Travel Information
Compare bus, train, and flight for Wiesbaden to Prague
Omio recommends booking the train as it is the most popular option from Wiesbaden to Prague among Omio's users. If you are prioritising price take the bus with prices starting from $34. For those with little time consider booking a flight which can get you there in 1h 0m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a bus costs an average of $34, and a flight costs an average of $67.
Distance: 273 miles (440 km)
Compare train with
Most popular Train | Bus | Flight |
|---|---|---|
$112 Average price | $51 Average price Cheapest | $209 Average price |
7h 58m Average total duration 7h 28m Onboard + 30m Additional time* | 10h 58m Average total duration 10h 28m Onboard + 30m Additional time* | 4h 0m Average total duration Fastest 1h 0m Onboard + 3h 0m Additional time* |
0.1 - 0.4kg CO2 emissions Lowest | 0.4 - 1.1kg CO2 emissions | 1.3 - 2.6kg CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Travel optionsfrom Wiesbaden to Prague
How to get from Wiesbaden to Prague by train, bus or flight.
Our recommendation
The best way to travel from Wiesbaden to Prague is by taking a bus because it’s the best combination of price and speed.
(Amsterdam -> Prague)10:30 PM6h15Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof)4:45 AMPrague, Central Train Station$521One-way0 transfers
Cheapest
(Amsterdam -> Prague)10:30 PM6h15Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof)4:45 AMPrague, Central Train Station$521One-way0 transfers
Fastest
DE44118:25 PM1h00Frankfurt am Main Airport9:25 PMPrague Vaclav Havel Airport$1881One-way0 transfers
Other options
25061+
ICE 621 · 3569+
35910:02 AM8h19Wiesbaden Hbf6:21 PMPrague hlavní nádraží$1981One-way3 transfers
ICE 1559 · RJ 17710:26 AM8h48Wiesbaden Hbf7:14 PMPrague-Holešovice$2401One-way1 transfer
25009+
ICE 692 · IC 2443 · RJ 3839:32 AM7h53Wiesbaden Hbf5:25 PMPrague hlavní nádraží$2401One-way3 transfers
(Amsterdam -> Prague)10:30 PM6h18Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof)4:48 AMPraha, ÚAN Florenc$521One-way0 transfers
(Amsterdam -> Prague)10:00 PM6h45Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)4:45 AMPrague, Central Train Station$521One-way0 transfers
(Amsterdam -> Prague)10:00 PM6h48Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)4:48 AMPraha, ÚAN Florenc$521One-way0 transfers
EW7722:00 PM1h10Cologne Bonn Airport3:10 PMPrague Vaclav Havel Airport$2031One-way0 transfers
DE44073:00 PM1h00Frankfurt am Main Airport4:00 PMPrague Vaclav Havel Airport$2041One-way0 transfers
QS80372:00 PM1h10Cologne Bonn Airport3:10 PMPrague Vaclav Havel Airport$3261One-way0 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
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FAQs: Travel from Wiesbaden to Prague
Travel to Prague easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Wiesbaden to Prague.

This is compared to other travel options from Wiesbaden to Prague:
A bus is $10 (€8) less than a train for this route with tickets for a train from Wiesbaden to Prague costing on average $43 (€35).
A bus is $33 (€26) less than a flight for this route with tickets for a flight from Wiesbaden to Prague costing on average $67 (€53).
Other travel options to Prague take longer:
Train takes on average 7h 50m.
Bus takes on average 6h 18m.
- Around 70 flights per day.
- Around 12 trains per day.
- Around 5 buses per day.
However, we recommend checking specific travel dates for your route between Wiesbaden and Prague as scheduled services by bus, train, and flight can vary by season or day of the week.
- Flights mostly depart from Frankfurt am Main Airport and arrive in Prague Vaclav Havel Airport.
- Trains mostly depart from Wiesbaden Hbf and arrive in Prague hlavní nádraží.
- Buses mostly depart from Wiesbaden, Busbahnhof and arrive in Praha, ÚAN Florenc.
- Travel with FlixBus, BlaBlaCar to go to Prague by bus.
- Travel with Deutsche Bahn, alex-Länderbahn und Vogtlandbahn-GmbH to go to Prague by train.
- Travel with Lufthansa to go to Prague by flight.
- 2 direct buses per day with BlaBlaCar.
Travelling from Wiesbaden to Prague: related information
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