- Recommended
East Tennessee History Center
Engaging museum on regional history with permanent and rotating exhibits covering people, places, and events from East Tennessee's past.
Cheapest price on Oct 02
$64
Average ticket price on Oct 02
$64
Fastest journey on Oct 02
9 h
Average journey duration on Oct 02
9 h
Buses on Oct 02
1
Distance
290 km
The best way to find a cheap bus ticket from Charlotte, NC to Knoxville, TN is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Charlotte, NC to Knoxville, TN will cost around $64 if you buy it on the day, but the cheapest tickets can be found for only $64.
It's difficult to get from Charlotte, NC to Knoxville, TN without transferring at least once.
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· Buses from Charlotte, NC to Knoxville, TN run on average 1 times per day, taking around 8h 30m. Cheap bus tickets for this journey start at $61 (€51) if you book in advance.
The earliest bus runs at 08:55, the last at 19:40. The fastest bus covers the 180 miles (290 km) distance in 8h 25m.
Distance 180 miles (290 km) |
Average bus duration 8h 30m |
Cheapest ticket price $61 (€51) |
Buses per day 1 |
Fastest bus 8h 25m |
First bus 8:55 AM |
Last bus 7:40 PM |
Cheapest Month Apr |
Cheapest Day Thu |
High Season Jul - Sep |
Low Season Jan - Mar |
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 12:50PM | Arrival Time 09:50PM | Duration 9h00 | Departure days Tue, Wed, Fri, Sat, Sun | Cheapest price $58 |
Operator Greyhound | Departure Time 12:55PM | Arrival Time 09:50PM | Duration 8h55 | Departure days Thu | Cheapest price $134 |
Operator Greyhound | Departure Time 05:50PM | Arrival Time 02:50AM | Duration 9h00 | Departure days Mon | Cheapest price $112 |
The table below shows live departures for Charlotte, NC to Knoxville, TN buses for today, Thursday, October 1. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
· | 12:55 PM Charlotte, W 4th St (Greyhound Bus Station) | 8h55 | 9:50 PM Knoxville, Kirkwood Street, TN | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Discover the best of Knoxville, TN — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Knoxville, TN trip today.
Engaging museum on regional history with permanent and rotating exhibits covering people, places, and events from East Tennessee's past.
University museum featuring changing exhibitions of American and international art in a modern gallery setting near campus.
Historic house museum preserving the home of artist Adelia Armstrong Lutz, with decorative arts, local history, and period rooms.
Lively pedestrian-friendly square lined with shops, events, and public seating. It is a central gathering place and a great base for exploring downtown.
Urban park from the 1982 World's Fair with lawns, walking paths, performance spaces, and easy access to the Sunsphere and museums.
Historic warehouse district with brick streets, galleries, murals, and nightlife. It blends railroad-era character with a creative local feel.
Smoky pulled pork barbecue is a regional staple in East Tennessee, usually hickory-smoked and served with slaw and sauce at local cookouts and barbecue joints.
Fried catfish is a longtime Tennessee favorite, coated in cornmeal and served with hush puppies or sides, especially popular in casual Southern eateries.
Biscuits with sausage gravy are a classic Southern breakfast in Knoxville, featuring flaky biscuits topped with rich peppery gravy made with pork drippings and milk.
Long-running neighborhood restaurant known for hearty Southern comfort food, pies, and a warm, traditional dining room.
Upscale Southern restaurant in Market Square known for shrimp and grits, steaks, and a polished downtown atmosphere.
Casual old-school barbecue spot serving hickory-smoked pork, ribs, and classic East Tennessee sides in a relaxed setting.
Moderate for U.S. city breaks: hotels and dining are reasonable, while car travel is common and public transit is limited for tourists.
Tip 18-20% at restaurants, 10-15% for taxis, and $1-2 per drink or coffee is appreciated at cafes.
Find answers to the most common questions about traveling from Charlotte, NC to Knoxville, TN by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Knoxville, TN, this guide helps you travel smarter and with confidence.

Most Charlotte, NC to Knoxville, TN buses use the Charlotte, W 4th St (Greyhound Bus Station) to Knoxville, Kirkwood Street station pair. Use this guide to compare Charlotte, NC and Knoxville, TN bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Charlotte, W 4th St (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Charlotte, W 4th St (Greyhound Bus Station). ATMs are available at Charlotte, W 4th St (Greyhound Bus Station).
Ticket office support is available at Charlotte, W 4th St (Greyhound Bus Station).
Available at Charlotte, W 4th St (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Charlotte, W 4th St (Greyhound Bus Station): The station is wheelchair accessible.
Knoxville, Kirkwood Street is 5 km from Knoxville city centre. Public transport options include:
Knoxville, Kirkwood Street has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Knoxville, Kirkwood Street. ATMs are available at Knoxville, Kirkwood Street.
Ticket office support is available at Knoxville, Kirkwood Street.
Available at Knoxville, Kirkwood Street: Parking, Taxis, WC.
Accessibility facilities are available at Knoxville, Kirkwood Street: Wheelchair accessible buses available.
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