- Must visit
Palazzo Abatellis - Regional Gallery of Sicily
Major art museum in a Gothic-Catalan palace, known for Sicilian medieval and Renaissance masterpieces including works by Antonello da Messina.
Flights from Siena to Palermo depart on average 19 times per day, taking around 1h 22m. Cheap flight tickets for this journey start at $21 (€17) if you book in advance.
There are 3 flights per day. The earliest flight runs at 05:30, the last at 23:55. The fastest flight covers the 374 miles (603 km) distance in 1h 15m. January is the cheapest month to fly.
Distance 374 miles (603 km) |
Average flight duration 1h 22m |
Cheapest ticket price $21 (€17) |
Flights per day 19 |
Direct flights 3 |
Fastest flight 1h 15m |
First flight 5:30 AM |
Last flight 11:55 PM |
Cheapest Month Jan |
Cheapest Day Sat |
High Season Apr - Jun |
Low Season Jan - Mar |
Busiest Day Wed |
Least Busy Day Wed |
Best time to book 42 days |
Cheapest price
$25
Average price
$25
Fastest journey
1 h 20 m
Average duration
1 h 20 m
Flights per day
1
Distance
603 km
The best way to find a cheap flight ticket from Siena to Palermo is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Siena to Palermo will cost around $25 if you buy it on the day, but the cheapest tickets can be found for only $25.
Of the 1 flights that leave Siena for Palermo onSun, Jun 21, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sun, Jun 21 the direct flights cover the 603 km distance in an average of 1 h 20 m but if you time it right, some flights will get you there in just 1 h 20 m .
On Sun, Jun 21 the longest flights will take 1 h 20 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Omio recommends booking the bus as it is the most popular option from Siena to Palermo among Omio's users. If you are prioritising price take the flight with prices starting from $21. For those with little time consider booking a flight which can get you there in 1h 22m. The ticket price range depends on the travel mode: a flight costs an average of $21, and a train costs an average of $95.
Distance: 374 miles (603 km)
| Flight | Most popular Bus | Ferry | Train | Driving |
|---|---|---|---|---|
$48 Average price Cheapest | $68 Average price | $60 Average price | $160 Average price | $82 Average price (fuel + tolls) |
4h 22m Average total duration Fastest 1h 22m Onboard + 3h 0m Additional time* | 16h 47m Average total duration 16h 17m Onboard + 30m Additional time* | 20h 30m Average total duration 19h 30m Onboard + 1h 0m Additional time* | 16h 37m Average total duration 16h 7m Onboard + 30m Additional time* | 11h 30m Average total duration (door-to-door) |
![]() Most popular airline | ![]() Most popular bus company | ![]() Most popular ferry company | ![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Siena to Palermo:
A flight is $12 (€10) less than a ferry for this route with tickets for a ferry from Siena to Palermo costing on average $60 (€49).
A flight is $19 (€16) less than a bus for this route with tickets for a bus from Siena to Palermo costing on average $68 (€55).
A flight is $112 (€91) less than a train for this route with tickets for a train from Siena to Palermo costing on average $160 (€131).
Other travel options to Palermo take longer:
Train takes on average 16h 7m.
Bus takes on average 16h 17m.
Ferry takes on average 19h 30m.
The table below shows live departures for Siena to Palermo flights for today, Saturday, June 20. You can also manually refresh the results below to see updated flight journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus+ AZ1789 | 10:35 AM Siena, P.za Gramsc | 11h55 | 10:30 PM Palermo Airport | 1 transfer | |
FlixBus+ AZ1769 | 10:35 AM Siena, P.za Gramsc | 10h30 | 9:05 PM Palermo Airport | 1 transfer | |
FlixBus+ XZ2717 | 10:35 AM Siena, P.za Gramsc | 12h10 | 10:45 PM Palermo Airport | 1 transfer | |
FlixBus+ XZ2717 | 10:45 AM Siena, Stazione FS (Piazzale Carlo Rosselli) | 12h00 | 10:45 PM Palermo Airport | 1 transfer | |
FlixBus+ AZ1769 | 10:55 AM Siena, Siena/Viale Pietro Toselli | 10h10 | 9:05 PM Palermo Airport | 1 transfer | |
FlixBus+ XZ2717 | 10:55 AM Siena, Siena/Viale Pietro Toselli | 11h50 | 10:45 PM Palermo Airport | 1 transfer | |
FR 3787 | 5:30 PM Perugia San Egidio Airport | 1h15 | 6:45 PM Palermo Airport | 0 transfersDirect | |
FR 8486 | 8:20 PM Pisa International Airport | 1h20 | 9:40 PM Palermo Airport | 0 transfersDirect | |
| Sunday, June 21 | |||||
![]() | 6:30 AM Siena | 1h20 | 7:50 AM Palermo | 0 transfersDirect | |
This is the last flight of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, flight, and ferry prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Discover the best of Palermo — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Palermo trip today.
Major art museum in a Gothic-Catalan palace, known for Sicilian medieval and Renaissance masterpieces including works by Antonello da Messina.
One of Sicily's most important archaeological museums, with Punic, Greek and Roman collections and notable sculpture fragments.
Historic noble residence preserved with original furnishings, offering a vivid look at aristocratic life in Palermo.
Energetic historic district centered on Palermo's most famous street market, full of everyday local life and vivid street scenes.
Striking central square framed by historic buildings and the famous fountain, a key stop in the old town.
One of Palermo's main historic streets, largely pedestrianized and lined with landmarks, shops and lively urban scenes.
Fried rice balls stuffed with ragù, mozzarella, or butter and ham. Palermo is famous for its round arancine and strong street-food tradition.
A classic Palermo street sandwich made with veal spleen and lung, often topped with caciocavallo or ricotta. It is one of the city's most iconic local bites.
Chickpea fritters, usually served in a sesame bread roll. They are a beloved Palermo snack and a staple of the city's historic friggitorie.
Well-regarded restaurant near the historic center serving refined Sicilian cuisine with local ingredients in an elegant but relaxed atmosphere.
Popular central spot for approachable Sicilian cooking, including pasta and regional classics, with a casual and lively atmosphere.
Established seafood-focused trattoria appreciated for traditional Palermo and Sicilian dishes in a classic local dining room.
Moderate by Italian standards: street food is cheap, while central hotels and tourist restaurants cost more.
Service is often included or minimal. Rounding up or leaving EUR 1-2 at cafes is common; about 5-10% for very good restaurant service. Taxis are usually rounded up.
Official public transport app
Palermo Airport -> Palermo Centrale
Find answers to the most common questions about traveling from Siena to Palermo by flight. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest flight, the cheapest option, or tips for making the most of your visit at Palermo, this guide helps you travel smarter and with confidence.

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