- Must visit
National Museum
Prague’s principal museum on Wenceslas Square, known for its grand Neo-Renaissance building and broad natural history, history, and culture collections.
Cheapest price
$51
Average price
$71
Fastest journey
9 h 26 m
Average duration
10 h 36 m
Buses per day
3
Distance
579 km
The best way to find a cheap bus ticket from Mulhouse to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Mulhouse to Prague will cost around $71 if you buy it on the day, but the cheapest tickets can be found for only $51.
Of the 3 buses that leave Mulhouse for Prague on Fri, Jun 19, 3 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Fri, Jun 19 the direct buses cover the 579 km distance in an average of 10 h 36 m but if you time it right, some buses will get you there in just 9 h 26 m .
On Fri, Jun 19 the slowest buses will take 12 h 55 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.






Omio recommends booking the bus as it is the most popular option from Mulhouse to Prague among Omio's users. If you are prioritising price take the bus with prices starting from $40. For those with little time consider booking a flight which can get you there in 2h 13m. The ticket price range depends on the travel mode: a bus costs an average of $40, and a train costs an average of $205.
Distance: 359 miles (579 km)
Most popular Bus | Flight | Train | Driving |
|---|---|---|---|
$56 Average price Cheapest | $197 Average price | $261 Average price | $151 Average price (fuel + tolls) |
10h 14m Average total duration 9h 44m Onboard + 30m Additional time* | 5h 13m Average total duration Fastest 2h 13m Onboard + 3h 0m Additional time* | 10h 0m Average total duration 9h 30m Onboard + 30m Additional time* | 8h 43m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Mulhouse to Prague:
A bus is $141 (€115) less than a flight for this route with tickets for a flight from Mulhouse to Prague costing on average $197 (€161).
A bus is $205 (€168) less than a train for this route with tickets for a train from Mulhouse to Prague costing on average $261 (€214).
Other travel options to Prague take longer:
Train takes on average 9h 30m.
Bus takes on average 9h 44m.
Tickets start at around $56 (€46) compared to roughly $151 (€123) in fuel and tolls — a saving of about $95 (€77). The journey takes 9h 44m versus 8h 43m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by FlixBus.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 01:00AM | Arrival Time 01:25PM | Duration 12h25 | Departure days Wed | Cheapest price $54 |
Operator FlixBus | Departure Time 02:00AM | Arrival Time 02:25PM | Duration 12h25 | Departure days Tue | Cheapest price $51 |
Operator FlixBus | Departure Time 03:00AM | Arrival Time 04:10PM | Duration 13h10 | Departure days Mon, Thu | Cheapest price $40 |
Operator FlixBus | Departure Time 07:40AM | Arrival Time 10:10PM | Duration 14h30 | Departure days Wed | Cheapest price $50 |
Operator FlixBus | Departure Time 04:05PM | Arrival Time 05:00AM | Duration 12h55 | Departure days Fri | Cheapest price $89 |
Operator FlixBus | Departure Time 05:10PM | Arrival Time 09:35AM | Duration 16h25 | Departure days Wed | Cheapest price $71 |
Operator FlixBus | Departure Time 05:30PM | Arrival Time 07:30AM | Duration 14h00 | Departure days Tue | Cheapest price $47 |
Operator FlixBus | Departure Time 06:05PM | Arrival Time 07:10AM | Duration 13h05 | Departure days Mon, Thu | Cheapest price $46 |
Operator FlixBus | Departure Time 06:45PM | Arrival Time 07:30AM | Duration 12h45 | Departure days Mon | Cheapest price $55 |
Operator FlixBus | Departure Time 09:54PM | Arrival Time 07:20AM | Duration 9h26 | Departure days Fri, Sat, Sun | Cheapest price $67 |
Operator FlixBus | Departure Time 10:54PM | Arrival Time 08:20AM | Duration 9h26 | Departure days Fri, Sat, Sun | Cheapest price $51 |
Operator FlixBus | Departure Time 11:54PM | Arrival Time 09:20AM | Duration 9h26 | Departure days Mon, Thu | Cheapest price $39 |
The table below shows live departures for Mulhouse to Prague buses for tomorrow, Friday, June 19. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 4:05 PM Mulhouse | 12h55 | 5:00 AM Prague | 0 transfersDirect | |
![]() | 9:54 PM Mulhouse | 9h26 | 7:20 AM Prague | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Mulhouse to Prague run on average 6 times per day, taking around 9h 44m. Cheap bus tickets for this journey start at $40 (€33) if you book in advance.
