Journey information
Overview: Panama City to Madrid flight
Flights from Panama City to Madrid depart on average 44 times per day, taking around 11h 22m. Cheap flight tickets for this journey start at $541 (€434) if you book in advance.
There are 1 flights per day. The earliest flight runs at 00:10, the last at 23:55. The fastest flight covers the 5071 miles (8162 km) distance in 9h 35m. June is the cheapest month to fly.
Distance 5071 miles (8162 km) |
Average flight duration 11h 22m |
Cheapest ticket price $541 (€434) |
Flights per day 44 |
Direct flights 1 |
Fastest flight 9h 35m |
First flight 12:10 AM |
Last flight 11:55 PM |
Cheapest Month Jun |
Cheapest Day Mon |
High Season Oct - Dec |
Low Season Jul - Sep |
Busiest Day Wed |
Least Busy Day Sun |
Best time to book 49 days |
The cheapest and fastest flights from Panama City to Madrid
Cheapest price
$845
Average price
$1797
Fastest journey
9 h 50 m
Average duration
12 h 39 m
Flights per day
51
Distance
8162 km
The best way to find a cheap flight ticket from Panama City to Madrid is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Panama City to Madrid will cost around $1797 if you buy it on the day, but the cheapest tickets can be found for only $845.
Of the 51 flights that leave Panama City for Madrid onThu, May 07, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, May 07 the direct flights cover the 8162 km distance in an average of 12 h 39 m but if you time it right, some flights will get you there in just 9 h 50 m .
On Thu, May 07 the longest flights will take 14 h 20 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
IB4369+
IB3381:49 PM16h01Panama City12:50 PMMadrid Barajas Airport$8451One-way1 transfer
UA727 · UA519:45 AM16h15Panama City9:00 AMMadrid Barajas Airport$9521One-way1 transfer
UA727 · UA8838 · UA93589:45 AM19h35Panama City12:20 PMMadrid Barajas Airport$10001One-way2 transfers
UA727 · UA42 · UA92299:45 AM23h25Panama City4:10 PMMadrid Barajas Airport$10001One-way2 transfers
UA7156 · UA2609:13 AM15h52Panama City8:05 AMMadrid Barajas Airport$10141One-way1 transfer
UX568:25 PM9h50Panama City1:15 PMMadrid Barajas Airport$13481One-way0 transfers
AV41 · AV464:25 AM12h55Panama City12:20 AMMadrid Barajas Airport$27501One-way1 transfer
AV59 · AV2610:10 AM13h00Panama City6:10 AMMadrid Barajas Airport$27501One-way1 transfer
AV57 · AV105:55 PM13h10Panama City2:05 PMMadrid Barajas Airport$27501One-way1 transfer
AF491 · AF11009:55 PM14h20Panama City7:15 PMMadrid Barajas Airport$12961One-way1 transfer
Live departures
Panama City to Madrid flight times
The table below shows live departures for Panama City to Madrid flights for today, Wednesday, May 6. You can also manually refresh the results below to see updated flight journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 2:30 AM Panama City | 9h35 | 12:05 PM Madrid | 0 transfersDirect | |
![]() | 7:55 AM Panama City | 14h25 | 10:20 PM Madrid | 0 transfersDirect | |
![]() | 7:55 PM Panama City | 16h30 | 12:25 PM Madrid | 0 transfersDirect | |
![]() | 11:20 PM Panama City | 10h05 | 9:25 AM Madrid | 0 transfersDirect | |
![]() | 11:40 PM Panama City | 19h00 | 6:40 PM Madrid | 0 transfersDirect |
Find all the dates and times for this journey
Compare prices and tickets Panama City to Madrid by flight
Compare flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
May 07
May 08
May 09
May 10
May 11
May 12
May 13
Why should you book Panama City to Madrid flights with Omio?
Why book with Omio vs Air Europa?
