4.9
4.6The cheapest and fastest buses from Jacksonville, FL to Knoxville, TN
Cheapest price
$162
Average price
$185
Fastest journey
12 h 45 m
Average duration
17 h 40 m
Buses per day
2
Distance
660 km
The best way to find a cheap bus ticket from Jacksonville, FL to Knoxville, TN is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Jacksonville, FL to Knoxville, TN will cost around $185 if you buy it on the day, but the cheapest tickets can be found for only $162.
It's difficult to get from Jacksonville, FL to Knoxville, TN without transferring at least once.
FlixBus+
· 11:15 PM22h35Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St9:50 PMKnoxville, Kirkwood Street, TN$1621One-way2 transfers- FlixBus+9:05 AM12h45Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St9:50 PMKnoxville, Kirkwood Street, TN$2081One-way1 transfer
- FlixBus+9:05 AM12h45Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St9:50 PMKnoxville, Kirkwood Street, TN$2081One-way1 transfer
- FlixBus+ · 11:15 PM22h35Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St9:50 PMKnoxville, Kirkwood Street, TN$1621One-way2 transfers
Travel Information
Compare bus and flight for Jacksonville, FL to Knoxville, TN
Omio recommends booking the bus as it is the most popular option from Jacksonville, FL to Knoxville, TN among Omio's users. If you are prioritising price take the flight with prices starting from $134. For those with little time consider booking a flight which can get you there in 1h 23m. The ticket price range depends on the travel mode: a flight costs an average of $134, and a bus costs an average of $186.
Distance: 410 miles (660 km)
Compare bus with
Most popular Bus | Flight | Driving |
|---|---|---|
$213 Average price | $137 Average price Cheapest | $15 Average price (fuel + tolls) |
10h 55m Average total duration 10h 25m Onboard + 30m Additional time* | 4h 23m Average total duration Fastest 1h 23m Onboard + 3h 0m Additional time* | 8h 13m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Jacksonville, FL to Knoxville, TN:
A flight is $76 (€62) less than a bus for this route with tickets for a bus from Jacksonville, FL to Knoxville, TN costing on average $213 (€175).
Other travel options to Knoxville, TN take longer:
Bus takes on average 10h 25m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
Jacksonville, FL to Knoxville, TN Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 09:05AM | Arrival Time 09:50PM | Duration 12h45 | Departure days Everyday | Cheapest price $149 |
Operator Greyhound | Departure Time 11:15PM | Arrival Time 09:50PM | Duration 22h35 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price $142 |
Live departures
Jacksonville, FL to Knoxville, TN bus times
The table below shows live departures for Jacksonville, FL to Knoxville, TN buses for today, Thursday, July 2. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| FlixBus+ | 9:05 AM Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St | 12h45 | 9:50 PM Knoxville, Kirkwood Street, TN | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Jacksonville, FL to Knoxville, TN by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Jul 03
Jul 04
Jul 05
Jul 06
Jul 07
Jul 08
Jul 09
Why should you book Jacksonville, FL to Knoxville, TN buses with Omio?
Why book with Omio vs FlixBus?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are bus and flight to ensure you get the best deal for traveling from Jacksonville, FL to Knoxville, TN.
Why book with Omio over Wanderu or Trainline?
- Multiple modes of transport: Omio allows you to compare travel options including bus and flight to find the ideal travel option from Jacksonville, FL to Knoxville, TN.
Journey information
Overview: Bus from Jacksonville, FL to Knoxville, TN
USAUSA
Buses from Jacksonville, FL to Knoxville, TN run on average 2 times per day, taking around 10h 25m. Cheap bus tickets for this journey start at $186 (€153) but you can travel from only $134 (€110) by flight.
The earliest bus runs at 09:05, the last at 23:15. The fastest bus covers the 410 miles (660 km) distance in 12h 45m.
Distance 410 miles (660 km) |
Average bus duration 10h 25m |
Cheapest ticket price $186 (€153) |
Buses per day 2 |
Fastest bus 12h 45m |
First bus 9:05 AM |
Last bus 11:15 PM |
Cheapest Month Sep |
Cheapest Day Tue |
High Season Apr - Jun |
Low Season Jul - Sep |
Bus providers: FlixBus from Jacksonville, FL to Knoxville, TNYou can travel by bus between Jacksonville, FL to Knoxville, TN with FlixBus for as low as $134 (€110). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
FAQs: Bus from Jacksonville, FL to Knoxville, TN
Find answers to the most common questions about traveling from Jacksonville, FL to Knoxville, TN by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Knoxville, TN, this guide helps you travel smarter and with confidence.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Jacksonville, FL to Knoxville, TN
Most Jacksonville, FL to Knoxville, TN buses use the Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St to Knoxville, Kirkwood Street station pair. Use this guide to compare Jacksonville, FL and Knoxville, TN bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Getting to Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St from Jacksonville city centre
Getting to Knoxville, Kirkwood Street from Knoxville city centre
Most popular bus connections from Jacksonville, FL
More options for your journey from Jacksonville, FL to Knoxville, TN
Here are some other resources that might have the information you need
Most popular buses to and from Knoxville, TN and Jacksonville, FL
Most popular bus connections to Knoxville, TN
The Omio App Makes Travel Planning Easy
We’ll get you where you want to go. From live train updates to mobile tickets, our innovative app is the ideal way to plan and keep track of your travel.
