- Recommended
East Tennessee History Center
Engaging museum on regional history with permanent and rotating exhibits covering people, places, and events from East Tennessee's past.
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The cheapest and fastest buses from Orlando, FL to Knoxville, TN
Showing times, prices and bookable tickets for Oct 02
Cheapest price on Oct 02
$92
Average ticket price on Oct 02
$100
Fastest journey on Oct 02
15 h 50 m
Average journey duration on Oct 02
23 h 15 m
Buses on Oct 02
3
Distance
859 km
Cheap tickets
The best way to find a cheap bus ticket from Orlando, FL to Knoxville, TN is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Orlando, FL to Knoxville, TN will cost around $100 if you buy it on the day, but the cheapest tickets can be found for only $92.
Fast buses
It's difficult to get from Orlando, FL to Knoxville, TN without transferring at least once.
FlixBus · FlixBus+
10:55 PM23h45Orlando, N John Young Pkwy (Greyhound Bus Station)10:40 PMKnoxville, Kirkwood Street, TN$921One-way2 transfers- FlixBus+6:00 AM15h50Orlando, N John Young Pkwy (Greyhound Bus Station)9:50 PMKnoxville, Kirkwood Street, TN$931One-way1 transfer
- FlixBus+ · 3:40 PM30h10Orlando, N John Young Pkwy (Greyhound Bus Station)9:50 PMKnoxville, Kirkwood Street, TN$1151One-way2 transfers
- FlixBus+6:00 AM15h50Orlando, N John Young Pkwy (Greyhound Bus Station)9:50 PMKnoxville, Kirkwood Street, TN$931One-way1 transfer
- FlixBus · FlixBus+10:55 PM23h45Orlando, N John Young Pkwy (Greyhound Bus Station)10:40 PMKnoxville, Kirkwood Street, TN$921One-way2 transfers
- FlixBus+ · 3:40 PM30h10Orlando, N John Young Pkwy (Greyhound Bus Station)9:50 PMKnoxville, Kirkwood Street, TN$1151One-way2 transfers
Journey information
Overview: Bus from Orlando, FL to Knoxville, TN
USAUSA
Buses from Orlando, FL to Knoxville, TN run on average 3 times per day, taking around 18h 14m. Cheap bus tickets for this journey start at $99 (€82) if you book in advance.
The earliest bus runs at 05:15, the last at 23:40. The fastest bus covers the 533 miles (859 km) distance in 13h 30m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 533 miles (859 km) |
Average bus duration 18h 14m |
Cheapest ticket price $99 (€82) |
Buses per day 3 |
Fastest bus 13h 30m |
First bus 5:15 AM |
Last bus 11:40 PM |
Cheapest Month Nov |
Cheapest Day Sat |
High Season Jul - Sep |
Low Season Jan - Mar |
Best time to book 35 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Orlando, FL to Knoxville, TN Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 06:00AM | Arrival Time 09:50PM | Duration 15h50 | Departure days Everyday | Cheapest price $93 |
Operator FlixBus | Departure Time 03:40PM | Arrival Time 09:50PM | Duration 30h10 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $109 |
Operator FlixBus | Departure Time 10:55PM | Arrival Time 10:30PM | Duration 23h35 | Departure days Everyday | Cheapest price $92 |
Live departures
Orlando, FL to Knoxville, TN bus times
The table below shows live departures for Orlando, FL to Knoxville, TN buses for today, Thursday, October 1. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| FlixBus+ · | 3:40 PM Orlando, N John Young Pkwy (Greyhound Bus Station) | 30h10 | 9:50 PM Knoxville, Kirkwood Street, TN | 2 transfers | |
| FlixBus+ · | 10:55 PM Orlando, N John Young Pkwy (Greyhound Bus Station) | 23h35 | 10:30 PM Knoxville, Kirkwood Street, TN | 2 transfers | |
| Friday, October 2 | |||||
| FlixBus+ | 6:00 AM Orlando, N John Young Pkwy (Greyhound Bus Station) | 15h50 | 9:50 PM Knoxville, Kirkwood Street, TN | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Why should you book Orlando, FL to Knoxville, TN buses with Omio?
Greyhound as well as FlixBus offer buses services from Orlando, FL to Knoxville, TN.
Omio is an official ticket reseller for all your travel options from Orlando, FL to Knoxville, TN.
Why book with Omio vs Greyhound?
- Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of FlixBus to find the best option for your trip from Orlando, FL to Knoxville, TN.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus and flight to ensure you get the best deal for traveling from Orlando, FL to Knoxville, TN.
Why book with Omio over Wanderu or Trainline?
