Orlando, FL to Knoxville, TN bus with FlixBus

Fri, Jul 03
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2,000+ travel companies
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The cheapest and fastest buses from Orlando, FL to Knoxville, TN

Showing times and prices for Jul 03

Cheapest price

$181

Average price

$196

Fastest journey

15 h 50 m

Average duration

23 h 15 m

Buses per day

3

Distance

859 km

Cheap tickets

The best way to find a cheap bus ticket from Orlando, FL to Knoxville, TN is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Orlando, FL to Knoxville, TN will cost around $196 if you buy it on the day, but the cheapest tickets can be found for only $181.

Fast buses

It's difficult to get from Orlando, FL to Knoxville, TN without transferring at least once.

  • FlixBusFlixBus · FlixBus+Greyhound
    10:55 PM23h45
    Orlando, N John Young Pkwy (Greyhound Bus Station)
    10:40 PMKnoxville, Kirkwood Street, TN
    $1811One-way
    2 transfers
  • FlixBusFlixBus+Greyhound
    6:00 AM15h50
    Orlando, N John Young Pkwy (Greyhound Bus Station)
    9:50 PMKnoxville, Kirkwood Street, TN
    $2031One-way
    1 transfer
  • FlixBusFlixBus+Greyhound ·
    3:40 PM30h10
    Orlando, N John Young Pkwy (Greyhound Bus Station)
    9:50 PMKnoxville, Kirkwood Street, TN
    $2051One-way
    2 transfers

Travel Information

Compare bus and flight for Orlando, FL to Knoxville, TN

Omio recommends booking the flight as it is the most popular option from Orlando, FL to Knoxville, TN among Omio's users. If you are prioritising price take the bus with prices starting from $98. For those with little time consider booking a flight which can get you there in 1h 36m. The ticket price range depends on the travel mode: a bus costs an average of $98, and a flight costs an average of $132.

Distance: 533 miles (859 km)

Compare bus with

Bus
Most popular
Flight
Driving

$144

Average price

Cheapest

$155

Average price

$14

Average price

(fuel + tolls)

24h 55m

Average total duration

24h 25m

Onboard

+

30m

Additional time*

4h 36m

Average total duration

Fastest

1h 36m

Onboard

+

3h 0m

Additional time*

9h 47m

Average total duration

(door-to-door)

FlixBus

Most popular bus company

Allegiant Air

Most popular airline

Your own car or car rental

Direct Options

Direct Options

Direct Options

The cheapest way to travel from Orlando, FL to Knoxville, TN is a bus with an average price of $144 (€119).

This is compared to other travel options from Orlando, FL to Knoxville, TN:

A bus is $11 (€9) less than a flight for this route with tickets for a flight from Orlando, FL to Knoxville, TN costing on average $155 (€128).

The fastest way to travel from Orlando, FL to Knoxville, TN is by flight with an average journey time of 1h 36m.

Other travel options to Knoxville, TN take longer:

Bus takes on average 24h 25m.

It's helpful to compare your options as there are 2 ways to travel between Orlando, FL and Knoxville, TN including taking a bus and flight.
We recommend using the flight as it is the most popular way to get from Orlando, FL to Knoxville, TN among Omio's users.
Take the bus. On this route, it's both cheaper and quicker than driving.

You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.

Direct coaches are operated by {directProviders}.

Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.

Orlando, FL to Knoxville, TN Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
FlixBus
Departure Time
06:00AM
Arrival Time
09:50PM
Duration
15h50
Departure days
Everyday
Cheapest price
$144
Operator
FlixBus
Departure Time
03:40PM
Arrival Time
09:50PM
Duration
30h10
Departure days
Mon, Wed, Thu, Fri, Sat, Sun
Cheapest price
$148
Operator
FlixBus
Departure Time
10:55PM
Arrival Time
10:40PM
Duration
23h45
Departure days
Everyday
Cheapest price
$146

Live departures

Orlando, FL to Knoxville, TN bus times

The table below shows live departures for Orlando, FL to Knoxville, TN buses for today, Thursday, July 2. You can also manually refresh the results below to see updated bus journeys.

Last updated at
ProviderDepartsDurationArrivesTransfers
Tickets
FlixBusFlixBus+Greyhound6:00 AM Orlando, N John Young Pkwy (Greyhound Bus Station)
15h50
9:50 PM Knoxville, Kirkwood Street, TN1 transfer
FlixBusFlixBus+Greyhound · 3:40 PM Orlando, N John Young Pkwy (Greyhound Bus Station)
30h10
9:50 PM Knoxville, Kirkwood Street, TN2 transfers
FlixBusFlixBus+Greyhound · 10:55 PM Orlando, N John Young Pkwy (Greyhound Bus Station)
23h45
10:40 PM Knoxville, Kirkwood Street, TN2 transfers

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Orlando, FL to Knoxville, TN by bus or flight

Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

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Why should you book Orlando, FL to Knoxville, TN buses with Omio?

FlixBus operates all buses services from Orlando, FL to Knoxville, TN.
Omio is an official ticket reseller for all your travel options from Orlando, FL to Knoxville, TN.

Why book with Omio vs FlixBus?

  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are bus and flight to ensure you get the best deal for traveling from Orlando, FL to Knoxville, TN.

