Travel Information
Compare train and bus for Santa Ana, CA to San Diego, CA
Omio recommends booking the train as it is the most popular option from Santa Ana, CA to San Diego, CA among Omio's users. If you are prioritising price, take the train, with an average ticket price of $32 For those with little time, consider booking a bus, which has an average total journey time of 2h 25m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.0 - 0.1kg. Average ticket prices depend on the travel mode: a train costs an average of $32, while a bus costs an average of $39.
Distance: 82 miles (132 km)
Compare train with
Most popular Train | Bus | Driving |
|---|---|---|
$32 Average price Cheapest | $39 Average price | $19 Average price (fuel + tolls) |
2h 27m Average total duration 1h 57m Onboard + 30m Additional time* | 2h 25m Average total duration Fastest 1h 55m Onboard + 30m Additional time* | 1h 28m Average total duration (door-to-door) |
0.0 - 0.1kg CO2 emissions Lowest | 0.1 - 0.3kg CO2 emissions | - CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Santa Ana, CA to San Diego, CA:
A train is $7 (€6) less than a bus for this route with tickets for a bus from Santa Ana, CA to San Diego, CA costing on average $39 (€33).
Other travel options to San Diego, CA take longer:
Train takes on average 2h 27m.
Tickets start at around $32 (€27) compared to roughly $19 (€16) in fuel and tolls — a saving of about $-13.22 (€-11.05). The journey takes 1h 57m versus 1h 28m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
Travel optionsfrom Santa Ana, CA to San Diego, CA
How to get from Santa Ana, CA to San Diego, CA by train, bus or flight.
Our recommendation
The best way to travel from Santa Ana, CA to San Diego, CA is by taking a bus because it’s the best combination of price and speed.
FlixBus8:30 PM1h45Santa Ana, E Santa Ana Blvd (Train Station)10:15 PMSan Diego, West Harbor Drive (The Headquarters at Seaport District), CA$251One-way0 transfers
Cheapest
FlixBus8:30 PM1h45Santa Ana, E Santa Ana Blvd (Train Station)10:15 PMSan Diego, West Harbor Drive (The Headquarters at Seaport District), CA$251One-way0 transfers
Fastest
02:44 PM1h05Santa Ana, CA3:49 PMSan Diego, CA$431One-way0 transfers
Other options
FlixBus8:30 PM2h15Santa Ana, E Santa Ana Blvd (Train Station)10:45 PMSan Diego, San Ysidro Transit Center$291One-way0 transfers
10:05 PM1h45Santa Ana, E Santa Ana Blvd (Train Station)11:50 PMSan Diego, Congress Street (Old Town Park), CA$411One-way0 transfers
FlixBus2:35 PM1h50Santa Ana, E Santa Ana Blvd (Train Station)4:25 PMSan Diego, Congress Street (Old Town Park), CA$411One-way0 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Santa Ana, CA to San Diego, CA
Travel to San Diego, CA easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Santa Ana, CA to San Diego, CA.

This is compared to other travel options from Santa Ana, CA to San Diego, CA:
A train is $7 (€6) less than a bus for this route with tickets for a bus from Santa Ana, CA to San Diego, CA costing on average $39 (€33).
Other travel options to San Diego, CA take longer:
Train takes on average 2h 27m.
- Around 24 trains per day.
- Around 11 buses per day.
However, we recommend checking specific travel dates for your route between Santa Ana, CA and San Diego, CA as scheduled services by train and bus can vary by season or day of the week.
- Flights mostly depart from John Wayne Airport and arrive in San Diego International Airport.
- Trains mostly depart from Santa Ana Station, Santa Ana, CA and arrive in Santa Fe Depot, San Diego, CA.
- Buses mostly depart from Santa Ana, E Santa Ana Blvd (Train Station) and arrive in San Diego, CA.
- Travel with FlixBus, Greyhound, Futura Net to go to San Diego, CA by bus.
- Travel with Amtrak to go to San Diego, CA by train.
- 11 direct buses per day with FlixBus, Greyhound, Futura Net.
- 24 direct trains per day with Amtrak.
Travelling from Santa Ana, CA to San Diego, CA: related information
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