The cheapest and fastest trains from Naples Centrale to Florence Santa Maria Novella
Cheapest price
$48
Average price
$90
Fastest journey
2 h 50 m
Average duration
2 h 55 m
Trains per day
69
Distance
409 km
The best way to find a cheap train ticket from Naples Centrale to Florence Santa Maria Novella is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Naples Centrale to Florence Santa Maria Novella will cost around $90 if you buy it on the day, but the cheapest tickets can be found for only $48.
Of the 69 trains that leave Naples Centrale for Florence Santa Maria Novella on Mon, Feb 23, 49 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Mon, Feb 23 the direct trains cover the 409 km distance in an average of 2 h 55 m but if you time it right, some trains will get you there in just 2 h 50 m .
On Mon, Feb 23 the slowest trains will take 2 h 56 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
Regionale 21096 · Regionale Veloce 4110
Regionale 21060 · Regionale Veloce 4152 · Regionale Veloce 4100
Regionale 21400 · Regionale Veloce 4154 · Regionale Veloce 4104
Regionale 21056 · Regionale Veloce 4098
Regionale 21080 · Regionale Veloce 4106
FRECCIAROSSA 1000 9674
8956
8922
8910
8918Travel Information
Compare train, bus, and flight for Naples Centrale to Florence Santa Maria Novella
Omio recommends booking the train as it is the most popular option from Naples Centrale to Florence Santa Maria Novella among Omio's users. If you are prioritising price take the bus with prices starting from €9. For those with little time consider booking a flight which can get you there in 1h 50m. The ticket price range depends on the travel mode: a bus costs an average of €9, and a flight costs an average of €142.
Distance: 254 miles (409 km)
Compare train with
Most popular Train | Bus | Flight |
|---|---|---|
€57 Average price | €20 Average price Cheapest | €236 Average price |
5h 32m Average total duration 5h 2m Onboard + 30m Additional time* | 6h 24m Average total duration 5h 54m Onboard + 30m Additional time* | 4h 50m Average total duration Fastest 1h 50m Onboard + 3h 0m Additional time* |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Live departures
Naples Centrale to Florence Santa Maria Novella train times
The table below shows live departures for Naples Centrale to Florence Santa Maria Novella trains for today, Sunday, February 22. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets | |
|---|---|---|---|---|---|---|
FRECCIAROSSA 1000 9406 | 5:09 AM Naples Centrale | 3h02 | 8:11 AM Florence Santa Maria Novella | 0 transfersDirect | ||
9912 | 5:14 AM Naples Centrale | 3h03 | 8:17 AM Florence Santa Maria Novella | 0 transfersDirect | ||
8904 | 5:19 AM Naples Centrale | 3h12 | 8:31 AM Florence Santa Maria Novella | 0 transfersDirect | ||
Regionale 21062+ UrbV Urb+ Regionale Veloce 4100 | 5:37 AM Naples Centrale | 8h11 | 1:48 PM Florence Santa Maria Novella | 2 transfers | ||
FRECCIAROSSA 9516 | 5:40 AM Naples Centrale | 3h06 | 8:46 AM Florence Santa Maria Novella | 0 transfersDirect | ||
8956 | On time 6:02 AM Naples Centrale | 2h55 | 8:57 AM Florence Santa Maria Novella | 0 transfersDirect | ||
FRECCIAROSSA 9490 | 6:09 AM Naples Centrale | 3h02 | 9:11 AM Florence Santa Maria Novella | 0 transfersDirect | ||
9916 | On time 6:20 AM Naples Centrale | 2h57 | 9:17 AM Florence Santa Maria Novella | 0 transfersDirect | ||
FRECCIAROSSA 8506 | 6:30 AM Naples Centrale | 2h57 | 9:27 AM Florence Santa Maria Novella | 0 transfersDirect | ||
Intercity 510 · Intercity 588+ Regionale 18222 | 6:31 AM Naples Centrale | 6h21 | 12:52 PM Florence Santa Maria Novella | 2 transfers | ||
