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Travel Information
Compare bus, train, and flight for South San Francisco, CA to San Diego, CA
Omio recommends booking the flight as it is the most popular option from South San Francisco, CA to San Diego, CA among Omio's users. If you are prioritising price take the bus with prices starting from $71. For those with little time consider booking a flight which can get you there in 2h 47m. The ticket price range depends on the travel mode: a bus costs an average of $71, and a flight costs an average of $82.
Distance: 451 miles (727 km)
Compare bus with
| Bus | Most popular Flight | Train |
|---|---|---|
$72 Average price Cheapest | $238 Average price | $83 Average price |
15h 48m Average total duration 15h 18m Onboard + 30m Additional time* | 5h 47m Average total duration Fastest 2h 47m Onboard + 3h 0m Additional time* | 15h 19m Average total duration 14h 49m Onboard + 30m Additional time* |
Direct Options | Direct Options | Direct Options |
Live departures
South San Francisco, CA to San Diego, CA bus times
The table below shows live departures for South San Francisco, CA to San Diego, CA buses for today, Thursday, March 19. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
 | 3:50 PM South San Francisco, CA | 15h14 | 7:04 AM San Diego, CA | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets South San Francisco, CA to San Diego, CA by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Bus from South San Francisco, CA to San Diego, CA
USAUSA
Buses from South San Francisco, CA to San Diego, CA run on average 24 times per day, taking around 15h 18m. Cheap bus tickets for this journey start at $71 (€59) if you book in advance.
There are 2 buses per day. The earliest bus runs at 04:01, the last at 23:25. The fastest bus covers the 451 miles (727 km) distance in 15h 14m.
Distance 451 miles (727 km) |
Average bus duration 15h 18m |
Cheapest ticket price $71 (€59) |
Buses per day 24 |
Direct buses 2 |
Fastest bus 15h 14m |
First bus 04:01 |
Last bus 23:25 |
Cheapest month Mar |
Cheapest day Wed |
High season Jan - Mar |
Low season Jan - Mar |
Bus providers: SamTrans from South San Francisco, CA to San Diego, CAYou can travel by bus between South San Francisco, CA to San Diego, CA with SamTrans for as low as $71 (€59). When you search for schedules and tickets, Omio will show you the best journey
SamTrans
FAQs: Bus from South San Francisco, CA to San Diego, CA
Find answers to the most common questions about traveling from South San Francisco, CA to San Diego, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Diego, CA, this guide helps you travel smarter and with confidence.
- Balboa Park, a sprawling urban park with museums, gardens, and the San Diego Zoo
- USS Midway Museum, a historic naval aircraft carrier museum offering interactive exhibits and tours
- La Jolla Cove, a picturesque coastal area known for its stunning views and marine life
- Gaslamp Quarter, a lively historic district with Victorian architecture, dining, and entertainment options
- Coronado Beach, a beautiful sandy beach known for its gentle waves and iconic hotel.
- Explore the vibrant art scene at the Museum of Contemporary Art San Diego
- enjoy a harbor cruise for stunning views of the skyline and naval ships
- hike the scenic trails at Torrey Pines State Natural Reserve
- visit the Birch Aquarium to learn about marine life and ocean conservation
- experience the thrill of a whale watching tour off the coast.
popular bus stations
Popular bus stations from South San Francisco, CA to San Diego, CA
More options for your journey from South San Francisco, CA to San Diego, CA
Here are some other resources that might have the information you need
Most popular buses to and from San Diego, CA and South San Francisco, CA
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