- Must visit
Museo Nacional de Bellas Artes
Chile's leading fine arts museum in a landmark 1910 palace. Visit for national and international art plus one of the city's most beautiful interiors.
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Journey information
Overview: Panama City to Santiago flight
Panama
Chile
Flights from Panama City to Santiago depart on average 26 times per day, taking around 8h 24m. Cheap flight tickets for this journey start at €622 if you book in advance.
There are 6 flights per day. The earliest flight runs at 20:10, the last at 20:10. The fastest flight covers the 2993 miles (4818 km) distance in 6h 31m. September is the cheapest month to fly.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 2993 miles (4818 km) |
Average flight duration 8h 24m |
Cheapest ticket price €622 |
Flights per day 26 |
Direct flights 6 |
Fastest flight 6h 31m |
First flight 8:10 PM |
Last flight 8:10 PM |
Cheapest Month Sep |
Cheapest Day Wed |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Frequently asked questions about your Panama City to Santiago trip
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Panama City to Santiago.
Cheap plane tickets from Panama City to Santiago can start from as little as €622 when you book in advance. The average flight ticket price for Panama City to Santiago is €720 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The earliest flight from Panama City to Santiago leaves at 8:10 PM. Plan your trip with the Journey Planner from Omio.
The latest flight from Panama City to Santiago leaves at 8:10 PM.
Yes, there are 6 direct flights a day from Panama City to Santiago with COPA Airlines. Schedules can vary on holidays or weekends with fewer direct flights.
Why should you book Panama City to Santiago flights with Omio?
Avianca as well as COPA Airlines offer flights services from Panama City to Santiago.
Omio is an official ticket reseller for all your travel options from Panama City to Santiago.
Why book with Omio vs Avianca?
- Compare with other providers: On Omio, you can not only buy tickets for Avianca, but also compare tickets for the likes of COPA Airlines to find the best option for your trip from Panama City to Santiago.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
Why book with Omio over Trip, Kayak or Edreams?
- Compare with other providers: On Omio, you can also compare tickets for the likes of COPA Airlines to find the best option for your trip from Panama City to Santiago.
Airlines: Avianca, COPA Airlines from Panama City to SantiagoFind the best flights between Panama City to Santiago with Omio's travel partners Avianca, COPA Airlines from €622. We can find you the best deals, schedules and tickets when comparing and booking the best trip.
Avianca
About
Avianca is the national and largest airline of Colombia, and one of the oldest airlines in the world, tracing its origins back to 1919. It serves as the flagship of a group of airlines across the Americas, operating under a codesharing system. Avianca boasts an extensive network of destinations throughout the Americas, with its main hub located at El Dorado International Airport in Bogotá. The airline is a member of the Star Alliance, offering various classes of service from economy to business and first-class. Its fleet includes modern aircraft such as the Airbus A320 family, Airbus A330, and Boeing 787 Dreamliner.
Luggage & cancellation policy
Average Avianca Duration
7h 30m
Cheapest Avianca Price
€622
Avianca frequency
20 a day
Luggage included
1 carry-on bag (10kg) and 1 personal item included in most fares
Additional luggage
Additional checked baggage can be purchased, up to 32kg per piece
Cancellation Policy
Refunds available depending on fare type, some tickets non-refundable. Changes permitted with fee.
Pregnant on board
Pregnant women can travel up to 36 weeks for single pregnancies, 32 weeks for multiple pregnancies. Medical certificate required after 28 weeks
Unaccompagned minor
Children aged 5-17 can travel as unaccompanied minors with additional service fee. Must be booked at least 48 hours in advance
Amenities on board the airplane
Wifi
Food sold onboard
USB plugs
Accessibility
Assistance available for passengers with reduced mobility, must be requested 48h before flight
Pets
Small pets in cabin, max 8kg including carrier
Entertaiment on board
COPA Airlines
About
Copa Airlines, Panama's flag carrier, was founded in 1947 and is headquartered in Panama City with its main hub at Tocumen International Airport. The airline operates as a full-service carrier, connecting North, Central, and South America, as well as the Caribbean. As a member of the Star Alliance, Copa Airlines serves over 80 destinations in more than 30 countries. The airline's fleet primarily consists of Boeing 737 aircraft, with some Embraer 190s for regional flights. Copa Airlines is recognized for its punctuality and its strategic "Hub of the Americas" at Tocumen, which consolidates passenger traffic for efficient service.
Luggage & cancellation policy
Average COPA Airlines Duration
6h 31m
Cheapest COPA Airlines Price
€805
COPA Airlines frequency
6 a day
Luggage included
1 carry-on bag (22 x 14 x 9 inches) and 1 personal item
Additional luggage
Additional checked bags can be purchased, fees vary by route
Cancellation Policy
Refundable tickets available for full refund, non-refundable tickets can be changed for fee
Pregnant on board
Up to 36 weeks for single pregnancy, 32 weeks for multiple. Medical certificate required after 28 weeks
Unaccompagned minor
Ages 5-11 must use Unaccompanied Minor service. Ages 12-17 optional. Service fee applies
Amenities on board the airplane
Wifi
Food sold onboard
USB plugs
Accessibility
Wheelchair assistance available with 48-hour advance notice
Pets
Small pets in cabin, must be in approved carrier under seat
Entertaiment on board
Companies, tickets, and onboard amenities between Panama City and Santiago
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
When taking a flight from Panama City to Santiago, you can count on Avianca, COPA Airlines for the best way to get you to Santiago. You can also check all possible airlines who offer a service between Panama City and Santiago and compare the amenities they offer before buying a plane ticket.
