- Must visit
Vatican Museums
One of the world's great museum complexes, home to vast papal collections and the Sistine Chapel. A priority visit for art, history, and Renaissance masterpieces.





Cheapest price
$49
Average price
$64
Fastest journey
9h 0m
Average duration
10h 30m
Buses per day
5
Distance
487 km
Omio recommends booking the bus as it is the most popular option from Messina to Rome among Omio's users. If you are prioritising price take the bus with prices starting from $17. For those with little time consider booking a flight which can get you there in 1h 24m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a bus costs an average of $17, and a train costs an average of $45.
Distance: 302 miles (487 km)
Most popular Bus | Train | Flight | Driving |
|---|---|---|---|
$41 Average price Cheapest | $85 Average price | $56 Average price | $162 Average price (fuel + tolls) |
9h 46m Average total duration 9h 16m Onboard + 30m Additional time* | 8h 21m Average total duration 7h 51m Onboard + 30m Additional time* | 4h 24m Average total duration Fastest 1h 24m Onboard + 3h 0m Additional time* | 7h 41m Average total duration (door-to-door) |
0.5 - 1.2kg CO2 emissions | 0.1 - 0.4kg CO2 emissions Lowest | 1.5 - 2.9kg CO2 emissions | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Messina to Rome:
A bus is $15 (€13) less than a flight for this route with tickets for a flight from Messina to Rome costing on average $56 (€46).
A bus is $44 (€36) less than a train for this route with tickets for a train from Messina to Rome costing on average $85 (€69).
Other travel options to Rome take longer:
Train takes on average 7h 51m.
Bus takes on average 9h 16m.
Tickets start at around $41 (€33) compared to roughly $162 (€133) in fuel and tolls — a saving of about $121 (€99). The journey takes 9h 16m versus 7h 41m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by Itabus, FlixBus, Autoservizi Salemi, Salemi, BlaBlaCar, Autoservizi Salemi Srl.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 01:30AM | Arrival Time 11:30AM | Duration 10h00 | Departure days Everyday | Cheapest price $31 |
Operator BlaBlaCar | Departure Time 08:40AM | Arrival Time 04:40PM | Duration 8h00 | Departure days Sun | Cheapest price $55 |
Operator BlaBlaCar | Departure Time 09:40AM | Arrival Time 05:50PM | Duration 8h10 | Departure days Fri | Cheapest price $71 |
Operator FlixBus | Departure Time 10:55AM | Arrival Time 09:30PM | Duration 10h35 | Departure days Everyday | Cheapest price $40 |
Operator BlaBlaCar | Departure Time 11:40AM | Arrival Time 08:10PM | Duration 8h30 | Departure days Sun | Cheapest price $50 |
Operator FlixBus | Departure Time 04:10PM | Arrival Time 05:35AM | Duration 13h25 | Departure days Everyday | Cheapest price $62 |
Operator Salemi | Departure Time 09:15PM | Arrival Time 06:15AM | Duration 9h00 | Departure days Everyday | Cheapest price $73 |
Operator FlixBus | Departure Time 09:30PM | Arrival Time 06:50AM | Duration 9h20 | Departure days Everyday | Cheapest price $32 |
Operator Itabus | Departure Time 09:35PM | Arrival Time 07:45AM | Duration 10h10 | Departure days Everyday | Cheapest price $28 |
Operator BlaBlaCar | Departure Time 11:40PM | Arrival Time 07:40AM | Duration 8h00 | Departure days Fri | Cheapest price $65 |
Operator Itabus | Departure Time 11:50PM | Arrival Time 02:20PM | Duration 14h30 | Departure days Mon, Tue, Fri, Sat, Sun | Cheapest price $26 |
The table below shows live departures for Messina to Rome buses for today, Thursday, July 9. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus | 10:55 AM Messina, Piazza Della Repubblica (Stazione Centrale) | 10h35 | 9:30 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus · FlixBus | 4:10 PM Messina, Piazza Della Repubblica (Stazione Centrale) | 13h25 | 5:35 AM Roma, Autostazione Tiburtina | 1 transfer | |
S202 | 9:15 PM Messina, Piazza Della Repubblica (Stazione Centrale) | 9h00 | 6:15 AM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus | 9:30 PM Messina, Piazza Della Repubblica (Stazione Centrale) | 9h20 | 6:50 AM Roma, Autostazione Tiburtina | 0 transfersDirect | |
2126 | 9:35 PM Messina, Piazza Della Repubblica (Stazione Centrale) | 10h10 | 7:45 AM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus | 1:30 AM Messina, Piazza Della Repubblica (Stazione Centrale) | 10h00 | 11:30 AM Roma, Autostazione Tiburtina | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Messina to Rome run on average 7 times per day, taking around 9h 16m. Cheap bus tickets for this journey start at $17 (€14) if you book in advance.
