The cheapest and fastest buses from Charlotte, NC to Knoxville, TN
Cheapest price
$124
Average price
$124
Fastest journey
9 h
Average duration
9 h
Buses per day
1
Distance
290 km
The best way to find a cheap bus ticket from Charlotte, NC to Knoxville, TN is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Charlotte, NC to Knoxville, TN will cost around $124 if you buy it on the day, but the cheapest tickets can be found for only $124.
It's difficult to get from Charlotte, NC to Knoxville, TN without transferring at least once.
· 12:50 PM9h00Charlotte, W 4th St (Greyhound Bus Station)9:50 PMKnoxville, Kirkwood Street, TN$1241One-way1 transfer
· 12:50 PM9h00Charlotte, W 4th St (Greyhound Bus Station)9:50 PMKnoxville, Kirkwood Street, TN$1241One-way1 transfer
Travel Information
Compare bus and flight for Charlotte, NC to Knoxville, TN
Omio recommends booking the flight as it is the most popular option from Charlotte, NC to Knoxville, TN among Omio's users. If you are prioritising price take the bus with prices starting from $74. For those with little time consider booking a flight which can get you there in 1h 17m. The ticket price range depends on the travel mode: a bus costs an average of $74, and a flight costs an average of $366.
Distance: 180 miles (290 km)
Compare bus with
| Bus | Most popular Flight | Driving |
|---|---|---|
$121 Average price Cheapest | $384 Average price | $15 Average price (fuel + tolls) |
9h 30m Average total duration 9h 0m Onboard + 30m Additional time* | 4h 17m Average total duration Fastest 1h 17m Onboard + 3h 0m Additional time* | 3h 58m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Charlotte, NC to Knoxville, TN:
A bus is $264 (€217) less than a flight for this route with tickets for a flight from Charlotte, NC to Knoxville, TN costing on average $384 (€317).
Other travel options to Knoxville, TN take longer:
Bus takes on average 9h 0m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
Charlotte, NC to Knoxville, TN Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 12:50PM | Arrival Time 09:50PM | Duration 9h00 | Departure days Everyday | Cheapest price $85 |
Live departures
Charlotte, NC to Knoxville, TN bus times
The table below shows live departures for Charlotte, NC to Knoxville, TN buses for today, Thursday, July 2. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
· | 12:50 PM Charlotte, W 4th St (Greyhound Bus Station) | 9h00 | 9:50 PM Knoxville, Kirkwood Street, TN | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Charlotte, NC to Knoxville, TN by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Jul 03
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Journey information
Overview: Bus from Charlotte, NC to Knoxville, TN
Buses from Charlotte, NC to Knoxville, TN run on average 1 times per day, taking around 9h 0m. Cheap bus tickets for this journey start at $74 (€61) if you book in advance.
The earliest bus runs at 08:55, the last at 19:40. The fastest bus covers the 180 miles (290 km) distance in 9h 0m.
Distance 180 miles (290 km) |
Average bus duration 9h 0m |
Cheapest ticket price $74 (€61) |
Buses per day 1 |
Fastest bus 9h 0m |
First bus 8:55 AM |
Last bus 7:40 PM |
Cheapest Month Apr |
Cheapest Day Sun |
High Season Oct - Dec |
Low Season Jul - Sep |
FAQs: Bus from Charlotte, NC to Knoxville, TN
Find answers to the most common questions about traveling from Charlotte, NC to Knoxville, TN by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Knoxville, TN, this guide helps you travel smarter and with confidence.

popular bus stations
Popular bus stations from Charlotte, NC to Knoxville, TN
Most Charlotte, NC to Knoxville, TN buses use the Charlotte, W 4th St (Greyhound Bus Station) to Knoxville, Kirkwood Street station pair. Use this guide to compare Charlotte, NC and Knoxville, TN bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Getting to Charlotte, W 4th St (Greyhound Bus Station) from Charlotte city centre
Getting to Charlotte, Freedom Drive (Planet Fitness) from Charlotte city centre
Getting to Knoxville, Kirkwood Street from Knoxville city centre
More options for your journey from Charlotte, NC to Knoxville, TN
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