- Compare with other providers: On Omio, you can also compare tickets for the likes of FlixBus to find the best option for your trip from Orlando, FL to Knoxville, TN.
- Multiple modes of transport: Omio allows you to compare travel options including bus and flight to find the ideal travel option from Orlando, FL to Knoxville, TN.
Bus providers: FlixBus, Greyhound from Orlando, FL to Knoxville, TNYou can travel by bus between Orlando, FL to Knoxville, TN with FlixBus, Greyhound for as low as $99 (€82). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average FlixBus Duration
13h 30m
Cheapest FlixBus Price
$99 (€82)
FlixBus frequency
3 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Greyhound Duration
22h 10m
Cheapest Greyhound Price
$220 (€183)
Greyhound frequency
1 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Complete guide to Knoxville, TN
Things to do in Knoxville, TN
Discover the best of Knoxville, TN — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Knoxville, TN trip today.
- Recommended
McClung Museum of Natural History and Culture
University museum featuring changing exhibitions of American and international art in a modern gallery setting near campus.
- Recommended
Mabry-Hazen House
Historic house museum preserving the home of artist Adelia Armstrong Lutz, with decorative arts, local history, and period rooms.
- Must visit
Market Square
Lively pedestrian-friendly square lined with shops, events, and public seating. It is a central gathering place and a great base for exploring downtown.
- Must visit
World's Fair Park
Urban park from the 1982 World's Fair with lawns, walking paths, performance spaces, and easy access to the Sunsphere and museums.
- Recommended
Old City
Historic warehouse district with brick streets, galleries, murals, and nightlife. It blends railroad-era character with a creative local feel.
Pulled Pork Barbecue
Smoky pulled pork barbecue is a regional staple in East Tennessee, usually hickory-smoked and served with slaw and sauce at local cookouts and barbecue joints.
Fried Catfish
Fried catfish is a longtime Tennessee favorite, coated in cornmeal and served with hush puppies or sides, especially popular in casual Southern eateries.
Biscuits And Sausage Gravy
Biscuits with sausage gravy are a classic Southern breakfast in Knoxville, featuring flaky biscuits topped with rich peppery gravy made with pork drippings and milk.
Litton's Market Restaurant
Long-running neighborhood restaurant known for hearty Southern comfort food, pies, and a warm, traditional dining room.
Stock & Barrel
Upscale Southern restaurant in Market Square known for shrimp and grits, steaks, and a polished downtown atmosphere.
Sweet P's Barbeque And Soul House
Casual old-school barbecue spot serving hickory-smoked pork, ribs, and classic East Tennessee sides in a relaxed setting.
$ US dollar
Moderate for U.S. city breaks: hotels and dining are reasonable, while car travel is common and public transit is limited for tourists.
Average meal costs
- Budget
- $10-15 for fast food or a casual lunch.
- Mid-range
- $18-35 per person for a restaurant meal.
- Fine dining
- $50+ per person for upscale dining.
- Coffee
- $3-5 for a coffee or cappuccino.
Tipping culture
Tip 18-20% at restaurants, 10-15% for taxis, and $1-2 per drink or coffee is appreciated at cafes.
FAQs: Bus from Orlando, FL to Knoxville, TN
Find answers to the most common questions about traveling from Orlando, FL to Knoxville, TN by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Knoxville, TN, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Orlando, FL to Knoxville, TN can start from as little as $99 (€82) when you book in advance. The average bus ticket price for Orlando, FL to Knoxville, TN is $155 (€129) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Orlando, FL to Knoxville, TN is 13h 30m to travel the 533 miles (859 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Orlando, FL to Knoxville, TN leaves at 5:15 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Orlando, FL to Knoxville, TN leaves at 11:40 PM.
There are 3 buses a day from Orlando, FL to Knoxville, TN which require at least one change with Greyhound, FlixBus. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Orlando, FL to Knoxville, TN, you can count on Greyhound, FlixBus for the best way to get you to Knoxville, TN. You can also check all possible bus companies who offer a service between Orlando, FL and Knoxville, TN and compare the amenities they offer before buying a bus ticket.
When departing from Orlando, FL , you have various bus station options to start your journey from including Orlando, N John Young Pkwy (Greyhound Bus Station), Orlando, The Florida Mall, FL . When arriving in Knoxville, TN , you can end your journey in bus stations like Knoxville, Kirkwood Street, TN .Passengers board the bus most frequently from Orlando, N John Young Pkwy (Greyhound Bus Station), which is located around 1 miles (3 km) away from the city centre, and they get off the bus at Knoxville, Kirkwood Street, TN, located 5 away from the city centre.
