4.9
4.6The cheapest and fastest buses from South San Francisco, CA to San Diego, CA
Cheapest price
$241
Average price
$241
Fastest journey
14 h 37 m
Average duration
14 h 37 m
Buses per day
1
Distance
727 km
The best way to find a cheap bus ticket from South San Francisco, CA to San Diego, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from South San Francisco, CA to San Diego, CA will cost around $241 if you buy it on the day, but the cheapest tickets can be found for only $241.
It's difficult to get from South San Francisco, CA to San Diego, CA without transferring at least 2 times.
Travel Information
Compare bus for South San Francisco, CA to San Diego, CA
Omio recommends booking the flight as it is the most popular option from South San Francisco, CA to San Diego, CA among Omio's users. If you are prioritising price take the bus with prices starting from €60. For those with little time consider booking a flight which can get you there in 4h 19m. The ticket price range depends on the travel mode: a bus costs an average of €60, and a flight costs an average of €205.
Distance: 451 miles (727 km)
Compare bus with
| Bus | Most popular Flight | Train |
|---|---|---|
€60 Average price Cheapest | €205 Average price | €69 Average price |
15h 44m Average total duration 15h 14m Onboard + 30m Additional time* | 7h 19m Average total duration Fastest 4h 19m Onboard + 3h 0m Additional time* | 15h 14m Average total duration 14h 44m Onboard + 30m Additional time* |
Direct Options | Direct Options | Direct Options |
Live departures
South San Francisco, CA to San Diego, CA bus times
The table below shows live departures for South San Francisco, CA to San Diego, CA buses for tomorrow, Monday, February 2. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| 9:35 PM South San Francisco, CA | 14h37 | 12:12 PM San Diego, CA | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets South San Francisco, CA to San Diego, CA by bus
Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Feb 02
Feb 03
Feb 04
Feb 05
Feb 06
Feb 07
Feb 08
Journey information
Overview: Bus from South San Francisco, CA to San Diego, CA
USAUSA
Buses from South San Francisco, CA to San Diego, CA run on average 43 times per day, taking around 15h 14m. Cheap bus tickets for this journey start at $76 (€60) if you book in advance.
There are 2 buses per day. The earliest bus runs at 04:01, the last at 23:25. The fastest bus covers the 451 miles (727 km) distance in 15h 14m.
Distance 451 miles (727 km) |
Average bus duration 15h 14m |
Cheapest ticket price $76 (€60) |
Buses per day 43 |
Direct buses 2 |
Fastest bus 15h 14m |
First bus 04:01 |
Last bus 23:25 |
Bus providers: SamTrans from South San Francisco, CA to San Diego, CAYou can travel by bus between South San Francisco, CA to San Diego, CA with SamTrans for as low as $76 (€60). When you search for schedules and tickets, Omio will show you the best journey
SamTrans
FAQs: Bus from South San Francisco, CA to San Diego, CA
Find answers to the most common questions about traveling from South San Francisco, CA to San Diego, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Diego, CA, this guide helps you travel smarter and with confidence.
- Balboa Park, a sprawling urban park with museums, gardens, and the San Diego Zoo
- USS Midway Museum, a historic naval aircraft carrier museum offering interactive exhibits and tours
- La Jolla Cove, a picturesque coastal area known for its stunning views and marine life
- Gaslamp Quarter, a lively historic district with Victorian architecture, dining, and entertainment options
- Coronado Beach, a beautiful sandy beach known for its gentle waves and iconic hotel.
- Explore the vibrant art scene at the Museum of Contemporary Art San Diego
- enjoy a harbor cruise for stunning views of the skyline and naval ships
- hike the scenic trails at Torrey Pines State Natural Reserve
- visit the Birch Aquarium to learn about marine life and ocean conservation
- experience the thrill of a whale watching tour off the coast.
popular bus stations
Popular bus stations from South San Francisco, CA to San Diego, CA
More options for your journey from South San Francisco, CA to San Diego, CA
Here are some other resources that might have the information you need
Most popular buses to and from San Diego, CA and South San Francisco, CA
The Omio App Makes Travel Planning Easy
We’ll get you where you want to go. From live train updates to mobile tickets, our innovative app is the ideal way to plan and keep track of your travel.
