- Must visit
Cité de l’Automobile
One of the world’s largest car museums, showcasing exceptional classic vehicles including Bugatti masterpieces and major automotive history.
We are not able to find a bus between these two places.
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Omio recommends booking the bus as it is the most popular option from Prague to Mulhouse among Omio's users. If you are prioritising price take the bus with prices starting from $43. For those with little time consider booking a flight which can get you there in 2h 3m. The ticket price range depends on the travel mode: a bus costs an average of $43, and a train costs an average of $242.
Distance: 359 miles (579 km)
Most popular Bus | Flight | Train | Driving |
|---|---|---|---|
$57 Average price Cheapest | $187 Average price | $296 Average price | $150 Average price (fuel + tolls) |
10h 25m Average total duration 9h 55m Onboard + 30m Additional time* | 5h 3m Average total duration Fastest 2h 3m Onboard + 3h 0m Additional time* | 12h 0m Average total duration 11h 30m Onboard + 30m Additional time* | 6h 38m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Prague to Mulhouse:
A bus is $130 (€107) less than a flight for this route with tickets for a flight from Prague to Mulhouse costing on average $187 (€154).
A bus is $239 (€197) less than a train for this route with tickets for a train from Prague to Mulhouse costing on average $296 (€244).
Other travel options to Mulhouse take longer:
Bus takes on average 9h 55m.
Train takes on average 11h 30m.
Tickets start at around $57 (€47) compared to roughly $150 (€124) in fuel and tolls — a saving of about $93 (€77). The journey takes 9h 55m versus 6h 38m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by FlixBus.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 11:15AM | Arrival Time 11:35PM | Duration 12h20 | Departure days Mon, Thu, Fri, Sat | Cheapest price $73 |
Operator FlixBus | Departure Time 01:10PM | Arrival Time 01:00AM | Duration 11h50 | Departure days Tue | Cheapest price $57 |
Operator FlixBus | Departure Time 02:30PM | Arrival Time 03:00AM | Duration 12h30 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $55 |
Operator FlixBus | Departure Time 03:05PM | Arrival Time 03:00AM | Duration 11h55 | Departure days Mon, Wed, Thu, Sat | Cheapest price $78 |
Operator FlixBus | Departure Time 03:10PM | Arrival Time 03:00AM | Duration 11h50 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $55 |
Operator FlixBus | Departure Time 06:30PM | Arrival Time 06:40AM | Duration 12h10 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $72 |
Operator FlixBus | Departure Time 08:25PM | Arrival Time 05:30PM | Duration 21h05 | Departure days Tue | Cheapest price $74 |
Operator FlixBus | Departure Time 09:25PM | Arrival Time 06:40AM | Duration 9h15 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $53 |
Operator FlixBus | Departure Time 09:50PM | Arrival Time 06:40AM | Duration 8h50 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $53 |
Operator FlixBus | Departure Time 11:40PM | Arrival Time 12:20PM | Duration 12h40 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $63 |
Operator FlixBus | Departure Time 11:50PM | Arrival Time 12:20PM | Duration 12h30 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $63 |
The table below shows live departures for Prague to Mulhouse buses for today, Tuesday, July 14. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 8:25 PM Prague | 21h05 | 5:30 PM Mulhouse | 0 transfersDirect | |
| Wednesday, July 15 | |||||
FlixBus | 2:30 PM Praha, Černý Most | 12h30 | 3:00 AM Mulhouse, Gare Centrale | 0 transfersDirect | |
FlixBus · FlixBus | 3:05 PM Praha, Zličín | 11h55 | 3:00 AM Mulhouse, Gare Centrale | 1 transfer | |
FlixBus | 3:10 PM Praha, ÚAN Florenc | 11h50 | 3:00 AM Mulhouse, Gare Centrale | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Prague to Mulhouse run on average 6 times per day, taking around 9h 55m. Cheap bus tickets for this journey start at $43 (€36) but you can travel from only $43 (€35) by flight.
There are 4 buses per day. The earliest bus runs at 02:30, the last at 23:54. The fastest bus covers the 359 miles (579 km) distance in 9h 15m.
