4.9
4.6
Travel Information
Compare for Prague to Wiesloch
Omio recommends booking the train as it is the most popular option from Prague to Wiesloch among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $39 For those with little time, consider booking a bus, which has an average total journey time of 7h 38m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.1 - 0.4kg. Average ticket prices depend on the travel mode: a bus costs an average of $39, while a train costs an average of $116.
Distance: 261 miles (421 km)
Compare train with
Most popular Train | Bus | Driving |
|---|---|---|
$116 Average price | $39 Average price Cheapest | $94 Average price (fuel + tolls) |
8h 43m Average total duration 8h 13m Onboard + 30m Additional time* | 7h 38m Average total duration Fastest 7h 8m Onboard + 30m Additional time* | 5h 29m Average total duration (door-to-door) |
0.1 - 0.4kg CO2 emissions Lowest | 0.4 - 1.1kg CO2 emissions | - CO2 emissions |
 Most popular train company |  Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Compare ways to travel from Prague to Wiesloch
Compare the available ways to get from Prague to Wiesloch, with the key details around price, speed, convenience, and direct service.
This is compared to other travel options from Prague to Wiesloch:
A bus is $78 less than a train for this route with tickets for a train from Prague to Wiesloch costing on average $116.
Other travel options to Wiesloch take longer:
Train takes on average 8h 43m.
Tickets start at around $116 compared to roughly $94 in fuel and tolls — a saving of about -$22. The journey takes 8h 13m versus 5h 29m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
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FAQs: Travel from Prague to Wiesloch
Travel to Wiesloch easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Prague to Wiesloch.
This is compared to other travel options from Prague to Wiesloch:
A bus is $78 less than a train for this route with tickets for a train from Prague to Wiesloch costing on average $116.
Other travel options to Wiesloch take longer:
Train takes on average 8h 43m.
- Around 4 buses per day.
- Around 3 trains per day.
However, we recommend checking specific travel dates for your route between Prague and Wiesloch as scheduled services by can vary by season or day of the week.
- Buses mostly depart from Praha, Na Knížecí and arrive in Heidelberg, Hauptbahnhof.
- Flights mostly depart from Prague Vaclav Havel Airport and arrive in Frankfurt am Main Airport.
- Trains mostly depart from Prague hlavní nádraží and arrive in Wiesloch-Walldorf station.
- Travel with FlixBus to go to Wiesloch by bus.
- Travel with Deutsche Bahn to go to Wiesloch by train.
- 4 direct buses per day with FlixBus.
Travelling from Prague to Wiesloch: related information
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