The cheapest and fastest buses from Santa Margherita Ligure to Rome
Cheapest price
$21
Average price
$51
Fastest journey
7 h 25 m
Average duration
8 h 20 m
Buses per day
3
Distance
380 km
The best way to find a cheap bus ticket from Santa Margherita Ligure to Rome is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Santa Margherita Ligure to Rome will cost around $51 if you buy it on the day, but the cheapest tickets can be found for only $21.
Of the 3 buses that leave Santa Margherita Ligure for Rome on Mon, Mar 23, 3 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Mon, Mar 23 the direct buses cover the 380 km distance in an average of 8 h 20 m but if you time it right, some buses will get you there in just 7 h 25 m .
On Mon, Mar 23 the slowest buses will take 9 h 25 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.






Travel Information
Compare train, bus, and flight for Santa Margherita Ligure to Rome
Omio recommends booking the train as it is the most popular option from Santa Margherita Ligure to Rome among Omio's users. If you are prioritising price take the train with prices starting from $27. For those with little time consider booking a flight which can get you there in 1h 21m. The ticket price range depends on the travel mode: a train costs an average of $27, and a flight costs an average of $56.
Distance: 236 miles (380 km)
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
$45 Average price | $41 Average price Cheapest | $68 Average price |
8h 0m Average total duration 7h 30m Onboard + 30m Additional time* | 5h 39m Average total duration 5h 9m Onboard + 30m Additional time* | 4h 21m Average total duration Fastest 1h 21m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
Santa Margherita Ligure to Rome Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator BlaBlaCar | Departure Time 08:20AM | Arrival Time 02:20PM | Duration 6h00 | Departure days Sun | Cheapest price $42 |
Operator BlaBlaCar | Departure Time 11:30AM | Arrival Time 04:20PM | Duration 4h50 | Departure days Sun | Cheapest price $47 |
Operator BlaBlaCar | Departure Time 12:10PM | Arrival Time 06:10PM | Duration 6h00 | Departure days Sun | Cheapest price $64 |
Operator BlaBlaCar | Departure Time 12:30PM | Arrival Time 05:30PM | Duration 5h00 | Departure days Sun | Cheapest price $54 |
Operator Busitalia | Departure Time 05:45PM | Arrival Time 11:59PM | Duration 6h14 | Departure days Sun | Cheapest price $56 |
Operator Marino Autolinee | Departure Time 07:05PM | Arrival Time 04:30AM | Duration 9h25 | Departure days Sun | Cheapest price $85 |
Live departures
Santa Margherita Ligure to Rome bus times
The table below shows live departures for Santa Margherita Ligure to Rome buses for tomorrow, Sunday, March 22. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 1:25 PM Santa Margherita Ligure | 8h10 | 9:35 PM Rome | 0 transfersDirect | |
![]() | 6:05 PM Santa Margherita Ligure | 9h25 | 3:30 AM Rome | 0 transfersDirect | |
![]() | 10:25 PM Santa Margherita Ligure | 7h25 | 5:50 AM Rome | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Santa Margherita Ligure to Rome by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Mar 23
Mar 24
Mar 25
Mar 26
Mar 27
Mar 28
Mar 29
Why should you book Santa Margherita Ligure to Rome buses with Omio?
Why book with Omio vs Itabus?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Itabus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Santa Margherita Ligure to Rome.
Why book with Omio over Checkmybus or Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Santa Margherita Ligure to Rome.
Journey information
Overview: Bus from Santa Margherita Ligure to Rome
Buses from Santa Margherita Ligure to Rome run on average 14 times per day, taking around 7h 30m. Cheap bus tickets for this journey start at $17 (€14) if you book in advance.
There are 12 buses per day. The earliest bus runs at 00:02, the last at 23:55. The fastest bus covers the 236 miles (380 km) distance in 6h 0m.
Distance 236 miles (380 km) |
Average bus duration 7h 30m |
Cheapest ticket price $17 (€14) |
Buses per day 14 |
Direct buses 12 |
Fastest bus 6h 0m |
First bus 00:02 |
Last bus 23:55 |
Cheapest month Nov |
Cheapest day Sat |
High season Jul - Sep |
Low season Jan - Mar |
Busiest day Wed |
Least busy day Sat |
Best day to book ahead 14 days |
Bus providers: Itabus from Santa Margherita Ligure to RomeYou can travel by bus between Santa Margherita Ligure to Rome with Itabus for as low as $17 (€14). When you search for schedules and tickets, Omio will show you the best journey
Itabus
FAQs: Bus from Santa Margherita Ligure to Rome
Find answers to the most common questions about traveling from Santa Margherita Ligure to Rome by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Rome, this guide helps you travel smarter and with confidence.

- Itabus
- Assistance
- Dedicated seating areas
- Accessible restrooms.
- Colosseum, an ancient amphitheater known for its gladiatorial contests and iconic architecture
- Vatican Museums, a vast collection of art and historical artifacts including the Sistine Chapel
- Roman Forum, the ruins of ancient Rome's center for public life and government
- Pantheon, a well-preserved Roman temple with a striking dome and oculus
- Trevi Fountain, a famous Baroque fountain where visitors traditionally toss coins for good luck.
- Explore Trastevere, a charming neighborhood with narrow streets and vibrant nightlife
- Take a stroll through Villa Borghese, a beautiful park with museums and gardens
- Enjoy a gelato at Piazza Navona, a lively square with fountains and street artists
- Visit the Spanish Steps, a popular spot for people-watching and enjoying the view
- Discover the Catacombs, ancient underground burial sites with guided tours.
- Itabus
- You can cancel your ticket up to 24 hours before departure for a partial refund. Changes allowed for a fee.
- Itabus
- One carry-on bag up to 10kg and one checked bag up to 20kg.
- Itabus
- 5€ per additional bag.
- Itabus
- Small pets allowed in carriers
- larger pets must be leashed and muzzled.
popular bus stations
Popular bus stations from Santa Margherita Ligure to Rome
- 06:00-23:00
- Free Wi-Fi
- Ristorante Italiano (in the station)
- Fast Food Express (in the station)
- Caffè del Terminal (in the station).
- Available outside the arrivals terminal.
- Elevators, ramps
- Available in the station.
- Bus: 520, 720 Train: Leonardo Express
More options for your journey from Santa Margherita Ligure to Rome
Here are some other resources that might have the information you need
