- Must visit
Vatican Museums
World-famous papal museums with the Sistine Chapel, Raphael Rooms, and major classical collections.



Cheapest price
$13
Average price
$21
Fastest journey
2h 30m
Average duration
3h 3m
Buses per day
3
Distance
0 km
Omio recommends booking the bus as it is the most popular option from Sant'Agnello to Rome among Omio's users. If you are prioritising price take the bus with prices starting from $6. For those with little time consider booking a flight which can get you there in 1h 12m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.2kg. The ticket price range depends on the travel mode: a bus costs an average of $6, and a flight costs an average of $76.
Distance: 132 miles (213 km)
Most popular Bus | Train | Flight | Driving |
|---|---|---|---|
$24 Average price Cheapest | $60 Average price | $141 Average price | $75 Average price (fuel + tolls) |
3h 48m Average total duration 3h 18m Onboard + 30m Additional time* | 2h 18m Average total duration 1h 48m Onboard + 30m Additional time* | 4h 12m Average total duration Fastest 1h 12m Onboard + 3h 0m Additional time* | 3h 5m Average total duration (door-to-door) |
0.2 - 0.5kg CO2 emissions | 0.1 - 0.2kg CO2 emissions Lowest | 0.6 - 1.3kg CO2 emissions | - CO2 emissions |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Sant'Agnello to Rome:
A bus is $36 (€30) less than a train for this route with tickets for a train from Sant'Agnello to Rome costing on average $60 (€49).
A bus is $117 (€96) less than a flight for this route with tickets for a flight from Sant'Agnello to Rome costing on average $141 (€116).
Other travel options to Rome take longer:
Train takes on average 1h 48m.
Bus takes on average 3h 18m.
Tickets start at around $24 (€20) compared to roughly $75 (€62) in fuel and tolls — a saving of about $51 (€42). The journey takes 3h 18m versus 3h 5m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by FlixBus, BlaBlaCar.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Marozzi | Departure Time 04:08AM | Arrival Time 07:45AM | Duration 3h37 | Departure days Tue | Cheapest price $28 |
Operator FlixBus | Departure Time 04:20AM | Arrival Time 10:30AM | Duration 6h10 | Departure days Tue, Wed, Thu | Cheapest price $22 |
Operator Marozzi | Departure Time 05:08AM | Arrival Time 08:45AM | Duration 3h37 | Departure days Tue | Cheapest price $29 |
Operator FlixBus | Departure Time 05:20AM | Arrival Time 11:30AM | Duration 6h10 | Departure days Thu | Cheapest price $19 |
Operator Marozzi | Departure Time 06:08AM | Arrival Time 09:45AM | Duration 3h37 | Departure days Mon, Fri | Cheapest price $28 |
Operator FlixBus | Departure Time 06:20AM | Arrival Time 10:40AM | Duration 4h20 | Departure days Mon, Fri, Sat | Cheapest price $22 |
Operator BlaBlaCar | Departure Time 06:30AM | Arrival Time 10:20AM | Duration 3h50 | Departure days Mon | Cheapest price $21 |
Operator BlaBlaCar | Departure Time 08:00AM | Arrival Time 11:20AM | Duration 3h20 | Departure days Sat | Cheapest price $21 |
Operator BlaBlaCar | Departure Time 09:00AM | Arrival Time 11:40AM | Duration 2h40 | Departure days Mon | Cheapest price $19 |
Operator BlaBlaCar | Departure Time 10:30AM | Arrival Time 01:20PM | Duration 2h50 | Departure days Sat | Cheapest price $23 |
Operator BlaBlaCar | Departure Time 10:40AM | Arrival Time 01:00PM | Duration 2h20 | Departure days Fri | Cheapest price $23 |
Operator BlaBlaCar Bus | Departure Time 11:30AM | Arrival Time 02:15PM | Duration 2h45 | Departure days Wed | Cheapest price $9 |
Operator Marozzi | Departure Time 02:10PM | Arrival Time 06:00PM | Duration 3h50 | Departure days Sun | Cheapest price $29 |
Operator Italo | Departure Time 02:45PM | Arrival Time 06:30PM | Duration 3h45 | Departure days Mon, Sat | Cheapest price $67 |
Operator BlaBlaCar | Departure Time 03:00PM | Arrival Time 05:30PM | Duration 2h30 | Departure days Fri | Cheapest price $16 |
Operator BlaBlaCar | Departure Time 03:20PM | Arrival Time 05:40PM | Duration 2h20 | Departure days Fri, Sat | Cheapest price $18 |
Operator BlaBlaCar | Departure Time 03:40PM | Arrival Time 06:10PM | Duration 2h30 | Departure days Sat | Cheapest price $23 |
Operator Marozzi | Departure Time 04:10PM | Arrival Time 08:00PM | Duration 3h50 | Departure days Mon, Fri, Sat | Cheapest price $28 |
Operator BlaBlaCar | Departure Time 05:00PM | Arrival Time 07:50PM | Duration 2h50 | Departure days Mon | Cheapest price $21 |
Operator BlaBlaCar | Departure Time 06:00PM | Arrival Time 08:30PM | Duration 2h30 | Departure days Fri | Cheapest price $13 |
Operator BlaBlaCar | Departure Time 06:30PM | Arrival Time 08:40PM | Duration 2h10 | Departure days Mon | Cheapest price $19 |
Operator Italo | Departure Time 07:45PM | Arrival Time 11:30PM | Duration 3h45 | Departure days Sat | Cheapest price $80 |
Operator BlaBlaCar | Departure Time 08:00PM | Arrival Time 10:20PM | Duration 2h20 | Departure days Mon | Cheapest price $21 |
