- Must visit
Vatican Museums
One of the world’s greatest museum complexes, known for classical sculpture, Renaissance masterpieces, and the Sistine Chapel. Advance booking is strongly recommended due to very high demand.
Cheapest price
$31
Average price
$42
Fastest journey
6 h 5 m
Average duration
11 h 3 m
Buses per day
8
Distance
380 km
The best way to find a cheap bus ticket from Santa Margherita Ligure to Rome is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Santa Margherita Ligure to Rome will cost around $42 if you buy it on the day, but the cheapest tickets can be found for only $31.
Of the 8 buses that leave Santa Margherita Ligure for Rome on Mon, Jun 22, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Mon, Jun 22 the direct buses cover the 380 km distance in an average of 11 h 3 m but if you time it right, some buses will get you there in just 6 h 5 m .
On Mon, Jun 22 the slowest buses will take 13 h 30 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
1801
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
1801
061 · 055
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBusOmio recommends booking the train as it is the most popular option from Santa Margherita Ligure to Rome among Omio's users. If you are prioritising price take the train with prices starting from $26. For those with little time consider booking a train which can get you there in 5h 12m. The ticket price range depends on the travel mode: a train costs an average of $26, and a bus costs an average of $13.
Distance: 236 miles (380 km)
| Bus | Most popular Train | Driving |
|---|---|---|
$53 Average price | $40 Average price Cheapest | $131 Average price (fuel + tolls) |
8h 0m Average total duration 7h 30m Onboard + 30m Additional time* | 5h 42m Average total duration Fastest 5h 12m Onboard + 30m Additional time* | 5h 4m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Santa Margherita Ligure to Rome:
A train is $13 (€11) less than a bus for this route with tickets for a bus from Santa Margherita Ligure to Rome costing on average $53 (€44).
Other travel options to Rome take longer:
Bus takes on average 7h 30m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator BlaBlaCar | Departure Time 12:30AM | Arrival Time 06:10AM | Duration 5h40 | Departure days Sat | Cheapest price $58 |
Operator BlaBlaCar | Departure Time 02:20AM | Arrival Time 07:30AM | Duration 5h10 | Departure days Sun | Cheapest price $36 |
Operator BlaBlaCar | Departure Time 09:00AM | Arrival Time 01:50PM | Duration 4h50 | Departure days Sun | Cheapest price $50 |
Operator BlaBlaCar | Departure Time 09:50AM | Arrival Time 02:30PM | Duration 4h40 | Departure days Mon | Cheapest price $30 |
Operator Regionale | Departure Time 02:55PM | Arrival Time 06:00AM | Duration 15h05 | Departure days Sat | Cheapest price $39 |
Operator Regionale | Departure Time 03:14PM | Arrival Time 06:00AM | Duration 14h46 | Departure days Sat | Cheapest price $39 |
Operator Busitalia | Departure Time 03:45PM | Arrival Time 09:59PM | Duration 6h14 | Departure days Fri | Cheapest price $56 |
Operator Intercity | Departure Time 03:46PM | Arrival Time 06:00AM | Duration 14h14 | Departure days Sat | Cheapest price $43 |
Operator Regionale | Departure Time 03:55PM | Arrival Time 06:00AM | Duration 14h05 | Departure days Sat | Cheapest price $39 |
Operator FlixBus | Departure Time 04:05PM | Arrival Time 06:05AM | Duration 14h00 | Departure days Mon, Thu, Sun | Cheapest price $32 |
Operator Frecciabianca | Departure Time 04:06PM | Arrival Time 06:00AM | Duration 13h54 | Departure days Sat | Cheapest price $49 |
Operator Regionale | Departure Time 04:17PM | Arrival Time 06:00AM | Duration 13h43 | Departure days Sat | Cheapest price $39 |
Operator FlixBus | Departure Time 04:20PM | Arrival Time 06:05AM | Duration 13h45 | Departure days Mon, Thu, Sun | Cheapest price $34 |
Operator FlixBus | Departure Time 04:35PM | Arrival Time 06:05AM | Duration 13h30 | Departure days Mon, Thu, Sun | Cheapest price $34 |