It's helpful to compare your options as there are 2 ways to travel between Orlando, FL and Knoxville, TN including taking a bus and flight.
Yes, the following accessibility options are available when taking the bus from Orlando, FL to Knoxville, TN:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Orlando, FL to Knoxville, TN for bus company Greyhound, FlixBus.
Whether you can cancel your bus ticket from Orlando, FL to Knoxville, TN depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company Greyhound, FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Orlando, FL to Knoxville, TN.
Yes, the following luggage options are included when booking a bus ticket from Orlando, FL to Knoxville, TN:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Orlando, FL to Knoxville, TN:
- Greyhound
- $15 per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Orlando, FL to Knoxville, TN. The following conditions apply:
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
You can reserve your seat on the bus from Orlando, FL to Knoxville, TN with the following bus company: Greyhound, FlixBus
Yes, there are USB plugs on board the bus from Orlando, FL to Knoxville, TN with the following bus company: Greyhound, FlixBus.
Yes, there is Wifi on board the bus from Orlando, FL to Knoxville, TN with the following bus company: Greyhound, FlixBus.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Knoxville, TN, travelers should be cautious of pickpocketing and vehicle break-ins, especially in crowded areas and parking lots. Avoid accepting unsolicited offers for transportation or tours, as unlicensed operators may overcharge or provide unsafe services. It's also advisable to stay in well-lit areas at night and be aware of local traffic patterns when using ride-share or public transportation to ensure safety.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Orlando, FL to Knoxville, TN
Most Orlando, FL to Knoxville, TN buses use the Orlando, N John Young Pkwy (Greyhound Bus Station) to Knoxville, Kirkwood Street station pair. Use this guide to compare Orlando, FL and Knoxville, TN bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Orlando
Arrival bus stations in Knoxville
Which Orlando, FL station do buses to Knoxville, TN leave from?
Buses from Orlando, FL to Knoxville, TN leave from Orlando, N John Young Pkwy (Greyhound Bus Station). The station is 1 miles (3 km) from Orlando, FL city centre at 555 John Young Pkwy, Orlando, FL 32805, USA.
Orlando, N John Young Pkwy (Greyhound Bus Station)555 John Young Pkwy, Orlando, FL 32805, USA
City-centre transport
Getting to Orlando, N John Young Pkwy (Greyhound Bus Station) from Orlando city centre
Orlando, N John Young Pkwy (Greyhound Bus Station) is 3 km from Orlando city centre. Public transport options include:
Bus125 · 40m · $2 · every ~6 min
125 · 41m · $2 · every ~6 min
Orlando, N John Young Pkwy (Greyhound Bus Station) bus station facilities and services
Orlando, N John Young Pkwy (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Orlando, N John Young Pkwy (Greyhound Bus Station). ATMs are available at Orlando, N John Young Pkwy (Greyhound Bus Station).
Tickets and information
Ticket office support is available at Orlando, N John Young Pkwy (Greyhound Bus Station).
Parking, taxis and toilets
Available at Orlando, N John Young Pkwy (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Orlando, N John Young Pkwy (Greyhound Bus Station): The station is accessible for individuals with disabilities.
Orlando, The Florida MallOrlando Florida Mall Ave,Florida Mall Ave 1632,32809
City-centre transport
Getting to Orlando, The Florida Mall from Orlando city centre
Bus42 · 26m · $2 · every ~5 min
Which Knoxville, TN station do buses from Orlando, FL arrive at?
Buses from Orlando, FL to Knoxville, TN arrive at Knoxville, Kirkwood Street. Knoxville, Kirkwood Street is 3 miles (6 km) from Knoxville, TN city centre.
Knoxville, Kirkwood StreetKirkwood St, Knoxville, TN 37914, USA
City-centre transport
Getting to Knoxville, Kirkwood Street from Knoxville city centre
Knoxville, Kirkwood Street is 5 km from Knoxville city centre. Public transport options include:
Bus31, 33 · 20m · $2 · every ~6 min
Knoxville, Kirkwood Street bus station facilities and services
Knoxville, Kirkwood Street has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Knoxville, Kirkwood Street. ATMs are available at Knoxville, Kirkwood Street.
Tickets and information
Ticket office support is available at Knoxville, Kirkwood Street.
Parking, taxis and toilets
Available at Knoxville, Kirkwood Street: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Knoxville, Kirkwood Street: Wheelchair accessible buses available.
Most popular bus connections from Orlando, FL
More options for your journey from Orlando, FL to Knoxville, TN
Here are some other resources that might have the information you need
Most popular buses to and from Knoxville, TN and Orlando, FL
Most popular bus connections to Knoxville, TN
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