- Must visit
National Museum
Major museum of Czech history and natural sciences in a monumental Neo-Renaissance building overlooking Wenceslas Square.
Cheapest price on Sep 18
$54
Average ticket price on Sep 18
$64
Fastest journey on Sep 18
9 h 1 m
Average journey duration on Sep 18
11 h 1 m
Buses on Sep 18
8
Distance
579 km
The best way to find a cheap bus ticket from Mulhouse to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Mulhouse to Prague will cost around $64 if you buy it on the day, but the cheapest tickets can be found for only $54.
On Fri, Sep 18, we found 8 buses from Mulhouse to Prague, including 6 direct services.
On Fri, Sep 18 the direct buses cover the 579 km distance in an average of 11 h 1 m but if you time it right, some buses will get you there in just 9 h 1 m .
On Fri, Sep 18 the slowest buses will take 12 h 45 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixBus
FlixBus
FlixBus
FlixBus
FlixBus · FlixBus
FlixBus
FlixBus
FlixBus · FlixBus
FlixBus
FlixBus · FlixBusOmio recommends booking the bus as it is the most popular option from Mulhouse to Prague among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $76 For those with little time, consider booking a flight, which has an average total journey time of 5h 8m. Average ticket prices depend on the travel mode: a bus costs an average of $76, while a flight costs an average of $572.
Distance: 359 miles (579 km)
Most popular Bus | Flight | Train | Driving |
|---|---|---|---|
$76 Average price Cheapest | $572 Average price | $277 Average price | $152 Average price (fuel + tolls) |
11h 47m Average total duration 11h 17m Onboard + 30m Additional time* | 5h 8m Average total duration Fastest 3h 8m Onboard + 2h 0m Additional time* | 10h 45m Average total duration 10h 15m Onboard + 30m Additional time* | 8h 43m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Mulhouse to Prague:
A bus is $200 (€164) less than a train for this route with tickets for a train from Mulhouse to Prague costing on average $277 (€226).
A bus is $495 (€406) less than a flight for this route with tickets for a flight from Mulhouse to Prague costing on average $572 (€468).
Other travel options to Prague take longer:
Train takes on average 10h 15m.
Bus takes on average 11h 17m.
Tickets start at around $76 (€63) compared to roughly $152 (€125) in fuel and tolls — a saving of about $76 (€62). The journey takes 11h 17m versus 8h 43m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by FlixBus.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 03:00AM | Arrival Time 03:25PM | Duration 12h25 | Departure days Mon, Tue, Wed, Thu, Fri, Sat | Cheapest price $50 |
Operator FlixBus | Departure Time 06:50AM | Arrival Time 11:55PM | Duration 17h05 | Departure days Wed | Cheapest price $47 |
Operator FlixBus | Departure Time 08:40AM | Arrival Time 10:55PM | Duration 14h15 | Departure days Wed | Cheapest price $47 |
Operator FlixBus | Departure Time 12:55PM | Arrival Time 03:15AM | Duration 14h20 | Departure days Wed | Cheapest price $48 |
Operator FlixBus | Departure Time 06:05PM | Arrival Time 07:10AM | Duration 13h05 | Departure days Mon, Tue, Wed, Thu, Fri, Sat | Cheapest price $48 |
Operator FlixBus | Departure Time 06:45PM | Arrival Time 07:30AM | Duration 12h45 | Departure days Mon, Fri, Sat | Cheapest price $48 |
Operator FlixBus | Departure Time 09:54PM | Arrival Time 09:20AM | Duration 11h26 | Departure days Sun | Cheapest price $67 |
Operator FlixBus | Departure Time 10:35PM | Arrival Time 02:35PM | Duration 16h00 | Departure days Wed | Cheapest price $48 |
Operator FlixBus | Departure Time 10:54PM | Arrival Time 08:20AM | Duration 9h26 | Departure days Sun | Cheapest price $62 |
Operator FlixBus | Departure Time 11:54PM | Arrival Time 08:55AM | Duration 9h01 | Departure days Mon, Tue, Thu, Fri, Sat | Cheapest price $44 |
The table below shows live departures for Mulhouse to Prague buses for today, Thursday, September 17. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus | 6:05 PM Mulhouse, Gare Centrale | 13h05 | 7:10 AM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus | 6:05 PM Mulhouse, Gare Centrale | 12h55 | 7:00 AM Prague, Central Train Station | 0 transfersDirect | |
FlixBus | 11:54 PM Mulhouse, Gare Centrale | 9h01 | 8:55 AM Praha, Na Knížecí | 0 transfersDirect | |
FlixBus · FlixBus | 11:54 PM Mulhouse, Gare Centrale | 11h26 | 11:20 AM Prague, Central Train Station | 1 transfer | |
FlixBus | 11:54 PM Mulhouse, Gare Centrale | 9h26 | 9:20 AM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus | 3:00 AM Mulhouse, Gare Centrale | 12h25 | 3:25 PM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus | 3:00 AM Mulhouse, Gare Centrale | 13h10 | 4:10 PM Praha, Černý Most | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Mulhouse to Prague run on average 7 times per day, taking around 11h 17m. Cheap bus tickets for this journey start at $43 (€35) if you book in advance.
