Journey information
Overview: San Diego, CA to South San Francisco, CA flight
Flights from San Diego, CA to South San Francisco, CA depart on average 86 times per day, taking around 3h 24m. Cheap flight tickets for this journey start at $117 (€94) but you can travel from only $68 (€55) by bus.
There are 16 flights per day. The earliest flight runs at 00:30, the last at 23:58. The fastest flight covers the 451 miles (727 km) distance in 1h 44m. February is the cheapest month to fly.
Distance 451 miles (727 km) |
Average flight duration 3h 24m |
Cheapest ticket price $117 (€94) |
Flights per day 86 |
Direct flights 16 |
Fastest flight 1h 44m |
First flight 12:30 AM |
Last flight 11:58 PM |
Cheapest Month Feb |
Cheapest Day Sun |
High Season Apr - Jun |
Low Season Jul - Sep |
The cheapest and fastest flights from San Diego, CA to South San Francisco, CA
Cheapest price
$144
Average price
$218
Fastest journey
1 h 53 m
Average duration
3 h 59 m
Flights per day
2
Distance
727 km
The best way to find a cheap flight ticket from San Diego, CA to South San Francisco, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from San Diego, CA to South San Francisco, CA will cost around $218 if you buy it on the day, but the cheapest tickets can be found for only $144.
Of the 2 flights that leave San Diego, CA for South San Francisco, CA onSat, May 23, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sat, May 23 the direct flights cover the 727 km distance in an average of 3 h 59 m but if you time it right, some flights will get you there in just 1 h 53 m .
On Sat, May 23 the longest flights will take 6 h 4 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
3:59 AM1h53San Diego, CA5:52 AMSouth San Francisco, CA$1441One-way0 transfers
11:32 PM6h04San Diego, CA5:36 AMSouth San Francisco, CA$2921One-way0 transfers
3:59 AM1h53San Diego, CA5:52 AMSouth San Francisco, CA$1441One-way0 transfers
11:32 PM6h04San Diego, CA5:36 AMSouth San Francisco, CA$2921One-way0 transfers
Travel Information
Compare bus, train, and flight for San Diego, CA to South San Francisco, CA
Omio recommends booking the flight as it is the most popular option from San Diego, CA to South San Francisco, CA among Omio's users. If you are prioritising price take the bus with prices starting from $68. For those with little time consider booking a flight which can get you there in 3h 24m. The ticket price range depends on the travel mode: a bus costs an average of $68, and a flight costs an average of $117.
Distance: 451 miles (727 km)
Compare flight with
Most popular Flight | Train | Bus | Driving |
|---|---|---|---|
$194 Average price | $89 Average price | $79 Average price Cheapest | $102 Average price (fuel + tolls) |
6h 24m Average total duration Fastest 3h 24m Onboard + 3h 0m Additional time* | 14h 33m Average total duration 14h 3m Onboard + 30m Additional time* | 14h 9m Average total duration 13h 39m Onboard + 30m Additional time* | 8h 3m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from San Diego, CA to South San Francisco, CA:
A bus is $11 (€9) less than a train for this route with tickets for a train from San Diego, CA to South San Francisco, CA costing on average $89 (€73).
A bus is $115 (€93) less than a flight for this route with tickets for a flight from San Diego, CA to South San Francisco, CA costing on average $194 (€157).
Other travel options to South San Francisco, CA take longer:
Bus takes on average 13h 39m.
Train takes on average 14h 3m.
Live departures
San Diego, CA to South San Francisco, CA flight times
The table below shows live departures for San Diego, CA to South San Francisco, CA flights for tomorrow, Friday, May 22. You can also manually refresh the results below to see updated flight journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 3:59 AM San Diego, CA | 1h53 | 5:52 AM South San Francisco, CA | 0 transfersDirect | |
This is the last flight of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets San Diego, CA to South San Francisco, CA by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
May 22
May 23
May 24
May 25
May 26
May 27
May 28
FAQs: San Diego, CA to South San Francisco, CA Flight
Find answers to the most common questions about traveling from San Diego, CA to South San Francisco, CA by flight. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest flight, the cheapest option, or tips for making the most of your visit at South San Francisco, CA, this guide helps you travel smarter and with confidence.

popular airports
Popular airports from San Diego, CA to South San Francisco, CA
- Free Wi-Fi available throughout the airport.
- Shops in terminals 1 and 2, including Duty-Free and Hudson News.
- Parking available, price varies.
- Restaurants in terminals 1 and 2, including fast food and sit-down options like The Counter and Phil's BBQ
- Available outside the terminal.
- Elevators, ramps
- Available throughout the airport.
- Hotels nearby, Sheraton San Diego Hotel & Mari within walking distance.
- Showers available at the Airspace Lounge, access fee required.
- Lounges available, including United Club and Airspace Lounge.
- Lost and Found located in terminal 2 East, baggage claim area.
- Car rental services available at Rental Car Center, free shuttle from terminals
- Bus Route 992, Airport Station, 4.8 km
- The place has an entrance that is wheelchair-accessible
More options for your journey from San Diego, CA to South San Francisco, CA
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