- Must visit
Mississippi Museum of Art
Leading art museum in downtown Jackson with American, regional, and rotating exhibitions, plus a sculpture garden and strong public programs.
Omio recommends booking the bus as it is the most popular option from Santa Ana, CA to Jackson, MS among Omio's users. If you are prioritising price take the bus with prices starting from $509. For those with little time consider booking a bus which can get you there in 48h 13m. The ticket price range depends on the travel mode: a bus costs an average of $509, and a bus costs an average of $509.
Distance: 1601 miles (2578 km)
Most popular Bus | Driving |
|---|---|
$522 Average price Cheapest | $370 Average price (fuel + tolls) |
48h 43m Average total duration Fastest 48h 13m Onboard + 30m Additional time* | 26h 25m Average total duration (door-to-door) |
Direct Options | Direct Options |
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound USA | Departure Time 08:05AM | Arrival Time 01:10PM | Duration 53h05 | Departure days Tue, Wed, Thu, Fri, Sat | Cheapest price $509 |
Operator Greyhound Mexico | Departure Time 09:20PM | Arrival Time 04:40PM | Duration 43h20 | Departure days Tue, Wed, Thu, Fri, Sat | Cheapest price $534 |
Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Santa Ana, CA to Jackson, MS run on average 3 times per day, taking around 48h 13m. Cheap bus tickets for this journey start at $509 (€410) if you book in advance.
The earliest bus runs at 08:05, the last at 21:20. The fastest bus covers the 1601 miles (2578 km) distance in 43h 20m.
Distance 1601 miles (2578 km) |
Average bus duration 48h 13m |
Cheapest ticket price $509 (€410) |
Buses per day 3 |
Fastest bus 43h 20m |
First bus 8:05 AM |
Last bus 9:20 PM |
High Season Jan - Mar |
Low Season Jan - Mar |
Discover the best of Jackson — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Jackson trip today.
Leading art museum in downtown Jackson with American, regional, and rotating exhibitions, plus a sculpture garden and strong public programs.
State history museum covering Mississippi from prehistory to the present through immersive exhibits and artifacts in a modern shared complex.
Powerful museum documenting the struggle for civil rights in Mississippi through multimedia galleries and major historical interpretation.
Trendy neighborhood known for local shops, murals, events, and a creative atmosphere popular with locals and visitors.
Major urban green space offering trails, lake scenery, and access to museums, making it one of Jackson's top outdoor areas.
Pleasant central grounds around the capitol, good for architecture views, photos, and a short downtown walk.
A Delta specialty of seasoned meat wrapped in cornmeal and corn husks, then simmered. They are a beloved Mississippi comfort food with roots in regional Southern and Mexican influences.
Farm-raised catfish, usually cornmeal-crusted and fried, is one of Mississippi's signature dishes. In Jackson, it is a classic served with hush puppies, slaw, or greens.
Creamy stone-ground grits topped with Gulf shrimp, often finished with gravy, bacon, or peppers. It reflects the strong Southern and Gulf Coast influence on Jackson dining.
An established Fondren favorite known for upscale Southern cooking, seafood, and steaks. It offers a polished neighborhood bistro atmosphere and a strong local reputation.
A historic diner and soda fountain in Fondren, known for burgers, sandwiches, shakes, and retro charm. It is one of Jackson's best-known casual dining institutions.
A well-known Jackson restaurant blending Southern ingredients with wood-fired cooking. Popular for refined but approachable dishes in a stylish, contemporary setting.
Costs are moderate for U.S. tourists. Lodging can rise in peak seasons, while casual dining stays fairly reasonable.
Tip 18-20% in restaurants before tax. USD 1-2 per drink at bars, round up or tip 10-15% for taxis, and tip hotel staff and guides for good service.
Find answers to the most common questions about traveling from Santa Ana, CA to Jackson, MS by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Jackson, MS, this guide helps you travel smarter and with confidence.

Here are some other resources that might have the information you need