Intercity 510+ Regionale Veloce 4034 | 6:31 AM Naples Centrale | 6h30 | 1:01 PM Florence Santa Maria Novella | 1 transfer | ||
FRECCIAROSSA 9520 | 6:45 AM Naples Centrale | 3h01 | 9:46 AM Florence Santa Maria Novella | 0 transfersDirect | ||
FRECCIAROSSA 9414 | 7:09 AM Naples Centrale | 3h02 | 10:11 AM Florence Santa Maria Novella | 0 transfersDirect | ||
9920 | 7:20 AM Naples Centrale | 2h57 | 10:17 AM Florence Santa Maria Novella | 0 transfersDirect | ||
8908 | 7:30 AM Naples Centrale | 3h01 | 10:31 AM Florence Santa Maria Novella | 0 transfersDirect | ||
Regionale 21068 · ETRUSCHI LINE 34476 · Tuscany Line 4044 | 7:30 AM Naples Centrale | 9h03 | 4:33 PM Florence Santa Maria Novella | 2 transfers | ||
FRECCIAROSSA 9524 | 7:40 AM Naples Centrale | 3h06 | 10:46 AM Florence Santa Maria Novella | 0 transfersDirect | ||
FRECCIAROSSA 9310 | 7:55 AM Naples Centrale | 3h06 | 11:01 AM Florence Santa Maria Novella | 0 transfersDirect | ||
Intercity 590+ Regionale 18415 | 8:15 AM Naples Centrale | 7h53 | 4:08 PM Florence Santa Maria Novella | 1 transfer | ||
9924 | 8:20 AM Naples Centrale | 2h57 | 11:17 AM Florence Santa Maria Novella | 0 transfersDirect | ||
8910 | On time 8:35 AM Naples Centrale | 2h56 | 11:31 AM Florence Santa Maria Novella | 0 transfersDirect | ||
FRECCIAROSSA 9532 | 9:40 AM Naples Centrale | 3h06 | 12:46 PM Florence Santa Maria Novella | 0 transfersDirect | ||
FRECCIAROSSA 1000 9420 | 10:10 AM Naples Centrale | 3h01 | 1:11 PM Florence Santa Maria Novella | 0 transfersDirect | ||
9932 | 10:20 AM Naples Centrale | 2h57 | 1:17 PM Florence Santa Maria Novella | 0 transfersDirect | ||
Intercity 550+ Regionale Veloce 4730 · Regionale Veloce 4104 | 10:31 AM Naples Centrale | 7h17 | 5:48 PM Florence Santa Maria Novella | 2 transfers | ||
FRECCIAROSSA 9584 | 10:40 AM Naples Centrale | 3h06 | 1:46 PM Florence Santa Maria Novella | 0 transfersDirect | ||
FRECCIAROSSA 9422 | 11:10 AM Naples Centrale | 3h01 | 2:11 PM Florence Santa Maria Novella | 0 transfersDirect | ||
8134 | 11:15 AM Naples Centrale | 3h02 | 2:17 PM Florence Santa Maria Novella | 0 transfersDirect | ||
Intercity 700 · Intercity 592+ Regionale 18401 | 11:36 AM Naples Centrale | 6h32 | 6:08 PM Florence Santa Maria Novella | 2 transfers | ||
FRECCIAROSSA 9540 | 11:40 AM Naples Centrale | 3h06 | 2:46 PM Florence Santa Maria Novella | 0 transfersDirect | ||
FRECCIAROSSA 1000 9640 · FRECCIAROSSA 1000 9423 | 11:55 AM Naples Centrale | 3h16 | 3:11 PM Florence Santa Maria Novella | 1 transfer | ||
Intercity 596+ Tuscany Line 4052 | 12:01 PM Naples Centrale | 6h32 | 6:33 PM Florence Santa Maria Novella | 1 transfer | ||
9940 | 12:20 PM Naples Centrale | 2h57 | 3:17 PM Florence Santa Maria Novella | 0 transfersDirect | ||
Intercity 552 · Intercity 518+ TUSCANY LINE 18316 | 12:26 PM Naples Centrale | 6h35 | 7:01 PM Florence Santa Maria Novella | 2 transfers | ||
8918 | On time 12:35 PM Naples Centrale | 2h56 | 3:31 PM Florence Santa Maria Novella | 0 transfersDirect | ||
FRECCIAROSSA 9544 | 12:40 PM Naples Centrale | 3h06 | 3:46 PM Florence Santa Maria Novella | 0 transfersDirect | ||
Regionale 21084 · Regionale Veloce 4106 | 12:45 PM Naples Centrale | 7h10 | 7:55 PM Florence Santa Maria Novella | 1 transfer | ||
FRECCIAROSSA 9320 | 12:55 PM Naples Centrale | 3h06 | 4:01 PM Florence Santa Maria Novella | 0 transfersDirect | ||
FRECCIAROSSA 9426 | 1:10 PM Naples Centrale | 3h01 | 4:11 PM Florence Santa Maria Novella | 0 transfersDirect | ||
9946 | 1:20 PM Naples Centrale | 2h57 | 4:17 PM Florence Santa Maria Novella | 0 transfersDirect | ||
Intercity 1588+ TUSCANY LINE 4058 | 1:30 PM Naples Centrale | 6h03 | 7:33 PM Florence Santa Maria Novella | 1 transfer | ||
