4.9
4.6
Travel Information
Compare bus and flight for Orlando, FL to Knoxville, TN
Omio recommends booking the flight as it is the most popular option from Orlando, FL to Knoxville, TN among Omio's users. If you are prioritising price take the bus with prices starting from $101. For those with little time consider booking a flight which can get you there in 1h 36m. The ticket price range depends on the travel mode: a bus costs an average of $101, and a flight costs an average of $136.
Distance: 533 miles (859 km)
Compare bus with
| Bus | Most popular Flight | Driving |
|---|---|---|
$148 Average price Cheapest | $160 Average price | $15 Average price (fuel + tolls) |
24h 55m Average total duration 24h 25m Onboard + 30m Additional time* | 4h 36m Average total duration Fastest 1h 36m Onboard + 3h 0m Additional time* | 9h 47m Average total duration (door-to-door) |
 Most popular bus company |  Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Orlando, FL to Knoxville, TN:
A bus is $12 (€9) less than a flight for this route with tickets for a flight from Orlando, FL to Knoxville, TN costing on average $160 (€128).
Other travel options to Knoxville, TN take longer:
Bus takes on average 24h 25m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
Compare prices and tickets Orlando, FL to Knoxville, TN by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Orlando, FL to Knoxville, TN buses with Omio?
Why book with Omio vs FlixBus?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are bus and flight to ensure you get the best deal for traveling from Orlando, FL to Knoxville, TN.
Why book with Omio over Wanderu or Trainline?
- Multiple modes of transport: Omio allows you to compare travel options including bus and flight to find the ideal travel option from Orlando, FL to Knoxville, TN.
Journey information
Overview: Bus from Orlando, FL to Knoxville, TN
USAUSA
Buses from Orlando, FL to Knoxville, TN run on average 3 times per day, taking around 24h 25m. Cheap bus tickets for this journey start at $101 (€81) if you book in advance.
The earliest bus runs at 05:15, the last at 23:40. The fastest bus covers the 533 miles (859 km) distance in 23h 45m.
Distance 533 miles (859 km) |
Average bus duration 24h 25m |
Cheapest ticket price $101 (€81) |
Buses per day 3 |
Fastest bus 23h 45m |
First bus 5:15 AM |
Last bus 11:40 PM |
Cheapest Month Nov |
Cheapest Day Sat |
High Season Oct - Dec |
Low Season Jul - Sep |
Bus providers: FlixBus from Orlando, FL to Knoxville, TNYou can travel by bus between Orlando, FL to Knoxville, TN with FlixBus for as low as $101 (€81). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
FAQs: Bus from Orlando, FL to Knoxville, TN
Find answers to the most common questions about traveling from Orlando, FL to Knoxville, TN by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Knoxville, TN, this guide helps you travel smarter and with confidence.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Orlando, FL to Knoxville, TN
Most popular bus connections from Orlando, FL
More options for your journey from Orlando, FL to Knoxville, TN
Here are some other resources that might have the information you need
Most popular buses to and from Knoxville, TN and Orlando, FL
Most popular bus connections to Knoxville, TN
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