Journey information
Overview: Panama City to Madrid flight
Flights from Panama City to Madrid depart on average 25 times per day, taking around 12h 0m. Cheap flight tickets for this journey start at $551 (€440) if you book in advance.
There are 1 flights per day. The earliest flight runs at 12:55, the last at 23:50. The fastest flight covers the 5061 miles (8145 km) distance in 10h 5m. November is the cheapest month to fly.
Distance 5061 miles (8145 km) |
Average flight duration 12h 0m |
Cheapest ticket price $551 (€440) |
Flights per day 25 |
Direct flights 1 |
Fastest flight 10h 5m |
Cheapest month to travel November |
First flight 12:55 |
Last flight 23:50 |
Live departures
Panama City to Madrid flight times
The table below shows live departures for Panama City to Madrid flights for today, Wednesday, December 17. You can also manually refresh the results below to see updated flight journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
AV41 · AV46 | 7:55 AM Panama City | 14h25 | 10:20 PM Madrid Barajas Airport | 1 transfer | |
AV41 · AV26 | 7:55 AM Panama City | 19h40 | 3:35 AM Madrid Barajas Airport | 1 transfer | |
IB7747+ IB244 | 12:55 PM Panama City | 21h45 | 10:40 AM Madrid Barajas Airport | 1 transfer | |
KL3050+ KL6277 · KL6028 | 2:14 PM Panama City | 18h01 | 8:15 AM Madrid Barajas Airport | 2 transfers | |
IB7731+ IB244 | 2:34 PM Panama City | 20h06 | 10:40 AM Madrid Barajas Airport | 1 transfer | |
AV59 · AV182 | 2:45 PM Panama City | 17h05 | 7:50 AM Madrid Barajas Airport | 1 transfer | |
AV59 · AV10 | 2:45 PM Panama City | 21h40 | 12:25 PM Madrid Barajas Airport | 1 transfer | |
AV59 · AV26 | 2:45 PM Panama City | 12h50 | 3:35 AM Madrid Barajas Airport | 1 transfer | |
UA727 · UA51 | 3:00 PM Panama City | 17h15 | 8:15 AM Madrid Barajas Airport | 1 transfer | |
IB4369+ IB338 | 7:50 PM Panama City | 16h15 | 12:05 PM Madrid Barajas Airport | 1 transfer | |
AV61 · AV9308 · AV16 | 7:55 PM Panama City | 16h55 | 12:50 PM Madrid Barajas Airport | 2 transfers | |
AV61 · AV10 | 7:55 PM Panama City | 16h30 | 12:25 PM Madrid Barajas Airport | 1 transfer | |
AV61 · AV9260 · AV16 | 7:55 PM Panama City | 16h55 | 12:50 PM Madrid Barajas Airport | 2 transfers | |
AV61 · AV9250 · AV16 | 7:55 PM Panama City | 16h55 | 12:50 PM Madrid Barajas Airport | 2 transfers | |
AV61 · AV9332 · AV16 | 7:55 PM Panama City | 16h55 | 12:50 PM Madrid Barajas Airport | 2 transfers | |
AV61 · AV9312 · AV16 | 7:55 PM Panama City | 16h55 | 12:50 PM Madrid Barajas Airport | 2 transfers | |
AV61 · AV9358 · AV16 | 7:55 PM Panama City | 16h55 | 12:50 PM Madrid Barajas Airport | 2 transfers | |
IB4826+ IB338 | 9:43 PM Panama City | 14h22 | 12:05 PM Madrid Barajas Airport | 1 transfer | |
AV57 · AV10 | 10:50 PM Panama City | 13h35 | 12:25 PM Madrid Barajas Airport | 1 transfer | |
IB258 | 11:20 PM Panama City | 10h05 | 9:25 AM Madrid Barajas Airport | 0 transfersDirect | |
KL3026+ KL760 · KL1507 | 11:40 PM Panama City | 19h00 | 6:40 PM Madrid Barajas Airport | 2 transfers | |
AF4370+ AF481 · AF1100 | 11:40 PM Panama City | 18h30 | 6:10 PM Madrid Barajas Airport | 2 transfers | |
AF4370+ AF481 · AF1800 | 11:40 PM Panama City | 17h00 | 4:40 PM Madrid Barajas Airport | 2 transfers | |
AF8226+ AF1641 · AF1100 | 11:45 PM Panama City | 18h25 | 6:10 PM Madrid Barajas Airport | 2 transfers | |
KL758 · KL1501 | 11:45 PM Panama City | 33h30 | 9:15 AM Madrid Barajas Airport | 1 transfer | |
KL758 · KL1509 | 11:45 PM Panama City | 22h40 | 10:25 PM Madrid Barajas Airport | 1 transfer | |
AF8226+ AF1501 · AF1800 | 11:45 PM Panama City | 16h55 | 4:40 PM Madrid Barajas Airport | 2 transfers | |
AF8226+ AF1741 · AF1100 | 11:45 PM Panama City | 18h25 | 6:10 PM Madrid Barajas Airport | 2 transfers | |
KL758 · KL1503 | 11:45 PM Panama City | 35h25 | 11:10 AM Madrid Barajas Airport | 1 transfer | |
KL758 · KL1505 | 11:45 PM Panama City | 15h20 | 3:05 PM Madrid Barajas Airport | 1 transfer | |
KL758 · KL1507 | 11:45 PM Panama City | 18h55 | 6:40 PM Madrid Barajas Airport | 1 transfer | |
AF8226+ AF1501 · AF1100 | 11:45 PM Panama City | 18h25 | 6:10 PM Madrid Barajas Airport | 2 transfers | |
KL758+ KL3393 | 11:45 PM Panama City | 36h55 | 12:40 PM Madrid Barajas Airport | 1 transfer | |
| Thursday, December 18 | |||||
