San Diego, CA to South San Francisco, CA Flights

Thu, Jul 09
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Journey information

Overview: San Diego, CA to South San Francisco, CA flight

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Flights from San Diego, CA to South San Francisco, CA depart on average 86 times per day, taking around 3h 24m. Cheap flight tickets for this journey start at $115 (€94) but you can travel from only $67 (€55) by bus.

There are 16 flights per day. The earliest flight runs at 00:30, the last at 23:58. The fastest flight covers the 451 miles (727 km) distance in 1h 44m. February is the cheapest month to fly.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $67 (€55)
Distance
451 miles (727 km)
Average flight duration
3h 24m
Cheapest ticket price
$115 (€94)
Flights per day
86
Direct flights
16
Fastest flight
1h 44m
First flight
12:30 AM
Last flight
11:58 PM
Cheapest Month
Feb
Cheapest Day
Sun
High Season
Apr - Jun
Low Season
Jul - Sep
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $67 (€55)

Travel Information

Compare bus, train, and flight for San Diego, CA to South San Francisco, CA

Omio recommends booking the flight as it is the most popular option from San Diego, CA to South San Francisco, CA among Omio's users. If you are prioritising price take the bus with prices starting from $67. For those with little time consider booking a flight which can get you there in 3h 24m. The ticket price range depends on the travel mode: a bus costs an average of $67, and a flight costs an average of $115.

Distance: 451 miles (727 km)

Compare flight with

Most popular
Flight
Train
Bus
Driving

$191

Average price

$88

Average price

$77

Average price

Cheapest

$100

Average price

(fuel + tolls)

6h 24m

Average total duration

Fastest

3h 24m

Onboard

+

3h 0m

Additional time*

14h 33m

Average total duration

14h 3m

Onboard

+

30m

Additional time*

14h 9m

Average total duration

13h 39m

Onboard

+

30m

Additional time*

8h 3m

Average total duration

(door-to-door)

Direct Options

Direct Options

Direct Options

Direct Options

The cheapest way to travel from San Diego, CA to South San Francisco, CA is a bus with an average price of $77 (€64).

This is compared to other travel options from San Diego, CA to South San Francisco, CA:

A bus is $11 (€9) less than a train for this route with tickets for a train from San Diego, CA to South San Francisco, CA costing on average $88 (€73).

A bus is $113 (€93) less than a flight for this route with tickets for a flight from San Diego, CA to South San Francisco, CA costing on average $191 (€157).

The fastest way to travel from San Diego, CA to South San Francisco, CA is by flight with an average journey time of 3h 24m.

Other travel options to South San Francisco, CA take longer:

Bus takes on average 13h 39m.

Train takes on average 14h 3m.

It's helpful to compare your options as there are 3 ways to travel between San Diego, CA and South San Francisco, CA including taking a bus, train, and flight.

Compare prices and tickets San Diego, CA to South San Francisco, CA by bus, train, or flight

Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

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Jul 09
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FAQs: San Diego, CA to South San Francisco, CA Flight

Find answers to the most common questions about traveling from San Diego, CA to South San Francisco, CA by flight. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest flight, the cheapest option, or tips for making the most of your visit at South San Francisco, CA, this guide helps you travel smarter and with confidence.

