Travel Information
Compare bus, train, and flight for San Diego, CA to South San Francisco, CA
Omio recommends booking the flight as it is the most popular option from San Diego, CA to South San Francisco, CA among Omio's users. If you are prioritising price take the bus with prices starting from €59. For those with little time consider booking a flight which can get you there in 2h 38m. The ticket price range depends on the travel mode: a bus costs an average of €59, and a flight costs an average of €94.
Distance: 451 miles (727 km)
Compare train with
| Train | Most popular Flight | Bus |
|---|---|---|
€68 Average price | €180 Average price | €59 Average price Cheapest |
14h 29m Average total duration 13h 59m Onboard + 30m Additional time* | 5h 38m Average total duration Fastest 2h 38m Onboard + 3h 0m Additional time* | 14h 11m Average total duration 13h 41m Onboard + 30m Additional time* |
Direct Options | Direct Options | Direct Options |
Live departures
San Diego, CA to South San Francisco, CA train times
The table below shows live departures for San Diego, CA to South San Francisco, CA trains for today, Monday, February 16. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
765 Pacific Surfliner · 14 Coast Starlight · 6619 AMTRAK | 2:01 PM Santa Fe Depot, San Diego, CA | 16h29 | 6:30 AM South San Francisco, CA | 2 transfers | |
769 Pacific Surfliner · 5719 AMTRAK · 719 Gold Runner · 6619 AMTRAK | 4:01 PM Santa Fe Depot, San Diego, CA | 14h29 | 6:30 AM South San Francisco, CA | 3 transfers | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets San Diego, CA to South San Francisco, CA by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Feb 17
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Feb 22
Feb 23
Journey information
Overview: Train from San Diego, CA to South San Francisco, CA
Trains from San Diego, CA to South San Francisco, CA run on average 17 times per day, taking around 13h 59m. Cheap train tickets for this journey start at $86 (€68) but you can travel from only $74 (€59) by bus.
The earliest train runs at 04:01, the last at 22:35. The fastest train covers the 451 miles (727 km) distance in 13h 59m.
Distance 451 miles (727 km) |
Average train duration 13h 59m |
Cheapest ticket price $86 (€68) |
Trains per day 17 |
Fastest train 13h 59m |
First train 04:01 |
Last train 22:35 |
FAQs: Trains from San Diego, CA to South San Francisco, CA
Find answers to the most common questions about traveling from San Diego, CA to South San Francisco, CA by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at South San Francisco, CA, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from San Diego, CA to South San Francisco, CA
- 5:00 AM - 10:00 PM Monday - Sunday
- Free
- Parking is available nearby with various public and private options.
- The Fish Market
- Karl Strauss Brewing Company
- Outside the main entrance.
- Ramps.
- $1.25
- The Westin San Diego
- The Guild Hotel, San Diego, a Tribute Portfolio Hotel
- Embassy Suites by Hilton San Diego Bay Downtown
- Located in the main hall
- Enterprise
- Hertz
- Located in the main hall
- Free
- Hall 1: main entrance, platforms for Amtrak and Coaster trains
- Hall 2: Trolley connections
- San Diego Trolley: Blue Line, Green Line
- Bus: Several lines available
- Amtrak: Pacific Surfliner
- 6:00 AM - 9:00 PM Monday - Sunday
- Free
- Parking is available with several spaces for commuters and visitors.
- Casa Guadalajara
- Old Town Mexican Cafe
- Outside the main entrance.
- Elevators, ramps.
- $0.25
- Old Town Inn
- Fairfield Inn & Suites by Marriott San Diego Old Town
- Best Western Plus Hacienda Hotel Old Town
- Located in the main hall
- Enterprise
- Hertz
- Located in the main hall
- Free
- Hall 1: main entrance, platforms for Amtrak and Coaster trains
- Hall 2: Trolley connections
- Trolley: Green Line
- Bus: Several lines available including 8, 9, 10, 28, 30, 35, 44, 88, 105, 150, 923, 928
Most popular train connections from San Diego, CA
More options for your journey from San Diego, CA to South San Francisco, CA
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