- Must visit
Santa Maria della Scala
A vast former hospital complex opposite the cathedral, now a museum center with archaeological finds, frescoed halls, and temporary exhibitions. One of Siena’s richest cultural sites.
Cheapest price
$32
Average price
$47
Fastest journey
3 h 50 m
Average duration
4 h 12 m
Trains per day
17
Distance
227 km
The best way to find a cheap train ticket from Genoa to Siena is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Genoa to Siena will cost around $47 if you buy it on the day, but the cheapest tickets can be found for only $32.
It's difficult to get from Genoa to Siena without transferring at least 2 times.
Regionale 12381 · Regionale 18401 · Regionale 18225
Regionale 12411 · Regionale 18407 · Regionale 18233
Intercity 657+
Regionale 18413 · Regionale 18217
Intercity 665+
Regionale 18399 · Regionale 18223
Intercity 511+
Regionale Veloce 4040 · Regionale 19049
FRECCIARGENTO 8583+
Regionale 18425 · Regionale 18203
FRECCIABIANCA 8613+
Regionale Veloce 4038 · Regionale 19047
FRECCIAROSSA 8623+
Regionale Veloce 4058 · Regionale 19055
Intercity 505+
Regionale Veloce 4030 · Regionale 19039
FRECCIABIANCA 8619+
Regionale Veloce 4046 · Regionale 19051Omio recommends booking the bus as it is the most popular option from Genoa to Siena among Omio's users. If you are prioritising price take the bus with prices starting from $14. For those with little time consider booking a train which can get you there in 4h 21m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.2kg. The ticket price range depends on the travel mode: a bus costs an average of $14, and a train costs an average of $28.
Distance: 141 miles (227 km)
| Train | Most popular Bus | Driving |
|---|---|---|
$34 Average price | $22 Average price Cheapest | $82 Average price (fuel + tolls) |
4h 51m Average total duration Fastest 4h 21m Onboard + 30m Additional time* | 5h 0m Average total duration 4h 30m Onboard + 30m Additional time* | 3h 22m Average total duration (door-to-door) |
0.1 - 0.2kg CO2 emissions Lowest | 0.2 - 0.6kg CO2 emissions | - CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Genoa to Siena:
A bus is $12 (€10) less than a train for this route with tickets for a train from Genoa to Siena costing on average $34 (€28).
Other travel options to Siena take longer:
Bus takes on average 4h 30m.
Tickets start at around $34 (€28) compared to roughly $82 (€67) in fuel and tolls — a saving of about $48 (€39). The journey takes 4h 21m versus 3h 22m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
The table below shows live departures for Genoa to Siena trains for today, Tuesday, June 9. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FRECCIABIANCA 8613+ Regionale Veloce 4038 · Regionale 19047 | 12:05 PM Genoa Piazza Principe | 4h09 | 4:14 PM Siena station | 2 transfers | |
FRECCIABIANCA 8613+ Regionale 19126 | 12:05 PM Genoa Piazza Principe | 6h08 | 6:13 PM Siena station | 1 transfer | |
Intercity 511+ Regionale Veloce 4040 · Regionale 19049 | 12:24 PM Genoa Piazza Principe | 4h50 | 5:14 PM Siena station | 2 transfers | |
Regionale 12381 · Regionale 18401 · Regionale 18225 | 1:13 PM Genoa Piazza Principe | 6h25 | 7:38 PM Siena station | 2 transfers | |
Intercity 665+ Regionale 18399 · Regionale 18223 | 1:47 PM Genoa Piazza Principe | 4h53 | 6:40 PM Siena station | 2 transfers | |
FRECCIABIANCA 8619+ Regionale Veloce 4046 · Regionale 19051 | 2:50 PM Genoa Piazza Principe | 4h26 | 7:16 PM Siena station | 2 transfers | |
Intercity 669+ Regionale Veloce 4052 · Regionale 19053 | 3:47 PM Genoa Piazza Principe | 4h29 | 8:16 PM Siena station | 2 transfers | |
Regionale 12411 · Regionale 18407 · Regionale 18233 | 4:10 PM Genoa Piazza Principe | 7h06 | 11:16 PM Siena station | 2 transfers | |
FRECCIAROSSA 8623+ Regionale Veloce 4058 · Regionale 19055 | 5:05 PM Genoa Piazza Principe | 4h11 | 9:16 PM Siena station | 2 transfers | |
Intercity 673+ Regionale Veloce 4060 · Regionale 18233 | 5:47 PM Genoa Piazza Principe | 5h29 | 11:16 PM Siena station | 2 transfers | |
FRECCIARGENTO 8591+ Regionale Veloce 4062 · Regionale 18233 | 6:35 PM Genoa Piazza Principe | 4h41 | 11:16 PM Siena station | 2 transfers | |
InterCityNotte 899+ Regionale 19112 | 10:07 PM Genoa Piazza Principe | 9h44 | 7:51 AM Siena station | 1 transfer | |
