The cheapest and fastest trains from Santa Ana, CA to Chicago, IL
Cheapest price
$532
Average price
$532
Fastest journey
1 d 21 h 16 m
Average duration
1 d 21 h 16 m
Trains per day
1
Distance
2787 km
The best way to find a cheap train ticket from Santa Ana, CA to Chicago, IL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Santa Ana, CA to Chicago, IL will cost around $532 if you buy it on the day, but the cheapest tickets can be found for only $532.
It's difficult to get from Santa Ana, CA to Chicago, IL without transferring at least once.


Travel Information
Compare train, bus, and flight for Santa Ana, CA to Chicago, IL
Omio recommends booking the train as it is the most popular option from Santa Ana, CA to Chicago, IL among Omio's users. If you are prioritising price take the bus with prices starting from €102. For those with little time consider booking a flight which can get you there in 4h 9m. The ticket price range depends on the travel mode: a bus costs an average of €102, and a flight costs an average of €168.
Distance: 1731 miles (2787 km)
Compare train with
Most popular Train | Flight | Bus |
|---|---|---|
€214 Average price | €288 Average price | €172 Average price Cheapest |
43h 18m Average total duration 42h 48m Onboard + 30m Additional time* | 7h 9m Average total duration Fastest 4h 9m Onboard + 3h 0m Additional time* | 53h 11m Average total duration 52h 41m Onboard + 30m Additional time* |
Direct Options | Direct Options | Direct Options |
Live departures
Santa Ana, CA to Chicago, IL train times
The table below shows live departures for Santa Ana, CA to Chicago, IL trains for today, Wednesday, November 26. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 5:26 PM Santa Ana, CA | 45h16 | 2:42 PM Chicago, IL | 1 transfer | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Santa Ana, CA to Chicago, IL by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Nov 27
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Nov 30
Dec 01
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Dec 03
Why should you book Santa Ana to Chicago trains with Omio?
Amtrak as well as Metrolink Trains offer trains services from Santa Ana to Chicago. Omio is an official ticket reseller for all your travel options from Santa Ana to Chicago.
Why book with Omio vs Amtrak?
- Compare with other providers: On Omio, you can not only buy tickets for Amtrak, but also compare tickets for the likes of Metrolink Trains to find the best option for your trip from Santa Ana to Chicago.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Amtrak with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Santa Ana to Chicago.
Why book with Omio over Trainline and Rail Europe?
- Multiple travel company options: While Amtrak tickets can be bought on Amtrak's website or third party sellers, Omio allows you to compare with the likes of Metrolink Trains to help you choose the right option for your journey from Santa Ana to Chicago.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Santa Ana to Chicago.
Journey information
Overview: Train from Santa Ana, CA to Chicago, IL
Trains from Santa Ana, CA to Chicago, IL run on average 2 times per day, taking around 42h 48m. Cheap train tickets for this journey start at $203 (€165) but you can travel from only $126 (€102) by bus.
The earliest train runs at 07:40, the last at 18:21. The fastest train covers the 1731 miles (2787 km) distance in 44h 38m.
Distance 1731 miles (2787 km) |
Average train duration 42h 48m |
Cheapest ticket price $203 (€165) |
Trains per day 2 |
Fastest train 44h 38m |
First train 07:40 |
Last train 18:21 |
Train companies: Amtrak, Metrolink Trains from Santa Ana, CA to Chicago, IL trainsAmtrak, Metrolink Trains trains will get you between Santa Ana, CA and Chicago, IL from $126 (€102). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Amtrak
Metrolink Trains
FAQs: Trains from Santa Ana, CA to Chicago, IL
Find answers to the most common questions about traveling from Santa Ana, CA to Chicago, IL by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Chicago, IL, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Santa Ana, CA to Chicago, IL
- 6:00 AM - 10:00 PM Monday - Sunday
- Parking is available with several spaces for both short-term and long-term parking.
- The Olde Ship British Pub & Restaurant
- Chapter One: the modern local
- Outside the main entrance.
- Ramps.
- $0.50
- DoubleTree by Hilton Santa Ana
- Courtyard by Marriott Santa Ana
- Holiday Inn Santa Ana-Orange County Airport
- Located in the main hall
- Located in the main hall
- Free
- Hall 1: main entrance, ticket office, and waiting area
- Hall 2: platforms for Amtrak and Metrolink services
- Bus: OCTA routes 53, 83, 206
- Train: Amtrak Pacific Surfliner, Metrolink Orange County Line
- 5:00 AM - 12:00 AM Monday - Sunday
- Free
- The car park is open 7 days a week from 5:00 a.m. to 12:00 a.m. Departures can be made outside of opening hours. Access via Canal Street.
- The Chicago Firehouse Restaurant
- Lou Mitchell's
- Outside the main entrance.
- Elevators, ramps, restrooms.
- $1
- The Kimpton Gray Hotel
- JW Marriott Chicago
- W Chicago - City Center
- Located in the main hall
- Located in the main hall
- Avis
- Budget
- Enterprise
- Located in the main hall
- Free
- Hall 1: main entrance, Amtrak services
- Hall 2: Metra services
- Hall 3: food court and retail shops
- Bus: Several lines available
- CTA: Blue Line, Pink Line
Most popular train connections from Santa Ana, CA
More options for your journey from Santa Ana, CA to Chicago, IL
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