Journey information
Overview: Bus from Prague to Wiesloch
Buses from Prague to Wiesloch run on average 4 times per day, taking around 7h 8m. Cheap bus tickets for this journey start at €32 if you book in advance.
There are 4 buses per day. The earliest bus runs at 02:55, the last at 21:40. The fastest bus covers the 261 miles (421 km) distance in 6h 50m.
Distance 261 miles (421 km) |
Average bus duration 7h 8m |
Cheapest ticket price €32 |
Buses per day 4 |
Direct buses 4 |
Fastest bus 6h 50m |
First bus 2:55 AM |
Last bus 9:40 PM |
Cheapest Month Feb |
Cheapest Day Thu |
High Season Jan - Mar |
Low Season Apr - Jun |
Frequently asked questions about your Prague to Wiesloch trip
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Prague to Wiesloch.
Prague to Wiesloch Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 10:25PM | Arrival Time 09:10PM | Duration 22h45 | Departure days Tue | Cheapest price €39 |
Why should you book Prague to Wiesloch buses with Omio?
Why book with Omio vs FlixBus?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
Bus providers: FlixBus from Prague to WieslochYou can travel by bus between Prague to Wiesloch with FlixBus for as low as €32. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Companies, tickets, and onboard amenities between Prague and Wiesloch
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
FAQs: Bus from Prague to Wiesloch
Find answers to the most common questions about traveling from Prague to Wiesloch by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Wiesloch, this guide helps you travel smarter and with confidence.

popular bus stations
Popular bus stations from Prague to Wiesloch
Most Prague to Wiesloch buses use the Praha, ÚAN Florenc to station pair. Use this guide to compare Prague and Wiesloch bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Which Prague station do buses to Wiesloch leave from?
Getting to Praha, ÚAN Florenc from Prague city centre
Praha, ÚAN Florenc is 1 km from Prague city centre. Public transport options include:
Praha, ÚAN Florenc bus station facilities and services
Praha, ÚAN Florenc has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food and drink
Food options include: Cafeteria Florenc (in the station), Bistro Florenc (0.2 km), Restaurace U Rozvařilů (0.5 km).
Wi-Fi and ATMs
Free Wi-Fi. ATMs are located inside the station, offering multiple currency options.
Tickets and information
Ticket office support is available at Praha, ÚAN Florenc.
Parking, taxis and toilets
Available at Praha, ÚAN Florenc: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Praha, ÚAN Florenc: Elevators, ramps.
Getting to Praha, Na Knížecí from Prague city centre
Praha, Na Knížecí is 2 km from Prague city centre. Public transport options include:
Praha, Na Knížecí bus station facilities and services
Praha, Na Knížecí has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, and WC.
Food and drink
Food options include: Café Na Knížecí (in the station), Bistro Praha (0.2 km), Restaurace U Knížete (0.5 km).
Wi-Fi and ATMs
Free Wi-Fi. ATMs are located near the entrance.
Parking, taxis and toilets
Available at Praha, Na Knížecí: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Praha, Na Knížecí: Elevators, ramps.
Getting to Praha, Letiště Václava Havla from Prague city centre
More options for your journey from Prague to Wiesloch
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