Journey information
Overview: San Diego, CA to South San Francisco, CA flight
Flights from San Diego, CA to South San Francisco, CA depart on average 69 times per day, taking around 2h 28m. Cheap flight tickets for this journey start at $116 (€94) but you can travel from only $72 (€59) by bus.
There are 14 flights per day. The earliest flight runs at 00:25, the last at 23:58. The fastest flight covers the 451 miles (727 km) distance in 1h 49m. December is the cheapest month to fly.
Distance 451 miles (727 km) |
Average flight duration 2h 28m |
Cheapest ticket price $116 (€94) |
Flights per day 69 |
Direct flights 14 |
Fastest flight 1h 49m |
Cheapest month December |
First flight 12:25 AM |
Last flight 11:58 PM |
Travel Information
Compare bus, train, and flight for San Diego, CA to South San Francisco, CA
Omio recommends booking the flight as it is the most popular option from San Diego, CA to South San Francisco, CA among Omio's users. If you are prioritising price take the bus with prices starting from $72. For those with little time consider booking a flight which can get you there in 2h 28m. The ticket price range depends on the travel mode: a bus costs an average of $72, and a flight costs an average of $116.
Distance: 451 miles (727 km)
Compare flight with
Most popular Flight | Train | Bus |
|---|---|---|
$226 Average price | $97 Average price | $86 Average price Cheapest |
5h 28m Average total duration Fastest 2h 28m Onboard + 3h 0m Additional time* | 14h 37m Average total duration 14h 7m Onboard + 30m Additional time* | 14h 6m Average total duration 13h 36m Onboard + 30m Additional time* |
Direct Options | Direct Options | Direct Options |
Live departures
San Diego, CA to South San Francisco, CA flight times
The table below shows live departures for San Diego, CA to South San Francisco, CA flights for today, Thursday, April 2. You can also manually refresh the results below to see updated flight journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 3:45 PM San Diego, CA | 1h49 | 5:34 PM South San Francisco, CA | 0 transfersDirect | |
This is the last flight of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets San Diego, CA to South San Francisco, CA by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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FAQs: San Diego, CA to South San Francisco, CA Flight
Find answers to the most common questions about traveling from San Diego, CA to South San Francisco, CA by flight. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest flight, the cheapest option, or tips for making the most of your visit at South San Francisco, CA, this guide helps you travel smarter and with confidence.

popular airports
Popular airports from San Diego, CA to South San Francisco, CA
- Free Wi-Fi available throughout the airport.
- Shops in terminals 1 and 2, including Duty-Free and Hudson News.
- Parking available, price varies.
- Restaurants in terminals 1 and 2, including fast food and sit-down options like The Counter and Phil's BBQ
- Available outside the terminal.
- Elevators, ramps
- Available throughout the airport.
- Hotels nearby, Sheraton San Diego Hotel & Mari within walking distance.
- Showers available at the Airspace Lounge, access fee required.
- Lounges available, including United Club and Airspace Lounge.
- Lost and Found located in terminal 2 East, baggage claim area.
- Car rental services available at Rental Car Center, free shuttle from terminals
- Bus Route 992, Airport Station, 4.8 km
More options for your journey from San Diego, CA to South San Francisco, CA
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