The cheapest and fastest trains from Venice Mestre to Florence Santa Maria Novella
Cheapest price
$27
Average price
$54
Fastest journey
1 h 59 m
Average duration
2 h
Trains per day
47
Distance
205 km
The best way to find a cheap train ticket from Venice Mestre to Florence Santa Maria Novella is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Venice Mestre to Florence Santa Maria Novella will cost around $54 if you buy it on the day, but the cheapest tickets can be found for only $27.
Of the 47 trains that leave Venice Mestre for Florence Santa Maria Novella on Fri, May 08, 27 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Fri, May 08 the direct trains cover the 205 km distance in an average of 2 h but if you time it right, some trains will get you there in just 1 h 59 m .
On Fri, May 08 the slowest trains will take 2 h 1 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
Regionale Veloce 3985 · Regionale 178515:53 PM4h17Venice Mestre10:10 PMFlorence Santa Maria Novella$271One-way1 transfer
Regionale Veloce 3983 · Regionale TTPER 17847 · Regionale 178514:53 PM5h17Venice Mestre10:10 PMFlorence Santa Maria Novella$271One-way2 transfers
Regionale Veloce 3987 · Regionale 17853 · Regionale 185396:53 PM4h57Venice Mestre11:50 PMFlorence Santa Maria Novella$271One-way2 transfers
Regionale Veloce 3965 · Autobus TTPER B0403 · Regionale 186737:53 AM5h21Venice Mestre1:14 PMFlorence Santa Maria Novella$271One-way2 transfers
Regionale Veloce 3975 · Regionale 17833 · Regionale 1852112:53 PM3h59Venice Mestre4:52 PMFlorence Santa Maria Novella$271One-way2 transfers
FRECCIAROSSA 94098:40 AM1h59Venice Mestre10:39 AMFlorence Santa Maria Novella$1021One-way0 transfers
89079:20 AM2h00Venice Mestre11:20 AMFlorence Santa Maria Novella$701One-way0 transfers
FRECCIAROSSA 94036:38 AM2h01Venice Mestre8:39 AMFlorence Santa Maria Novella$741One-way0 transfers
FRECCIAROSSA 94252:38 PM2h01Venice Mestre4:39 PMFlorence Santa Maria Novella$741One-way0 transfers
FRECCIAROSSA 94057:38 AM2h01Venice Mestre9:39 AMFlorence Santa Maria Novella$741One-way0 transfers
Travel Information
Compare train and bus for Venice Mestre to Florence Santa Maria Novella
Omio recommends booking the train as it is the most popular option from Venice Mestre to Florence Santa Maria Novella among Omio's users. If you are prioritising price take the bus with prices starting from $9. For those with little time consider booking a train which can get you there in 3h 26m. The ticket price range depends on the travel mode: a bus costs an average of $9, and a train costs an average of $26.
Distance: 127 miles (205 km)
Compare train with
Most popular Train | Bus | Driving |
|---|---|---|
$46 Average price | $23 Average price Cheapest | $78 Average price (fuel + tolls) |
3h 56m Average total duration Fastest 3h 26m Onboard + 30m Additional time* | 4h 27m Average total duration 3h 57m Onboard + 30m Additional time* | 2h 56m Average total duration (door-to-door) |
![]() Most popular train company | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Venice Mestre to Florence Santa Maria Novella:
A bus is $23 (€18) less than a train for this route with tickets for a train from Venice Mestre to Florence Santa Maria Novella costing on average $46 (€37).
Other travel options to Florence Santa Maria Novella take longer:
Bus takes on average 3h 57m.
