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Journey information
Overview: Bus from Orlando, FL to Knoxville, TN
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 533 miles (859 km) |
Average bus duration 24h 25m |
Buses per day 3 |
First bus 05:15 |
Last bus 22:55 |
Key Takeaways
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Bus providers: FlixBus from Orlando, FL to Knoxville, TNYou can travel by bus between Orlando, FL to Knoxville, TN with FlixBus. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
FlixBus frequency
3 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
FAQs: Bus from Orlando, FL to Knoxville, TN
Find answers to the most common questions about traveling from Orlando, FL to Knoxville, TN by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Knoxville, TN, this guide helps you travel smarter and with confidence.

Cheap bus tickets from Orlando, FL to Knoxville, TN can start from as little as $143 (€117) when you book in advance. The average bus ticket price for Orlando, FL to Knoxville, TN is $143 (€117); however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
On average the Orlando, FL to Knoxville, TN bus travel time is 17 h 5 min for the 533 mile (859 km) long trip, but the duration can vary if you travel on weekends and holidays.
The first bus from Orlando, FL to Knoxville, TN leaves at 5: 15AM. Plan your trip with the Journey Planner from Omio.
The last bus from Orlando, FL to Knoxville, TN leaves at 11: 45PM.
There are 4 buses a day from Orlando, FL to Knoxville, TN which require at least one change with FlixBus. Schedules can vary on holidays or weekends with fewer buses.
For the route from Orlando, FL to Knoxville, TN you can take a bus with FlixBus. Be sure to check out all possible bus providers that offer services to Knoxville, TN from Orlando, FL on Omio to compare what amenities they may have.
The cheapest month for a bus from Orlando, FL to Knoxville, TN is October.
You have options as you can travel between Orlando, FL and Knoxville, TN 2 different ways: bus or flight.
Yes, the following accessibility options are available when taking the bus from Orlando, FL to Knoxville, TN:
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Orlando, FL to Knoxville, TN for bus company FlixBus.
Yes, bikes are allowed on board the bus with bus company FlixBus.
Whether you can cancel your bus ticket from Orlando, FL to Knoxville, TN depends on the bus company:
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
To find the cheapest bus tickets for your trip from Orlando, FL to Knoxville, TN, follow these tips:
Start your search now and compare ticket prices to find the best deal!
Yes, there is food available to purchase on board the bus from Orlando, FL to Knoxville, TN.
Yes, the following luggage options are included when booking a bus ticket from Orlando, FL to Knoxville, TN:
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Orlando, FL to Knoxville, TN:
- FlixBus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Orlando, FL to Knoxville, TN. The following conditions apply:
- FlixBus
- Small pets in carriers allowed
- Guide dogs travel for free.
You can reserve your seat on the bus from Orlando, FL to Knoxville, TN with the following bus company: FlixBus
Yes, there are USB plugs on board the bus from Orlando, FL to Knoxville, TN with the following bus company: FlixBus.
Yes, there is Wifi on board the bus from Orlando, FL to Knoxville, TN with the following bus company: FlixBus.
popular bus stations
Popular bus stations from Orlando, FL to Knoxville, TN
Orlando
Knoxville
The major bus station for departures in Orlando is Orlando, The Florida Mall. Find all the information you need to know about services, amenities and connections at Orlando, The Florida Mall for your trip from Orlando to Knoxville.
Orlando, The Florida Mall
information
Orlando, N John Young Pkwy (Greyhound Bus Station)
information
The major bus station for arrivals in Knoxville is Knoxville, Kirkwood Street. Find all the information you need to know about services, amenities and connections at Knoxville, Kirkwood Street for your trip to Knoxville from Orlando.
Knoxville, Kirkwood Street
information
Most popular bus connections from Orlando, FL
More options for your journey from Orlando, FL to Knoxville, TN
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