| Wednesday, June 10 | |||||
FRECCIARGENTO 8583+ Regionale 18425 · Regionale 18203 | 5:48 AM Genoa Piazza Principe | 3h50 | 9:38 AM Siena station | 2 transfers | |
FRECCIARGENTO 8551+ Regionale 18282 · Regionale 18207 | 7:05 AM Genoa Piazza Principe | 4h35 | 11:40 AM Siena station | 2 transfers | |
Intercity 651+ Regionale 18409 · Regionale 18209 | 7:47 AM Genoa Piazza Principe | 4h51 | 12:38 PM Siena station | 2 transfers | |
Intercity 505+ Regionale Veloce 4030 · Regionale 19039 | 8:53 AM Genoa Piazza Principe | 4h22 | 1:15 PM Siena station | 2 transfers | |
Intercity 505+ Regionale 19122 | 8:53 AM Genoa Piazza Principe | 6h37 | 3:30 PM Siena station | 1 transfer | |
Intercity 657+ Regionale 18413 · Regionale 18217 | 9:47 AM Genoa Piazza Principe | 5h50 | 3:37 PM Siena station | 2 transfers | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Trains from Genoa to Siena run on average 15 times per day, taking around 4h 21m. Cheap train tickets for this journey start at $28 (€23) but you can travel from only $14 (€11) by bus.
The earliest train runs at 00:02, the last at 23:53. The fastest train covers the 141 miles (227 km) distance in 4h 9m.
Distance 141 miles (227 km) |
Average train duration 4h 21m |
Cheapest ticket price $28 (€23) |
Trains per day 15 |
Fastest train 4h 9m |
First train 12:02 AM |
Last train 11:53 PM |
Cheapest Month Jan |
Cheapest Day Wed |
High Season Jul - Sep |
Low Season Oct - Dec |
Busiest Day Fri |
Least Busy Day Sat |
Best time to book 4 days |
Discover the best of Siena — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Siena trip today.
A vast former hospital complex opposite the cathedral, now a museum center with archaeological finds, frescoed halls, and temporary exhibitions. One of Siena’s richest cultural sites.
Siena’s civic museum inside Palazzo Pubblico, famous for Ambrogio Lorenzetti’s fresco cycle Allegory of Good and Bad Government and rooms tied to the city’s republican history.
The cathedral museum complex includes works linked to the Duomo, including sculpture, stained glass, and access to important cathedral-related spaces.
Siena’s shell-shaped central square is one of Italy’s most famous urban spaces, home to the Palio and essential for understanding the city’s civic identity.
A famous panoramic terrace in the unfinished cathedral extension, popular for skyline photos and increasingly prominent on social media.
This elevated panorama over Siena’s rooftops and countryside is especially sought out for sunset photos and dramatic views over the cathedral area.
Thick hand-rolled pasta from southern Tuscany, usually served with a garlicky tomato sauce made with aglione, a local mild garlic. It is one of the most emblematic pasta dishes around Siena.
A traditional Tuscan bread and vegetable soup, typically made with beans, cavolo nero, and stale bread, then reheated to deepen the flavor. It is a classic rustic dish eaten across Siena.
A thick tomato and bread soup with olive oil, garlic, and basil. It is a simple but beloved Tuscan staple that showcases the region's bread-based cucina povera tradition.
Well-known traditional restaurant in a historic setting, celebrated for Tuscan classics, pasta, and meat dishes, with a warm and refined atmosphere.
Established upscale dining room near the center, known for elegant Tuscan cuisine, seasonal ingredients, and polished service in a classic Sienese setting.
Long-running central restaurant appreciated for honest Tuscan cooking, generous portions, and a simple local feel. A solid choice for classic Sienese fare.
Moderate by Italian standards. Historic-center dining costs more, but cafes, bakeries, and simple trattorias can be good value.
Service is often included or covered by coperto. Tipping is not required, but rounding up or leaving 5-10% for very good restaurant service is appreciated. Small change for taxis is enough.
Official public transport app
Siena Railway Station -> Piazza del Campo, Siena
Find answers to the most common questions about traveling from Genoa to Siena by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Siena, this guide helps you travel smarter and with confidence.

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