The cheapest and fastest trains from Siena to Palermo
Cheapest price
$139
Average price
$159
Fastest journey
14 h 43 m
Average duration
16 h 19 m
Trains per day
3
Distance
603 km
The best way to find a cheap train ticket from Siena to Palermo is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Siena to Palermo will cost around $159 if you buy it on the day, but the cheapest tickets can be found for only $139.
It's difficult to get from Siena to Palermo without transferring at least 2 times.
Regionale 18238+
FRECCIAROSSA 1000 9563+
InterCityNotte 19597:18 PM18h25Siena station1:43 PMPalermo Centrale$1391One-way2 transfers
Regionale 18234+
FRECCIAROSSA 1000 9555+
InterCityNotte 19555:18 PM15h50Siena station9:08 AMPalermo Centrale$1551One-way2 transfers
Regionale 18214+
FRECCIAROSSA 9519+
Intercity 7278:18 AM14h43Siena station11:01 PMPalermo Centrale$1831One-way2 transfers
Regionale 18214+
FRECCIAROSSA 9519+
Intercity 7278:18 AM14h43Siena station11:01 PMPalermo Centrale$1831One-way2 transfers
Regionale 18234+
FRECCIAROSSA 1000 9555+
InterCityNotte 19555:18 PM15h50Siena station9:08 AMPalermo Centrale$1551One-way2 transfers
Regionale 18238+
FRECCIAROSSA 1000 9563+
InterCityNotte 19597:18 PM18h25Siena station1:43 PMPalermo Centrale$1391One-way2 transfers
Travel Information
Compare bus, train, flight, and ferry for Siena to Palermo
Omio recommends booking the bus as it is the most popular option from Siena to Palermo among Omio's users. If you are prioritising price take the ferry with prices starting from $50. For those with little time consider booking a flight which can get you there in 1h 23m. The ticket price range depends on the travel mode: a ferry costs an average of $50, and a train costs an average of $97.
Distance: 374 miles (603 km)
Compare train with
| Train | Most popular Bus | Flight | Ferry | Driving |
|---|---|---|---|---|
$154 Average price | $76 Average price | $129 Average price | $67 Average price Cheapest | $84 Average price (fuel + tolls) |
16h 37m Average total duration 16h 7m Onboard + 30m Additional time* | 16h 46m Average total duration 16h 16m Onboard + 30m Additional time* | 4h 23m Average total duration Fastest 1h 23m Onboard + 3h 0m Additional time* | 20h 30m Average total duration 19h 30m Onboard + 1h 0m Additional time* | 11h 30m Average total duration (door-to-door) |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular ferry company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Siena to Palermo:
A ferry is $9 (€7) less than a bus for this route with tickets for a bus from Siena to Palermo costing on average $76 (€60).
A ferry is $62 (€50) less than a flight for this route with tickets for a flight from Siena to Palermo costing on average $129 (€103).
A ferry is $87 (€69) less than a train for this route with tickets for a train from Siena to Palermo costing on average $154 (€122).
Other travel options to Palermo take longer:
Train takes on average 16h 7m.
Bus takes on average 16h 16m.
Ferry takes on average 19h 30m.
Tickets start at around $154 (€122) compared to roughly $84 (€67) in fuel and tolls — a saving of about $-69.31 (€-55.28). The journey takes 16h 7m versus 11h 30m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
Live departures
Siena to Palermo train times
The table below shows live departures for Siena to Palermo trains for today, Thursday, May 7. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 12:32 PM Siena | 19h34 | 8:06 AM Palermo | 0 transfersDirect | |
![]() | 4:43 PM Siena | 19h29 | 12:12 PM Palermo | 0 transfersDirect | |
![]() | 5:18 PM Siena | 18h21 | 11:39 AM Palermo | 0 transfersDirect | |
![]() | 6:18 PM Siena | 17h21 | 11:39 AM Palermo | 0 transfersDirect | |
| Friday, May 8 | |||||
![]() | 7:18 AM Siena | 15h17 | 10:35 PM Palermo | 0 transfersDirect | |
Find all the dates and times for this journey
Compare prices and tickets Siena to Palermo by bus, train, flight, or ferry
Compare bus, train, flight, and ferry prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
May 08
May 09
May 10
May 11
May 12
May 13
May 14
Journey information
Overview: Train from Siena to Palermo
Trains from Siena to Palermo run on average 2 times per day, taking around 16h 7m. Cheap train tickets for this journey start at $97 (€77) but you can travel from only $22 (€17) by flight.
The earliest train runs at 00:03, the last at 21:10. The fastest train covers the 374 miles (603 km) distance in 14h 37m.
Distance 374 miles (603 km) |
Average train duration 16h 7m |
Cheapest ticket price $97 (€77) |
Trains per day 2 |
Fastest train 14h 37m |
First train 12:03 AM |
Last train 9:10 PM |
Cheapest Month Sep |
Cheapest Day Sun |
High Season Apr - Jun |
Low Season Jan - Mar |
Busiest Day Mon |
Least Busy Day Mon |
Best time to book 70 days |
Train companies: Intercity Notte, Regionale from Siena to Palermo trainsIntercity Notte, Regionale trains will get you between Siena and Palermo from $22 (€17). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Intercity Notte
Regionale
FAQs: Trains from Siena to Palermo
Find answers to the most common questions about traveling from Siena to Palermo by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Palermo, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Siena to Palermo
- 6:00 AM - 8:00 PM Monday - Sunday
- Free
- Parking is available near the station, open 24/7.
- Ristorante Il Vinaio
- Osteria Le Logge
- Outside the main entrance.
- Elevators, ramps.
- €1
- Hotel Italia
- NH Siena
- Hotel Minerva
- Located near the main entrance
- Located near the main entrance
- Free
- The station has a single-level layout with platforms accessible from the main hall.
- Bus: Several local and regional lines available
- Taxi: Available outside the station
Most popular train connections from Siena
More options for your journey from Siena to Palermo
Here are some other resources that might have the information you need



