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Travel Information
Compare bus and flight for San Antonio, TX to Knoxville, TN
Omio recommends booking the flight as it is the most popular option from San Antonio, TX to Knoxville, TN among Omio's users. If you are prioritising price take the bus with prices starting from $130. For those with little time consider booking a flight which can get you there in 4h 15m. The ticket price range depends on the travel mode: a bus costs an average of $130, and a flight costs an average of $448.
Distance: 958 miles (1543 km)
Compare bus with
| Bus | Most popular Flight | Driving |
|---|---|---|
$130 Average price Cheapest | $448 Average price | $16 Average price (fuel + tolls) |
25h 10m Average total duration 24h 40m Onboard + 30m Additional time* | 7h 15m Average total duration Fastest 4h 15m Onboard + 3h 0m Additional time* | 16h 15m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from San Antonio, TX to Knoxville, TN:
A bus is $318 (€260) less than a flight for this route with tickets for a flight from San Antonio, TX to Knoxville, TN costing on average $448 (€367).
Other travel options to Knoxville, TN take longer:
Bus takes on average 24h 40m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
San Antonio, TX to Knoxville, TN Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 02:55AM | Arrival Time 02:40AM | Duration 23h45 | Departure days Sat | Cheapest price $199 |
Operator Greyhound | Departure Time 03:15AM | Arrival Time 03:40AM | Duration 24h25 | Departure days Fri | Cheapest price $319 |
Compare prices and tickets San Antonio, TX to Knoxville, TN by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Bus from San Antonio, TX to Knoxville, TN
USAUSA
Buses from San Antonio, TX to Knoxville, TN run on average 3 times per day, taking around 24h 40m. Cheap bus tickets for this journey start at $130 (€106) if you book in advance.
The earliest bus runs at 13:30, the last at 21:15. The fastest bus covers the 958 miles (1543 km) distance in 24h 40m.
Distance 958 miles (1543 km) |
Average bus duration 24h 40m |
Cheapest ticket price $130 (€106) |
Buses per day 3 |
Fastest bus 24h 40m |
First bus 1:30 PM |
Last bus 9:15 PM |
Cheapest Month Apr |
Cheapest Day Fri |
High Season Apr - Jun |
Low Season Jan - Mar |
FAQs: Bus from San Antonio, TX to Knoxville, TN
Find answers to the most common questions about traveling from San Antonio, TX to Knoxville, TN by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Knoxville, TN, this guide helps you travel smarter and with confidence.
popular bus stations
Popular bus stations from San Antonio, TX to Knoxville, TN
Most San Antonio, TX to Knoxville, TN buses use the San Antonio, N St Mary's St (Greyhound) to Knoxville, Kirkwood Street station pair. Use this guide to compare San Antonio, TX and Knoxville, TN bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Which San Antonio, TX station do buses to Knoxville, TN leave from?
Getting to San Antonio, N St Mary's St (Greyhound) from San Antonio city centre
San Antonio, N St Mary's St (Greyhound) bus station facilities and services
San Antonio, N St Mary's St (Greyhound) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at San Antonio, N St Mary's St (Greyhound). ATMs are available at San Antonio, N St Mary's St (Greyhound).
Tickets and information
Ticket office support is available at San Antonio, N St Mary's St (Greyhound).
Parking, taxis and toilets
Available at San Antonio, N St Mary's St (Greyhound): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at San Antonio, N St Mary's St (Greyhound): Limited accessibility features.
Getting to San Antonio, Avenue A / Pearl Pkwy from San Antonio city centre
San Antonio, Avenue A / Pearl Pkwy is 2 km from San Antonio city centre. Public transport options include:
San Antonio, Avenue A / Pearl Pkwy bus station facilities and services
San Antonio, Avenue A / Pearl Pkwy has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Nearby Pearl Brewery offers dining options.
Wi-Fi and ATMs
Wi-Fi is available at San Antonio, Avenue A / Pearl Pkwy. ATMs are available at San Antonio, Avenue A / Pearl Pkwy.
Tickets and information
Ticket office support is available at San Antonio, Avenue A / Pearl Pkwy.
Parking, taxis and toilets
Available at San Antonio, Avenue A / Pearl Pkwy: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at San Antonio, Avenue A / Pearl Pkwy: Accessible to wheelchair users.
Which Knoxville, TN station do buses from San Antonio, TX arrive at?
Getting to Knoxville, Kirkwood Street from Knoxville city centre
Knoxville, Kirkwood Street is 5 km from Knoxville city centre. Public transport options include:
Knoxville, Kirkwood Street bus station facilities and services
Knoxville, Kirkwood Street has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Knoxville, Kirkwood Street. ATMs are available at Knoxville, Kirkwood Street.
Tickets and information
Ticket office support is available at Knoxville, Kirkwood Street.
Parking, taxis and toilets
Available at Knoxville, Kirkwood Street: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Knoxville, Kirkwood Street: Wheelchair accessible buses available.
Most popular bus connections from San Antonio, TX
More options for your journey from San Antonio, TX to Knoxville, TN
Here are some other resources that might have the information you need
Most popular buses to and from Knoxville, TN and San Antonio, TX
Most popular bus connections to Knoxville, TN
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