Why book with Omio over Wanderu or Trainline?

  • Multiple modes of transport: Omio allows you to compare travel options including bus and flight to find the ideal travel option from Orlando, FL to Knoxville, TN.

Journey information

Overview: Bus from Orlando, FL to Knoxville, TN

USAUSA
USAUSA
Icon of bus

Buses from Orlando, FL to Knoxville, TN run on average 3 times per day, taking around 24h 25m. Cheap bus tickets for this journey start at $98 (€81) if you book in advance.

The earliest bus runs at 05:15, the last at 23:40. The fastest bus covers the 533 miles (859 km) distance in 23h 45m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
533 miles (859 km)
Average bus duration
24h 25m
Cheapest ticket price
$98 (€81)
Buses per day
3
Fastest bus
23h 45m
First bus
5:15 AM
Last bus
11:40 PM
Cheapest Month
Nov
Cheapest Day
Sat
High Season
Oct - Dec
Low Season
Jul - Sep
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Bus providers: FlixBus from Orlando, FL to Knoxville, TNYou can travel by bus between Orlando, FL to Knoxville, TN with FlixBus for as low as $98 (€81). When you search for schedules and tickets, Omio will show you the best journey

FlixBus

About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
23h 45m
Cheapest Price
$98 (€81)
FlixBus frequency
3 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.

FAQs: Bus from Orlando, FL to Knoxville, TN

Find answers to the most common questions about traveling from Orlando, FL to Knoxville, TN by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Knoxville, TN, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Orlando, FL to Knoxville, TN can start from as little as $98 (€81) when you book in advance. The average bus ticket price for Orlando, FL to Knoxville, TN is $144 (€119) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Orlando, FL to Knoxville, TN is 23h 45m to travel the 533 miles (859 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Orlando, FL to Knoxville, TN leaves at 5:15 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Orlando, FL to Knoxville, TN leaves at 11:40 PM.
There are 3 buses a day from Orlando, FL to Knoxville, TN which require at least one change with FlixBus. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Orlando, FL to Knoxville, TN, you can count on FlixBus for the best way to get you to Knoxville, TN. You can also check all possible bus companies who offer a service between Orlando, FL and Knoxville, TN and compare the amenities they offer before buying a bus ticket.
A trip to Knoxville, TN from Orlando, FL is worth doing but not as a day trip with a journey time of 23h 45m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Orlando, FL to Knoxville, TN is November.
It's helpful to compare your options as there are 2 ways to travel between Orlando, FL and Knoxville, TN including taking a bus and flight.
Yes, the following accessibility options are available when taking the bus from Orlando, FL to Knoxville, TN:
  • FlixBus
    • Assistance
    • Priority boarding
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Orlando, FL to Knoxville, TN for bus company FlixBus.
Whether you can cancel your bus ticket from Orlando, FL to Knoxville, TN depends on the bus companies:
  • FlixBus
    • You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Orlando, FL to Knoxville, TN.
Yes, the following luggage options are included when booking a bus ticket from Orlando, FL to Knoxville, TN:
  • FlixBus
    • One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Orlando, FL to Knoxville, TN:
  • FlixBus
    • Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Orlando, FL to Knoxville, TN. The following conditions apply:
  • FlixBus
    • Small pets in carriers allowed
    • guide dogs travel for free.
You can reserve your seat on the bus from Orlando, FL to Knoxville, TN with the following bus company: FlixBus
Yes, there are USB plugs on board the bus from Orlando, FL to Knoxville, TN with the following bus company: FlixBus.
Yes, there is Wifi on board the bus from Orlando, FL to Knoxville, TN with the following bus company: FlixBus.
Since neither Orlando, FL nor Knoxville, TN are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the flight as it is the most popular way to get from Orlando, FL to Knoxville, TN among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Knoxville, TN, travelers should be cautious of pickpocketing and vehicle break-ins, especially in crowded areas and parking lots. Avoid accepting unsolicited offers for transportation or tours, as unlicensed operators may overcharge or provide unsafe services. It's also advisable to stay in well-lit areas at night and be aware of local traffic patterns when using ride-share or public transportation to ensure safety.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular bus stations

Popular bus stations from Orlando, FL to Knoxville, TN

Most Orlando, FL to Knoxville, TN buses use the Orlando, N John Young Pkwy (Greyhound Bus Station) to Knoxville, Kirkwood Street station pair. Use this guide to compare Orlando, FL and Knoxville, TN bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.

Departure bus stations in Orlando
Arrival bus stations in Knoxville
Orlando, N John Young Pkwy (Greyhound Bus Station)
City-centre transport

Getting to Orlando, N John Young Pkwy (Greyhound Bus Station) from Orlando city centre

Bus125 · 40m · $2 · every ~6 min
125 · 41m · $2 · every ~6 min
Orlando, The Florida MallOrlando Florida Mall Ave,Florida Mall Ave 1632,32809
City-centre transport

Getting to Orlando, The Florida Mall from Orlando city centre

Bus42 · 26m · $2 · every ~5 min

More options for your journey from Orlando, FL to Knoxville, TN

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HomeBusesBuses in USAOrlando, FL to Knoxville, TN bus

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