South San Francisco, CA to San Diego, CA bus with SamTrans

Sat, Dec 13
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Rede Expressos
1,000+ travel companies
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The cheapest and fastest buses from South San Francisco, CA to San Diego, CA

Showing times and prices for Dec 16

Cheapest price

$239

Average price

$239

Fastest journey

14 h 37 m

Average duration

14 h 37 m

Buses per day

1

Distance

727 km

Cheap tickets

The best way to find a cheap bus ticket from South San Francisco, CA to San Diego, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from South San Francisco, CA to San Diego, CA will cost around $239 if you buy it on the day, but the cheapest tickets can be found for only $239.

Fast buses

It's difficult to get from South San Francisco, CA to San Diego, CA without transferring at least 2 times.

SamTrans
09:35PM14h37
South San Francisco, CA
12:12PMSan Diego, CA
$2391One-way
2 transfers

Travel Information

Compare bus for South San Francisco, CA to San Diego, CA

Omio recommends booking the flight as it is the most popular option from South San Francisco, CA to San Diego, CA among Omio's users. If you are prioritising price take the bus with prices starting from €60. For those with little time consider booking a flight which can get you there in 4h 19m. The ticket price range depends on the travel mode: a bus costs an average of €60, and a flight costs an average of €205.

Distance: 451 miles (727 km)

Compare bus with

Bus
Most popular
Flight
Train

€60

Average price

Cheapest

€205

Average price

€69

Average price

15h 44m

Average total duration

15h 14m

Onboard

+

30m

Additional time*

7h 19m

Average total duration

Fastest

4h 19m

Onboard

+

3h 0m

Additional time*

15h 14m

Average total duration

14h 44m

Onboard

+

30m

Additional time*

Direct Options

Direct Options

Direct Options

South San Francisco, CA to San Diego, CA Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
Amtrak
Departure Time
05:15AM
Arrival Time
08:04PM
Duration
14h49
Departure days
Wed, Thu
Cheapest price
$74
Operator
Greyhound
Departure Time
06:30AM
Arrival Time
11:50PM
Duration
17h20
Departure days
Wed, Thu
Cheapest price
$152
Operator
Amtrak
Departure Time
07:50AM
Arrival Time
11:04PM
Duration
15h14
Departure days
Wed, Thu
Cheapest price
$74
Operator
FlixBus
Departure Time
08:20AM
Arrival Time
11:50PM
Duration
15h30
Departure days
Wed, Thu
Cheapest price
$184
Operator
Greyhound
Departure Time
04:00PM
Arrival Time
01:40PM
Duration
21h40
Departure days
Wed, Thu
Cheapest price
$128
Operator
Amtrak
Departure Time
10:35PM
Arrival Time
01:07PM
Duration
14h32
Departure days
Wed, Thu
Cheapest price
$74
Operator
Greyhound
Departure Time
10:40PM
Arrival Time
11:45AM
Duration
13h05
Departure days
Wed
Cheapest price
$241

Live departures

South San Francisco, CA to San Diego, CA bus times

The table below shows live departures for South San Francisco, CA to San Diego, CA buses for today, Monday, December 15. You can also manually refresh the results below to see updated bus journeys.

Last updated at 7:58 PM
ProviderDepartsDurationArrivesTransfers
Tickets
SamTrans9:35 PM South San Francisco, CA
14h37
12:12 PM San Diego, CA2 transfers

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets South San Francisco, CA to San Diego, CA by bus

Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Tue
Dec 16
Wed
Dec 17
Thu
Dec 18
Fri
Dec 19
Sat
Dec 20
Sun
Dec 21
Mon
Dec 22

Journey information

Overview: Bus from South San Francisco, CA to San Diego, CA

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Buses from South San Francisco, CA to San Diego, CA run on average 43 times per day, taking around 15h 14m. Cheap bus tickets for this journey start at $75 (€60) if you book in advance.

