- Must visit
Santa Maria della Scala
A vast former hospital complex opposite the cathedral, now a museum center with archaeological finds, frescoed halls, and temporary exhibitions. One of Siena’s richest cultural sites.
Cheapest price
$40
Average price
$82
Fastest journey
4 h 53 m
Average duration
4 h 57 m
Trains per day
27
Distance
366 km
The best way to find a cheap train ticket from Naples Centrale to Siena is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Naples Centrale to Siena will cost around $82 if you buy it on the day, but the cheapest tickets can be found for only $40.
It's difficult to get from Naples Centrale to Siena without transferring at least once.
Regionale 21058 · Regionale Veloce 4098 · Regionale 19082
Regionale 21084 · Regionale Veloce 4106 · Regionale 19096
Regionale 21062 · Regionale Veloce 4128 · Regionale 19122
Regionale 21070 · Regionale Veloce 4136 · Autobus FI120
Regionale 21068 · Regionale Veloce 34476 · Regionale 19126
FRECCIAROSSA 9520+
Regionale 18209
FRECCIAROSSA 9532+
Regionale 18217
FRECCIAROSSA 9588+
Regionale 18225
FRECCIAROSSA 9556+
Regionale 18229
FRECCIAROSSA 9524+
Regionale 18213Omio recommends booking the train as it is the most popular option from Naples Centrale to Siena among Omio's users. If you are prioritising price take the bus with prices starting from $9. For those with little time consider booking a train which can get you there in 4h 54m. The ticket price range depends on the travel mode: a bus costs an average of $9, and a flight costs an average of $174.
Distance: 227 miles (366 km)
Most popular Train | Bus | Flight | Driving |
|---|---|---|---|
$42 Average price | $17 Average price Cheapest | $174 Average price | $123 Average price (fuel + tolls) |
5h 24m Average total duration Fastest 4h 54m Onboard + 30m Additional time* | 5h 58m Average total duration 5h 28m Onboard + 30m Additional time* | 13h 13m Average total duration 10h 13m Onboard + 3h 0m Additional time* | 4h 7m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Naples Centrale to Siena:
A bus is $25 (€20) less than a train for this route with tickets for a train from Naples Centrale to Siena costing on average $42 (€34).
A bus is $158 (€128) less than a flight for this route with tickets for a flight from Naples Centrale to Siena costing on average $174 (€142).
Other travel options to Siena take longer:
Bus takes on average 5h 28m.
Flight takes on average 10h 13m.
Tickets start at around {cheapestPrice} compared to roughly {drivingPriceInCents} in fuel and tolls — a saving of about {savingsAmount}. The journey takes {durationInMinutes} versus {drivingDurationInMinutes} by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Direct services run with Italo.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
The table below shows live departures for Naples Centrale to Siena trains for today, Saturday, June 6. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 3:04 AM Naples Centrale | 10h18 | 1:22 PM Siena | 0 transfersDirect | |
![]() | 3:55 AM Naples Centrale | 10h35 | 2:30 PM Siena | 0 transfersDirect | |
![]() | 4:09 AM Naples Centrale | 10h13 | 2:22 PM Siena | 0 transfersDirect | |
![]() | 8:26 AM Naples Centrale | 7h26 | 3:52 PM Siena | 0 transfersDirect | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Trains from Naples Centrale to Siena run on average 26 times per day, taking around 4h 54m. Cheap train tickets for this journey start at $26 (€21) but you can travel from only $9 (€7) by bus.
The earliest train runs at 02:55, the last at 19:38. The fastest train covers the 227 miles (366 km) distance in 3h 3m.
Distance 227 miles (366 km) |
Average train duration 4h 54m |
Cheapest ticket price $26 (€21) |
Trains per day 26 |
Fastest train 3h 3m |
First train 2:55 AM |
Last train 7:38 PM |
Cheapest Month Sep |
Cheapest Day Tue |
High Season Apr - Jun |
Low Season Oct - Dec |
Busiest Day Thu |
Least Busy Day Fri |
Discover the best of Siena — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Siena trip today.
A vast former hospital complex opposite the cathedral, now a museum center with archaeological finds, frescoed halls, and temporary exhibitions. One of Siena’s richest cultural sites.
Siena’s civic museum inside Palazzo Pubblico, famous for Ambrogio Lorenzetti’s fresco cycle Allegory of Good and Bad Government and rooms tied to the city’s republican history.
The cathedral museum complex includes works linked to the Duomo, including sculpture, stained glass, and access to important cathedral-related spaces.
Siena’s shell-shaped central square is one of Italy’s most famous urban spaces, home to the Palio and essential for understanding the city’s civic identity.
A famous panoramic terrace in the unfinished cathedral extension, popular for skyline photos and increasingly prominent on social media.
This elevated panorama over Siena’s rooftops and countryside is especially sought out for sunset photos and dramatic views over the cathedral area.
Thick hand-rolled pasta from southern Tuscany, usually served with a garlicky tomato sauce made with aglione, a local mild garlic. It is one of the most emblematic pasta dishes around Siena.
A traditional Tuscan bread and vegetable soup, typically made with beans, cavolo nero, and stale bread, then reheated to deepen the flavor. It is a classic rustic dish eaten across Siena.
A thick tomato and bread soup with olive oil, garlic, and basil. It is a simple but beloved Tuscan staple that showcases the region's bread-based cucina povera tradition.
Well-known traditional restaurant in a historic setting, celebrated for Tuscan classics, pasta, and meat dishes, with a warm and refined atmosphere.
Established upscale dining room near the center, known for elegant Tuscan cuisine, seasonal ingredients, and polished service in a classic Sienese setting.
Long-running central restaurant appreciated for honest Tuscan cooking, generous portions, and a simple local feel. A solid choice for classic Sienese fare.
Moderate by Italian standards. Historic-center dining costs more, but cafes, bakeries, and simple trattorias can be good value.
Service is often included or covered by coperto. Tipping is not required, but rounding up or leaving 5-10% for very good restaurant service is appreciated. Small change for taxis is enough.
Official public transport app
Siena Railway Station -> Piazza del Campo, Siena
Find answers to the most common questions about traveling from Naples Centrale to Siena by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Siena, this guide helps you travel smarter and with confidence.

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