Tickets start at around {cheapestPrice} compared to roughly {drivingPriceInCents} in fuel and tolls — a saving of about {savingsAmount}. The journey takes {durationInMinutes} versus {drivingDurationInMinutes} by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Direct services run with Italo, Frecciarossa.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
Live departures
Venice Mestre to Florence Santa Maria Novella train times
The table below shows live departures for Venice Mestre to Florence Santa Maria Novella trains for today, Thursday, May 7. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
8929 | Delayed 10:18 AM 12:17 PMVenice Mestre | 2h03 | 12:21 PM 12:21 PMFlorence Santa Maria Novella | 0 transfersDirect | |
FRECCIAROSSA 8419 | 12:38 PM Venice Mestre | 2h01 | 2:39 PM Florence Santa Maria Novella | 0 transfersDirect | |
Regionale Veloce 3975 · Regionale 17833 · Regionale 18521 | 12:53 PM Venice Mestre | 3h59 | 4:52 PM Florence Santa Maria Novella | 2 transfers | |
Intercity 584+ Regionale Veloce 4042 | 1:05 PM Venice Mestre | 3h28 | 4:33 PM Florence Santa Maria Novella | 1 transfer | |
8913 | On time 1:17 PM Venice Mestre | 2h03 | 3:20 PM Florence Santa Maria Novella | 0 transfersDirect | |
FRECCIAROSSA 9421 | 1:38 PM Venice Mestre | 2h01 | 3:39 PM Florence Santa Maria Novella | 0 transfersDirect | |
Regionale Veloce 3977 · Regionale 17837 · Regionale 18525 | 1:53 PM Venice Mestre | 3h59 | 5:52 PM Florence Santa Maria Novella | 2 transfers | |
Regionale Veloce 3977+ Intercity 597+ Regionale 18232 | 1:53 PM Venice Mestre | 3h59 | 5:52 PM Florence Santa Maria Novella | 2 transfers | |
8915 | On time 2:17 PM Venice Mestre | 2h03 | 4:20 PM Florence Santa Maria Novella | 0 transfersDirect | |
FRECCIAROSSA 9425 | 2:38 PM Venice Mestre | 2h01 | 4:39 PM Florence Santa Maria Novella | 0 transfersDirect | |
Regionale Veloce 3979 · Regionale 17839 · Regionale 18527 | 2:53 PM Venice Mestre | 3h59 | 6:52 PM Florence Santa Maria Novella | 2 transfers | |
8919 | On time 3:17 PM Venice Mestre | 2h03 | 5:20 PM Florence Santa Maria Novella | 0 transfersDirect | |
Intercity 594+ Regionale 18312 | 3:34 PM Venice Mestre | 3h09 | 6:43 PM Florence Santa Maria Novella | 1 transfer | |
FRECCIAROSSA 9427 | 3:38 PM Venice Mestre | 2h01 | 5:39 PM Florence Santa Maria Novella | 0 transfersDirect | |
Regionale Veloce 3981 · Regionale 17843 · Regionale 18529 | 3:53 PM Venice Mestre | 3h59 | 7:52 PM Florence Santa Maria Novella | 2 transfers | |
8923 | On time 4:17 PM Venice Mestre | 2h03 | 6:20 PM Florence Santa Maria Novella | 0 transfersDirect | |
FRECCIAROSSA 9431 | 4:38 PM Venice Mestre | 2h01 | 6:39 PM Florence Santa Maria Novella | 0 transfersDirect | |
Regionale Veloce 3983 · Regionale TTPER 17847 · Regionale 18531 | 4:53 PM Venice Mestre | 3h59 | 8:52 PM Florence Santa Maria Novella | 2 transfers | |
8925 | 5:17 PM Venice Mestre | 2h03 | 7:20 PM Florence Santa Maria Novella | 0 transfersDirect | |
FRECCIAROSSA 9433 | 5:38 PM Venice Mestre | 2h01 | 7:39 PM Florence Santa Maria Novella | 0 transfersDirect | |
Regionale Veloce 3985+ Intercity 599 | 5:53 PM Venice Mestre | 3h29 | 9:22 PM Florence Santa Maria Novella | 1 transfer | |
Regionale Veloce 3985 · Regionale 17851 | 5:53 PM Venice Mestre | 4h17 | 10:10 PM Florence Santa Maria Novella | 1 transfer | |
