- Must visit
Antonino Salinas Regional Archaeological Museum
Palermo’s top museum displays Sicilian archaeology, including the famous Punic Stone and Selinunte finds, in a former convent complex.
Flights from Siena to Palermo depart on average 19 times per day, taking around 1h 22m. Cheap flight tickets for this journey start at $21 if you book in advance.
There are 3 flights per day. The earliest flight runs at 05:30, the last at 23:55. The fastest flight covers the 374 miles (603 km) distance in 1h 15m. January is the cheapest month to fly.
Distance 374 miles (603 km) |
Average flight duration 1h 22m |
Cheapest ticket price $21 |
Flights per day 19 |
Direct flights 3 |
Fastest flight 1h 15m |
First flight 5:30 AM |
Last flight 11:55 PM |
Cheapest Month Jan |
Cheapest Day Sat |
High Season Apr - Jun |
Low Season Jan - Mar |
Busiest Day Wed |
Least Busy Day Wed |
Best time to book 42 days |
Cheapest price
$40
Average price
$57
Fastest journey
1 h 20 m
Average duration
1 h 20 m
Flights per day
2
Distance
603 km
The best way to find a cheap flight ticket from Siena to Palermo is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Siena to Palermo will cost around $57 if you buy it on the day, but the cheapest tickets can be found for only $40.
Of the 2 flights that leave Siena for Palermo onWed, Aug 05, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Wed, Aug 05 the direct flights cover the 603 km distance in an average of 1 h 20 m but if you time it right, some flights will get you there in just 1 h 20 m .
On Wed, Aug 05 the longest flights will take 1 h 20 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.




Omio recommends booking the bus as it is the most popular option from Siena to Palermo among Omio's users. If you are prioritising price take the flight with prices starting from $21. For those with little time consider booking a flight which can get you there in 1h 22m. The ticket price range depends on the travel mode: a flight costs an average of $21, and a train costs an average of $95.
Distance: 374 miles (603 km)
| Flight | Most popular Bus | Ferry | Train | Driving |
|---|---|---|---|---|
$48 Average price Cheapest | $68 Average price | $60 Average price | $160 Average price | $82 Average price (fuel + tolls) |
4h 22m Average total duration Fastest 1h 22m Onboard + 3h 0m Additional time* | 16h 47m Average total duration 16h 17m Onboard + 30m Additional time* | 20h 30m Average total duration 19h 30m Onboard + 1h 0m Additional time* | 16h 37m Average total duration 16h 7m Onboard + 30m Additional time* | 11h 30m Average total duration (door-to-door) |
![]() Most popular airline | ![]() Most popular bus company | ![]() Most popular ferry company | ![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Siena to Palermo:
A flight is $12 less than a ferry for this route with tickets for a ferry from Siena to Palermo costing on average $60.
A flight is $20 less than a bus for this route with tickets for a bus from Siena to Palermo costing on average $68.
A flight is $112 less than a train for this route with tickets for a train from Siena to Palermo costing on average $160.
Other travel options to Palermo take longer:
Train takes on average 16h 7m.
Bus takes on average 16h 17m.
Ferry takes on average 19h 30m.
The table below shows live departures for Siena to Palermo flights for today, Tuesday, August 4. You can also manually refresh the results below to see updated flight journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus+ AZ1769 | 10:45 AM Siena, Stazione FS (Piazzale Carlo Rosselli) | 10h20 | 9:05 PM Palermo Airport | 1 transfer | |
FlixBus+ AZ1789 | 10:45 AM Siena, Stazione FS (Piazzale Carlo Rosselli) | 11h45 | 10:30 PM Palermo Airport | 1 transfer | |
FlixBus+ XZ2717 | 10:45 AM Siena, Stazione FS (Piazzale Carlo Rosselli) | 12h00 | 10:45 PM Palermo Airport | 1 transfer | |
FR 8450 | 11:20 AM Pisa International Airport | 1h20 | 12:40 PM Palermo Airport | 0 transfersDirect | |
FR 3787 | 7:45 PM Perugia San Egidio Airport | 1h15 | 9:00 PM Palermo Airport | 0 transfersDirect | |
FR 8486 | 8:35 PM Pisa International Airport | 1h20 | 9:55 PM Palermo Airport | 0 transfersDirect | |
| Wednesday, August 5 | |||||
![]() | 4:35 AM Siena | 1h20 | 5:55 AM Palermo | 0 transfersDirect | |
This is the last flight of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, flight, and ferry prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Discover the best of Palermo — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Palermo trip today.
Palermo’s top museum displays Sicilian archaeology, including the famous Punic Stone and Selinunte finds, in a former convent complex.
Historic rooms and vivid majolica floors showcase aristocratic Palermo. Visit for decorative arts, period interiors and city history.
Housed in the grand Steri Palace, this museum presents the Sicilian Inquisition’s story through cells, graffiti and historical documents.
Palermo’s elegant main boulevard links major monuments, shops and theaters. Ideal for first walks and observing the city’s layered architecture.
This historic street cuts across the old center and hosts markets, churches and daily life. A lively route for exploring local Palermo.
A bustling old quarter famous for layered street life, churches and market culture. Best explored on foot for atmosphere and urban history.
Crisp fried rice ball stuffed with ragù, peas and caciocavallo. A Sicilian street food icon widely loved in Palermo.
Soft sesame-topped bun filled with spleen and lung, often with caciocavallo or ricotta. A classic Palermo street food with deep local roots.
Pasta with sardines, wild fennel, pine nuts and raisins. Its sweet-savory flavor reflects Palermo's Arab-Norman culinary heritage.
Refined Michelin-starred restaurant known for creative Sicilian tasting menus in an elegant, intimate setting.
Historic seafood restaurant near the port, praised for fresh catch, raw dishes and classic Palermo fish recipes.
Legendary no-frills street-food stop celebrated for pane con la milza and authentic local sandwiches loved by residents.
Moderate for Italy. Street food and local meals are affordable, while hotels in peak season cost more. Public transport is cheap, keeping overall tourist costs reasonable.
Service is often included or modest. Round up or leave 5-10% for great restaurant service. Taxis are usually rounded up. Small change is fine in cafes.
Official public transport app
Palermo Airport, Palermo -> Palermo Centrale, Palermo
Find answers to the most common questions about traveling from Siena to Palermo by flight. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest flight, the cheapest option, or tips for making the most of your visit at Palermo, this guide helps you travel smarter and with confidence.

Most Siena to Palermo flights use the Florence Peretola Airport to Palermo Airport airport pair. Use this guide to compare Siena and Palermo airports on this route, check city-centre transport, alongside checking practicalities like airport facilities and services.
Palermo Airport is 2 km from Palermo city centre. Public transport options include:
Palermo Airport has practical services for this route, including Wifi, Shopping, Parking, ATM, Taxis, Accessibility, WC, Shower, Lounge, and Lost and Found Office.
Free Wi-Fi available throughout the airport. ATMs are located in the arrivals and departures areas.
Lost and found is available at the station.
Available at Palermo Airport: Parking, Taxis, WC.
Accessibility facilities are available at Palermo Airport: Elevators, ramps.
Here are some other resources that might have the information you need