The cheapest and fastest buses from Pittsburgh, PA to Columbia, MO
Cheapest price
$371
Average price
$371
Fastest journey
16 h 10 m
Average duration
16 h 10 m
Buses per day
1
Distance
1068 km
The best way to find a cheap bus ticket from Pittsburgh, PA to Columbia, MO is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Pittsburgh, PA to Columbia, MO will cost around $371 if you buy it on the day, but the cheapest tickets can be found for only $371.
It's difficult to get from Pittsburgh, PA to Columbia, MO without transferring at least once.


Compare prices and tickets Pittsburgh, PA to Columbia, MO by bus
Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Pittsburgh, PA to Columbia, MO buses with Omio?
Why book with Omio vs Greyhound?
- Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of to find the best option for your trip from Pittsburgh, PA to Columbia, MO.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
Why book with Omio over Wanderu?
Journey information
Overview: Bus from Pittsburgh, PA to Columbia, MO
Buses from Pittsburgh, PA to Columbia, MO run on average 4 times per day, taking around 16h 10m. Cheap bus tickets for this journey start at $375 (€298) if you book in advance.
There are 1 buses per day. The earliest bus runs at 08:30, the last at 20:25. The fastest bus covers the 663 miles (1068 km) distance in 16h 10m.
Distance 663 miles (1068 km) |
Average bus duration 16h 10m |
Cheapest ticket price $375 (€298) |
Buses per day 4 |
Direct buses 1 |
Fastest bus 16h 10m |
First bus 08:30 |
Last bus 20:25 |
Bus providers: Greyhound from Pittsburgh, PA to Columbia, MOYou can travel by bus between Pittsburgh, PA to Columbia, MO with Greyhound for as low as $375 (€298). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from Pittsburgh, PA to Columbia, MO
Find answers to the most common questions about traveling from Pittsburgh, PA to Columbia, MO by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Columbia, MO, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from Pittsburgh, PA to Columbia, MO
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