- Must visit
National Museum
Major museum of Czech history and natural sciences in a monumental Neo-Renaissance building overlooking Wenceslas Square.
Cheapest price
$47
Average price
$49
Fastest journey
12 h 25 m
Average duration
13 h 13 m
Buses per day
2
Distance
579 km
The best way to find a cheap bus ticket from Mulhouse to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Mulhouse to Prague will cost around $49 if you buy it on the day, but the cheapest tickets can be found for only $47.
Of the 2 buses that leave Mulhouse for Prague on Tue, Aug 04, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Tue, Aug 04 the direct buses cover the 579 km distance in an average of 13 h 13 m but if you time it right, some buses will get you there in just 12 h 25 m .
On Tue, Aug 04 the slowest buses will take 14 h and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.




Buses from Mulhouse to Prague run on average 6 times per day, taking around 9h 44m. Cheap bus tickets for this journey start at $41 if you book in advance.
There are 4 buses per day. The earliest bus runs at 02:30, the last at 23:54. The fastest bus covers the 359 miles (579 km) distance in 9h 26m.
Distance 359 miles (579 km) |
Average bus duration 9h 44m |
Cheapest ticket price $41 |
Buses per day 6 |
Direct buses 4 |
Fastest bus 9h 26m |
First bus 2:30 AM |
Last bus 11:54 PM |
Cheapest Month Mar |
Cheapest Day Tue |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Mon |
Least Busy Day Mon |
Best time to book 14 days |
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 01:00AM | Arrival Time 01:25PM | Duration 12h25 | Departure days Wed | Cheapest price $54 |
Operator FlixBus | Departure Time 02:00AM | Arrival Time 02:25PM | Duration 12h25 | Departure days Tue | Cheapest price $52 |
Operator FlixBus | Departure Time 03:00AM | Arrival Time 03:25PM | Duration 12h25 | Departure days Mon, Thu, Fri | Cheapest price $66 |
Operator FlixBus | Departure Time 07:40AM | Arrival Time 10:10PM | Duration 14h30 | Departure days Wed | Cheapest price $51 |
Operator FlixBus | Departure Time 05:10PM | Arrival Time 09:35AM | Duration 16h25 | Departure days Wed | Cheapest price $71 |
Operator FlixBus | Departure Time 05:30PM | Arrival Time 07:30AM | Duration 14h00 | Departure days Tue | Cheapest price $47 |
Operator FlixBus | Departure Time 06:05PM | Arrival Time 07:10AM | Duration 13h05 | Departure days Mon, Thu, Fri | Cheapest price $55 |
Operator FlixBus | Departure Time 06:45PM | Arrival Time 07:30AM | Duration 12h45 | Departure days Mon, Thu, Fri | Cheapest price $80 |
Operator FlixBus | Departure Time 09:54PM | Arrival Time 07:20AM | Duration 9h26 | Departure days Sat, Sun | Cheapest price $67 |
Operator FlixBus | Departure Time 10:54PM | Arrival Time 08:20AM | Duration 9h26 | Departure days Sat, Sun | Cheapest price $62 |
Operator FlixBus | Departure Time 11:54PM | Arrival Time 09:20AM | Duration 9h26 | Departure days Mon, Thu, Fri | Cheapest price $55 |
The table below shows live departures for Mulhouse to Prague buses for today, Monday, August 3. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus | 3:00 AM Mulhouse, Gare Centrale | 12h25 | 3:25 PM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus | 3:00 AM Mulhouse, Gare Centrale | 13h10 | 4:10 PM Praha, Černý Most | 0 transfersDirect | |
FlixBus | 6:05 PM Mulhouse, Gare Centrale | 13h05 | 7:10 AM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus | 6:05 PM Mulhouse, Gare Centrale | 12h55 | 7:00 AM Prague, Central Train Station | 0 transfersDirect | |
FlixBus · FlixBus | 6:45 PM Mulhouse, Gare Centrale | 12h45 | 7:30 AM Praha, M. Horákové (Hradčanská) | 1 transfer | |
FlixBus | 11:54 PM Mulhouse, Gare Centrale | 9h01 | 8:55 AM Praha, Na Knížecí | 0 transfersDirect | |
FlixBus | 11:54 PM Mulhouse, Gare Centrale | 9h26 | 9:20 AM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus · FlixBus | 11:54 PM Mulhouse, Gare Centrale | 11h26 | 11:20 AM Prague, Central Train Station | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Discover the best of Prague — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Prague trip today.