For international flights we recommend to arrive 2.5 to 3 hours before departure. Please check the website of your departure airport if in doubt. Some airports may offer booking time slots for security checks or offer additional information on when to get there based on time of day.
Most airlines permit carry-on bags that fit within specific dimensions (e.g., 22 x 14 x 9 inches or 56 x 36 x 23 cm), including handles and wheels. Bags must fit in the overhead bin or under the seat in front of you.
Many airlines impose weight limits, commonly ranging between 7 kg (15 lbs) and 12 kg (26 lbs). Typically, passengers are allowed one carry-on bag and one personal item (for example a purse, laptop bag, or backpack). Personal items must fit under the seat in front of you. Budget Airlines (like Ryanair or Wizz Air) have stricter size and weight limits, often requiring fees for larger carry-ons. Full-Service Airlines have more lenient policies, sometimes including more spacious dimensions or higher weight limits depending on your ticket class.
The list of items prohibited on an airplane varies by country and airline, but in general, the following items are not allowed in carry-on or checked baggage: Weapons and self-defence items, sharp objects, flammable materials, explosives, toxic substances, or liquids over 100ml (except for medications and baby essentials). In checked baggage, firearms (without authorization), explosives, large lithium batteries, and hazardous chemicals are prohibited. Electronic cigarettes must be in carry-on bags, while alcohol and dry ice have restrictions. Always check with your airline for specific regulations.
Complete guide to Santiago
Things to do in Santiago
Discover the best of Santiago — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Santiago trip today.
- Must visit
Museo de la Memoria y los Derechos Humanos
Compelling museum on human rights abuses during the dictatorship. Essential for understanding modern Chile through multimedia, testimony, and archives.
- Must visit
Museo Chileno de Arte Precolombino
Interactive pre-Columbian museum in a restored colonial building. Famous for Andean and Mesoamerican collections and clear, engaging interpretation.
- Must visit
Plaza de Armas
Santiago's historic main square, surrounded by key civic and religious buildings. Ideal for architecture, street life, and starting a downtown walk.
- Must visit
Parque Metropolitano de Santiago
Large urban park and hill complex with trails, gardens, pools, and lookouts. A signature Santiago experience for views and open-air recreation.
- Must visit
Lastarria
Leafy cultural district known for mansions, museums, and cafes nearby. Walk here for elegant architecture, galleries, and a relaxed urban atmosphere.
Empanada De Pino
Empanada de pino is Chile’s classic baked pastry filled with beef, onion, egg, olive, and raisins; a staple for fiestas patrias and everyday bakeries.
- Gluten-free
Pastel De Choclo
Pastel de choclo is a baked corn casserole with sweet corn topping over beef or chicken, onion, olives, and egg; a beloved central Chile comfort dish.
- Gluten-free
Cazuela
Cazuela is a traditional homemade broth with beef or chicken, pumpkin, potato, corn, and rice; valued as hearty Chilean family cooking.
Boragó
Refined restaurant in a restored mansion, celebrated for contemporary Chilean cuisine and polished fine dining service.
Fuente Alemana
Traditional Fuente de soda famed for oversized sandwiches, completos, and classic casual Santiago dining.
Liguria
Well-known neighborhood restaurant serving Chilean staples, seafood, and comforting local dishes in a relaxed setting.
Chilean peso ($)
Moderate for South America; hotels cost more than in Lima, but dining and metro stay reasonable for tourists.
Average meal costs
- Budget
- $6.000-$10.000 for fast food or casual lunch.
- Mid-range
- $12.000-$22.000 per person for a meal.
- Fine dining
- $35.000+ per person for upscale restaurants.
- Coffee
- $2.000-$3.500 for cappuccino.
Tipping culture
A 10% restaurant tip is customary and often suggested on the bill. Round up for cafes and taxis; tipping is not expected for short taxi rides.
RED
Get the appOfficial public transport app
Prices
- Single ticket
- $700
- Day pass
- $700
To the city center
Arturo Merino Benítez Airport -> Plaza de Armas, Santiago
- Distance
- 18 km
- Travel time
- 40 min
- Metro and buses in Santiago use the Bip! card. Bank card contactless payment is not generally accepted directly on Metro gates or buses.
- Airport buses connect the airport with Metro stations and the city center. Load enough balance on your Bip! card before peak hours to avoid queues.
Plan your visit to Santiago
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Santiago.
Chile uses the Chilean Peso (CLP) as its currency. Travelers generally find it convenient to use cards in urban areas and larger establishments, but cash is recommended for smaller shops, markets, and rural locations where card acceptance may be limited.
In Santiago, travelers should be cautious of pickpocketing and bag snatching, especially in crowded areas like public transport, markets, and tourist spots. Common scams include overcharging by taxi drivers who do not use meters and counterfeit currency. It's advisable to use authorized taxis or ride-hailing apps and remain vigilant with personal belongings to ensure safety.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
FAQs: Panama City to Santiago Flight
Find answers to the most common questions about traveling from Panama City to Santiago by flight. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest flight, the cheapest option, or tips for making the most of your visit at Santiago, this guide helps you travel smarter and with confidence.
Yes, you can take a between Panama City and Santiago.
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