Travel Information
Compare bus, train, and flight for Indianapolis, IN to South San Francisco, CA
Omio recommends booking the flight as it is the most popular option from Indianapolis, IN to South San Francisco, CA among Omio's users. If you are prioritising price take the bus with prices starting from €262. For those with little time consider booking a flight which can get you there in 12h 19m. The ticket price range depends on the travel mode: a bus costs an average of €262, and a flight costs an average of €386.
Distance: 1946 miles (3133 km)
Compare train with
| Train | Most popular Flight | Bus |
|---|---|---|
€295 Average price | €386 Average price | €262 Average price Cheapest |
61h 17m Average total duration 60h 47m Onboard + 30m Additional time* | 15h 19m Average total duration Fastest 12h 19m Onboard + 3h 0m Additional time* | 65h 25m Average total duration 64h 55m Onboard + 30m Additional time* |
Direct Options | Direct Options | Direct Options |
Compare prices and tickets Indianapolis, IN to South San Francisco, CA by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Train from Indianapolis, IN to South San Francisco, CA
Trains from Indianapolis, IN to South San Francisco, CA run on average 2 times per day, taking around 60h 47m. Cheap train tickets for this journey start at $364 (€295) but you can travel from only $323 (€262) by bus.
The earliest train runs at 11:10, the last at 11:10. The fastest train covers the 1946 miles (3133 km) distance in 60h 47m.
Distance 1946 miles (3133 km) |
Average train duration 60h 47m |
Cheapest ticket price $364 (€295) |
Trains per day 2 |
Fastest train 60h 47m |
First train 11:10 |
Last train 11:10 |
FAQs: Trains from Indianapolis, IN to South San Francisco, CA
Find answers to the most common questions about traveling from Indianapolis, IN to South San Francisco, CA by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at South San Francisco, CA, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Indianapolis, IN to South San Francisco, CA
- 6:00 AM - 11:00 PM Monday - Sunday
- Free
- Parking is available a few blocks away from the station.
- Harry & Izzy's
- St. Elmo Steak House
- Outside the main entrance.
- Ramps.
- Free for passengers
- Crowne Plaza Indianapolis-Dwtn-Union-Stn
- Omni Severin Hotel
- The Westin Indianapolis
- Located in the main hall
- Free
- Hall 1: main entrance, platform for Amtrak's Cardinal line
- Bus: IndyGo routes available nearby
Most popular train connections from Indianapolis, IN
More options for your journey from Indianapolis, IN to South San Francisco, CA
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