There are 4 buses per day. The earliest bus runs at 02:30, the last at 23:54. The fastest bus covers the 359 miles (579 km) distance in 9h 26m.
Distance 359 miles (579 km) |
Average bus duration 9h 44m |
Cheapest ticket price $40 (€33) |
Buses per day 6 |
Direct buses 4 |
Fastest bus 9h 26m |
First bus 2:30 AM |
Last bus 11:54 PM |
Cheapest Month Mar |
Cheapest Day Tue |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Mon |
Least Busy Day Mon |
Best time to book 14 days |
Discover the best of Prague — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Prague trip today.
Prague’s principal museum on Wenceslas Square, known for its grand Neo-Renaissance building and broad natural history, history, and culture collections.
A significant museum complex preserving Jewish history and heritage through synagogues, ceremonial objects, and exhibitions in Josefov.
A highly regarded design museum with glass, ceramics, fashion, graphics, and decorative arts in a historic building near the Old Town.
Prague’s ceremonial heart, surrounded by historic facades, churches, and major landmarks; essential for first-time visitors.
A picturesque historic district below Prague Castle with baroque streets, embassies, gardens, and a romantic atmosphere.
A major boulevard-like square central to modern Czech history, shopping, and public life, anchored by the National Museum.
Marinated beef sirloin with creamy root-vegetable sauce, bread dumplings, cranberry, and whipped cream. It is one of the best-known classic Czech festive dishes.
Roast pork served with dumplings and braised cabbage. This is a cornerstone of traditional Czech home-style cooking and pub menus.
Czech-style goulash is usually a rich beef stew with onions, paprika, and bread dumplings. It is a hearty staple often eaten in historic Prague pubs.
Established traditional restaurant known for duck, old-Bohemian recipes, and elegant historic interiors. A strong choice for a refined Czech meal.
Well-known Old Town restaurant offering polished Czech classics and seasonal dishes in a stylish but approachable atmosphere.
A famous modern Czech beer hall serving classic dishes, fresh Pilsner, and dependable traditional cooking in a lively central setting.
Moderate by European standards. Beer, transit, and casual meals are good value; central hotels cost more.
About 10% in restaurants for good service, often rounded up. Tip taxis modestly by rounding up. No tip needed for counter service, though small change is appreciated.
Official public transport app
Praha Hlavní Nádraží, Prague -> Václavské Náměstí, Prague
Find answers to the most common questions about traveling from Mulhouse to Prague by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

Most Mulhouse to Prague buses use the Mulhouse, Gare Centrale to Praha, ÚAN Florenc station pair, with some services arriving at Praha, Na Knížecí. Use this guide to compare Mulhouse and Prague bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Mulhouse, Gare Centrale is 1 km from Mulhouse city centre. Public transport options include:
Mulhouse, Gare Centrale has practical services for this route, including Accessibility.
Accessibility facilities are available at Mulhouse, Gare Centrale: The place has an entrance that is wheelchair-accessible.
Praha, ÚAN Florenc is 1 km from Prague city centre. Public transport options include:
Praha, ÚAN Florenc has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafeteria Florenc (in the station), Bistro Florenc (0.2 km), Restaurace U Rozvařilů (0.5 km).
Free Wi-Fi. ATMs are located inside the station, offering multiple currency options.
Ticket office support is available at Praha, ÚAN Florenc.
Available at Praha, ÚAN Florenc: Parking, Taxis, WC.
Accessibility facilities are available at Praha, ÚAN Florenc: Elevators, ramps.
Praha, Na Knížecí is 2 km from Prague city centre. Public transport options include:
Praha, Na Knížecí has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, and WC.
Food options include: Café Na Knížecí (in the station), Bistro Praha (0.2 km), Restaurace U Knížete (0.5 km).
Free Wi-Fi. ATMs are located near the entrance.
Available at Praha, Na Knížecí: Parking, Taxis, WC.
Accessibility facilities are available at Praha, Na Knížecí: Elevators, ramps.
Praha, Hlavní Nádraží is 1 km from Prague city centre. Public transport options include:
Praha, Hlavní Nádraží has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Czech Bistro (in the station), Fast Food Express (in the station), Bohemian Café (0.2 km).
Free Wi-Fi. ATMs are located near the main entrance and ticketing area.
Ticket office support is available at Praha, Hlavní Nádraží.
Available at Praha, Hlavní Nádraží: Parking, Taxis, WC.
Accessibility facilities are available at Praha, Hlavní Nádraží: Elevators, ramps.
Here are some other resources that might have the information you need