New Orleans, LA to Knoxville, TN bus

Mon, Jun 08
+ Add return
FlixBus
Alsa
BlaBlaCar Bus
Rede Expressos
Costa Verde
2,000+ travel companies
FlixBus
Alsa
BlaBlaCar Bus
Rede Expressos
Costa Verde
2,000+ travel companies
QR-Code
Scan to get our free app
Use our app to get live travel updates and book mobile tickets for trains, buses, flights, and ferries.
App Store
rate4.9
42K ratings
Google Play
rate4.6
136K reviews

Travel Information

Compare bus and flight for New Orleans, LA to Knoxville, TN

Omio recommends booking the flight as it is the most popular option from New Orleans, LA to Knoxville, TN among Omio's users. If you are prioritising price take the bus with prices starting from $120. For those with little time consider booking a flight which can get you there in 5h 57m. The ticket price range depends on the travel mode: a bus costs an average of $120, and a flight costs an average of $219.

Distance: 546 miles (880 km)

Compare bus with

Bus
Most popular
Flight
Driving

$151

Average price

Cheapest

$357

Average price

$16

Average price

(fuel + tolls)

26h 3m

Average total duration

25h 33m

Onboard

+

30m

Additional time*

8h 57m

Average total duration

Fastest

5h 57m

Onboard

+

3h 0m

Additional time*

8h 27m

Average total duration

(door-to-door)

Direct Options

Direct Options

Direct Options

The cheapest way to travel from New Orleans, LA to Knoxville, TN is a bus with an average price of $151 (€123).

This is compared to other travel options from New Orleans, LA to Knoxville, TN:

A bus is $206 (€168) less than a flight for this route with tickets for a flight from New Orleans, LA to Knoxville, TN costing on average $357 (€291).

The fastest way to travel from New Orleans, LA to Knoxville, TN is by flight with an average journey time of 5h 57m.

Other travel options to Knoxville, TN take longer:

Bus takes on average 25h 33m.

It's helpful to compare your options as there are 2 ways to travel between New Orleans, LA and Knoxville, TN including taking a bus and flight.
Take the bus. On this route, it's both cheaper and quicker than driving.

You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.

Direct coaches are operated by {directProviders}.

Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.

New Orleans, LA to Knoxville, TN Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
Greyhound
Departure Time
01:50AM
Arrival Time
02:40AM
Duration
24h50
Departure days
Sat
Cheapest price
$182
Operator
Greyhound
Departure Time
04:15AM
Arrival Time
01:50AM
Duration
21h35
Departure days
Mon
Cheapest price
$122
Operator
Greyhound
Departure Time
05:15AM
Arrival Time
02:50AM
Duration
21h35
Departure days
Sat
Cheapest price
$120
Operator
Greyhound
Departure Time
08:20AM
Arrival Time
07:30PM
Duration
34h10
Departure days
Thu
Cheapest price
$130
Operator
Greyhound
Departure Time
02:20PM
Arrival Time
12:30AM
Duration
34h10
Departure days
Sat
Cheapest price
$179
Operator
Greyhound
Departure Time
06:10PM
Arrival Time
09:50PM
Duration
26h40
Departure days
Thu
Cheapest price
$132
Operator
Greyhound
Departure Time
08:50PM
Arrival Time
10:40PM
Duration
24h50
Departure days
Thu
Cheapest price
$125

Live departures

New Orleans, LA to Knoxville, TN bus times

The table below shows live departures for New Orleans, LA to Knoxville, TN buses for today, Sunday, June 7. You can also manually refresh the results below to see updated bus journeys.

Last updated at
ProviderDepartsDurationArrivesTransfers
Tickets
Greyhound4:15 AM New Orleans, LA
21h35
1:50 AM Knoxville, TN0 transfersDirect

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets New Orleans, LA to Knoxville, TN by bus or flight

Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Mon
Jun 08
Tue
Jun 09
Wed
Jun 10
Thu
Jun 11
Fri
Jun 12
Sat
Jun 13
Sun
Jun 14

Journey information

Overview: Bus from New Orleans, LA to Knoxville, TN

USAUSA
USAUSA
Icon of bus

Buses from New Orleans, LA to Knoxville, TN run on average 2 times per day, taking around 25h 33m. Cheap bus tickets for this journey start at $120 (€98) if you book in advance.

The earliest bus runs at 07:40, the last at 23:35. The fastest bus covers the 546 miles (880 km) distance in 21h 35m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
546 miles (880 km)
Average bus duration
25h 33m
Cheapest ticket price
$120 (€98)
Buses per day
2
Fastest bus
21h 35m
First bus
7:40 AM
Last bus
11:35 PM
Cheapest Month
Jul
Cheapest Day
Sun
High Season
Apr - Jun
Low Season
Jul - Sep
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

FAQs: Bus from New Orleans, LA to Knoxville, TN

Find answers to the most common questions about traveling from New Orleans, LA to Knoxville, TN by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Knoxville, TN, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from New Orleans, LA to Knoxville, TN can start from as little as $120 (€98) when you book in advance. The average bus ticket price for New Orleans, LA to Knoxville, TN is $151 (€123) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from New Orleans, LA to Knoxville, TN is 21h 35m to travel the 546 miles (880 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from New Orleans, LA to Knoxville, TN leaves at 7:40 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from New Orleans, LA to Knoxville, TN leaves at 11:35 PM.
A trip to Knoxville, TN from New Orleans, LA is worth doing but not as a day trip with a journey time of 21h 35m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from New Orleans, LA to Knoxville, TN is July.
It's helpful to compare your options as there are 2 ways to travel between New Orleans, LA and Knoxville, TN including taking a bus and flight.
No, there are no bathrooms on board the bus from New Orleans, LA to Knoxville, TN.
No, the bus from New Orleans, LA to Knoxville, TN has no accessibility options.
No, bikes are not allowed on board the bus from New Orleans, LA to Knoxville, TN.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
No, there is no food available to purchase on board the bus from New Orleans, LA to Knoxville, TN.
No, luggage for the bus from New Orleans, LA to Knoxville, TN needs to be booked in addition.
No, there are no additional luggage options for the bus from New Orleans, LA to Knoxville, TN.
Unfortunately, pets are not allowed on the bus from New Orleans, LA to Knoxville, TN.
No, there are no USB plugs on board the bus from New Orleans, LA to Knoxville, TN.
No, there is no WiFi on board the bus from New Orleans, LA to Knoxville, TN.
Since neither New Orleans, LA nor Knoxville, TN are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Knoxville, TN, travelers should be cautious of pickpocketing and vehicle break-ins, especially in crowded areas and parking lots. Avoid accepting unsolicited offers for transportation or tours, as unlicensed operators may overcharge or provide unsafe services. It's also advisable to stay in well-lit areas at night and be aware of local traffic patterns when using ride-share or public transportation to ensure safety.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular bus stations

Popular bus stations from New Orleans, LA to Knoxville, TN

New Orleans
Knoxville
The major bus station for departures in New Orleans is New Orleans, LA. Find all the information you need to know about services, amenities and connections at New Orleans, LA for your trip from New Orleans to Knoxville.
New Orleans, LA
information

More options for your journey from New Orleans, LA to Knoxville, TN

Here are some other resources that might have the information you need

HomeBusesBuses in USANew Orleans, LA to Knoxville, TN bus

The Omio App Makes Travel Planning Easy

We’ll get you where you want to go. From live train updates to mobile tickets, our innovative app is the ideal way to plan and keep track of your travel.

ios-badge
android-badge
Hand With Phone