Major museum of Czech history and natural sciences in a monumental Neo-Renaissance building overlooking Wenceslas Square.
Well-curated Jewish history museum across several historic sites. Important for understanding Prague's Jewish heritage and resilience.
Leading Czech art museum with medieval to modern works in a grand historic palace. Essential for fine art and decorative arts lovers.
Historic square at Prague's core, surrounded by Gothic and Baroque landmarks. A must for first-time visitors and classic city views.
Lively boulevard of Czech modern history, lined with shops and major buildings. Worth visiting for atmosphere and historic significance.
Romantic quarter of palaces, lanes, and church domes beneath Prague Castle. Ideal for wandering, photography, and quieter historic charm.
Slow-braised beef in a creamy root-vegetable sauce, usually served with bread dumplings. A classic Czech Sunday dish strongly linked to Bohemian home cooking.
Crisp roasted pork knuckle, often served with mustard, horseradish, and pickles. A hearty pub staple popular with Czech beer culture.
Roast pork with sauerkraut and dumplings. This iconic Czech combination is a cornerstone of traditional pub and family meals.
Traditional Czech restaurant and brewery by Prague Castle, praised for roast meats, dumplings, and polished historic interiors.
Upscale restaurant focused on Czech ingredients and game, with sophisticated service in an Art Nouveau municipal house setting.
Elegant Michelin-starred restaurant known for modern Czech tasting menus in a refined setting near the Vltava.
Moderate for Europe: transit is cheap, casual meals are reasonable, and hotels in the center can raise daily costs in peak season.
Service is often not included. Tip about 5-10% in restaurants, round up for cafes, and round up or add about 10% for taxis if service is good.
Official public transport app
Prague Central Train Station -> Wenceslas Square
Find answers to the most common questions about traveling from Mulhouse to Prague by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

Most Mulhouse to Prague buses use the Mulhouse, Gare Centrale to Praha, ÚAN Florenc station pair, with some services arriving at Praha, Hlavní Nádraží. Use this guide to compare Mulhouse and Prague bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Mulhouse, Gare Centrale is 1 km from Mulhouse city centre. Public transport options include:
Mulhouse, Gare Centrale has practical services for this route, including Accessibility.
Accessibility facilities are available at Mulhouse, Gare Centrale: The place has an entrance that is wheelchair-accessible.
Praha, ÚAN Florenc is 1 km from Prague city centre. Public transport options include:
Praha, ÚAN Florenc has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafeteria Florenc (in the station), Bistro Florenc (0.2 km), Restaurace U Rozvařilů (0.5 km).
Free Wi-Fi. ATMs are located inside the station, offering multiple currency options.
Ticket office support is available at Praha, ÚAN Florenc.
Available at Praha, ÚAN Florenc: Parking, Taxis, WC.
Accessibility facilities are available at Praha, ÚAN Florenc: Elevators, ramps.
Praha, Hlavní Nádraží is 1 km from Prague city centre. Public transport options include:
Praha, Hlavní Nádraží has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Czech Bistro (in the station), Fast Food Express (in the station), Bohemian Café (0.2 km).
Free Wi-Fi. ATMs are located near the main entrance and ticketing area.
Ticket office support is available at Praha, Hlavní Nádraží.
Available at Praha, Hlavní Nádraží: Parking, Taxis, WC.
Accessibility facilities are available at Praha, Hlavní Nádraží: Elevators, ramps.
Praha, Na Knížecí is 2 km from Prague city centre. Public transport options include:
Praha, Na Knížecí has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, and WC.
Food options include: Café Na Knížecí (in the station), Bistro Praha (0.2 km), Restaurace U Knížete (0.5 km).
Free Wi-Fi. ATMs are located near the entrance.
Available at Praha, Na Knížecí: Parking, Taxis, WC.
Accessibility facilities are available at Praha, Na Knížecí: Elevators, ramps.
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