The cheapest and fastest buses from Mulhouse to Prague
Cheapest price
$44
Average price
$57
Fastest journey
9 h 26 m
Average duration
10 h 56 m
Buses per day
2
Distance
579 km
The best way to find a cheap bus ticket from Mulhouse to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Mulhouse to Prague will cost around $57 if you buy it on the day, but the cheapest tickets can be found for only $44.
Of the 2 buses that leave Mulhouse for Prague on Sat, Mar 21, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sat, Mar 21 the direct buses cover the 579 km distance in an average of 10 h 56 m but if you time it right, some buses will get you there in just 9 h 26 m .
On Sat, Mar 21 the slowest buses will take 12 h 25 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.




Travel Information
Compare bus, train, and flight for Mulhouse to Prague
Omio recommends booking the bus as it is the most popular option from Mulhouse to Prague among Omio's users. If you are prioritising price take the bus with prices starting from $42. For those with little time consider booking a flight which can get you there in 2h 13m. The ticket price range depends on the travel mode: a bus costs an average of $42, and a train costs an average of $54.
Distance: 359 miles (579 km)
Compare bus with
Most popular Bus | Flight | Train |
|---|---|---|
$63 Average price Cheapest | $191 Average price | $251 Average price |
10h 9m Average total duration 9h 39m Onboard + 30m Additional time* | 5h 13m Average total duration Fastest 2h 13m Onboard + 3h 0m Additional time* | 10h 0m Average total duration 9h 30m Onboard + 30m Additional time* |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company |
Direct Options | Direct Options | Direct Options |
Live departures
Mulhouse to Prague bus times
The table below shows live departures for Mulhouse to Prague buses for today, Friday, March 20. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 10:54 PM Mulhouse | 9h26 | 8:20 AM Prague | 0 transfersDirect | |
| Saturday, March 21 | |||||
![]() | 2:00 AM Mulhouse | 12h25 | 2:25 PM Prague | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Mulhouse to Prague by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Mar 21
Mar 22
Mar 23
Mar 24
Mar 25
Mar 26
Mar 27
Why should you book Mulhouse to Prague buses with Omio?
Why book with Omio vs FlixBus?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Mulhouse to Prague.
Why book with Omio over Wanderu or Trainline?
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Mulhouse to Prague.
Journey information
Overview: Bus from Mulhouse to Prague
Buses from Mulhouse to Prague run on average 5 times per day, taking around 9h 39m. Cheap bus tickets for this journey start at $42 (€34) if you book in advance.
There are 3 buses per day. The earliest bus runs at 02:30, the last at 23:54. The fastest bus covers the 359 miles (579 km) distance in 9h 26m.
Distance 359 miles (579 km) |
Average bus duration 9h 39m |
Cheapest ticket price $42 (€34) |
Buses per day 5 |
Direct buses 3 |
Fastest bus 9h 26m |
First bus 02:30 |
Last bus 23:54 |
Cheapest month Mar |
Cheapest day Tue |
High season Oct - Dec |
Low season Jan - Mar |
Busiest day Mon |
Least busy day Mon |
Best day to book ahead 14 days |
Bus providers: FlixBus from Mulhouse to PragueYou can travel by bus between Mulhouse to Prague with FlixBus for as low as $42 (€34). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
FAQs: Bus from Mulhouse to Prague
Find answers to the most common questions about traveling from Mulhouse to Prague by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Prague Castle, a historic complex and the official office of the Czech president offering panoramic city views
- Charles Bridge, a 14th-century stone bridge adorned with statues and connecting the Old Town with Lesser Town
- Old Town Square, a vibrant historic square featuring the Astronomical Clock and Gothic churches
- St. Vitus Cathedral, a stunning Gothic cathedral known for its impressive architecture and stained glass windows
- The Jewish Quarter, a historic area with preserved synagogues and the Old Jewish Cemetery.
- Petrin Hill, a lush park providing panoramic views of the city and home to the Petrin Tower and Mirror Maze
- Explore the vibrant nightlife in the Vinohrady district, known for its trendy bars and cafes
- Take a boat cruise on the Vltava River to see Prague's landmarks from a different perspective
- Visit the National Museum to delve into Czech history and culture
- Enjoy a classical music concert in one of Prague's historic churches or concert halls.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Mulhouse to Prague
- The place has an entrance that is wheelchair-accessible
- 06:00-23:00
- Free Wi-Fi
- Cafeteria Florenc (in the station)
- Bistro Florenc (0.2 km)
- Restaurace U Rozvařilů (0.5 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 133, 135, 175, 207 Metro: B, C
- Free Wi-Fi
- Café Na Knížecí (in the station)
- Bistro Praha (0.2 km)
- Restaurace U Knížete (0.5 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 137, 176, 191 Metro: B
- 00:00-23:59
- Free Wi-Fi
- Cafeteria Černý Most (in the station)
- Czech Bistro (in the station)
- Fast Food Express (in the station).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 177, 195, 201 Metro: B
Most popular bus connections from Mulhouse
More options for your journey from Mulhouse to Prague
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