- Must visit
Vatican Museums
World-famous papal museums with the Sistine Chapel, Raphael Rooms, and major classical collections.
Cheapest price on Sep 23
€10
Average ticket price on Sep 23
€16
Fastest journey on Sep 23
2 h 5 m
Average journey duration on Sep 23
2 h 36 m
Buses on Sep 23
5
Distance
123 km
The best way to find a cheap bus ticket from Spello to Rome is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Spello to Rome will cost around €16 if you buy it on the day, but the cheapest tickets can be found for only €10.
On Wed, Sep 23, we found 5 buses from Spello to Rome, including 3 direct services.
On Wed, Sep 23 the direct buses cover the 123 km distance in an average of 2 h 36 m but if you time it right, some buses will get you there in just 2 h 5 m .
On Wed, Sep 23 the slowest buses will take 3 h 30 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

Autobus PG031 · Regionale Veloce 4539
Regionale Veloce 4161 · treno 4161 effettuato con bus PG261
FlixBus
106
Autobus PG031 · Regionale Veloce 4539
FlixBus
Regionale Veloce 4161 · treno 4161 effettuato con bus PG261
106Omio recommends booking the train as it is the most popular option from Spello to Rome among Omio's users. If you are prioritising price, take the train, with an average ticket price of €16 For those with little time, consider booking a train, which has an average total journey time of 2h 47m. Average ticket prices depend on the travel mode: a train costs an average of €16, while a bus costs an average of €23.
Distance: 76 miles (123 km)
| Bus | Most popular Train | Driving |
|---|---|---|
€23 Average price | €16 Average price Cheapest | €32 Average price (fuel + tolls) |
3h 33m Average total duration 3h 3m Onboard + 30m Additional time* | 2h 47m Average total duration Fastest 2h 17m Onboard + 30m Additional time* | 2h 9m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Spello to Rome:
A train is €7 less than a bus for this route with tickets for a bus from Spello to Rome costing on average €23.
Other travel options to Rome take longer:
Bus takes on average 3h 3m.
Tickets start at around €23 compared to roughly €32 in fuel and tolls — a saving of about €9. The journey takes 3h 3m versus 2h 9m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by Marino Autolinee, Busitalia, FlixBus, Itabus.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Regionale | Departure Time 02:15AM | Arrival Time 04:23AM | Duration 2h08 | Departure days Thu | Cheapest price €13 |
Operator Regionale | Departure Time 03:15AM | Arrival Time 05:23AM | Duration 2h08 | Departure days Mon | Cheapest price €13 |
Operator Regionale | Departure Time 04:05AM | Arrival Time 06:15AM | Duration 2h10 | Departure days Tue, Wed | Cheapest price €13 |
Operator Regionale | Departure Time 04:15AM | Arrival Time 06:23AM | Duration 2h08 | Departure days Fri | Cheapest price €13 |
Operator Itabus | Departure Time 06:30AM | Arrival Time 08:50AM | Duration 2h20 | Departure days Sun | Cheapest price €21 |
Operator FlixBus | Departure Time 09:05AM | Arrival Time 11:40AM | Duration 2h35 | Departure days Tue, Wed, Fri, Sun | Cheapest price €12 |
Operator Itabus | Departure Time 10:15AM | Arrival Time 12:45PM | Duration 2h30 | Departure days Mon, Thu, Sat | Cheapest price €7 |
Operator Itabus | Departure Time 11:15AM | Arrival Time 01:45PM | Duration 2h30 | Departure days Mon, Thu, Sat | Cheapest price €7 |
Operator Itabus | Departure Time 12:30PM | Arrival Time 02:55PM | Duration 2h25 | Departure days Sun | Cheapest price €10 |
Operator Itabus | Departure Time 04:05PM | Arrival Time 06:30PM | Duration 2h25 | Departure days Sun | Cheapest price €10 |
Operator Marino Autolinee | Departure Time 08:10PM | Arrival Time 11:40PM | Duration 3h30 | Departure days Tue, Wed, Sun | Cheapest price €20 |
Operator Busitalia | Departure Time 09:25PM | Arrival Time 11:30PM | Duration 2h05 | Departure days Tue, Wed, Fri, Sun | Cheapest price €10 |
Operator Regionale | Departure Time 09:47PM | Arrival Time 12:29AM | Duration 2h42 | Departure days Tue, Wed | Cheapest price €13 |
The table below shows live departures for Spello to Rome buses for today, Tuesday, September 22. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
106 | 8:10 PM Foligno, Piazzale Unità D'Italia | 3h30 | 11:40 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
![]() | 9:25 PM Perugia, Piazza Partigiani | 2h05 | 11:30 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
Regionale Veloce 4161 · treno 4161 effettuato con bus PG261 | 9:47 PM Foligno station | 2h42 | 12:29 AM Rome Tiburtina | 1 transfer | |
| Wednesday, September 23 | |||||
Autobus PG031 · Regionale Veloce 4539 | 4:05 AM Foligno station | 2h10 | 6:15 AM Rome Tiburtina | 1 transfer | |
FlixBus | 9:05 AM Foligno, Viale Mezzetti | 2h35 | 11:40 AM Roma, Autostazione Tiburtina | 0 transfersDirect | |
Find all the dates and times for this journey
Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Spello to Rome run on average 4 times per day, taking around 3h 3m. Cheap bus tickets for this journey start at €6 if you book in advance.
