- Must visit
National Museum
Major museum of Czech history and natural sciences in a monumental Neo-Renaissance building overlooking Wenceslas Square.
Buses from Wiesbaden to Prague run on average 5 times per day, taking around 13h 46m. Cheap bus tickets for this journey start at €33 but you can travel from only €26 by train.
The earliest bus runs at 02:30, the last at 23:55. The fastest bus covers the 273 miles (440 km) distance in 12h 20m.
Distance 273 miles (440 km) |
Average bus duration 13h 46m |
Cheapest ticket price €33 |
Buses per day 5 |
Fastest bus 12h 20m |
First bus 2:30 AM |
Last bus 11:55 PM |
Cheapest Month Jul |
Cheapest Day Tue |
High Season Apr - Jun |
Low Season Jul - Sep |
Busiest Day Fri |
Least Busy Day Mon |
Best time to book 1 day |
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Wiesbaden to Prague.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 02:35AM | Arrival Time 06:00PM | Duration 15h25 | Departure days Sun | Cheapest price €53 |
Operator FlixBus | Departure Time 04:35AM | Arrival Time 08:00PM | Duration 15h25 | Departure days Mon, Wed, Thu, Fri | Cheapest price €41 |
Operator FlixBus | Departure Time 06:45AM | Arrival Time 09:50PM | Duration 15h05 | Departure days Mon, Fri | Cheapest price €44 |
Operator FlixBus | Departure Time 11:10AM | Arrival Time 01:15AM | Duration 14h05 | Departure days Sun | Cheapest price €50 |
Operator FlixBus | Departure Time 01:10PM | Arrival Time 03:15AM | Duration 14h05 | Departure days Thu, Fri | Cheapest price €45 |
Operator RegioJet a.s. | Departure Time 10:00PM | Arrival Time 04:48AM | Duration 6h48 | Departure days Mon, Wed, Thu, Fri | Cheapest price €30 |
Operator RegioJet a.s. | Departure Time 10:30PM | Arrival Time 04:48AM | Duration 6h18 | Departure days Mon, Wed, Thu, Fri | Cheapest price €26 |
The table below shows live departures for Wiesbaden to Prague buses for today, Monday, November 2. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
(Amsterdam -> Prague) | 10:00 PM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 6h48 | 4:48 AM Praha, ÚAN Florenc | 0 transfersDirect | |
(Amsterdam -> Prague) | 10:30 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 6h18 | 4:48 AM Praha, ÚAN Florenc | 0 transfersDirect | |
This is the last bus of the day. | |||||
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Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
Discover the best of Prague — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Prague trip today.
Major museum of Czech history and natural sciences in a monumental Neo-Renaissance building overlooking Wenceslas Square.
Well-curated Jewish history museum across several historic sites. Important for understanding Prague's Jewish heritage and resilience.
Leading Czech art museum with medieval to modern works in a grand historic palace. Essential for fine art and decorative arts lovers.
Historic square at Prague's core, surrounded by Gothic and Baroque landmarks. A must for first-time visitors and classic city views.
Lively boulevard of Czech modern history, lined with shops and major buildings. Worth visiting for atmosphere and historic significance.
Romantic quarter of palaces, lanes, and church domes beneath Prague Castle. Ideal for wandering, photography, and quieter historic charm.
Slow-braised beef in a creamy root-vegetable sauce, usually served with bread dumplings. A classic Czech Sunday dish strongly linked to Bohemian home cooking.
Crisp roasted pork knuckle, often served with mustard, horseradish, and pickles. A hearty pub staple popular with Czech beer culture.
Roast pork with sauerkraut and dumplings. This iconic Czech combination is a cornerstone of traditional pub and family meals.
Traditional Czech restaurant and brewery by Prague Castle, praised for roast meats, dumplings, and polished historic interiors.
Upscale restaurant focused on Czech ingredients and game, with sophisticated service in an Art Nouveau municipal house setting.
Elegant Michelin-starred restaurant known for modern Czech tasting menus in a refined setting near the Vltava.
Moderate for Europe: transit is cheap, casual meals are reasonable, and hotels in the center can raise daily costs in peak season.
Service is often not included. Tip about 5-10% in restaurants, round up for cafes, and round up or add about 10% for taxis if service is good.
Official public transport app
Prague Central Train Station -> Wenceslas Square
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Prague.
Find answers to the most common questions about traveling from Wiesbaden to Prague by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

Most Wiesbaden to Prague buses use the Wiesbaden, Busbahnhof to Praha, ÚAN Florenc station pair, with some services arriving at Praha, Hlavní Nádraží. Use this guide to compare Wiesbaden and Prague bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Wiesbaden, Busbahnhof is 1 km from Wiesbaden city centre. Public transport options include:
Wiesbaden, Busbahnhof has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Several nearby eateries and cafes.
Wi-Fi is available at Wiesbaden, Busbahnhof. ATMs are available at Wiesbaden, Busbahnhof.
Ticket office support is available at Wiesbaden, Busbahnhof.
Available at Wiesbaden, Busbahnhof: Parking, Taxis, WC.
Accessibility facilities are available at Wiesbaden, Busbahnhof: Wheelchair accessible ramps present.
Praha, ÚAN Florenc is 1 km from Prague city centre. Public transport options include:
Praha, ÚAN Florenc has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafeteria Florenc (in the station), Bistro Florenc (0.2 km), Restaurace U Rozvařilů (0.5 km).
Free Wi-Fi. ATMs are located inside the station, offering multiple currency options.
Ticket office support is available at Praha, ÚAN Florenc.
Available at Praha, ÚAN Florenc: Parking, Taxis, WC.
Accessibility facilities are available at Praha, ÚAN Florenc: Elevators, ramps.
Praha, Hlavní Nádraží is 1 km from Prague city centre. Public transport options include:
Praha, Hlavní Nádraží has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Czech Bistro (in the station), Fast Food Express (in the station), Bohemian Café (0.2 km).
Free Wi-Fi. ATMs are located near the main entrance and ticketing area.
Ticket office support is available at Praha, Hlavní Nádraží.
Available at Praha, Hlavní Nádraží: Parking, Taxis, WC.
Accessibility facilities are available at Praha, Hlavní Nádraží: Elevators, ramps.
Praha, M. Horákové (Hradčanská) is 1 km from Prague city centre. Public transport options include:
Praha, M. Horákové (Hradčanská) has practical services for this route, including Taxis.
Available at Praha, M. Horákové (Hradčanská): Taxis.
Check bus stations information for Wiesbaden and Prague, including where buses depart and arrive on this route.
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