23 AM Greenville, SC | 90h22 | 12:45 AM San Francisco, CA | 0 transfersDirect | |
| 7:23 AM Greenville, SC | 89h22 | 12:45 AM San Francisco, CA | 0 transfersDirect | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Greenville, SC to San Francisco, CA by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Train from Greenville, SC to San Francisco, CA
USAUSA
Take a train from Greenville, SC to San Francisco, CA and enjoy the approximately 2220 miles (3574 km) long journey. Find schedules and pricing options for a convenient and affordable trip.
The earliest train runs at 07:00, the last at 08:25.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from €156
Distance 2220 miles (3574 km) |
First train 7:00 AM |
Last train 8:25 AM |
Cheapest Month Oct |
Cheapest Day Mon |
High Season Apr - Jun |
Low Season Oct - Dec |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from €156
Complete guide to San Francisco, CA
Things to do in San Francisco, CA
Discover the best of San Francisco, CA — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect San Francisco, CA trip today.
- Must visit
de Young Museum
Major fine arts museum in Golden Gate Park with American art, textiles, and a panoramic tower. A classic cultural highlight.
- Must visit
San Francisco Museum of Modern Art
Leading modern and contemporary art museum with landmark architecture and strong global collections. Essential for art-focused visitors.
- Must visit
Golden Gate Park
Large urban park with gardens, lakes, museums, and trails. It is a must for relaxing, walking, and seeing several major attractions.
- Must visit
Lombard Street
Steeply curving block lined with flowers and grand homes. This famous street offers classic photos and a quintessential San Francisco scene.
- Must visit
The Embarcadero
Popular waterfront promenade with bay views, piers, and ferries. Great for walking, people-watching, and connecting to nearby sights.
- Vegetarian
- Vegan
San Francisco Sourdough
A crusty loaf with a tangy flavor shaped by the city’s historic wild yeast culture. It is one of San Francisco’s most iconic foods.
- Gluten-free
Dungeness Crab
Fresh local Dungeness crab, often cracked and served simply or in cioppino. It is a Bay Area seasonal specialty tied to the fishing waterfront.
Cioppino
A tomato-based seafood stew created by Italian American fishermen in North Beach. It is a classic San Francisco dish built from the day’s catch.
Benu
Celebrated fine dining destination known for inventive tasting menus and polished service in an elegant, intimate setting.
Sotto Mare
Historic North Beach seafood house famous for cioppino, crab, and old-school San Francisco waterfront charm.
La Taqueria
Legendary Mission taqueria known for large Mission-style burritos and a lively, no-frills local atmosphere.
US Dollar ($)
Very high hotel, dining, and transport costs make San Francisco pricier than most US cities and many major tourist destinations.
Average meal costs
- Budget
- $12-20 for fast food or casual takeout.
- Mid-range
- $25-45 per person for a restaurant meal.
- Fine dining
- $90+ per person for upscale dining.
- Coffee
- $4-7 for coffee or cappuccino.
Tipping culture
Tip 18-20% at restaurants, 15-20% for taxis, and round up or tip $1 at cafes for good service.
FAQs: Trains from Greenville, SC to San Francisco, CA
Find answers to the most common questions about traveling from Greenville, SC to San Francisco, CA by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at San Francisco, CA, this guide helps you travel smarter and with confidence.
The distance by train from Greenville, SC to San Francisco, CA is 2220 miles (3574 km).
The first train from Greenville, SC to San Francisco, CA leaves at 7:00 AM.
The last train from Greenville, SC to San Francisco, CA leaves at 8:25 AM.
Unfortunately, there is no night train available from Greenville, SC to San Francisco, CA.
The train station in Greenville, SC that goes to San Francisco, CA is Greenville Station, Greenville, SC, which connects to Emeryville station, Emeryville, CA.
The cheapest way to get from Greenville, SC to San Francisco, CA is by flight, with a cost of around €156.