Operator Itabus | Departure Time 08:15PM | Arrival Time 10:55PM | Duration 2h40 | Departure days Wed | Cheapest price $6 |
Operator BlaBlaCar | Departure Time 09:30PM | Arrival Time 12:20AM | Duration 2h50 | Departure days Fri | Cheapest price $23 |
Operator BlaBlaCar | Departure Time 10:40PM | Arrival Time 01:10AM | Duration 2h30 | Departure days Sat | Cheapest price $18 |
The table below shows live departures for Sant'Agnello to Rome buses for today, Friday, July 17. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
23 - 23R | 4:10 PM Sant'Agnello, Corso Italia (Bar Siesta) | 3h50 | 8:00 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
| Saturday, July 18 | |||||
FlixBus | 6:20 AM Sant'Agnello, Corso Italia / Via Don Minzoni (Town Hall) | 4h20 | 10:40 AM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus · FlixBus | 6:20 AM Sant'Agnello, Corso Italia / Via Don Minzoni (Town Hall) | 5h30 | 11:50 AM Roma, Autostazione (Metro Anagnina) | 1 transfer | |
Itabus | 1002 · 9954 | 2:45 PM Sant'Agnello | 3h45 | 6:30 PM Rome Termini | 1 transfer | |
Itabus | 1002 · 9954 | 2:45 PM Sant'Agnello | 4h03 | 6:48 PM Rome Tiburtina | 1 transfer | |
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Sant'Agnello to Rome run on average 7 times per day, taking around 3h 18m. Cheap bus tickets for this journey start at $6 (€5) if you book in advance.
There are 6 buses per day. The earliest bus runs at 03:20, the last at 23:40. The fastest bus covers the 132 miles (213 km) distance in 2h 40m.
Distance 132 miles (213 km) |
Average bus duration 3h 18m |
Cheapest ticket price $6 (€5) |
Buses per day 7 |
Direct buses 6 |
Fastest bus 2h 40m |
First bus 3:20 AM |
Last bus 11:40 PM |
Cheapest Month Mar |
Cheapest Day Mon |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Wed |
Least Busy Day Fri |
Best time to book 35 days |
Discover the best of Rome — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Rome trip today.
World-famous papal museums with the Sistine Chapel, Raphael Rooms, and major classical collections.
Outstanding ancient sculpture and mosaic museum housed in the Palazzo dei Conservatori and Palazzo Nuovo.
Celebrated villa museum with Bernini sculptures, Caravaggio paintings, and refined garden setting.
Elegant Baroque square with Bernini's fountains, lively atmosphere, and superb people-watching.
Historic square and gathering place at the Spanish Steps, ideal for classic city views and strolls.
Charming cobbled neighborhood filled with ivy-clad lanes, churches, nightlife, and local character.
Classic Roman pasta with guanciale, egg yolk, Pecorino Romano, and black pepper. A city icon known for rich flavor without cream.
Roman pasta with guanciale, tomato, and Pecorino Romano. A traditional Lazio staple tied to shepherd cooking and bold savory flavor.
Pasta with guanciale, Pecorino Romano, and black pepper. Considered one of Rome's oldest pasta dishes and prized for its simplicity.
Three-Michelin-star dining by Niko Romito at Bulgari Hotel Roma, offering refined Italian tasting menus in an elegant setting.
Historic trattoria in Testaccio known for classic Roman pasta and quinto quarto dishes in a lively, traditional setting.
Popular casual spot famed for Roman-style pizzas and fried starters. Bustling atmosphere and a long-standing local reputation.
Moderate for Europe: stays in central Rome are pricey, but transit is cheap and meals range from affordable pizza to costly tourist-area dining.
Service may be included via coperto or servizio. Round up or leave 5-10% at restaurants if service is good; round up in taxis; small change is fine at cafés.
Official public transport app
Via Marsala, Rome -> Piazza Barberini, Rome
Find answers to the most common questions about traveling from Sant'Agnello to Rome by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Rome, this guide helps you travel smarter and with confidence.

Most Sant'Agnello to Rome buses use the Napoli, Autostazione Metropark to Roma, Autostazione Tiburtina station pair, with some services arriving at Roma, Autostazione (Metro Anagnina). Use this guide to compare Sant'Agnello and Rome bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Roma, Via Marsala / Viale Enrico De Nicola is 1 km from Rome city centre. Public transport options include:
Roma, Via Marsala / Viale Enrico De Nicola has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafeteria della Stazione (in the station), Trattoria Marsala (0.2 km), Pizzeria Enrico (0.5 km).
Free Wi-Fi. ATMs are located near the main entrance of the station.
Ticket office support is available at Roma, Via Marsala / Viale Enrico De Nicola.
Available at Roma, Via Marsala / Viale Enrico De Nicola: Parking, Taxis, WC.
Accessibility facilities are available at Roma, Via Marsala / Viale Enrico De Nicola: Elevators, ramps.
Here are some other resources that might have the information you need