San Antonio, TX to Knoxville, TN bus

Thu, May 14
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Alsa
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Rede Expressos
Costa Verde
2,000+ travel companies
FlixBus
Alsa
BlaBlaCar Bus
Rede Expressos
Costa Verde
2,000+ travel companies
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The cheapest and fastest buses from San Antonio, TX to Knoxville, TN

Showing times and prices for May 15

Cheapest price

$325

Average price

$325

Fastest journey

1 d 25 m

Average duration

1 d 25 m

Buses per day

1

Distance

1543 km

Cheap tickets

The best way to find a cheap bus ticket from San Antonio, TX to Knoxville, TN is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from San Antonio, TX to Knoxville, TN will cost around $325 if you buy it on the day, but the cheapest tickets can be found for only $325.

Fast buses

Of the 1 buses that leave San Antonio, TX for Knoxville, TN on Fri, May 15, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.

On Fri, May 15 the direct buses cover the 1543 km distance in an average of 1 d 25 m but if you time it right, some buses will get you there in just 1 d 25 m .

On Fri, May 15 the slowest buses will take 1 d 25 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

  • Greyhound
    3:15 AM24h25
    San Antonio, TX
    3:40 AMKnoxville, TN
    $3251One-way
    0 transfers

Travel Information

Compare bus and flight for San Antonio, TX to Knoxville, TN

Omio recommends booking the flight as it is the most popular option from San Antonio, TX to Knoxville, TN among Omio's users. If you are prioritising price take the bus with prices starting from $203. For those with little time consider booking a flight which can get you there in 4h 53m. The ticket price range depends on the travel mode: a bus costs an average of $203, and a flight costs an average of $318.

Distance: 958 miles (1543 km)

Compare bus with

Bus
Most popular
Flight
Driving

$264

Average price

Cheapest

$323

Average price

$16

Average price

(fuel + tolls)

24h 35m

Average total duration

24h 5m

Onboard

+

30m

Additional time*

7h 53m

Average total duration

Fastest

4h 53m

Onboard

+

3h 0m

Additional time*

16h 15m

Average total duration

(door-to-door)

Direct Options

Direct Options

Direct Options

The cheapest way to travel from San Antonio, TX to Knoxville, TN is a bus with an average price of $264 (€212).

This is compared to other travel options from San Antonio, TX to Knoxville, TN:

A bus is $59 (€47) less than a flight for this route with tickets for a flight from San Antonio, TX to Knoxville, TN costing on average $323 (€259).

The fastest way to travel from San Antonio, TX to Knoxville, TN is by flight with an average journey time of 4h 53m.

Other travel options to Knoxville, TN take longer:

Bus takes on average 24h 5m.

It's helpful to compare your options as there are 2 ways to travel between San Antonio, TX and Knoxville, TN including taking a bus and flight.
Take the bus. On this route, it's both cheaper and quicker than driving.

You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.

Direct coaches are operated by {directProviders}.

Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.

San Antonio, TX to Knoxville, TN Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
Greyhound
Departure Time
01:30PM
Arrival Time
09:50PM
Duration
31h20
Departure days
Wed
Cheapest price
$255
Operator
Greyhound
Departure Time
09:00PM
Arrival Time
10:40PM
Duration
24h40
Departure days
Wed
Cheapest price
$257

Live departures

San Antonio, TX to Knoxville, TN bus times

The table below shows live departures for San Antonio, TX to Knoxville, TN buses for today, Wednesday, May 13. You can also manually refresh the results below to see updated bus journeys.

Last updated at
ProviderDepartsDurationArrivesTransfers
Tickets
Greyhound · +Valley Transit9:00 PM San Antonio, N St Mary's St (Greyhound), TX
24h40
10:40 PM Knoxville, Kirkwood Street, TN2 transfers
Thursday, May 14
Greyhound3:15 AM San Antonio, TX
24h25
3:40 AM Knoxville, TN0 transfersDirect

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets San Antonio, TX to Knoxville, TN by bus or flight

Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Thu
May 14
Fri
May 15
Sat
May 16
Sun
May 17
Mon
May 18
Tue
May 19
Wed
May 20

Journey information

Overview: Bus from San Antonio, TX to Knoxville, TN

USAUSA
USAUSA
Icon of bus

Buses from San Antonio, TX to Knoxville, TN run on average 3 times per day, taking around 24h 5m. Cheap bus tickets for this journey start at $203 (€162) if you book in advance.

The earliest bus runs at 13:30, the last at 21:15. The fastest bus covers the 958 miles (1543 km) distance in 23h 45m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
958 miles (1543 km)
Average bus duration
24h 5m
Cheapest ticket price
$203 (€162)
Buses per day
3
Fastest bus
23h 45m
First bus
1:30 PM
Last bus
9:15 PM
Cheapest Month
Jun
Cheapest Day
Sat
High Season
Apr - Jun
Low Season
Jan - Mar
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

FAQs: Bus from San Antonio, TX to Knoxville, TN

Find answers to the most common questions about traveling from San Antonio, TX to Knoxville, TN by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Knoxville, TN, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from San Antonio, TX to Knoxville, TN can start from as little as $203 (€162) when you book in advance. The average bus ticket price for San Antonio, TX to Knoxville, TN is $264 (€212) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from San Antonio, TX to Knoxville, TN is 23h 45m to travel the 958 miles (1543 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from San Antonio, TX to Knoxville, TN leaves at 1:30 PM. Plan your trip with the Journey Planner from Omio.
The latest bus from San Antonio, TX to Knoxville, TN leaves at 9:15 PM.
A trip to Knoxville, TN from San Antonio, TX is worth doing but not as a day trip with a journey time of 23h 45m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from San Antonio, TX to Knoxville, TN is June.
It's helpful to compare your options as there are 2 ways to travel between San Antonio, TX and Knoxville, TN including taking a bus and flight.
No, the bus from San Antonio, TX to Knoxville, TN has no accessibility options.
No, there are no bathrooms on board the bus from San Antonio, TX to Knoxville, TN.
No, bikes are not allowed on board the bus from San Antonio, TX to Knoxville, TN.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
No, there is no food available to purchase on board the bus from San Antonio, TX to Knoxville, TN.
No, luggage for the bus from San Antonio, TX to Knoxville, TN needs to be booked in addition.
No, there are no additional luggage options for the bus from San Antonio, TX to Knoxville, TN.
Unfortunately, pets are not allowed on the bus from San Antonio, TX to Knoxville, TN.
No, there are no USB plugs on board the bus from San Antonio, TX to Knoxville, TN.
No, there is no WiFi on board the bus from San Antonio, TX to Knoxville, TN.
Since neither San Antonio, TX nor Knoxville, TN are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Knoxville, TN, travelers should be cautious of pickpocketing and vehicle break-ins, especially in crowded areas and parking lots. Avoid accepting unsolicited offers for transportation or tours, as unlicensed operators may overcharge or provide unsafe services. It's also advisable to stay in well-lit areas at night and be aware of local traffic patterns when using ride-share or public transportation to ensure safety.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular bus stations

Popular bus stations from San Antonio, TX to Knoxville, TN

San Antonio
Knoxville
The major bus station for departures in San Antonio is San Antonio, N St Mary's St (Greyhound). Find all the information you need to know about services, amenities and connections at San Antonio, N St Mary's St (Greyhound) for your trip from San Antonio to Knoxville.
San Antonio, N St Mary's St (Greyhound)
information
San Antonio, Avenue A / Pearl Pkwy
information

More options for your journey from San Antonio, TX to Knoxville, TN

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