Distance 359 miles (579 km) |
Average bus duration 9h 55m |
Cheapest ticket price $43 (€36) |
Buses per day 6 |
Direct buses 4 |
Fastest bus 9h 15m |
First bus 2:30 AM |
Last bus 11:54 PM |
Cheapest Month Aug |
Cheapest Day Thu |
High Season Oct - Dec |
Low Season Jul - Sep |
Busiest Day Fri |
Least Busy Day Fri |
Best time to book 5 days |
Discover the best of Mulhouse — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Mulhouse trip today.
One of the world’s largest car museums, showcasing exceptional classic vehicles including Bugatti masterpieces and major automotive history.
Leading railway museum with historic locomotives, immersive exhibits, and one of Europe’s best collections of train heritage.
Major textile museum in a beautiful mansion, famed for printed fabrics, design archives, and Mulhouse’s industrial identity.
Main central square framed by colorful historic buildings, lively terraces, and the city hall; the heart of old Mulhouse.
Historic old town area with painted façades, shops, and short walking lanes ideal for discovering Mulhouse’s civic heritage.
Elegant hillside district known for villas, greenery, and quiet streets, offering a different view of Mulhouse’s prosperous past.
A rich Alsatian stew of pork, sausages and potatoes slowly cooked together. It is a regional comfort dish long associated with family meals and Sunday tables.
Thin bread dough topped with crème fraîche, onions and lardons, then baked fast at high heat. It is one of Alsace's most iconic tavern dishes.
Fermented cabbage served with sausages, pork and potatoes. Choucroute is a defining Alsatian specialty with strong ties to local beer and wine culture.
Refined restaurant with a contemporary Alsatian approach, careful plating and a quieter upscale atmosphere suited to a special meal.
Traditional winstub serving tarte flambée, choucroute and regional wines in a warm timbered interior popular with locals and visitors.
Casual Alsatian spot appreciated for generous flammekueche, hearty regional plates and a relaxed old-town brasserie feel.
Moderate for France: hotels and dining are often cheaper than Paris, while local transit and everyday meals stay reasonably priced for visitors.
Service is usually included. Round up or leave 5-10% for great service. Round up taxi fares and leave small change at cafes.
Official public transport app
Mulhouse Gare Centrale -> Place de la Réunion, Mulhouse
Find answers to the most common questions about traveling from Prague to Mulhouse by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Mulhouse, this guide helps you travel smarter and with confidence.

Most Prague to Mulhouse buses use the Praha, ÚAN Florenc to Mulhouse, Gare Centrale station pair, with some services arriving at Mulhouse, Gare Routière. Use this guide to compare Prague and Mulhouse bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Praha, ÚAN Florenc is 1 km from Prague city centre. Public transport options include:
Praha, ÚAN Florenc has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafeteria Florenc (in the station), Bistro Florenc (0.2 km), Restaurace U Rozvařilů (0.5 km).
Free Wi-Fi. ATMs are located inside the station, offering multiple currency options.
Ticket office support is available at Praha, ÚAN Florenc.
Available at Praha, ÚAN Florenc: Parking, Taxis, WC.
Accessibility facilities are available at Praha, ÚAN Florenc: Elevators, ramps.
Praha, Hlavní Nádraží is 1 km from Prague city centre. Public transport options include:
Praha, Hlavní Nádraží has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Czech Bistro (in the station), Fast Food Express (in the station), Bohemian Café (0.2 km).
Free Wi-Fi. ATMs are located near the main entrance and ticketing area.
Ticket office support is available at Praha, Hlavní Nádraží.
Available at Praha, Hlavní Nádraží: Parking, Taxis, WC.
Accessibility facilities are available at Praha, Hlavní Nádraží: Elevators, ramps.
Praha, Na Knížecí is 2 km from Prague city centre. Public transport options include:
Praha, Na Knížecí has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, and WC.
Food options include: Café Na Knížecí (in the station), Bistro Praha (0.2 km), Restaurace U Knížete (0.5 km).
Free Wi-Fi. ATMs are located near the entrance.
Available at Praha, Na Knížecí: Parking, Taxis, WC.
Accessibility facilities are available at Praha, Na Knížecí: Elevators, ramps.
Mulhouse, Gare Centrale is 1 km from Mulhouse city centre. Public transport options include:
Mulhouse, Gare Centrale has practical services for this route, including Accessibility.
Accessibility facilities are available at Mulhouse, Gare Centrale: The place has an entrance that is wheelchair-accessible.
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