8927 | On time 6:17 PM Venice Mestre | 2h03 | 8:20 PM Florence Santa Maria Novella | 0 transfersDirect | |
FRECCIAROSSA 9435 | 6:38 PM Venice Mestre | 2h01 | 8:39 PM Florence Santa Maria Novella | 0 transfersDirect | |
FRECCIAROSSA 9437 | 7:38 PM Venice Mestre | 2h01 | 9:39 PM Florence Santa Maria Novella | 0 transfersDirect | |
Regionale Veloce 3989 · Regionale 17853 · Regionale 18539 | 7:53 PM Venice Mestre | 3h57 | 11:50 PM Florence Santa Maria Novella | 2 transfers | |
| Friday, May 8 | |||||
FRECCIAROSSA 9401 | 5:38 AM Venice Mestre | 2h01 | 7:39 AM Florence Santa Maria Novella | 0 transfersDirect | |
Regionale Veloce 3961 · Regionale 17813 · Regionale 18507 | 5:53 AM Venice Mestre | 3h59 | 9:52 AM Florence Santa Maria Novella | 2 transfers | |
FRECCIAROSSA 9403 | 6:38 AM Venice Mestre | 2h01 | 8:39 AM Florence Santa Maria Novella | 0 transfersDirect | |
Regionale Veloce 3963 · Autobus TTPER B0401 · Regionale 18489 | 6:53 AM Venice Mestre | 4h31 | 11:24 AM Florence Santa Maria Novella | 2 transfers | |
8903 | On time 7:17 AM Venice Mestre | 2h03 | 9:20 AM Florence Santa Maria Novella | 0 transfersDirect | |
FRECCIAROSSA 9405 | 7:38 AM Venice Mestre | 2h01 | 9:39 AM Florence Santa Maria Novella | 0 transfersDirect | |
Regionale Veloce 3965 · Autobus TTPER B0403 · Regionale 18673 | 7:53 AM Venice Mestre | 5h21 | 1:14 PM Florence Santa Maria Novella | 2 transfers | |
8905 | On time 8:17 AM Venice Mestre | 2h03 | 10:20 AM Florence Santa Maria Novella | 0 transfersDirect | |
FRECCIAROSSA 9409 | 8:40 AM Venice Mestre | 1h59 | 10:39 AM Florence Santa Maria Novella | 0 transfersDirect | |
Regionale Veloce 3967 · Autobus TTPER B0405 · Regionale 18515 | 8:53 AM Venice Mestre | 4h59 | 1:52 PM Florence Santa Maria Novella | 2 transfers | |
8907 | On time 9:20 AM Venice Mestre | 2h00 | 11:20 AM Florence Santa Maria Novella | 0 transfersDirect | |
FRECCIAROSSA 9411 | 9:38 AM Venice Mestre | 2h01 | 11:39 AM Florence Santa Maria Novella | 0 transfersDirect | |
Regionale Veloce 3997 · Autobus FI681 · Regionale 18473 | 9:53 AM Venice Mestre | 4h31 | 2:24 PM Florence Santa Maria Novella | 2 transfers | |
8902 | On time 10:17 AM Venice Mestre | 2h03 | 12:20 PM Florence Santa Maria Novella | 0 transfersDirect | |
FRECCIAROSSA 9413 | 10:38 AM Venice Mestre | 2h01 | 12:39 PM Florence Santa Maria Novella | 0 transfersDirect | |
Regionale Veloce 3971 · Regionale TTPER 17827 · Regionale 18517 | 10:53 AM Venice Mestre | 3h59 | 2:52 PM Florence Santa Maria Novella | 2 transfers | |
8911 | On time 11:17 AM Venice Mestre | 2h03 | 1:20 PM Florence Santa Maria Novella | 0 transfersDirect | |
FRECCIAROSSA 9415 | 11:38 AM Venice Mestre | 2h01 | 1:39 PM Florence Santa Maria Novella | 0 transfersDirect | |
Regionale Veloce 3973 · Regionale 17831 · Regionale 18519 | 11:53 AM Venice Mestre | 3h59 | 3:52 PM Florence Santa Maria Novella | 2 transfers | |
Find all the dates and times for this journey
Compare prices and tickets Venice Mestre to Florence Santa Maria Novella by train or bus
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
May 07
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May 27
Why should you book Venice Mestre to Florence Santa Maria Novella trains with Omio?
