The cheapest and fastest trains from Venice Mestre to Florence Santa Maria Novella
Cheapest price
$30
Average price
$66
Fastest journey
1 h 59 m
Average duration
2 h
Trains per day
45
Distance
205 km
The best way to find a cheap train ticket from Venice Mestre to Florence Santa Maria Novella is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Venice Mestre to Florence Santa Maria Novella will cost around $66 if you buy it on the day, but the cheapest tickets can be found for only $30.
Of the 45 trains that leave Venice Mestre for Florence Santa Maria Novella on Tue, Dec 23, 27 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Tue, Dec 23 the direct trains cover the 205 km distance in an average of 2 h but if you time it right, some trains will get you there in just 1 h 59 m .
On Tue, Dec 23 the slowest trains will take 2 h 1 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
Regionale Veloce 3979 · Regionale 17839 · Tuscany Line 18527
Regionale Veloce 3973 · Regionale 17831 · Tuscany Line 18519
Regionale Veloce 3961 · Regionale 17813 · TUSCANY LINE 18507
Regionale Veloce 3989 · Regionale 17853 · Tuscany Line 18539
Regionale Veloce 3963 · Autobus TTPER B0401 · TUSCANY LINE 18489
FRECCIAROSSA 1000 9409
8907
FRECCIAROSSA 1000 9437
FRECCIAROSSA 9405
FRECCIAROSSA 9401Venice Mestre - Florence Santa Maria NovellaCompare Italo, Frecciarossa, Regionale, Intercity, Intercity Notte





Travel Information
Compare bus and train for Venice Mestre to Florence Santa Maria Novella
Omio recommends booking the train as it is the most popular option from Venice Mestre to Florence Santa Maria Novella among Omio's users. If you are prioritising price take the bus with prices starting from €7. For those with little time consider booking a train which can get you there in 3h 25m. The ticket price range depends on the travel mode: a bus costs an average of €7, and a train costs an average of €21.
Distance: 127 miles (205 km)
Compare train with
Most popular Train | Bus |
|---|---|
€36 Average price | €21 Average price Cheapest |
3h 55m Average total duration Fastest 3h 25m Onboard + 30m Additional time* | 4h 25m Average total duration 3h 55m Onboard + 30m Additional time* |
![]() Most popular train company | ![]() Most popular bus company |
Direct Options | Direct Options |
Live departures
Venice Mestre to Florence Santa Maria Novella train times
The table below shows live departures for Venice Mestre to Florence Santa Maria Novella trains for tomorrow, Tuesday, December 23. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FRECCIAROSSA 9401 | 4:38 AM Venice Mestre | 2h01 | 6:39 AM Florence Santa Maria Novella | 0 transfersDirect | |
Regionale Veloce 3961 · Regionale 17813 · TUSCANY LINE 18507 | 4:53 AM Venice Mestre | 3h59 | 8:52 AM Florence Santa Maria Novella | 2 transfers | |
FRECCIAROSSA 9403 | 5:38 AM Venice Mestre | 2h01 | 7:39 AM Florence Santa Maria Novella | 0 transfersDirect | |
Regionale Veloce 3963 · Autobus TTPER B0401 · TUSCANY LINE 18489 | 5:53 AM Venice Mestre | 4h31 | 10:24 AM Florence Santa Maria Novella | 2 transfers | |
8903 | 6:17 AM Venice Mestre | 2h03 | 8:20 AM Florence Santa Maria Novella | 0 transfersDirect | |
FRECCIAROSSA 9405 | 6:38 AM Venice Mestre | 2h01 | 8:39 AM Florence Santa Maria Novella | 0 transfersDirect | |
Regionale Veloce 3965 · Autobus TTPER B0403 · Tuscany Line 18673 | 6:53 AM Venice Mestre | 5h21 | 12:14 PM Florence Santa Maria Novella | 2 transfers | |
8905 | On time 7:17 AM Venice Mestre | 2h03 | 9:20 AM Florence Santa Maria Novella | 0 transfersDirect | |
FRECCIAROSSA 1000 9409 | 7:40 AM Venice Mestre | 1h59 | 9:39 AM Florence Santa Maria Novella | 0 transfersDirect | |
Regionale Veloce 3967 · Autobus TTPER B0405 · TUSCANY LINE 18515 | 7:53 AM Venice Mestre | 4h59 | 12:52 PM Florence Santa Maria Novella | 2 transfers | |
8907 | 8:20 AM Venice Mestre | 2h00 | 10:20 AM Florence Santa Maria Novella | 0 transfersDirect | |
FRECCIAROSSA 1000 9411 | 8:38 AM Venice Mestre | 2h01 | 10:39 AM Florence Santa Maria Novella | 0 transfersDirect | |
Regionale Veloce 3997 · Autobus FI681 · Tuscany Line 18473 | 8:53 AM Venice Mestre | 4h31 | 1:24 PM Florence Santa Maria Novella | 2 transfers | |