There are 5 buses per day. The earliest bus runs at 02:30, the last at 23:54. The fastest bus covers the 359 miles (579 km) distance in 8h 56m.
Distance 359 miles (579 km) |
Average bus duration 11h 17m |
Cheapest ticket price $43 (€35) |
Buses per day 7 |
Direct buses 5 |
Fastest bus 8h 56m |
First bus 2:30 AM |
Last bus 11:54 PM |
Cheapest Month Mar |
Cheapest Day Tue |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Sat |
Least Busy Day Sat |
Best time to book 14 days |
Discover the best of Prague — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Prague trip today.
Major museum of Czech history and natural sciences in a monumental Neo-Renaissance building overlooking Wenceslas Square.
Well-curated Jewish history museum across several historic sites. Important for understanding Prague's Jewish heritage and resilience.
Leading Czech art museum with medieval to modern works in a grand historic palace. Essential for fine art and decorative arts lovers.
Historic square at Prague's core, surrounded by Gothic and Baroque landmarks. A must for first-time visitors and classic city views.
Lively boulevard of Czech modern history, lined with shops and major buildings. Worth visiting for atmosphere and historic significance.
Romantic quarter of palaces, lanes, and church domes beneath Prague Castle. Ideal for wandering, photography, and quieter historic charm.
Slow-braised beef in a creamy root-vegetable sauce, usually served with bread dumplings. A classic Czech Sunday dish strongly linked to Bohemian home cooking.
Crisp roasted pork knuckle, often served with mustard, horseradish, and pickles. A hearty pub staple popular with Czech beer culture.
Roast pork with sauerkraut and dumplings. This iconic Czech combination is a cornerstone of traditional pub and family meals.
Traditional Czech restaurant and brewery by Prague Castle, praised for roast meats, dumplings, and polished historic interiors.
Upscale restaurant focused on Czech ingredients and game, with sophisticated service in an Art Nouveau municipal house setting.
Elegant Michelin-starred restaurant known for modern Czech tasting menus in a refined setting near the Vltava.
Moderate for Europe: transit is cheap, casual meals are reasonable, and hotels in the center can raise daily costs in peak season.
Service is often not included. Tip about 5-10% in restaurants, round up for cafes, and round up or add about 10% for taxis if service is good.
Official public transport app
Prague Central Train Station -> Wenceslas Square
Find answers to the most common questions about traveling from Mulhouse to Prague by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

Most Mulhouse to Prague buses use the Mulhouse, Gare Centrale to Praha, ÚAN Florenc station pair, with some services arriving at Praha, Hlavní Nádraží. Use this guide to compare Mulhouse and Prague bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Mulhouse, Gare Centrale is 1 km from Mulhouse city centre. Public transport options include:
Mulhouse, Gare Centrale has practical services for this route, including Accessibility.
Accessibility facilities are available at Mulhouse, Gare Centrale: The place has an entrance that is wheelchair-accessible.
Praha, ÚAN Florenc is 1 km from Prague city centre. Public transport options include:
Praha, ÚAN Florenc has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafeteria Florenc (in the station), Bistro Florenc (0.2 km), Restaurace U Rozvařilů (0.5 km).
Free Wi-Fi. ATMs are located inside the station, offering multiple currency options.
Ticket office support is available at Praha, ÚAN Florenc.
Available at Praha, ÚAN Florenc: Parking, Taxis, WC.
Accessibility facilities are available at Praha, ÚAN Florenc: Elevators, ramps.
Praha, Hlavní Nádraží is 1 km from Prague city centre. Public transport options include:
Praha, Hlavní Nádraží has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Czech Bistro (in the station), Fast Food Express (in the station), Bohemian Café (0.2 km).
Free Wi-Fi. ATMs are located near the main entrance and ticketing area.
Ticket office support is available at Praha, Hlavní Nádraží.
Available at Praha, Hlavní Nádraží: Parking, Taxis, WC.
Accessibility facilities are available at Praha, Hlavní Nádraží: Elevators, ramps.
Praha, Na Knížecí is 2 km from Prague city centre. Public transport options include:
Praha, Na Knížecí has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, and WC.
Food options include: Café Na Knížecí (in the station), Bistro Praha (0.2 km), Restaurace U Knížete (0.5 km).
Free Wi-Fi. ATMs are located near the entrance.
Available at Praha, Na Knížecí: Parking, Taxis, WC.
Accessibility facilities are available at Praha, Na Knížecí: Elevators, ramps.
Here are some other resources that might have the information you need