AV316 · AV365 · AV46 | 12:50 AM Panama City | 21h30 | 10:20 PM Madrid Barajas Airport | 2 transfers | |
UX56 | 2:30 AM Panama City | 9h35 | 12:05 PM Madrid Barajas Airport | 0 transfersDirect | |
AF475 · AF1000 | 3:20 AM Panama City | 28h50 | 8:10 AM Madrid Barajas Airport | 1 transfer | |
AF475 · AF1400 | 3:20 AM Panama City | 18h45 | 10:05 PM Madrid Barajas Airport | 1 transfer | |
AF475 · AF1100 | 3:20 AM Panama City | 14h50 | 6:10 PM Madrid Barajas Airport | 1 transfer | |
AF475 · AF1600 | 3:20 AM Panama City | 35h00 | 2:20 PM Madrid Barajas Airport | 1 transfer | |
AF475 · AF1300 | 3:20 AM Panama City | 31h10 | 10:30 AM Madrid Barajas Airport | 1 transfer | |
AF475 · AF1800 | 3:20 AM Panama City | 13h20 | 4:40 PM Madrid Barajas Airport | 1 transfer | |
This is the last flight of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Panama City to Madrid by flight
Compare flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Airlines: Iberia, Air Europa, Air France, DELTA, KLM from Panama City to MadridFind the best flights between Panama City to Madrid with Omio's travel partners Iberia, Air Europa, Air France, DELTA, KLM from $551 (€440). We can find you the best deals, schedules and tickets when comparing and booking the best trip.
Air France
Iberia
Air Europa
DELTA
KLM
FAQs: Panama City to Madrid Flight
Find answers to the most common questions about traveling from Panama City to Madrid by flight. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest flight, the cheapest option, or tips for making the most of your visit at Madrid, this guide helps you travel smarter and with confidence.

- San Isidro Festival, a celebration honoring the patron saint of Madrid with parades and traditional music
- Madrid Pride, one of the largest LGBTQ+ pride events in Europe featuring a colorful parade
- La Paloma Festival, a local festival celebrating the Virgin of La Paloma with street parties and cultural activities
- Madrid Fashion Week, a showcase of the latest trends and designs from Spanish and international fashion designers.
- Epiphany, January, a traditional celebration with parades and the Three Kings' Day festivities
- Semana Santa, April, a significant religious observance with processions and cultural significance
- Assumption of Mary, August, a public holiday with various local celebrations and events
- National Day of Spain, October, commemorating the country's history with patriotic displays and activities.
Typically, passengers are allowed one carry-on bag and one personal item (for example a purse, laptop bag, or backpack). Personal items must fit under the seat in front of you.
Budget Airlines (like Ryanair or Wizz Air) have stricter size and weight limits, often requiring fees for larger carry-ons. Full-Service Airlines have more lenient policies, sometimes including more spacious dimensions or higher weight limits depending on your ticket class.
popular airports
Popular airports from Panama City to Madrid
- Free Wi-Fi available throughout the airport.
- Shops located in duty-free area, including local crafts and intertiol brands.
- Parking available, short-term and long-term, approximately 0.95€ ($1) per hour.
- Various restaurants in food court, including local cuisine and fast food
- Available outside the terminal.
- Elevators, ramps
- Available throughout the airport.
- Hotels nearby, such as Crowne Plaza Pama Airport.
- Showers available in some lounges, access may require lounge entry fee.
- Several lounges available, including Copa Club.
- Lost and Found located in the main terminal.
- Car rental services available from major providers like Hertz and Avis
- Metro Line 2, Estación Corredor Sur, 24 km
- Free Wi-Fi available throughout the airport.
- Shops in all terminals, including duty-free and fashion brands.
- Parking available at all terminals, approximately 2.5€ per hour.
- Available outside the terminal.
- Ramps, assistance.
- Available throughout the airport.
- Yes
- Lounges available in all terminals, including VIP lounges.
- Located in Terminal 1, 2, and 4.
- Metro: Line 8
- Bus: Lines 101, 200, Exprés-203
- Train: Cercanías C1, C10
More options for your journey from Panama City to Madrid
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