Operator Busitalia | Departure Time 04:45PM | Arrival Time 10:59PM | Duration 6h14 | Departure days Fri | Cheapest price $49 |
Operator Regionale | Departure Time 04:46PM | Arrival Time 06:00AM | Duration 13h14 | Departure days Sat | Cheapest price $39 |
Operator Regionale | Departure Time 04:58PM | Arrival Time 06:00AM | Duration 13h02 | Departure days Sat | Cheapest price $39 |
Operator Intercity | Departure Time 05:46PM | Arrival Time 06:00AM | Duration 12h14 | Departure days Sat | Cheapest price $43 |
Operator Regionale | Departure Time 05:53PM | Arrival Time 06:00AM | Duration 12h07 | Departure days Sat | Cheapest price $39 |
Operator Regionale | Departure Time 06:03PM | Arrival Time 06:00AM | Duration 11h57 | Departure days Sat | Cheapest price $39 |
Operator Regionale | Departure Time 06:10PM | Arrival Time 06:00AM | Duration 11h50 | Departure days Sat | Cheapest price $39 |
Operator Regionale | Departure Time 06:46PM | Arrival Time 06:00AM | Duration 11h14 | Departure days Sat | Cheapest price $39 |
Operator Regionale | Departure Time 06:55PM | Arrival Time 06:00AM | Duration 11h05 | Departure days Sat | Cheapest price $39 |
Operator Marino Autolinee | Departure Time 07:05PM | Arrival Time 04:30AM | Duration 9h25 | Departure days Mon, Tue, Wed, Thu, Sun | Cheapest price $61 |
Operator Regionale | Departure Time 07:11PM | Arrival Time 06:00AM | Duration 10h49 | Departure days Sat | Cheapest price $39 |
Operator Regionale | Departure Time 07:29PM | Arrival Time 06:00AM | Duration 10h31 | Departure days Sat | Cheapest price $39 |
Operator Intercity | Departure Time 07:46PM | Arrival Time 06:00AM | Duration 10h14 | Departure days Sat | Cheapest price $43 |
Operator Regionale | Departure Time 07:55PM | Arrival Time 06:00AM | Duration 10h05 | Departure days Sat | Cheapest price $39 |
Operator Regionale | Departure Time 08:14PM | Arrival Time 06:00AM | Duration 9h46 | Departure days Sat | Cheapest price $39 |
Operator Intercity | Departure Time 08:16PM | Arrival Time 06:00AM | Duration 9h44 | Departure days Sat | Cheapest price $54 |
Operator Itabus | Departure Time 09:55PM | Arrival Time 04:00AM | Duration 6h05 | Departure days Fri | Cheapest price $31 |
Operator Regionale | Departure Time 09:56PM | Arrival Time 06:00AM | Duration 8h04 | Departure days Sat | Cheapest price $39 |
Operator Itabus | Departure Time 10:25PM | Arrival Time 05:50AM | Duration 7h25 | Departure days Fri | Cheapest price $19 |
Operator Itabus | Departure Time 11:55PM | Arrival Time 06:00AM | Duration 6h05 | Departure days Mon, Sun | Cheapest price $27 |
The table below shows live departures for Santa Margherita Ligure to Rome buses for today, Sunday, June 21. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 4:05 PM Chiavari, Corso G. B. Assarotti (Stazione FS) | 14h00 | 6:05 AM Roma, Autostazione (Metro Anagnina) | 1 transfer | |
FlixBus · FlixBus | 4:05 PM Chiavari, Corso G. B. Assarotti (Stazione FS) | 13h30 | 5:35 AM Roma, Autostazione Tiburtina | 1 transfer | |
FlixBus · FlixBus | 4:20 PM Zoagli, SS 1 (Pedonale per Semorile) | 13h15 | 5:35 AM Roma, Autostazione Tiburtina | 1 transfer | |
FlixBus · FlixBus | 4:20 PM Zoagli, SS 1 (Pedonale per Semorile) | 13h45 | 6:05 AM Roma, Autostazione (Metro Anagnina) | 1 transfer | |
FlixBus · FlixBus | 4:35 PM Rapallo, Rapallo | 13h00 | 5:35 AM Roma, Autostazione Tiburtina | 1 transfer | |
FlixBus · FlixBus | 4:35 PM Rapallo, Rapallo | 13h30 | 6:05 AM Roma, Autostazione (Metro Anagnina) | 1 transfer | |
061 · 055 | 7:05 PM Genoa, Piazza della Vittoria | 9h25 | 4:30 AM Roma, Autostazione Tiburtina | 1 transfer | |
1801 | 11:55 PM Genova, Via Fanti D'Italia | 6h05 | 6:00 AM Roma, Autostazione Tiburtina | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Santa Margherita Ligure to Rome run on average 13 times per day, taking around 7h 30m. Cheap bus tickets for this journey start at $13 (€11) if you book in advance.