8902 | 9:17 AM Venice Mestre | 2h03 | 11:20 AM Florence Santa Maria Novella | 0 transfersDirect | |
FRECCIAROSSA 1000 9413 | 9:38 AM Venice Mestre | 2h01 | 11:39 AM Florence Santa Maria Novella | 0 transfersDirect | |
Regionale Veloce 3971 · Regionale TTPER 17827 · Tuscany Line 18517 | 9:53 AM Venice Mestre | 3h59 | 1:52 PM Florence Santa Maria Novella | 2 transfers | |
8911 | On time 10:17 AM Venice Mestre | 2h03 | 12:20 PM Florence Santa Maria Novella | 0 transfersDirect | |
FRECCIAROSSA 1000 9415 | 10:38 AM Venice Mestre | 2h01 | 12:39 PM Florence Santa Maria Novella | 0 transfersDirect | |
Regionale Veloce 3973 · Regionale 17831 · Tuscany Line 18519 | 10:53 AM Venice Mestre | 3h59 | 2:52 PM Florence Santa Maria Novella | 2 transfers | |
8929 | 11:17 AM Venice Mestre | 2h03 | 1:20 PM Florence Santa Maria Novella | 0 transfersDirect | |
FRECCIAROSSA 1000 8419 | 11:38 AM Venice Mestre | 2h01 | 1:39 PM Florence Santa Maria Novella | 0 transfersDirect | |
Regionale Veloce 3975 · Regionale 17833 · Tuscany Line 18521 | 11:53 AM Venice Mestre | 3h59 | 3:52 PM Florence Santa Maria Novella | 2 transfers | |
Intercity 584+ Regionale Veloce 4042 | 12:05 PM Venice Mestre | 3h28 | 3:33 PM Florence Santa Maria Novella | 1 transfer | |
8913 | 12:17 PM Venice Mestre | 2h03 | 2:20 PM Florence Santa Maria Novella | 0 transfersDirect | |
FRECCIAROSSA 9421 | 12:38 PM Venice Mestre | 2h01 | 2:39 PM Florence Santa Maria Novella | 0 transfersDirect | |
Regionale Veloce 3977+ Intercity 597+ Regionale 18232 | 12:53 PM Venice Mestre | 3h59 | 4:52 PM Florence Santa Maria Novella | 2 transfers | |
Regionale Veloce 3977 · Regionale 17837 · Tuscany Line 18525 | 12:53 PM Venice Mestre | 3h59 | 4:52 PM Florence Santa Maria Novella | 2 transfers | |
8915 | On time 1:17 PM Venice Mestre | 2h03 | 3:20 PM Florence Santa Maria Novella | 0 transfersDirect | |
FRECCIAROSSA 9425 | 1:38 PM Venice Mestre | 2h01 | 3:39 PM Florence Santa Maria Novella | 0 transfersDirect | |
Regionale Veloce 3979 · Regionale 17839 · Tuscany Line 18527 | 1:53 PM Venice Mestre | 3h59 | 5:52 PM Florence Santa Maria Novella | 2 transfers | |
8919 | 2:17 PM Venice Mestre | 2h03 | 4:20 PM Florence Santa Maria Novella | 0 transfersDirect | |
Intercity 594+ Regionale 18312 | 2:34 PM Venice Mestre | 3h09 | 5:43 PM Florence Santa Maria Novella | 1 transfer | |
FRECCIAROSSA 1000 9427 | 2:38 PM Venice Mestre | 2h01 | 4:39 PM Florence Santa Maria Novella | 0 transfersDirect | |
Regionale Veloce 3981 · Regionale 17843 · TUSCANY LINE 18529 | 2:53 PM Venice Mestre | 3h59 | 6:52 PM Florence Santa Maria Novella | 2 transfers | |
8923 | On time 3:17 PM Venice Mestre | 2h03 | 5:20 PM Florence Santa Maria Novella | 0 transfersDirect | |
FRECCIAROSSA 1000 9431 | 3:38 PM Venice Mestre | 2h01 | 5:39 PM Florence Santa Maria Novella | 0 transfersDirect | |
Regionale Veloce 3983 · Regionale TTPER 17847 · TUSCANY LINE 18531 | 3:53 PM Venice Mestre | 3h59 | 7:52 PM Florence Santa Maria Novella | 2 transfers | |
8925 | 4:17 PM Venice Mestre | 2h03 | 6:20 PM Florence Santa Maria Novella | 0 transfersDirect | |
FRECCIAROSSA 1000 9433 | 4:38 PM Venice Mestre | 2h01 | 6:39 PM Florence Santa Maria Novella | 0 transfersDirect | |
Regionale Veloce 3985+ Intercity 599 | 4:53 PM Venice Mestre | 3h29 | 8:22 PM Florence Santa Maria Novella | 1 transfer | |
Regionale Veloce 3985 · Regionale 17851 | 4:53 PM Venice Mestre | 4h17 | 9:10 PM Florence Santa Maria Novella | 1 transfer | |
8927 | On time 5:17 PM Venice Mestre | 2h03 | 7:20 PM Florence Santa Maria Novella | 0 transfersDirect | |
FRECCIAROSSA 9435 | 5:38 PM Venice Mestre | 2h01 | 7:39 PM Florence Santa Maria Novella | 0 transfersDirect | |
FRECCIAROSSA 1000 9437 | 6:38 PM Venice Mestre | 2h01 | 8:39 PM Florence Santa Maria Novella | 0 transfersDirect | |
Regionale Veloce 3989 · Regionale 17853 · Tuscany Line 18539 | 6:53 PM Venice Mestre | 3h57 | 10:50 PM Florence Santa Maria Novella | 2 transfers | |
Find all the dates and times for this journey
Compare prices and tickets Venice Mestre to Florence Santa Maria Novella by bus or train
Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Venice Mestre to Florence Santa Maria Novella trains with Omio?
