Travel Information
Compare bus, train, and flight for Wiesbaden to Prague
Omio recommends booking the train as it is the most popular option from Wiesbaden to Prague among Omio's users. If you are prioritising price take the bus with prices starting from Kč667. For those with little time consider booking a train which can get you there in 8h 11m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a bus costs an average of Kč667, and a train costs an average of Kč926.
Distance: 273 miles (440 km)
Compare train with
Most popular Train | Bus | Driving |
|---|---|---|
Kč2253 Average price | Kč984 Average price Cheapest | Kč2237 Average price (fuel + tolls) |
8h 41m Average total duration Fastest 8h 11m Onboard + 30m Additional time* | 10h 58m Average total duration 10h 28m Onboard + 30m Additional time* | 5h 41m Average total duration (door-to-door) |
0.1 - 0.4kg CO2 emissions Lowest | 0.4 - 1.1kg CO2 emissions | - CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Wiesbaden to Prague:
A bus is Kč1268 less than a train for this route with tickets for a train from Wiesbaden to Prague costing on average Kč2253.
A bus is Kč3517 less than a flight for this route with tickets for a flight from Wiesbaden to Prague costing on average Kč4501.
Other travel options to Prague take longer:
Train takes on average 8h 11m.
Bus takes on average 10h 28m.
Travel optionsfrom Wiesbaden to Prague
How to get from Wiesbaden to Prague by train, bus or flight.
Our recommendation
The best way to travel from Wiesbaden to Prague is by taking a bus because it’s the best combination of price and speed.
(Amsterdam -> Prague)10:30 PM6h18Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof)4:48 AMPraha, ÚAN FlorencKč10271One-way0 transfers
Cheapest
(Amsterdam -> Prague)10:30 PM6h18Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof)4:48 AMPraha, ÚAN FlorencKč10271One-way0 transfers
Fastest
DE44118:25 PM1h00Frankfurt am Main Airport9:25 PMPrague Vaclav Havel AirportKč37291One-way0 transfers
Other options
ICE 527 · 3565+
357+
250558:02 AM8h19Wiesbaden Hbf4:21 PMPrague hlavní nádražíKč12361One-way3 transfers
ICE 1557 · RJ 3838:26 AM8h59Wiesbaden Hbf5:25 PMPrague hlavní nádražíKč20601One-way1 transfer
25007+
ICE 1557 · RJ 3838:32 AM8h53Wiesbaden Hbf5:25 PMPrague hlavní nádražíKč23431One-way2 transfers
(Amsterdam -> Prague)10:00 PM6h48Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)4:48 AMPraha, ÚAN FlorencKč10271One-way0 transfers
FlixBus · FlixBus6:45 AM15h05Wiesbaden, Busbahnhof9:50 PMPraha, ÚAN FlorencKč17631One-way1 transfer
FlixBus · FlixBus4:35 AM15h25Wiesbaden, Busbahnhof8:00 PMPraha, M. Horákové (Hradčanská)Kč19051One-way1 transfer
EW7722:25 PM1h10Cologne Bonn Airport3:35 PMPrague Vaclav Havel AirportKč22531One-way0 transfers
QS80372:25 PM1h10Cologne Bonn Airport3:35 PMPrague Vaclav Havel AirportKč37161One-way0 transfers
LH14004:45 PM1h00Frankfurt am Main Airport5:45 PMPrague Vaclav Havel AirportKč39991One-way0 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Wiesbaden to Prague
Travel to Prague easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Wiesbaden to Prague.

This is compared to other travel options from Wiesbaden to Prague:
A bus is Kč1268 less than a train for this route with tickets for a train from Wiesbaden to Prague costing on average Kč2253.
A bus is Kč3517 less than a flight for this route with tickets for a flight from Wiesbaden to Prague costing on average Kč4501.
Other travel options to Prague take longer:
Train takes on average 8h 11m.
Bus takes on average 10h 28m.
- Around 68 flights per day.
- Around 11 trains per day.
- Around 6 buses per day.
However, we recommend checking specific travel dates for your route between Wiesbaden and Prague as scheduled services by bus, train, and flight can vary by season or day of the week.
- Flights mostly depart from Frankfurt am Main Airport and arrive in Prague Vaclav Havel Airport.
- Trains mostly depart from Wiesbaden Hbf and arrive in Prague hlavní nádraží.
- Buses mostly depart from Wiesbaden, Busbahnhof and arrive in Praha, ÚAN Florenc.
- Travel with FlixBus, BlaBlaCar to go to Prague by bus.
- Travel with Deutsche Bahn, České dráhy, alex-Länderbahn und Vogtlandbahn-GmbH to go to Prague by train.
- 2 direct buses per day with BlaBlaCar.
Travelling from Wiesbaden to Prague: related information
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