There are 3 buses per day. The earliest bus runs at 00:20, the last at 23:05. The fastest bus covers the 76 miles (123 km) distance in 1h 50m.
Distance 76 miles (123 km) |
Average bus duration 3h 3m |
Cheapest ticket price €6 |
Buses per day 4 |
Direct buses 3 |
Fastest bus 1h 50m |
First bus 12:20 AM |
Last bus 11:05 PM |
Cheapest Month Aug |
Cheapest Day Thu |
High Season Apr - Jun |
Low Season Oct - Dec |
Busiest Day Mon |
Least Busy Day Sun |
Best time to book 70 days |
Discover the best of Rome — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Rome trip today.
World-famous papal museums with the Sistine Chapel, Raphael Rooms, and major classical collections.
Outstanding ancient sculpture and mosaic museum housed in the Palazzo dei Conservatori and Palazzo Nuovo.
Celebrated villa museum with Bernini sculptures, Caravaggio paintings, and refined garden setting.
Elegant Baroque square with Bernini's fountains, lively atmosphere, and superb people-watching.
Historic square and gathering place at the Spanish Steps, ideal for classic city views and strolls.
Charming cobbled neighborhood filled with ivy-clad lanes, churches, nightlife, and local character.
Classic Roman pasta with guanciale, egg yolk, Pecorino Romano, and black pepper. A city icon known for rich flavor without cream.
Roman pasta with guanciale, tomato, and Pecorino Romano. A traditional Lazio staple tied to shepherd cooking and bold savory flavor.
Pasta with guanciale, Pecorino Romano, and black pepper. Considered one of Rome's oldest pasta dishes and prized for its simplicity.
Three-Michelin-star dining by Niko Romito at Bulgari Hotel Roma, offering refined Italian tasting menus in an elegant setting.
Historic trattoria in Testaccio known for classic Roman pasta and quinto quarto dishes in a lively, traditional setting.
Popular casual spot famed for Roman-style pizzas and fried starters. Bustling atmosphere and a long-standing local reputation.
Moderate for Europe: stays in central Rome are pricey, but transit is cheap and meals range from affordable pizza to costly tourist-area dining.
Service may be included via coperto or servizio. Round up or leave 5-10% at restaurants if service is good; round up in taxis; small change is fine at cafés.
Official public transport app
Via Marsala, Rome -> Piazza Barberini, Rome
Find answers to the most common questions about traveling from Spello to Rome by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Rome, this guide helps you travel smarter and with confidence.

Most Spello to Rome buses use the Perugia, Via Cortonese (Fontivegge) to Roma, Autostazione Tiburtina station pair, with some services arriving at Roma, Autostazione (Metro Anagnina). Use this guide to compare Spello and Rome bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Roma, Autostazione Tiburtina is 4 km from Rome city centre. Public transport options include:
Roma, Autostazione Tiburtina has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Cafes and vending machines available.
Wi-Fi is available at Roma, Autostazione Tiburtina. ATMs are aTM available near ticket office.
Ticket office support is available at Roma, Autostazione Tiburtina.
Available at Roma, Autostazione Tiburtina: Parking, Taxis, WC.
Accessibility facilities are available at Roma, Autostazione Tiburtina: Wheelchair accessible entrances and facilities.
Here are some other resources that might have the information you need