- Must visit
Museo del Canal Interoceánico de Panamá
Museum in a former convent in Casco Antiguo presenting pre-Columbian, colonial, and modern artifacts for a concise overview of Panama's history.
The best way to find a cheap flight ticket from Madrid to Panama City is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Madrid to Panama City will cost around €1,140 if you buy it on the day, but the cheapest tickets can be found for only €516.
On Mon, Nov 02, we found 90 flights from Madrid to Panama City, including 1 direct services.
On Mon, Nov 02 the direct flights cover the 8162 km distance in an average of 13 h 19 m but if you time it right, some flights will get you there in just 10 h 35 m .
On Mon, Nov 02 the longest flights will take 14 h 45 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
AV27 · AV60
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AV27 · AV40
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UX55
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IB337+
IB4462
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AF1401 · AF474
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UX55
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AV27 · AV56
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AV47 · AV58
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AV11 · AV40
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IB243+
IB7730
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Flights from Madrid to Panama City depart on average 47 times per day, taking around 14h 5m. Cheap flight tickets for this journey start at €278 if you book in advance.
There are 1 flights per day. The earliest flight runs at 00:10, the last at 23:55. The fastest flight covers the 5071 miles (8162 km) distance in 10h 35m. February is the cheapest month to fly.
Plan this route
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Madrid to Panama City.
The table below shows live departures for Madrid to Panama City flights for today, Sunday, November 1. You can also manually refresh the results below to see updated flight journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
AF1401+ AF8374 · AF8225 | 6:00 AM Madrid Barajas Airport | 16h30 | 4:30 PM Panama City | 2 transfers | |
AF1401 · AF474 | 6:00 AM Madrid Barajas Airport | 20h20 | 8:20 PM Panama City | 1 transfer | |
LH1117 · LH542+ LH5480 | 6:00 AM Madrid Barajas Airport | 30h39 | 6:39 AM Panama City | 2 transfers | |
KL1500 · KL1407+ KL2296 | 6:05 AM Madrid Barajas Airport | 20h15 | 8:20 PM Panama City | 2 transfers | |
KL1500 · KL757 | 6:05 AM Madrid Barajas Airport | 16h25 | 4:30 PM Panama City | 1 transfer | |
KL1500+ KL2007 · KL2296 | 6:05 AM Madrid Barajas Airport | 20h15 | 8:20 PM Panama City | 2 transfers | |
KL1500+ KL2003 · KL2296 | 6:05 AM Madrid Barajas Airport | 20h15 | 8:20 PM Panama City | 2 transfers | |
AV27 · AV58 | 6:35 AM Madrid Barajas Airport | 32h15 | 8:50 AM Panama City | 1 transfer | |
AV27 · AV56 | 6:35 AM Madrid Barajas Airport | 13h25 | 2:00 PM Panama City | 1 transfer | |
AV27 · AV60 | 6:35 AM Madrid Barajas Airport | 16h20 | 4:55 PM Panama City | 1 transfer | |
AV27 · AV40 | 6:35 AM Madrid Barajas Airport | 24h25 | 1:00 AM Panama City | 1 transfer | |
KL3390+ KL1407+ KL2296 | 7:00 AM Madrid Barajas Airport | 19h20 | 8:20 PM Panama City | 2 transfers | |
KL3390+ KL757 | 7:00 AM Madrid Barajas Airport | 15h30 | 4:30 PM Panama City | 1 transfer | |
AV6028 · AV19 · AV40 | 7:05 AM Madrid Barajas Airport | 23h55 | 1:00 AM Panama City | 2 transfers | |
UX7701+ AV19 · AV40 | 7:30 AM Madrid Barajas Airport | 23h30 | 1:00 AM Panama City | 2 transfers | |
AF1001 · AF474 | 10:00 AM Madrid Barajas Airport | 16h20 | 8:20 PM Panama City | 1 transfer | |
