- Must visit
Pinacoteca di Brera
One of Italy’s top art museums, featuring masterpieces by Mantegna, Bellini, Raphael, Caravaggio, and Piero della Francesca.
Omio recommends booking the flight as it is the most popular option from Enschede to Milan among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $131 For those with little time, consider booking a flight, which has an average total journey time of 5h 9m. Average ticket prices depend on the travel mode: a bus costs an average of $131, while a flight costs an average of $601.
Distance: 477 miles (769 km)
| Train | Most popular Flight | Bus |
|---|---|---|
$601 Average price | $131 Average price Cheapest | |
5h 9m Average total duration Fastest 3h 9m Onboard + 2h 0m Additional time* | 21h 50m Average total duration 21h 20m Onboard + 30m Additional time* | |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Enschede to Milan:
A bus is $470 (€384) less than a flight for this route with tickets for a flight from Enschede to Milan costing on average $601 (€491).
Other travel options to Milan take longer:
Bus takes on average 21h 20m.
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Take a train from Enschede to Milan and enjoy the approximately 477 miles (769 km) long journey. Find schedules and pricing options for a convenient and affordable trip.
The earliest train runs at 10:20, the last at 11:10.
Distance 477 miles (769 km) |
First train 10:20 AM |
Last train 11:10 AM |
High Season Apr - Jun |
Low Season Jul - Sep |
Busiest Day Wed |
Least Busy Day Sat |
Best time to book 35 days |
Discover the best of Milan — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Milan trip today.
One of Italy’s top art museums, featuring masterpieces by Mantegna, Bellini, Raphael, Caravaggio, and Piero della Francesca.
This contemporary art museum near Porta Romana presents rotating exhibitions in a striking former industrial distillery complex.
Italy’s leading science museum is set in a former monastery and features Leonardo galleries, trains, aircraft, and a submarine.
Milan’s central square frames the cathedral and major civic buildings, making it the city’s essential meeting point and photo stop.
This artistic district offers charming lanes, Brera atmosphere, boutiques, and easy access to galleries and evening strolls.
A large landscaped park behind the castle, perfect for walks, skyline views, and reaching landmarks like the Arch of Peace.
Saffron risotto cooked with butter, stock and cheese. It is Milan's signature dish, linked to the city's love of rich northern Italian rice cookery.
Breaded veal cutlet fried in butter until golden. A classic Milanese main, prized for its simple preparation and long-standing local tradition.
Slow-braised veal shanks with vegetables, wine and broth, often finished with gremolata. A hearty Lombard specialty commonly paired with risotto.
Three-Michelin-star fine dining by Enrico Bartolini in MUDEC. Expect refined Italian tasting menus in a polished contemporary setting.
Historic Milanese restaurant near the Duomo, famous for risotto and cotoletta. Traditional, elegant rooms and a strong local culinary identity.
Long-running local favorite for classic Milanese cuisine, especially risotto and ossobuco. Warm, old-school atmosphere in the Brera area.
Moderate for Western Europe. Hotels and central dining can be pricey, but transit is affordable and budget meals, aperitivo deals, and local cafes help keep daily costs reasonable.
Tipping is modest. Service may be included. Round up or leave €1-2 at cafes, 5-10% for good restaurant service, and round up taxi fares.
Official public transport app
Milan Centrale -> Piazza del Duomo
Find answers to the most common questions about traveling from Enschede to Milan by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Milan, this guide helps you travel smarter and with confidence.

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