Travel Information
Compare bus and train for Santa Ana, CA to Palo Alto, CA
Omio recommends booking the train as it is the most popular option from Santa Ana, CA to Palo Alto, CA among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $87 For those with little time, consider booking a train, which has an average total journey time of 12h 43m. Average ticket prices depend on the travel mode: a bus costs an average of $87, while a train costs an average of $149.
Distance: 350 miles (564 km)
Compare bus with
| Bus | Most popular Train | Driving |
|---|---|---|
$87 Average price Cheapest | $149 Average price | $80 Average price (fuel + tolls) |
15h 25m Average total duration 14h 55m Onboard + 30m Additional time* | 12h 43m Average total duration Fastest 12h 13m Onboard + 30m Additional time* | 6h 16m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Santa Ana, CA to Palo Alto, CA:
A bus is $62 (€50) less than a train for this route with tickets for a train from Santa Ana, CA to Palo Alto, CA costing on average $149 (€121).
Other travel options to Palo Alto, CA take longer:
Bus takes on average 14h 55m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
Santa Ana, CA to Palo Alto, CA Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 07:40AM | Arrival Time 09:05PM | Duration 13h25 | Departure days Wed | Cheapest price $56 |
Operator Greyhound | Departure Time 09:25PM | Arrival Time 06:20AM | Duration 8h55 | Departure days Wed | Cheapest price $100 |
Operator Greyhound | Departure Time 09:45PM | Arrival Time 06:20AM | Duration 8h35 | Departure days Wed | Cheapest price $100 |
Journey information
Overview: Bus from Santa Ana, CA to Palo Alto, CA
Buses from Santa Ana, CA to Palo Alto, CA run on average 3 times per day, taking around 14h 55m. Cheap bus tickets for this journey start at $57 (€46) if you book in advance.
The earliest bus runs at 00:05, the last at 14:48. The fastest bus covers the 350 miles (564 km) distance in 14h 55m.
Distance 350 miles (564 km) |
Average bus duration 14h 55m |
Cheapest ticket price $57 (€46) |
Buses per day 3 |
Fastest bus 14h 55m |
First bus 12:05 AM |
Last bus 2:48 PM |
Cheapest Month Jul |
Cheapest Day Sat |
High Season Jul - Sep |
Low Season Oct - Dec |
FAQs: Bus from Santa Ana, CA to Palo Alto, CA
Find answers to the most common questions about traveling from Santa Ana, CA to Palo Alto, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Palo Alto, CA, this guide helps you travel smarter and with confidence.

- Stanford University, a prestigious educational institution known for its beautiful campus and iconic Hoover Tower
- Palo Alto Baylands Nature Preserve, a vast marshland offering trails and opportunities for birdwatching
- Cantor Arts Center, an art museum featuring an extensive collection of sculptures and diverse exhibits
- Elizabeth F. Gamble Garden, a historic estate with beautifully maintained gardens open to the public
- Computer History Museum, a museum dedicated to preserving and presenting the history of computing and technology.
- Stanford Shopping Center, indulge in high-end shopping and dining at this open-air mall
- Rinconada Park, enjoy a relaxing day with picnic areas, playgrounds, and a swimming pool
- Palo Alto Art Center, explore contemporary art exhibitions and participate in community art programs
- Foothills Park, hike through scenic trails and enjoy panoramic views of the Bay Area
- Junior Museum & Zoo, a family-friendly destination with interactive science exhibits and live animal displays.
popular bus stations
Popular bus stations from Santa Ana, CA to Palo Alto, CA
Most Santa Ana, CA to Palo Alto, CA buses use the Santa Ana, E Santa Ana Blvd (Train Station) to Oakland, West Oakland BART Station station pair. Use this guide to compare Santa Ana, CA and Palo Alto, CA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Which Santa Ana, CA station do buses to Palo Alto, CA leave from?
Getting to Santa Ana, E Santa Ana Blvd (Train Station) from Santa Ana city centre
Santa Ana, E Santa Ana Blvd (Train Station) is 1 km from Santa Ana city centre. Public transport options include:
Santa Ana, E Santa Ana Blvd (Train Station) bus station facilities and services
Santa Ana, E Santa Ana Blvd (Train Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Santa Ana, E Santa Ana Blvd (Train Station). ATMs are available at Santa Ana, E Santa Ana Blvd (Train Station).
Tickets and information
Ticket office support is available at Santa Ana, E Santa Ana Blvd (Train Station).
Parking, taxis and toilets
Available at Santa Ana, E Santa Ana Blvd (Train Station): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Santa Ana, E Santa Ana Blvd (Train Station): Bus access is available.
Most popular bus connections from Santa Ana, CA
More options for your journey from Santa Ana, CA to Palo Alto, CA
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