KL1502 · KL757 | 10:50 AM Madrid Barajas Airport | 35h40 | 4:30 PM Panama City | 1 transfer | |
AV183 · AV58 | 10:50 AM Madrid Barajas Airport | 28h00 | 8:50 AM Panama City | 1 transfer | |
AV183 · AV60 | 10:50 AM Madrid Barajas Airport | 36h05 | 4:55 PM Panama City | 1 transfer | |
AV183 · AV40 | 10:50 AM Madrid Barajas Airport | 20h10 | 1:00 AM Panama City | 1 transfer | |
AV183 · AV56 | 10:50 AM Madrid Barajas Airport | 33h10 | 2:00 PM Panama City | 1 transfer | |
UA261 · UA7065 | 11:00 AM Madrid Barajas Airport | 25h13 | 6:13 AM Panama City | 1 transfer | |
UA261 · UA7126 | 11:00 AM Madrid Barajas Airport | 32h31 | 1:31 PM Panama City | 1 transfer | |
IB257 | 12:00 PM Madrid Barajas Airport | 11h05 | 5:05 PM Panama City | 0 transfersDirect | |
KL1504 · KL757 | 1:05 PM Madrid Barajas Airport | 33h25 | 4:30 PM Panama City | 1 transfer | |
LH1113 · LH542+ LH5480 | 1:25 PM Madrid Barajas Airport | 47h14 | 6:39 AM Panama City | 2 transfers | |
UA8463 · UA8687 · UA7082 | 1:25 PM Madrid Barajas Airport | 30h36 | 2:01 PM Panama City | 2 transfers | |
UA8463 · UA8687 · UA7173 | 1:25 PM Madrid Barajas Airport | 37h12 | 8:37 PM Panama City | 2 transfers | |
UX55 | 3:10 PM Madrid Barajas Airport | 10h35 | 7:45 PM Panama City | 0 transfersDirect | |
AV11 · AV60 | 4:20 PM Madrid Barajas Airport | 30h35 | 4:55 PM Panama City | 1 transfer | |
AV11 · AV40 | 4:20 PM Madrid Barajas Airport | 14h40 | 1:00 AM Panama City | 1 transfer | |
AV11 · AV58 | 4:20 PM Madrid Barajas Airport | 22h30 | 8:50 AM Panama City | 1 transfer | |
AV11 · AV56 | 4:20 PM Madrid Barajas Airport | 27h40 | 2:00 PM Panama City | 1 transfer | |
AF1601 · AF474 | 4:25 PM Madrid Barajas Airport | 33h55 | 8:20 PM Panama City | 1 transfer | |
IB337+ IB4462 | 4:30 PM Madrid Barajas Airport | 27h06 | 1:36 PM Panama City | 1 transfer | |
KL1506 · KL757 | 5:00 PM Madrid Barajas Airport | 29h30 | 4:30 PM Panama City | 1 transfer | |
LH1115 · LH542+ LH5480 | 5:15 PM Madrid Barajas Airport | 43h24 | 6:39 AM Panama City | 2 transfers | |
AF1801 · AF474 | 6:50 PM Madrid Barajas Airport | 31h30 | 8:20 PM Panama City | 1 transfer | |
AV6072 · AV19 · AV58 | 7:10 PM Madrid Barajas Airport | 43h40 | 8:50 AM Panama City | 2 transfers | |
AV6072 · AV19 · AV40 | 7:10 PM Madrid Barajas Airport | 35h30 | 12:40 AM Panama City | 2 transfers | |
AV6083 · AV19 · AV58 | 8:00 PM Madrid Barajas Airport | 42h50 | 8:50 AM Panama City | 2 transfers | |
AV6083 · AV19 · AV40 | 8:00 PM Madrid Barajas Airport | 34h40 | 12:40 AM Panama City | 2 transfers | |
AF1101+ AF8374 · AF8225 | 8:05 PM Madrid Barajas Airport | 26h25 | 4:30 PM Panama City | 2 transfers | |
AF1101 · AF1340+ AF8225 | 8:05 PM Madrid Barajas Airport | 26h25 | 4:30 PM Panama City | 2 transfers | |
AF1101 · AF1240+ AF8225 | 8:05 PM Madrid Barajas Airport | 26h25 | 4:30 PM Panama City | 2 transfers | |
AF1101 · AF474 | 8:05 PM Madrid Barajas Airport | 30h15 | 8:20 PM Panama City | 1 transfer | |
KL1508 · KL757 | 8:30 PM Madrid Barajas Airport | 26h00 | 4:30 PM Panama City | 1 transfer | |
| Monday, November 2 | |||||
AV47 · AV56 | 1:20 AM Madrid Barajas Airport | 18h40 | 2:00 PM Panama City | 1 transfer | |
AV47 · AV40 | 1:20 AM Madrid Barajas Airport | 29h20 | 12:40 AM Panama City | 1 transfer | |
AV47 · AV60 | 1:20 AM Madrid Barajas Airport | 21h35 | 4:55 PM Panama City | 1 transfer | |
AV47 · AV58 | 1:20 AM Madrid Barajas Airport | 13h30 | 8:50 AM Panama City | 1 transfer | |
This is the last flight of the day. | |||||
Find all the dates and times for this journey
Flights from Madrid to Panama City with Avianca, KLM, and United. Flights with a stop available on this route with Avianca, KLM, and United. Use the details below to compare onboard facilities.
