- Must visit
Antonino Salinas Regional Archaeological Museum
Palermo’s top museum displays Sicilian archaeology, including the famous Punic Stone and Selinunte finds, in a former convent complex.
Cheapest price
$142
Average price
$169
Fastest journey
14 h 40 m
Average duration
15 h 24 m
Trains per day
3
Distance
603 km
The best way to find a cheap train ticket from Siena to Palermo is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Siena to Palermo will cost around $169 if you buy it on the day, but the cheapest tickets can be found for only $142.
Of the 3 trains that leave Siena for Palermo on Sat, Aug 08, 3 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sat, Aug 08 the direct trains cover the 603 km distance in an average of 15 h 24 m but if you time it right, some trains will get you there in just 14 h 40 m .
On Sat, Aug 08 the slowest trains will take 16 h 50 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.






Omio recommends booking the bus as it is the most popular option from Siena to Palermo among Omio's users. If you are prioritising price take the flight with prices starting from $21. For those with little time consider booking a flight which can get you there in 1h 22m. The ticket price range depends on the travel mode: a flight costs an average of $21, and a train costs an average of $96.
Distance: 374 miles (603 km)
| Train | Most popular Bus | Flight | Ferry | Driving |
|---|---|---|---|---|
$161 Average price | $68 Average price | $48 Average price Cheapest | $60 Average price | $82 Average price (fuel + tolls) |
16h 37m Average total duration 16h 7m Onboard + 30m Additional time* | 16h 47m Average total duration 16h 17m Onboard + 30m Additional time* | 4h 22m Average total duration Fastest 1h 22m Onboard + 3h 0m Additional time* | 20h 30m Average total duration 19h 30m Onboard + 1h 0m Additional time* | 11h 30m Average total duration (door-to-door) |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular ferry company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Siena to Palermo:
A flight is $12 (€10) less than a ferry for this route with tickets for a ferry from Siena to Palermo costing on average $60 (€49).
A flight is $20 (€16) less than a bus for this route with tickets for a bus from Siena to Palermo costing on average $68 (€55).
A flight is $112 (€91) less than a train for this route with tickets for a train from Siena to Palermo costing on average $161 (€131).
Other travel options to Palermo take longer:
Train takes on average 16h 7m.
Bus takes on average 16h 17m.
Ferry takes on average 19h 30m.
Tickets start at around $161 (€131) compared to roughly $82 (€67) in fuel and tolls — a saving of about $-78.20 (€-63.70). The journey takes 16h 7m versus 11h 30m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
The table below shows live departures for Siena to Palermo trains for tomorrow, Saturday, August 8. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 6:18 AM Siena | 14h40 | 8:58 PM Palermo | 0 transfersDirect | |
![]() | 7:18 AM Siena | 14h43 | 10:01 PM Palermo | 0 transfersDirect | |
![]() | 2:18 PM Siena | 16h50 | 7:08 AM Palermo | 0 transfersDirect | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, flight, and ferry prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Trains from Siena to Palermo run on average 3 times per day, taking around 16h 7m. Cheap train tickets for this journey start at $96 (€78) but you can travel from only $21 (€17) by flight.
The earliest train runs at 00:03, the last at 21:10. The fastest train covers the 374 miles (603 km) distance in 14h 40m.
Distance 374 miles (603 km) |
Average train duration 16h 7m |
Cheapest ticket price $96 (€78) |
Trains per day 3 |
Fastest train 14h 40m |
First train 12:03 AM |
Last train 9:10 PM |
Cheapest Month Sep |
Cheapest Day Sun |
High Season Apr - Jun |
Low Season Jan - Mar |
Busiest Day Wed |
Least Busy Day Wed |
Best time to book 70 days |
Discover the best of Palermo — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Palermo trip today.
Palermo’s top museum displays Sicilian archaeology, including the famous Punic Stone and Selinunte finds, in a former convent complex.
Historic rooms and vivid majolica floors showcase aristocratic Palermo. Visit for decorative arts, period interiors and city history.
Housed in the grand Steri Palace, this museum presents the Sicilian Inquisition’s story through cells, graffiti and historical documents.
Palermo’s elegant main boulevard links major monuments, shops and theaters. Ideal for first walks and observing the city’s layered architecture.
This historic street cuts across the old center and hosts markets, churches and daily life. A lively route for exploring local Palermo.
A bustling old quarter famous for layered street life, churches and market culture. Best explored on foot for atmosphere and urban history.
Crisp fried rice ball stuffed with ragù, peas and caciocavallo. A Sicilian street food icon widely loved in Palermo.
Soft sesame-topped bun filled with spleen and lung, often with caciocavallo or ricotta. A classic Palermo street food with deep local roots.
Pasta with sardines, wild fennel, pine nuts and raisins. Its sweet-savory flavor reflects Palermo's Arab-Norman culinary heritage.
Refined Michelin-starred restaurant known for creative Sicilian tasting menus in an elegant, intimate setting.
Historic seafood restaurant near the port, praised for fresh catch, raw dishes and classic Palermo fish recipes.
Legendary no-frills street-food stop celebrated for pane con la milza and authentic local sandwiches loved by residents.
Moderate for Italy. Street food and local meals are affordable, while hotels in peak season cost more. Public transport is cheap, keeping overall tourist costs reasonable.
Service is often included or modest. Round up or leave 5-10% for great restaurant service. Taxis are usually rounded up. Small change is fine in cafes.
Official public transport app
Palermo Centrale -> Quattro Canti, Palermo
Find answers to the most common questions about traveling from Siena to Palermo by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Palermo, this guide helps you travel smarter and with confidence.

Most Siena to Palermo trains use the Siena to Palermo Centrale station pair. Use this guide to compare Siena and Palermo train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Siena is 1 km from Siena city centre. Public transport options include:
Siena has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Information Desk, and Luggage Carts.
Food options include: Ristorante Il Vinaio, Osteria Le Logge
Free. ATMs are available in the train station.
Ticket office support is available at Siena. Information desks are located near the main entrance.
Luggage storage is available at Siena. Lost and found is available at the station.
Available at Siena: Parking, Taxis, WC.
Available at Siena: Bike Parking, Bike Rental.
Accessibility facilities are available at Siena: Elevators, ramps.
Nearby hotels include Hotel Italia, NH Siena, Hotel Minerva.
Here are some other resources that might have the information you need