- Compare with other providers: On Omio, you can not only buy tickets for Air Europa, but also compare tickets for the likes of Iberia, American Airlines, Air France or KLM to find the best option for your trip from Panama City to Madrid.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
Why book with Omio over Edreams, Trip or Kayak?
- Compare with other providers: On Omio, you can also compare tickets for the likes of Iberia, American Airlines, Air France or KLM to find the best option for your trip from Panama City to Madrid.
Airlines: Air Europa, Iberia, American Airlines, Air France, KLM from Panama City to MadridFind the best flights between Panama City to Madrid with Omio's travel partners Air Europa, Iberia, American Airlines, Air France, KLM from $541 (€434). We can find you the best deals, schedules and tickets when comparing and booking the best trip.
American Airlines
Air France
Air Europa
Iberia
KLM
FAQs: Panama City to Madrid Flight
Find answers to the most common questions about traveling from Panama City to Madrid by flight. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest flight, the cheapest option, or tips for making the most of your visit at Madrid, this guide helps you travel smarter and with confidence.

- San Isidro Festival, a celebration honoring the patron saint of Madrid with parades and traditional music
- Madrid Pride, one of the largest LGBTQ+ pride events in Europe featuring a colorful parade
- La Paloma Festival, a local festival celebrating the Virgin of La Paloma with street parties and cultural activities
- Madrid Fashion Week, a showcase of the latest trends and designs from Spanish and international fashion designers.
- Prado Museum, a renowned art museum housing European masterpieces from the 12th to the early 20th century
- Royal Palace of Madrid, the official residence of the Spanish royal family with opulent architecture and historical artifacts
- Retiro Park, a large and popular park in the city center featuring sculptures, a lake, and the Crystal Palace
- Plaza Mayor, a grand square surrounded by historic buildings and a hub for cultural events and markets
- Gran Vía, a bustling street known for its shopping, theaters, and vibrant nightlife.
- Epiphany, January, a traditional celebration with parades and the Three Kings' Day festivities
- Semana Santa, April, a significant religious observance with processions and cultural significance
- Assumption of Mary, August, a public holiday with various local celebrations and events
- National Day of Spain, October, commemorating the country's history with patriotic displays and activities.
- Puerta del Sol, a bustling public square known for its iconic clock and vibrant atmosphere
- Mercado de San Miguel, a historic market offering a variety of gourmet foods and traditional Spanish delicacies
- Explore the vibrant nightlife in the Malasaña district, known for its eclectic bars and live music venues
- Attend a flamenco show to experience traditional Spanish dance and music
- Visit the Santiago Bernabéu Stadium, home to Real Madrid, for a tour or to catch a football match.
popular airports
Popular airports from Panama City to Madrid
- Free Wi-Fi available throughout the airport.
- Shops located in duty-free area, including local crafts and intertiol brands.
- Parking available, short-term and long-term, approximately 0.95€ ($1) per hour.
- Various restaurants in food court, including local cuisine and fast food
- Available outside the terminal.
- Elevators, ramps
- Available throughout the airport.
- Hotels nearby, such as Crowne Plaza Pama Airport.
- Showers available in some lounges, access may require lounge entry fee.
- Several lounges available, including Copa Club.
- Lost and Found located in the main terminal.
- Car rental services available from major providers like Hertz and Avis
- Metro Line 2, Estación Corredor Sur, 24 km
- Free Wi-Fi available throughout the airport.
- Shops in all terminals, including duty-free and fashion brands.
- Parking available at all terminals, approximately 2.5€ per hour.
- Available outside the terminal.
- Ramps, assistance.
- Available throughout the airport.
- Yes
- Lounges available in all terminals, including VIP lounges.
- Located in Terminal 1, 2, and 4.
- Metro: Line 8
- Bus: Lines 101, 200, Exprés-203
- Train: Cercanías C1, C10
More options for your journey from Panama City to Madrid
Here are some other resources that might have the information you need