There are 10 buses per day. The earliest bus runs at 00:02, the last at 23:55. The fastest bus covers the 236 miles (380 km) distance in 6h 5m.
Distance 236 miles (380 km) |
Average bus duration 7h 30m |
Cheapest ticket price $13 (€11) |
Buses per day 13 |
Direct buses 10 |
Fastest bus 6h 5m |
First bus 12:02 AM |
Last bus 11:55 PM |
Cheapest Month Feb |
Cheapest Day Sun |
High Season Jul - Sep |
Low Season Oct - Dec |
Busiest Day Wed |
Least Busy Day Thu |
Best time to book 14 days |
Discover the best of Rome — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Rome trip today.
One of the world’s greatest museum complexes, known for classical sculpture, Renaissance masterpieces, and the Sistine Chapel. Advance booking is strongly recommended due to very high demand.
A celebrated villa museum with major works by Bernini, Caravaggio, and Canova, set inside Villa Borghese gardens. Timed-entry tickets are required and usually need advance reservation.
The city’s historic civic museums on Capitoline Hill, featuring Roman bronzes, sculpture, paintings, and superb views over the Forum area.
A grand Baroque square lined with fountains, churches, and elegant facades. It remains one of Rome’s classic walking and people-watching spots.
A famous monumental staircase linking Piazza di Spagna with Trinità dei Monti, popular for photos, shopping nearby, and city atmosphere.
A characterful district of narrow lanes, ivy-covered facades, and lively evening atmosphere, widely loved for wandering and street photography.
A classic Roman pasta with Pecorino Romano and black pepper. It is one of the city’s most iconic dishes for its simplicity and bold flavor.
Traditional Roman pasta made with guanciale, egg yolk, Pecorino Romano, and black pepper. It is a defining dish of Rome and should not contain cream.
Pasta with tomato, guanciale, Pecorino Romano, and chili. Though linked with Amatrice, it is a staple on Roman menus and deeply rooted in local cooking.
A historic trattoria near the Pantheon, respected for traditional Roman dishes such as carbonara, amatriciana, and seasonal specialties in an intimate atmosphere.
A celebrated central Rome dining room and delicatessen known for classic Roman pasta, cured meats, and an exceptional wine list in a lively upscale setting.
A famous Trastevere trattoria known for authentic Roman comfort food, including cacio e pepe, meatballs, and artichokes, with a classic casual feel.
Moderate for Western Europe: food and coffee can be reasonable, but hotels and major tourist areas cost more.
Service is often included or modest. Locals may round up or leave EUR 1-2 for coffee, 5-10% for good restaurant service; tips are appreciated, not required.
Official public transport app
Rome, Via Marsala / Viale Enrico De Nicola -> Roma Termini
Find answers to the most common questions about traveling from Santa Margherita Ligure to Rome by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Rome, this guide helps you travel smarter and with confidence.

Most Santa Margherita Ligure to Rome buses use the Genova, Via Fanti D'Italia to Roma, Autostazione Tiburtina station pair, with some services arriving at Roma, Autostazione (Metro Anagnina). Use this guide to compare Santa Margherita Ligure and Rome bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Fiumicino, Aeroporto Leonardo de Vinci (T3 Arrivi - Stazione degli autobus) is 3 km from Rome city centre. Public transport options include:
Fiumicino, Aeroporto Leonardo de Vinci (T3 Arrivi - Stazione degli autobus) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Ristorante Italiano (in the station), Fast Food Express (in the station), Caffè del Terminal (in the station).
Free Wi-Fi. ATMs are located near the arrivals area.
Ticket office support is available at Fiumicino, Aeroporto Leonardo de Vinci (T3 Arrivi - Stazione degli autobus).
Available at Fiumicino, Aeroporto Leonardo de Vinci (T3 Arrivi - Stazione degli autobus): Parking, Taxis, WC.
Accessibility facilities are available at Fiumicino, Aeroporto Leonardo de Vinci (T3 Arrivi - Stazione degli autobus): Elevators, ramps.
Here are some other resources that might have the information you need