There are 2 buses per day. The earliest bus runs at 04:01, the last at 23:25. The fastest bus covers the 451 miles (727 km) distance in 15h 14m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
451 miles (727 km)
Average bus duration
15h 14m
Cheapest ticket price
$75 (€60)
Buses per day
43
Direct buses
2
Fastest bus
15h 14m
First bus
04:01
Last bus
23:25
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Bus providers: SamTrans from South San Francisco, CA to San Diego, CAYou can travel by bus between South San Francisco, CA to San Diego, CA with SamTrans for as low as $75 (€60). When you search for schedules and tickets, Omio will show you the best journey

SamTrans

Luggage & cancellation policy
Average Duration
14h 37m
Cheapest Price
$239 (€191)
SamTrans frequency
1 a day

FAQs: Bus from South San Francisco, CA to San Diego, CA

Find answers to the most common questions about traveling from South San Francisco, CA to San Diego, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Diego, CA, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from South San Francisco, CA to San Diego, CA can start from as little as $269 (€215) when you book in advance. The average bus ticket price for South San Francisco, CA to San Diego, CA is $269 (€215); however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from South San Francisco, CA to San Diego, CA is 14 h 37 min   to travel the 451 mile (727 km) long trip, with around there are 53 buses per day. Journey times can vary on weekends and holidays.
The first bus from South San Francisco, CA to San Diego, CA leaves at 4: 01AM. Plan your trip with the Journey Planner   from Omio.
The last bus from South San Francisco, CA to San Diego, CA leaves at 11: 30PM.
There are 53 buses a day from South San Francisco, CA to San Diego, CA which require at least one change with SamTrans. Schedules can vary on holidays or weekends with fewer buses.
For the best South San Francisco, CA to San Diego, CA bus to book, you can travel safely and comfortably with SamTrans. However, it's always good to check all possible bus providers with services to San Diego, CA from South San Francisco, CA to compare what amenities they may offer.
The cheapest month for a bus from South San Francisco, CA to San Diego, CA is November.
Yes, you can take a bus between South San Francisco, CA and San Diego, CA.
No, the bus from South San Francisco, CA to San Diego, CA has no accessibility options.
No, there are no bathrooms on board the bus from South San Francisco, CA to San Diego, CA.
Some of the most interesting sights to explore in San Diego, CA are:
  • Balboa Park, a sprawling urban park with museums, gardens, and the San Diego Zoo
  • USS Midway Museum, a historic naval aircraft carrier museum offering interactive exhibits and tours
  • La Jolla Cove, a picturesque coastal area known for its stunning views and marine life
  • Gaslamp Quarter, a lively historic district with Victorian architecture, dining, and entertainment options
  • Coronado Beach, a beautiful sandy beach known for its gentle waves and iconic hotel.
The best things to do in San Diego, CA include:
  • Explore the vibrant art scene at the Museum of Contemporary Art San Diego
  • Enjoy a harbor cruise for stunning views of the skyline and naval ships
  • Hike the scenic trails at Torrey Pines State Natural Reserve
  • Visit the Birch Aquarium to learn about marine life and ocean conservation
  • Experience the thrill of a whale watching tour off the coast.
No, bikes are not allowed on board the bus from South San Francisco, CA to San Diego, CA.

To find the cheapest bus tickets for your trip from South San Francisco, CA to San Diego, CA, follow these tips:

  • Book in advance: Tickets are often cheaper when booked early.
  • Be flexible with dates and times: Traveling during off-peak hours or on weekdays can help you save money.
  • Use our search filters: Sort results by price to quickly identify the most affordable options.
  • Look for special deals or discounts: Check for promotions or discounts available on our website and app.
  • Start your search now and compare ticket prices to find the best deal!

    Yes, there is food available to purchase on board the bus from South San Francisco, CA to San Diego, CA.
    No, luggage for the bus from South San Francisco, CA to San Diego, CA needs to be booked in addition.
    No, there are no additional luggage options for the bus from South San Francisco, CA to San Diego, CA.
    Unfortunately, pets are not allowed on the bus from South San Francisco, CA to San Diego, CA.
    No, there are no USB plugs on board the bus from South San Francisco, CA to San Diego, CA.
    No, there is no WiFi on board the bus from South San Francisco, CA to San Diego, CA.

    popular bus stations

    Popular bus stations from South San Francisco, CA to San Diego, CA

    South San Francisco
    San Diego
    San Diego, Congress Street (Old Town Park)
    information
    San Diego, San Ysidro Transit Center
    information
    San Diego, West Harbor Drive (The Headquarters at Seaport District)
    information

    More options for your journey from South San Francisco, CA to San Diego, CA

    Here are some other resources that might have the information you need

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