- Recommended
East Tennessee History Center
Engaging museum on regional history with permanent and rotating exhibits covering people, places, and events from East Tennessee's past.
Cheapest price on Oct 24
€95
Average ticket price on Oct 24
€96
Fastest journey on Oct 24
20 h 55 m
Average journey duration on Oct 24
1 d 3 h 43 m
Buses on Oct 24
2
Distance
880 km
The best way to find a cheap bus ticket from New Orleans, LA to Knoxville, TN is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from New Orleans, LA to Knoxville, TN will cost around €96 if you buy it on the day, but the cheapest tickets can be found for only €95.
It's difficult to get from New Orleans, LA to Knoxville, TN without transferring at least 2 times.
FlixBus+
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FlixBus+
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· · · Buses from New Orleans, LA to Knoxville, TN run on average 3 times per day, taking around 20h 56m. Cheap bus tickets for this journey start at €74 if you book in advance.
The earliest bus runs at 07:40, the last at 23:35. The fastest bus covers the 546 miles (880 km) distance in 15h 0m.
Distance 546 miles (880 km) |
Average bus duration 20h 56m |
Cheapest ticket price €74 |
Buses per day 3 |
Fastest bus 15h 0m |
First bus 7:40 AM |
Last bus 11:35 PM |
Cheapest Month Aug |
Cheapest Day Thu |
High Season Jul - Sep |
Low Season Jan - Mar |
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from New Orleans, LA to Knoxville, TN.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 04:15AM | Arrival Time 01:50AM | Duration 21h35 | Departure days Mon | Cheapest price €100 |
Operator Greyhound | Departure Time 08:20AM | Arrival Time 07:50PM | Duration 34h30 | Departure days Mon, Thu, Fri, Sat | Cheapest price €88 |
Operator FlixBus | Departure Time 11:55PM | Arrival Time 09:50PM | Duration 20h55 | Departure days Mon, Thu, Fri, Sat | Cheapest price €85 |
The table below shows live departures for New Orleans, LA to Knoxville, TN buses for today, Friday, October 23. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
· · · | 8:20 AM New Orleans, LA | 34h30 | 7:50 PM Knoxville, Kirkwood Street, TN | 4 transfers | |
FlixBus+ · | 11:55 PM New Orleans, LA | 20h55 | 9:50 PM Knoxville, Kirkwood Street, TN | 2 transfers | |
This is the last bus of the day. | |||||
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Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
Discover the best of Knoxville, TN — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Knoxville, TN trip today.
Engaging museum on regional history with permanent and rotating exhibits covering people, places, and events from East Tennessee's past.
University museum featuring changing exhibitions of American and international art in a modern gallery setting near campus.
Historic house museum preserving the home of artist Adelia Armstrong Lutz, with decorative arts, local history, and period rooms.
Lively pedestrian-friendly square lined with shops, events, and public seating. It is a central gathering place and a great base for exploring downtown.
Urban park from the 1982 World's Fair with lawns, walking paths, performance spaces, and easy access to the Sunsphere and museums.
Historic warehouse district with brick streets, galleries, murals, and nightlife. It blends railroad-era character with a creative local feel.
Smoky pulled pork barbecue is a regional staple in East Tennessee, usually hickory-smoked and served with slaw and sauce at local cookouts and barbecue joints.
Fried catfish is a longtime Tennessee favorite, coated in cornmeal and served with hush puppies or sides, especially popular in casual Southern eateries.
Biscuits with sausage gravy are a classic Southern breakfast in Knoxville, featuring flaky biscuits topped with rich peppery gravy made with pork drippings and milk.
Long-running neighborhood restaurant known for hearty Southern comfort food, pies, and a warm, traditional dining room.
Upscale Southern restaurant in Market Square known for shrimp and grits, steaks, and a polished downtown atmosphere.
Casual old-school barbecue spot serving hickory-smoked pork, ribs, and classic East Tennessee sides in a relaxed setting.
Moderate for U.S. city breaks: hotels and dining are reasonable, while car travel is common and public transit is limited for tourists.
Tip 18-20% at restaurants, 10-15% for taxis, and $1-2 per drink or coffee is appreciated at cafes.
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Knoxville, TN.
Find answers to the most common questions about traveling from New Orleans, LA to Knoxville, TN by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Knoxville, TN, this guide helps you travel smarter and with confidence.

Most New Orleans, LA to Knoxville, TN buses use the New Orleans, LA to Knoxville, Kirkwood Street station pair. Use this guide to compare New Orleans, LA and Knoxville, TN bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
New Orleans, LA is 1 km from New Orleans city centre. Public transport options include:
New Orleans, LA has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at New Orleans, LA. ATMs are available at New Orleans, LA.
Ticket office support is available at New Orleans, LA.
Available at New Orleans, LA: Parking, Taxis, WC.
Accessibility facilities are available at New Orleans, LA: Station is wheelchair accessible.
Knoxville, Kirkwood Street is 5 km from Knoxville city centre. Public transport options include:
Knoxville, Kirkwood Street has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Knoxville, Kirkwood Street. ATMs are available at Knoxville, Kirkwood Street.
Ticket office support is available at Knoxville, Kirkwood Street.
Available at Knoxville, Kirkwood Street: Parking, Taxis, WC.
Accessibility facilities are available at Knoxville, Kirkwood Street: Wheelchair accessible buses available.
Check bus stations information for New Orleans, LA and Knoxville, TN, including where buses depart and arrive on this route.
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