- Must visit
National Museum
Major museum of Czech history and natural sciences in a monumental Neo-Renaissance building overlooking Wenceslas Square.
The best way to find a cheap train ticket from Enschede to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Enschede to Prague will cost around €175 if you buy it on the day, but the cheapest tickets can be found for only €105.
It's difficult to get from Enschede to Prague without transferring at least 2 times.
RE RS23 · ICE 243 · ICE 619 · EC 459
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RE RS23 · ICE 149 · IC 2045 · S1
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RE RS23 · ICE 145 · RJ 385
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RE RS23 · ICE 143 · ICE 587 · 3573
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RE RS23 · ICE 241 · ICE 905 · 16501
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R 7942 · ICE 145 · rj 385
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RE RS23 · ICE 145 · RJ 385
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RE RS23 · ICE 147 · RJ 179
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RE RS23 · ICE 143 · ICE 587 · 3573
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R 20257 · IC 2441 · S 31751 · Os 28012
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Trains from Enschede to Prague run on average 7 times per day, taking around 8h 53m. Cheap train tickets for this journey start at €45 but you can travel from only €25 by bus.
The earliest train runs at 03:08, the last at 23:54. The fastest train covers the 357 miles (575 km) distance in 7h 44m.
Distance 357 miles (575 km) |
Average train duration 8h 53m |
Cheapest ticket price €45 |
Trains per day 7 |
Fastest train 7h 44m |
First train 3:08 AM |
Last train 11:54 PM |
Cheapest Month Jul |
Cheapest Day Tue |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Mon |
Least Busy Day Wed |
Best time to book 1 day |
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Enschede to Prague.
The table below shows live departures for Enschede to Prague trains for today, Sunday, November 1. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
R 20269 · IC 2045 · S 31775 · Os 28023 | 2:03 PM Enschede station | 16h07 | 6:10 AM Prague hlavní nádraží | 4 transfers | |
RE RS23 · ICE 149 · IC 2045 · S1 | 3:34 PM Enschede station | 14h36 | 6:10 AM Prague hlavní nádraží | 5 transfers | |
RE RS23 · ICE 241 · ICE 905 · 16501 | 5:34 PM Enschede station | 15h36 | 9:10 AM Prague hlavní nádraží | 6 transfers | |
| Monday, November 2 | |||||
R 20257 · IC 2441 · S 31751 · Os 28012 | 8:03 AM Enschede station | 13h07 | 9:10 PM Prague hlavní nádraží | 4 transfers | |
RE RS23 · ICE 143 · ICE 587 · 3573 | 9:34 AM Enschede station | 10h47 | 8:21 PM Prague hlavní nádraží | 5 transfers | |
R 7942 · ICE 145 · rj 385 | 11:34 AM Enschede station | 9h51 | 9:25 PM Prague hlavní nádraží | 2 transfers | |
RE RS23 · ICE 145 · RJ 385 | On time 11:34 AM Enschede station | 9h51 | 9:25 PM Prague hlavní nádraží | 2 transfers | |
RE RS23 · ICE 147 · RJ 179 | On time 1:34 PM Enschede station | 9h57 | 11:31 PM Prague hlavní nádraží | 2 transfers | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
Discover the best of Prague — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Prague trip today.
Major museum of Czech history and natural sciences in a monumental Neo-Renaissance building overlooking Wenceslas Square.
Well-curated Jewish history museum across several historic sites. Important for understanding Prague's Jewish heritage and resilience.
Leading Czech art museum with medieval to modern works in a grand historic palace. Essential for fine art and decorative arts lovers.
Historic square at Prague's core, surrounded by Gothic and Baroque landmarks. A must for first-time visitors and classic city views.
Lively boulevard of Czech modern history, lined with shops and major buildings. Worth visiting for atmosphere and historic significance.
Romantic quarter of palaces, lanes, and church domes beneath Prague Castle. Ideal for wandering, photography, and quieter historic charm.
Slow-braised beef in a creamy root-vegetable sauce, usually served with bread dumplings. A classic Czech Sunday dish strongly linked to Bohemian home cooking.