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
Discover the best of Panama City — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Panama City trip today.
Museum in a former convent in Casco Antiguo presenting pre-Columbian, colonial, and modern artifacts for a concise overview of Panama's history.
Modern museum by Frank Gehry exploring biodiversity, geology, and regional ecosystems through interactive exhibits on the Amador Causeway.
Contemporary art museum in Ancón with rotating exhibitions by Panamanian and international artists, plus a sculpture garden and canal views nearby.
Atmospheric old quarter of plazas, churches, rooftops, and restored streets. Ideal for walking, architecture, and sunset views over the bay.
Long waterfront promenade popular for walking, cycling, skyline views, and breezes. A classic urban outing linking neighborhoods along the bay.
Scenic causeway built with canal excavation rock, known for bay views, marinas, bike rides, and easy access to museums and the cruise terminal area.
Corn dough stuffed with meat, wrapped in banana leaves and boiled. A festive Panamanian staple with strong Afro-Caribbean and rural traditions.
Shredded chicken and rice soup thickened with vegetables and herbs. A comforting national favorite often served at family meals and celebrations.
Fried corn dough topped with stewed beef or chicken. A beloved street snack and breakfast item rooted in Panama’s corn-based cooking.
Upscale dining in Casco Viejo focused on refined Panamanian ingredients and contemporary local cuisine in an elegant setting.
Traditional Panamanian restaurant serving local classics in a casual setting, popular for breakfast, soups, and home-style dishes.
Historic seafood market complex known for fresh ceviche and casual local seafood counters with lively daytime atmosphere.
Moderate for the region: hotels and dining cost more than many Central American capitals, but local transit and casual meals stay fairly affordable for tourists.
Service may be included. If not, tip 10% in restaurants. Round up or add a little for taxis. Small tips are appreciated in cafes.
Official public transport app
Aeropuerto Station -> Albrook, Panama City
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Panama City.
Find answers to the most common questions about traveling from Madrid to Panama City by flight. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest flight, the cheapest option, or tips for making the most of your visit at Panama City, this guide helps you travel smarter and with confidence.

Most Madrid to Panama City flights use the Madrid Barajas Airport to Panama City airport pair. Use this guide to compare Madrid and Panama City airports on this route, check city-centre transport, alongside checking practicalities like airport facilities and services.
Madrid Barajas Airport is 12 km from Madrid city centre. Public transport options include:
Madrid Barajas Airport has practical services for this route, including Wifi, Shopping, Parking, ATM, Taxis, Accessibility, WC, Shower, Lounge, and Lost and Found Office.
Free Wi-Fi available throughout the airport. ATMs are located in all terminals.
Lost and found is available at the station.
Available at Madrid Barajas Airport: Parking, Taxis, WC.
Accessibility facilities are available at Madrid Barajas Airport: Ramps, assistance.
Panama City is 1 km from Panama City city centre. Public transport options include:
Panama City has practical services for this route, including Wifi, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Shower, Lounge, Lost and Found Office, and Car Rental.
Food options include: Various restaurants in food court, including local cuisine and fast food
Free Wi-Fi available throughout the airport. ATMs are located in all terminals.
Lost and found is available at the station.
Available at Panama City: Parking, Taxis, WC.
Available at Panama City: Car Rental.
Accessibility facilities are available at Panama City: Elevators, ramps.
Nearby hotels include Hotels nearby, such as Crowne Plaza Pama Airport..
See which airports are used for flights between Madrid and Panama City, including airport details.