Travel Information
Compare bus, train, and flight for Philadelphia, PA to South San Francisco, CA
Omio recommends booking the bus as it is the most popular option from Philadelphia, PA to South San Francisco, CA among Omio's users. If you are prioritising price take the flight with prices starting from €212. For those with little time consider booking a flight which can get you there in 10h 13m. The ticket price range depends on the travel mode: a flight costs an average of €212, and a train costs an average of €367.
Distance: 2519 miles (4054 km)
Compare train with
| Train | Most popular Bus | Flight |
|---|---|---|
€458 Average price | €292 Average price | €290 Average price Cheapest |
87h 14m Average total duration 86h 44m Onboard + 30m Additional time* | 67h 5m Average total duration 66h 35m Onboard + 30m Additional time* | 13h 13m Average total duration Fastest 10h 13m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
Compare prices and tickets Philadelphia, PA to South San Francisco, CA by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Train from Philadelphia, PA to South San Francisco, CA
Trains from Philadelphia, PA to South San Francisco, CA run on average 9 times per day, taking around 86h 44m. Cheap train tickets for this journey start at $451 (€367) but you can travel from only $236 (€192) by bus.
The earliest train runs at 12:15, the last at 19:55. The fastest train covers the 2519 miles (4054 km) distance in 79h 15m.
Distance 2519 miles (4054 km) |
Average train duration 86h 44m |
Cheapest ticket price $451 (€367) |
Trains per day 9 |
Fastest train 79h 15m |
First train 12:15 |
Last train 19:55 |
FAQs: Trains from Philadelphia, PA to South San Francisco, CA
Find answers to the most common questions about traveling from Philadelphia, PA to South San Francisco, CA by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at South San Francisco, CA, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Philadelphia, PA to South San Francisco, CA
- 5:15 AM - 10:30 PM Monday - Sunday
- Free
- The car park is open 24/7. Access via 30th Street and Market Street.
- Bridgewater's Pub
- The Porch at 30th Street Station
- Outside the main entrance.
- Elevators, ramps, restrooms.
- $1
- The Inn at Penn, a Hilton Hotel
- Sheraton Philadelphia University City Hotel
- The Study at University City
- Located in the main hall
- Located in the main hall
- Enterprise
- Hertz
- Located in the main hall
- Free
- Main Hall: entrance, ticketing, and waiting area
- Upper Level: Amtrak platforms
- Lower Level: SEPTA Regional Rail platforms
- SEPTA: Market-Frankford Line
- Trolley: Routes 10, 11, 13, 34, 36
- Bus: Several lines available
Most popular train connections from Philadelphia, PA
More options for your journey from Philadelphia, PA to South San Francisco, CA
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