Crisp roasted pork knuckle, often served with mustard, horseradish, and pickles. A hearty pub staple popular with Czech beer culture.
Roast pork with sauerkraut and dumplings. This iconic Czech combination is a cornerstone of traditional pub and family meals.
Traditional Czech restaurant and brewery by Prague Castle, praised for roast meats, dumplings, and polished historic interiors.
Upscale restaurant focused on Czech ingredients and game, with sophisticated service in an Art Nouveau municipal house setting.
Elegant Michelin-starred restaurant known for modern Czech tasting menus in a refined setting near the Vltava.
Moderate for Europe: transit is cheap, casual meals are reasonable, and hotels in the center can raise daily costs in peak season.
Service is often not included. Tip about 5-10% in restaurants, round up for cafes, and round up or add about 10% for taxis if service is good.
Official public transport app
Praha hlavní nádraží -> Václavské náměstí, Prague
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Prague.
Find answers to the most common questions about traveling from Enschede to Prague by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

Most Enschede to Prague trains use the Enschede to Praha hlavní nádraží station pair, with some services arriving at Praha-Holesovice. Use this guide to compare Enschede and Prague train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Enschede has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Car Rental, Information Desk, and Luggage Carts.
Food options include: Restaurant Fellini Enschede, De Kater
Free. ATMs are available in the train station.
Ticket office support is available at Enschede. Information desks are located in the main hall.
Luggage storage is available at Enschede. Lost and found is available at the station.
Available at Enschede: Parking, Taxis, WC.
Available at Enschede: Bike Parking, Car Rental.
Accessibility facilities are available at Enschede: Ramps, restrooms.
Nearby hotels include IntercityHotel Enschede, Van der Valk Hotel Enschede, U Parkhotel.
Enschede De Eschmarke is 3 km from Enschede city centre. Public transport options include:
Enschede De Eschmarke has practical services for this route, including Parking, Dining, Accessibility, and Bike Parking.
Food and drink options are available at Enschede De Eschmarke.
Available at Enschede De Eschmarke: Parking.
Available at Enschede De Eschmarke: Bike Parking.
Accessibility facilities are available at Enschede De Eschmarke.
Glanerbrug is 5 km from Enschede city centre. Public transport options include:
Glanerbrug has practical services for this route, including Parking, Dining, ATM, Accessibility, and Bike Parking.
Food and drink options are available at Glanerbrug.
ATMs are available at Glanerbrug.
Available at Glanerbrug: Parking.
Available at Glanerbrug: Bike Parking.
Accessibility facilities are available at Glanerbrug.
Praha hlavní nádraží is 1 km from Prague city centre. Public transport options include:
Praha hlavní nádraží has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Shower, Lounge, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, Information Desk, and Luggage Carts.
Food options include: Restaurant Fantova Kavárna, Sushi Time
Free. ATMs are available in the train station.
Ticket office support is available at Praha hlavní nádraží. Information desks are located in the main hall.
Luggage storage is available at Praha hlavní nádraží. Lost and found is available at the station.
Available at Praha hlavní nádraží: Parking, Taxis, WC.
Available at Praha hlavní nádraží: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Praha hlavní nádraží: Elevators, ramps.
Nearby hotels include Hotel Esplanade Prague, Falkensteiner Hotel Maria Prag, Hotel City Central.
Praha-Holesovice is 2 km from Prague city centre. Public transport options include:
Praha-Holesovice has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, Information Desk, and Luggage Carts.
Food options include: Restaurant Na Kovárně, Cross Club
Free. ATMs are available in the train station.
Ticket office support is available at Praha-Holesovice. Information desks are located in the main hall.
Luggage storage is available at Praha-Holesovice. Lost and found is available at the station.
Available at Praha-Holesovice: Parking, Taxis, WC.
Available at Praha-Holesovice: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Praha-Holesovice: Ramps, restrooms.
Nearby hotels include Mama Shelter Prague, Plaza Alta Hotel, Hotel Belvedere.
Check train stations information for Enschede and Prague, including where trains depart and arrive on this route.
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