The cheapest and fastest trains from Philadelphia, PA to South San Francisco, CA
Cheapest price
$405
Average price
$405
Fastest journey
3 d 7 h 22 m
Average duration
3 d 7 h 22 m
Trains per day
1
Distance
4054 km
The best way to find a cheap train ticket from Philadelphia, PA to South San Francisco, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Philadelphia, PA to South San Francisco, CA will cost around $405 if you buy it on the day, but the cheapest tickets can be found for only $405.
Of the 1 trains that leave Philadelphia, PA for South San Francisco, CA on Tue, Feb 17, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Tue, Feb 17 the direct trains cover the 4054 km distance in an average of 3 d 7 h 22 m but if you time it right, some trains will get you there in just 3 d 7 h 22 m .
On Tue, Feb 17 the slowest trains will take 3 d 7 h 22 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Travel Information
Compare bus, train, and flight for Philadelphia, PA to South San Francisco, CA
Omio recommends booking the bus as it is the most popular option from Philadelphia, PA to South San Francisco, CA among Omio's users. If you are prioritising price take the flight with prices starting from €193. For those with little time consider booking a flight which can get you there in 10h 26m. The ticket price range depends on the travel mode: a flight costs an average of €193, and a train costs an average of €367.
Distance: 2519 miles (4054 km)
Compare train with
| Train | Most popular Bus | Flight |
|---|---|---|
€550 Average price | €469 Average price | €222 Average price Cheapest |
79h 58m Average total duration 79h 28m Onboard + 30m Additional time* | 67h 5m Average total duration 66h 35m Onboard + 30m Additional time* | 13h 26m Average total duration Fastest 10h 26m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
Compare prices and tickets Philadelphia, PA to South San Francisco, CA by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Feb 17
Feb 18
Feb 19
Feb 20
Feb 21
Feb 22
Feb 23
Journey information
Overview: Train from Philadelphia, PA to South San Francisco, CA
Trains from Philadelphia, PA to South San Francisco, CA run on average 7 times per day, taking around 79h 28m. Cheap train tickets for this journey start at $464 (€367) but you can travel from only $243 (€193) by flight.
The earliest train runs at 17:00, the last at 17:42. The fastest train covers the 2519 miles (4054 km) distance in 79h 16m.
Distance 2519 miles (4054 km) |
Average train duration 79h 28m |
Cheapest ticket price $464 (€367) |
Trains per day 7 |
Fastest train 79h 16m |
First train 17:00 |
Last train 17:42 |
FAQs: Trains from Philadelphia, PA to South San Francisco, CA
Find answers to the most common questions about traveling from Philadelphia, PA to South San Francisco, CA by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at South San Francisco, CA, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Philadelphia, PA to South San Francisco, CA
- 5:15 AM - 10:30 PM Monday - Sunday
- Free
- The car park is open 24/7. Access via 30th Street and Market Street.
- Bridgewater's Pub
- The Porch at 30th Street Station
- Outside the main entrance.
- Elevators, ramps, restrooms.
- $1
- The Inn at Penn, a Hilton Hotel
- Sheraton Philadelphia University City Hotel
- The Study at University City
- Located in the main hall
- Located in the main hall
- Enterprise
- Hertz
- Located in the main hall
- Free
- Main Hall: entrance, ticketing, and waiting area
- Upper Level: Amtrak platforms
- Lower Level: SEPTA Regional Rail platforms
- SEPTA: Market-Frankford Line
- Trolley: Routes 10, 11, 13, 34, 36
- Bus: Several lines available
Most popular train connections from Philadelphia, PA
More options for your journey from Philadelphia, PA to South San Francisco, CA
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