Why book with Omio vs Italo?
- Compare with other providers: On Omio, you can not only buy tickets for Italo, but also compare tickets for the likes of Frecciarossa, Regionale, Intercity or Intercity Notte to find the best option for your trip from Venice Mestre to Florence Santa Maria Novella.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Italo with all available travel options, which are train and bus to ensure you get the best deal for traveling from Venice Mestre to Florence Santa Maria Novella.
Journey information
Overview: Train from Venice Mestre to Florence Santa Maria Novella
Trains from Venice Mestre to Florence Santa Maria Novella run on average 24 times per day, taking around 3h 26m. Cheap train tickets for this journey start at $26 (€21) but you can travel from only $9 (€7) by bus.
There are 16 trains per day. The earliest train runs at 05:53, the last at 18:53. The fastest train covers the 127 miles (205 km) distance in 2h 0m.
Distance 127 miles (205 km) |
Average train duration 3h 26m |
Cheapest ticket price $26 (€21) |
Trains per day 24 |
Direct trains 16 |
Fastest train 2h 0m |
First train 5:53 AM |
Last train 6:53 PM |
Cheapest Month Sep |
Cheapest Day Fri |
High Season Apr - Jun |
Low Season Jan - Mar |
Busiest Day Mon |
Least Busy Day Thu |
Train companies: Italo, Frecciarossa, Regionale, Intercity, Intercity Notte from Venice Mestre to Florence Santa Maria Novella trainsItalo, Frecciarossa, Regionale, Intercity, Intercity Notte trains will get you between Venice Mestre and Florence Santa Maria Novella from $9 (€7). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Italo
Frecciarossa
Regionale
Intercity
Intercity Notte
FAQs: Trains from Venice Mestre to Florence Santa Maria Novella
Find answers to the most common questions about traveling from Venice Mestre to Florence Santa Maria Novella by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Florence Santa Maria Novella, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Venice Mestre to Florence Santa Maria Novella
- Mon - Sun: 05:50 - 20:30
- Provided by KiPoint and located on the ground floor.
- McDonald’s
- Chock Full O'Nuts
- Puro Gusto
- Juice Bar
- Rossosapore
- Full accessibility facilities, including toilets, ramps, wheelchairs, elevators and a mobility assistance center.
- Best Western Hotel Tritone
- The Plaza Hotel
- Hotel Villa Constanza
- Mon - Sun: 05:50 - 20:30
- Located in the main concourse.
- Bus lines: 2, 3, 10, 15, 18, 25a, 31, 31H, 32, 32H, 33H, 34H, 43, 53, 86, N1, 8AE
- Train lines: FR, FA, FB, EC, RJ, IC, EN, ICN, R, Italo
- Mon - Sun: 06:00 - 21:00
- Free WiFi (30 minutes limit).
- Provided by KiPoint and located on the ground floor, on the side of Piazza Adua. Open daily from 06:00 to 23:00.
- 12oz Coffee Joint
- Casa Maioli
- Don Nino
- Fratelli Cuore
- McDonald´s
- Panella
- Segafredo Zanetti
- Spizzico
- Venchi
- & many more
- Elevators, escalators, step-free access. Mobility assistance is available with the Sala Blu, located next to Platform 1.
- Hotel Luxor Florence
- Joy Hotel Florence
- Diplomat Hotel Florence
- Mon - Sun: 06:00 - 21:00
- Located inside and outside the station.
- Tram lines: T1, T2
- Bus lines: 6, 11, 12, 13, 17, 23, 36, 37, C4
- Train lines: FR, FA, Italo
Most popular train connections from Venice Mestre
More options for your journey from Venice Mestre to Florence Santa Maria Novella
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