Travel Information
Compare bus, train, and flight for Wiesbaden to Prague
Omio recommends booking the train as it is the most popular option from Wiesbaden to Prague among Omio's users. If you are prioritising price take the bus with prices starting from $32. For those with little time consider booking a train which can get you there in 8h 11m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a bus costs an average of $32, and a train costs an average of $44.
Distance: 273 miles (440 km)
Compare train with
Most popular Train | Bus | Driving |
|---|---|---|
$108 Average price | $47 Average price Cheapest | $107 Average price (fuel + tolls) |
8h 41m Average total duration Fastest 8h 11m Onboard + 30m Additional time* | 10h 58m Average total duration 10h 28m Onboard + 30m Additional time* | 5h 41m Average total duration (door-to-door) |
0.1 - 0.4kg CO2 emissions Lowest | 0.4 - 1.1kg CO2 emissions | - CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Wiesbaden to Prague:
A bus is $61 (€49) less than a train for this route with tickets for a train from Wiesbaden to Prague costing on average $108 (€87).
A bus is $169 (€137) less than a flight for this route with tickets for a flight from Wiesbaden to Prague costing on average $216 (€175).
Other travel options to Prague take longer:
Train takes on average 8h 11m.
Bus takes on average 10h 28m.
Travel optionsfrom Wiesbaden to Prague
How to get from Wiesbaden to Prague by train, bus or flight.
Our recommendation
The best way to travel from Wiesbaden to Prague is by taking a bus because it’s the best combination of price and speed.
(Amsterdam -> Prague)10:30 PM6h18Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof)4:48 AMPraha, ÚAN Florenc$321One-way0 transfers
Cheapest
(Amsterdam -> Prague)10:30 PM6h18Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof)4:48 AMPraha, ÚAN Florenc$321One-way0 transfers
Fastest
DE44118:25 PM1h00Frankfurt am Main Airport9:25 PMPrague Vaclav Havel Airport$1821One-way0 transfers
Other options
ICE 692 · IC 2443 · RJ 383+
250099:32 AM7h53Wiesbaden Hbf5:25 PMPrague hlavní nádraží$821One-way3 transfers
ICE 621 · 3569+
359+
2506110:02 AM8h19Wiesbaden Hbf6:21 PMPrague hlavní nádraží$821One-way3 transfers
ICE 2597 · S1 · 28008 · R 6898:32 AM8h38Wiesbaden Hbf5:10 PMPrague hlavní nádraží$941One-way4 transfers
(Amsterdam -> Prague)10:00 PM6h48Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)4:48 AMPraha, ÚAN Florenc$321One-way0 transfers
FlixBus · FlixBus1:10 PM18h00Wiesbaden, Busbahnhof7:10 AMPraha, ÚAN Florenc$521One-way1 transfer
FlixBus · FlixBus1:10 PM14h05Wiesbaden, Busbahnhof3:15 AMPrague, Central Train Station$531One-way1 transfer
DE440910:00 AM1h00Frankfurt am Main Airport11:00 AMPrague Vaclav Havel Airport$1821One-way0 transfers
DE44073:00 PM1h00Frankfurt am Main Airport4:00 PMPrague Vaclav Havel Airport$2271One-way0 transfers
KL1361+
KL18226:40 PM3h55Frankfurt am Main Airport10:35 PMPrague Vaclav Havel Airport$2651One-way1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
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FAQs: Travel from Wiesbaden to Prague
Travel to Prague easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Wiesbaden to Prague.

This is compared to other travel options from Wiesbaden to Prague:
A bus is $61 (€49) less than a train for this route with tickets for a train from Wiesbaden to Prague costing on average $108 (€87).
A bus is $169 (€137) less than a flight for this route with tickets for a flight from Wiesbaden to Prague costing on average $216 (€175).
Other travel options to Prague take longer:
Train takes on average 8h 11m.
Bus takes on average 10h 28m.
- Around 68 flights per day.
- Around 11 trains per day.
- Around 6 buses per day.
However, we recommend checking specific travel dates for your route between Wiesbaden and Prague as scheduled services by bus, train, and flight can vary by season or day of the week.
- Flights mostly depart from Frankfurt am Main Airport and arrive in Prague Vaclav Havel Airport.
- Trains mostly depart from Wiesbaden Hbf and arrive in Prague hlavní nádraží.
- Buses mostly depart from Wiesbaden, Busbahnhof and arrive in Praha, ÚAN Florenc.
- Travel with Deutsche Bahn, České dráhy, alex-Länderbahn und Vogtlandbahn-GmbH to go to Prague by train.
- Travel with FlixBus, BlaBlaCar to go to Prague by bus.
- 2 direct buses per day with BlaBlaCar.
Travelling from Wiesbaden to Prague: related information
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