FAQs
Cheap plane tickets from San Diego, CA to South San Francisco, CA can start from as little as $115 (€94) when you book in advance. The average flight ticket price for San Diego, CA to South San Francisco, CA is $191 (€157) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by plane from San Diego, CA to South San Francisco, CA is 1h 44m to travel the 451 miles (727 km) long route. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest flight from San Diego, CA to South San Francisco, CA leaves at 12:30 AM. Plan your trip with the Journey Planner from Omio.
The latest flight from San Diego, CA to South San Francisco, CA leaves at 11:58 PM.
Flights from San Diego, CA to South San Francisco, CA generally leave from San Diego International Airport and arrive in San Francisco International Airport.San Diego International Airport is 2 miles (4 km) away from San Diego, CA city centre and San Francisco International Airport is 0 miles (1 km) from South San Francisco, CA city centre.
The cheapest month for a flight from San Diego, CA to South San Francisco, CA is February.
It's helpful to compare your options as there are 3 ways to travel between San Diego, CA and South San Francisco, CA including taking a bus, train, and flight.
Since neither San Diego, CA nor South San Francisco, CA are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
There is no time difference between San Diego, CA and South San Francisco, CA.
For domestic flights we recommend to arrive 1.5 to 2 hours before departure. Please check the website of your departure airport if in doubt. Some airports may offer booking time slots for security checks or offer additional information on when to get there based on time of day.
Most airlines permit carry-on bags that fit within specific dimensions (e.g., 22 x 14 x 9 inches or 56 x 36 x 23 cm), including handles and wheels. Bags must fit in the overhead bin or under the seat in front of you.
Many airlines impose weight limits, commonly ranging between 7 kg (15 lbs) and 12 kg (26 lbs). Typically, passengers are allowed one carry-on bag and one personal item (for example a purse, laptop bag, or backpack). Personal items must fit under the seat in front of you. Budget Airlines (like Ryanair or Wizz Air) have stricter size and weight limits, often requiring fees for larger carry-ons. Full-Service Airlines have more lenient policies, sometimes including more spacious dimensions or higher weight limits depending on your ticket class.
The list of items prohibited on an airplane varies by country and airline, but in general, the following items are not allowed in carry-on or checked baggage: Weapons and self-defence items, sharp objects, flammable materials, explosives, toxic substances, or liquids over 100ml (except for medications and baby essentials). In checked baggage, firearms (without authorization), explosives, large lithium batteries, and hazardous chemicals are prohibited. Electronic cigarettes must be in carry-on bags, while alcohol and dry ice have restrictions. Always check with your airline for specific regulations.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In South San Francisco, CA, travelers should be cautious of petty crimes such as pickpocketing and vehicle break-ins, especially in crowded or tourist-heavy areas. Common scams include overcharging by unlicensed taxi drivers or ride-share services, so it's advisable to use reputable transportation options. Staying aware of surroundings and securing personal belongings helps ensure a safe visit.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular airports

Popular airports from San Diego, CA to South San Francisco, CA

Most San Diego, CA to South San Francisco, CA flights use the San Diego International Airport to San Francisco International Airport airport pair. Use this guide to compare San Diego, CA and South San Francisco, CA airports on this route, check city-centre transport, alongside checking practicalities like airport facilities and services.

Departure airports in San Diego
Arrival airports in South San Francisco

Which San Diego, CA airport do flights to South San Francisco, CA leave from?

Flights from San Diego, CA to South San Francisco, CA depart from San Diego International Airport. The airport is 2 miles (4 km) from San Diego, CA city centre at 3225 N Harbor Dr, San Diego, CA 92101, USA.
San Diego International Airport (SAN)3225 N Harbor Dr, San Diego, CA 92101, USAWifiShoppingParkingDiningATMTaxisAccessibilityWCHotelShowerLoungeLost and Found OfficeCar Rental
City-centre transport

Getting to San Diego International Airport from San Diego city centre

San Diego International Airport is 4 km from San Diego city centre. Public transport options include:

Bus923, 992 · 12m · $6 · every ~10 min
923, 992 · 13m · $6 · every ~10 min

San Diego International Airport airport facilities and services

San Diego International Airport has practical services for this route, including Wifi, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Shower, Lounge, Lost and Found Office, and Car Rental.

Food and drink

Food options include: Restaurants in terminals 1 and 2, including fast food and sit-down options like The Counter and Phil's BBQ

Wi-Fi and ATMs

Free Wi-Fi available throughout the airport. ATMs are located in all terminals.

Luggage and lost property

Lost and found is available at the station.

Parking, taxis and toilets

Available at San Diego International Airport: Parking, Taxis, WC.

Bike and car services

Available at San Diego International Airport: Car Rental.

Accessibility

Accessibility facilities are available at San Diego International Airport: Elevators, ramps.

Shops, hotels and contact

Nearby hotels include Hotels nearby, Sheraton San Diego Hotel & Mari within walking distance..

McClellan-Palomar Airport (CLD)2198 Palomar Airport Rd, Carlsbad, CA 92008, USA+1 760-431-4646Accessibility
City-centre transport

Getting to McClellan-Palomar Airport from San Diego city centre

TrainPacific Surfliner · 2h 11m · $21 · every ~2 min
BusAmtrak Thruway Connecting Service · 2h 3m · $21
101 · 3h 3m · $28 · every ~4 min

McClellan-Palomar Airport airport facilities and services

McClellan-Palomar Airport has practical services for this route, including Accessibility.

Accessibility

Accessibility facilities are available at McClellan-Palomar Airport: The place has an entrance that is wheelchair-accessible.

More options for your journey from San Diego, CA to South San Francisco, CA

Here are some other resources that might have the information you need

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