FRECCIAROSSA 9428 | 2:10 PM Naples Centrale | 3h01 | 5:11 PM Florence Santa Maria Novella | 0 transfersDirect | ||
9948 | On time 2:20 PM Naples Centrale | 2h57 | 5:17 PM Florence Santa Maria Novella | 0 transfersDirect | ||
Intercity 556 · Intercity 598 | 2:31 PM Naples Centrale | 6h29 | 9:00 PM Florence Santa Maria Novella | 1 transfer | ||
8920 | 2:35 PM Naples Centrale | 2h56 | 5:31 PM Florence Santa Maria Novella | 0 transfersDirect | ||
FRECCIAROSSA 9552 | 2:40 PM Naples Centrale | 3h06 | 5:46 PM Florence Santa Maria Novella | 0 transfersDirect | ||
FRECCIAROSSA 1000 9430 | 3:09 PM Naples Centrale | 3h02 | 6:11 PM Florence Santa Maria Novella | 0 transfersDirect | ||
Regionale 21094 · Regionale Veloce 4110 | 3:17 PM Naples Centrale | 7h33 | 10:50 PM Florence Santa Maria Novella | 1 transfer | ||
Intercity 734+ Regionale Veloce 4110 | 3:31 PM Naples Centrale | 7h19 | 10:50 PM Florence Santa Maria Novella | 1 transfer | ||
8922 | 3:35 PM Naples Centrale | 2h56 | 6:31 PM Florence Santa Maria Novella | 0 transfersDirect | ||
FRECCIAROSSA 1000 9556 | 3:40 PM Naples Centrale | 3h06 | 6:46 PM Florence Santa Maria Novella | 0 transfersDirect | ||
FRECCIAROSSA 9660 · FRECCIAROSSA 1000 9326 | 3:55 PM Naples Centrale | 3h06 | 7:01 PM Florence Santa Maria Novella | 1 transfer | ||
FRECCIAROSSA 9432 | 4:05 PM Naples Centrale | 3h27 | 7:32 PM Florence Santa Maria Novella | 0 transfersDirect | ||
9954 | 4:20 PM Naples Centrale | 2h57 | 7:17 PM Florence Santa Maria Novella | 0 transfersDirect | ||
FRECCIAROSSA 1000 9662 · FRECCIAROSSA 1000 8528 | 4:25 PM Naples Centrale | 3h02 | 7:27 PM Florence Santa Maria Novella | 1 transfer | ||
8968 | On time 4:55 PM Naples Centrale | 3h02 | 7:57 PM Florence Santa Maria Novella | 0 transfersDirect | ||
FRECCIAROSSA 1000 9434 | 5:10 PM Naples Centrale | 3h01 | 8:11 PM Florence Santa Maria Novella | 0 transfersDirect | ||
8158 | 5:20 PM Naples Centrale | 2h57 | 8:17 PM Florence Santa Maria Novella | 0 transfersDirect | ||
FRECCIAROSSA 9592 | 5:40 PM Naples Centrale | 3h06 | 8:46 PM Florence Santa Maria Novella | 0 transfersDirect | ||
9962 | 6:20 PM Naples Centrale | 2h57 | 9:17 PM Florence Santa Maria Novella | 0 transfersDirect | ||
FRECCIAROSSA 1000 9568 | 6:40 PM Naples Centrale | 3h18 | 9:58 PM Florence Santa Maria Novella | 0 transfersDirect | ||
FRECCIAROSSA 1000 9674 | 7:30 PM Naples Centrale | 2h50 | 10:20 PM Florence Santa Maria Novella | 0 transfersDirect | ||
FRECCIAROSSA 1000 9555+ InterCityNotte 1962+ Regionale 18730 | 9:30 PM Naples Centrale | 7h30 | 5:00 AM Florence Santa Maria Novella | 2 transfers | ||
| Monday, February 23 | ||||||
Regionale 21052 · Regionale Veloce 4712 · Regionale Veloce 4096 | 3:05 AM Naples Centrale | 6h43 | 9:48 AM Florence Santa Maria Novella | 2 transfers | ||
FRECCIAROSSA 1000 9606 · FRECCIAROSSA 1000 9404 | 4:09 AM Naples Centrale | 3h02 | 7:11 AM Florence Santa Maria Novella | 1 transfer | ||
Regionale 21056 · Regionale Veloce 4098 | 4:09 AM Naples Centrale | 7h41 | 11:50 AM Florence Santa Maria Novella | 1 transfer | ||
9908 | 4:14 AM Naples Centrale | 3h03 | 7:17 AM Florence Santa Maria Novella | 0 transfersDirect | ||
FRECCIAROSSA 9304 | 4:23 AM Naples Centrale | 3h38 | 8:01 AM Florence Santa Maria Novella | 0 transfersDirect | ||
FRECCIAROSSA 1000 8334 · FRECCIAROSSA 9304 | 4:45 AM Naples Centrale | 3h16 | 8:01 AM Florence Santa Maria Novella | 1 transfer | ||
8954 | 4:50 AM Naples Centrale | 3h07 | 7:57 AM Florence Santa Maria Novella | 0 transfersDirect | ||
Find all the dates and times for this journey
Compare prices and tickets Naples Centrale to Florence Santa Maria Novella by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Naples Centrale to Florence Santa Maria Novella trains with Omio?