The train journey from Greenville, SC to San Francisco, CA offers scenic views, especially as it passes through diverse landscapes including the rolling hills of the Appalachians, expansive plains, and the dramatic Sierra Nevada mountains before reaching the California coastline.
In San Francisco, CA, you can ride a cable car through steep streets, explore vibrant murals in the Mission District, and visit the Exploratorium, an interactive science museum. Take a scenic walk along the Embarcadero for views of the Bay Bridge and access to the Ferry Building Marketplace. Enjoy a wine tasting tour in nearby Napa Valley. Key sights include the Golden Gate Bridge, Alcatraz Island, Fisherman's Wharf, Golden Gate Park, and Chinatown, each offering unique experiences from panoramic views to vibrant culture and cuisine.
Three to four days in San Francisco, CA, allows you to explore major attractions like the Golden Gate Bridge, Alcatraz Island, Fisherman's Wharf, and neighborhoods like Chinatown and Haight-Ashbury, while also enjoying some of the city's renowned dining and cultural experiences.
No, you cannot take the train from Greenville, SC to San Francisco, CA.
Since neither Greenville, SC nor San Francisco, CA are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
Popular day trips by train from San Francisco, CA include Davis, CA, San Jose, CA, Stockton, CA, Santa Clara, CA, West Sacramento, CA.
We recommend using the bus as it is the most popular way to get from Greenville, SC to San Francisco, CA among Omio's users.
Items not allowed on trains typically include hazardous materials such as explosives, flammable liquids, corrosive substances, and illegal drugs. Additionally, large or bulky items that may obstruct aisles or emergency exits, as well as pets without proper carriers, may be restricted. Specific prohibited items can vary by train operator and region, so please check the rules for your particular journey.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In San Francisco, travelers should be cautious of pickpocketing and petty theft, especially in crowded areas like Fisherman's Wharf and Union Square. Common scams include distraction techniques used by groups to steal wallets and fake charity solicitations. It's advisable to avoid poorly lit or isolated areas at night and be wary of unofficial taxi services to ensure safety.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular train stations
Popular train stations from Greenville, SC to San Francisco, CA
Most Greenville, SC to San Francisco, CA trains use the Greenville Station to Emeryville Station station pair. Use this guide to compare Greenville, SC and San Francisco, CA train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Departure train stations in Greenville
Arrival train stations in San Francisco
Which Greenville, SC station do trains to San Francisco, CA leave from?
Trains from Greenville, SC to San Francisco, CA leave from Greenville Station. The station is 1 miles (2 km) from Greenville, SC city centre at 1120 West Washington Street, Greenville, SC 29601, USA.
Greenville Station1120 West Washington Street, Greenville, SC 29601, USA1-800-USA-RAIL
City-centre transport
Getting to Greenville Station from Greenville city centre
Greenville Station is 1 km from Greenville city centre. Public transport options include:
Bus503 · 5m · €1 · every ~2 min
Greenville Station train station facilities and services
Greenville Station has practical services for this route, including Wifi, Lockers, Parking, Dining, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Information Desk, and Luggage Carts.
Food and drink
Food options include: Soby's, Larkin's on the River
Wi-Fi and ATMs
Free.
Tickets and information
Ticket office support is available at Greenville Station. Information desks are located in the main hall.
Luggage and lost property
Luggage storage is available at Greenville Station. Lost and found is available at the station.
Parking, taxis and toilets
Available at Greenville Station: Parking, Taxis, WC.
Bike and car services
Available at Greenville Station: Bike Parking, Bike Rental.
Accessibility
Accessibility facilities are available at Greenville Station: Ramps, assistance.
Shops, hotels and contact
Nearby hotels include The Westin Poinsett, Greenville, Courtyard Greenville Downtown, Hyatt Regency Greenville.
Most popular train connections from Greenville, SC
More options for your journey from Greenville, SC to San Francisco, CA
Here are some other resources that might have the information you need
Most popular trains to and from San Francisco, CA and Greenville, SC
Most popular train connections to San Francisco, CA
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