Italo as well as Frecciarossa, Regionale and Intercity offer trains services from Venice Mestre to Florence Santa Maria Novella. Omio is an official ticket reseller for all your travel options from Venice Mestre to Florence Santa Maria Novella.
Why book with Omio vs Italo?
- Compare with other providers: On Omio, you can not only buy tickets for Italo, but also compare tickets for the likes of Frecciarossa, Regionale and Intercity to find the best option for your trip from Venice Mestre to Florence Santa Maria Novella.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Italo with all available travel options, which are bus and train to ensure you get the best deal for traveling from Venice Mestre to Florence Santa Maria Novella.
Why book with Omio over Trainline and Rail Europe?
- Multiple travel company options: While Italo tickets can be bought on Italo's website or third party sellers, Omio allows you to compare with the likes of Frecciarossa, Regionale and Intercity to help you choose the right option for your journey from Venice Mestre to Florence Santa Maria Novella.
- Multiple modes of transport: Omio allows you to compare travel options including bus and train to find the ideal travel option from Venice Mestre to Florence Santa Maria Novella.
Journey information
Overview: Train from Venice Mestre to Florence Santa Maria Novella
Trains from Venice Mestre to Florence Santa Maria Novella run on average 24 times per day, taking around 3h 25m. Cheap train tickets for this journey start at $26 (€21) but you can travel from only $9 (€7) by bus.
There are 15 trains per day. The earliest train runs at 04:53, the last at 17:53. The fastest train covers the 127 miles (205 km) distance in 2h 0m.
Distance 127 miles (205 km) |
Average train duration 3h 25m |
Cheapest ticket price $26 (€21) |
Trains per day 24 |
Direct trains 15 |
Fastest train 2h 0m |
First train 04:53 |
Last train 17:53 |
Train companies: Italo, Frecciarossa, Regionale, Intercity, Intercity Notte from Venice Mestre to Florence Santa Maria Novella trainsItalo, Frecciarossa, Regionale, Intercity, Intercity Notte trains will get you between Venice Mestre and Florence Santa Maria Novella from $9 (€7). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Italo
Frecciarossa
Regionale
Intercity
Intercity Notte
FAQs: Trains from Venice Mestre to Florence Santa Maria Novella
Find answers to the most common questions about traveling from Venice Mestre to Florence Santa Maria Novella by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Florence Santa Maria Novella, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Venice Mestre to Florence Santa Maria Novella
- Mon - Sun: 05:50 - 20:30
- Provided by KiPoint and located on the ground floor.
- McDonald’s
- Chock Full O'Nuts
- Puro Gusto
- Juice Bar
- Rossosapore
- Full accessibility facilities, including toilets, ramps, wheelchairs, elevators and a mobility assistance center.
- Best Western Hotel Tritone
- The Plaza Hotel
- Hotel Villa Constanza
- Mon - Sun: 05:50 - 20:30
- Located in the main concourse.
- Bus lines: 2, 3, 10, 15, 18, 25a, 31, 31H, 32, 32H, 33H, 34H, 43, 53, 86, N1, 8AE
- Train lines: FR, FA, FB, EC, RJ, IC, EN, ICN, R, Italo
- Mon - Sun: 06:00 - 21:00
- Free WiFi (30 minutes limit).
- Provided by KiPoint and located on the ground floor, on the side of Piazza Adua. Open daily from 06:00 to 23:00.
- 12oz Coffee Joint
- Casa Maioli
- Don Nino
- Fratelli Cuore
- McDonald´s
- Panella
- Segafredo Zanetti
- Spizzico
- Venchi
- & many more
- Elevators, escalators, step-free access. Mobility assistance is available with the Sala Blu, located next to Platform 1.
- Hotel Luxor Florence
- Joy Hotel Florence
- Diplomat Hotel Florence
- Mon - Sun: 06:00 - 21:00
- Located inside and outside the station.
- Tram lines: T1, T2
- Bus lines: 6, 11, 12, 13, 17, 23, 36, 37, C4
- Train lines: FR, FA, Italo
Most popular train connections from Venice Mestre
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