Travel Information
Compare bus for Prague to Wiesloch
Omio recommends booking the bus as it is the most popular option from Prague to Wiesloch among Omio's users. If you are prioritising price take the bus with prices starting from $48. For those with little time consider booking a bus which can get you there in 6h 48m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 0.4 - 1.1kg. The ticket price range depends on the travel mode: a bus costs an average of $48, and a bus costs an average of $48.
Distance: 261 miles (421 km)
Compare bus with
Most popular Bus | Driving |
|---|---|
$48 Average price Cheapest | $95 Average price (fuel + tolls) |
7h 18m Average total duration Fastest 6h 48m Onboard + 30m Additional time* | 5h 29m Average total duration (door-to-door) |
0.4 - 1.1kg CO2 emissions Lowest | - CO2 emissions |
![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Other travel options to Wiesloch take longer:
Train takes on average 7h 38m.
Tickets start at around $48 (€39) compared to roughly $95 (€78) in fuel and tolls — a saving of about $47 (€39). The journey takes 6h 48m versus 5h 29m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by FlixBus, BlaBlaCar Bus.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
Prague to Wiesloch Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 10:25PM | Arrival Time 09:10PM | Duration 22h45 | Departure days Tue | Cheapest price $48 |
Compare prices and tickets Prague to Wiesloch by bus
Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Prague to Wiesloch buses with Omio?
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of BlaBlaCar Bus to find the best option for your trip from Prague to Wiesloch.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
Why book with Omio over Wanderu, Trainline or Checkmybus?
- Compare with other providers: On Omio, you can also compare tickets for the likes of BlaBlaCar Bus to find the best option for your trip from Prague to Wiesloch.
Journey information
Overview: Bus from Prague to Wiesloch
Buses from Prague to Wiesloch run on average 4 times per day, taking around 6h 48m. Cheap bus tickets for this journey start at $48 (€39) if you book in advance.
There are 3 buses per day. The earliest bus runs at 02:55, the last at 21:40. The fastest bus covers the 261 miles (421 km) distance in 22h 45m.
Distance 261 miles (421 km) |
Average bus duration 6h 48m |
Cheapest ticket price $48 (€39) |
Buses per day 4 |
Direct buses 3 |
Fastest bus 22h 45m |
First bus 2:55 AM |
Last bus 9:40 PM |
Cheapest Month May |
Cheapest Day Thu |
High Season Jan - Mar |
Low Season Jul - Sep |
Bus providers: FlixBus, BlaBlaCar Bus from Prague to WieslochYou can travel by bus between Prague to Wiesloch with FlixBus, BlaBlaCar Bus for as low as $48 (€39). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
BlaBlaCar Bus
FAQs: Bus from Prague to Wiesloch
Find answers to the most common questions about traveling from Prague to Wiesloch by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Wiesloch, this guide helps you travel smarter and with confidence.

- BlaBlaCar Bus
- Assistance
- Priority boarding
- Accessible seating options.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- BlaBlaCar Bus
- You can cancel your ticket up to 30 minutes before departure for a refund in the form of a voucher.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- BlaBlaCar Bus
- One carry-on bag up to 7kg and one checked bag up to 20kg.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- BlaBlaCar Bus
- Additional luggage can be purchased for a fee.
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Prague to Wiesloch
- 06:00-23:00
- Free Wi-Fi
- Cafeteria Florenc (in the station)
- Bistro Florenc (0.2 km)
- Restaurace U Rozvařilů (0.5 km).
- Available outside the main entrance
- Elevators, ramps
- Available in the station
- Bus: 133, 135, 175, 207 Metro: B, C
- Free Wi-Fi
- Café Na Knížecí (in the station)
- Bistro Praha (0.2 km)
- Restaurace U Knížete (0.5 km).
- Available outside the main entrance
- Elevators, ramps
- Available in the station
- Bus: 137, 176, 191 Metro: B
More options for your journey from Prague to Wiesloch
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