Why book with Omio vs Italo?
- Compare with other providers: On Omio, you can not only buy tickets for Italo, but also compare tickets for the likes of Frecciarossa, Regionale, Intercity or Intercity Notte to find the best option for your trip from Naples Centrale to Florence Santa Maria Novella.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Italo with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Naples Centrale to Florence Santa Maria Novella.
Journey information
Overview: Train from Naples Centrale to Florence Santa Maria Novella
Trains from Naples Centrale to Florence Santa Maria Novella run on average 42 times per day, taking around 5h 2m. Cheap train tickets for this journey start at $32 (€26) but you can travel from only $12 (€9) by bus.
There are 30 trains per day. The earliest train runs at 04:00, the last at 20:43. The fastest train covers the 254 miles (409 km) distance in 2h 50m.
Distance 254 miles (409 km) |
Average train duration 5h 2m |
Cheapest ticket price $32 (€26) |
Trains per day 42 |
Direct trains 30 |
Fastest train 2h 50m |
First train 04:00 |
Last train 20:43 |
Train companies: Italo, Frecciarossa, Regionale, Intercity, Intercity Notte from Naples Centrale to Florence Santa Maria Novella trainsItalo, Frecciarossa, Regionale, Intercity, Intercity Notte trains will get you between Naples Centrale and Florence Santa Maria Novella from $12 (€9). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Italo
Frecciarossa
Regionale
Intercity
Intercity Notte
FAQs: Trains from Naples Centrale to Florence Santa Maria Novella
Find answers to the most common questions about traveling from Naples Centrale to Florence Santa Maria Novella by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Florence Santa Maria Novella, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Naples Centrale to Florence Santa Maria Novella
- Mon - Sun: 05:50 - 21:10
- Free WiFi throughout the station.
- KiPoint luggage storage is located close to Platform 2, open daily from 06:00 to 23:00.
- Tentazioni Cafe
- Burger King
- VyTA Boulangerie
- Time Cafè
- Caffè Toraldo
- Chalet Ciro
- Cibiamo
- Chef Express
- Eccellenze Della Costiera
- 100 Montaditos
- & more
- The station is fully accessible. The Sala Blu office provides services and assists customers with disabilities.
- Grand Hotel Europa
- Starhotels Terminus
- B&B Hotel Napoli
- Mon - Sun: 05:50 - 21:10
- Located on the ground floor in the main concourse.
- Metro lines: 1, 2
- Tram lines: 1, 2
- Bus lines: 116, 130, 150, 151, 175, 191, 195, 196, 202 (Filobus), 254 (Filobus), 254 (Filobus), 455, 460, 469, 472, 475, 606, Alibus, N1, N3, N4, N5, N8, R2, R5
- Train lines: FR, FA, FB, IC, ICN, R, Circumvesuviana (3, 12, 14, 15), Italo
- Mon - Sun: 06:00 - 21:00
- Free WiFi (30 minutes limit).
- Provided by KiPoint and located on the ground floor, on the side of Piazza Adua. Open daily from 06:00 to 23:00.
- 12oz Coffee Joint
- Casa Maioli
- Don Nino
- Fratelli Cuore
- McDonald´s
- Panella
- Segafredo Zanetti
- Spizzico
- Venchi
- & many more
- Elevators, escalators, step-free access. Mobility assistance is available with the Sala Blu, located next to Platform 1.
- Hotel Luxor Florence
- Joy Hotel Florence
- Diplomat Hotel Florence
- Mon - Sun: 06:00 - 21:00
- Located inside and outside the station.
- Tram lines: T1, T2
- Bus lines: 6, 11, 12, 13, 17, 23, 36, 37, C4
- Train lines: FR, FA, Italo
More options for your journey from Naples Centrale to Florence Santa Maria Novella
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