There are 6 buses per day. The earliest bus runs at 00:15, the last at 23:50. The fastest bus covers the 302 miles (487 km) distance in 9h 0m.
Distance 302 miles (487 km) |
Average bus duration 9h 16m |
Cheapest ticket price $17 (€14) |
Buses per day 7 |
Direct buses 6 |
Fastest bus 9h 0m |
First bus 12:15 AM |
Last bus 11:50 PM |
Cheapest Month Aug |
Cheapest Day Sat |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Thu |
Least Busy Day Wed |
Best time to book 42 days |
Discover the best of Rome — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Rome trip today.
One of the world's great museum complexes, home to vast papal collections and the Sistine Chapel. A priority visit for art, history, and Renaissance masterpieces.
A superb villa museum with Bernini sculptures and major paintings by Caravaggio, Raphael, and Titian. Timed entry is essential due to limited capacity.
The city's historic civic museums on Capitoline Hill, known for classical sculpture, ancient Roman art, and excellent views over the Forum.
A lively Baroque square with monumental fountains, elegant facades, and one of the most recognizable urban spaces in Rome.
A famous stairway and gathering point linking Piazza di Spagna with Trinita dei Monti, especially popular for photos and central city strolls.
A beloved neighborhood of narrow lanes, ivy-covered buildings, and lively Roman atmosphere, ideal for wandering day or night.
A classic Roman pasta with pecorino Romano, black pepper, and pasta water. It is one of the city’s most iconic dishes for its simplicity and bold flavor.
Traditional Roman pasta made with guanciale, egg yolk, pecorino Romano, and black pepper. It is a defining dish of Rome and is famously made without cream.
A beloved pasta sauce of tomato, guanciale, pecorino Romano, and chili. Though linked to Amatrice, it is deeply rooted in Roman trattoria cooking.
Rome’s best-known luxury fine-dining restaurant, famous for panoramic views, elegant service, and sophisticated Italian cuisine.
A historic restaurant near the Pantheon serving refined Roman classics with strong local identity. Well known for seasonal specialties and pasta.
A celebrated central Rome dining room known for Roman pasta, cured meats, and an exceptional wine list. Lively, polished, and very popular.
Moderate for Western Europe. Sights and central hotels cost more, but food, coffee, and transit can be good value.
Service is often included or modest. Locals may round up or leave EUR 1-2 at cafes; 5-10% is appreciated at restaurants for good service, not obligatory. Round up taxis.
Official public transport app
Rome, Via Marsala / Viale Enrico De Nicola, Rome -> Rome Termini
The bus trips of Messina Roma take place daily and do not show any changes during the weekends. To complete the journey it takes, on average, about 10 hours. The first trip is normally set at 7:30 in the morning and is made without changes. The last one, on the other hand, is scheduled at 00:45, and includes a change at the station of Sibari.
The bus connections Messina Roma are provided every day by several companies including Flixbus, Bus Center, SAIS Buses and Services Salemi. On the buses there are a number of comforts, including electrical outlets and toilets.
The Messina Roma buses make a journey of just under 500 km with an average journey time of about 9-10 hours. The fastest transfer, made without changes, has a duration of 8 hours and 45 minutes. If there is a change, however, to travel the way are required from 11 hours and 15 minutes to 13 hours and 30 minutes.
There are at least 7 routes that, every day, allow you to reach Rome starting from Messina. Bearing in mind that the service is not subject to change (especially with regard to the number of trips) on Saturdays and Sundays, there are almost 50 trips per week.
Messina bus station: is located in Piazza della Repubblica in front of the train station that is a few dozen meters. The bus station has a small restaurant. To reach it from the center of Messina there are buses 79 and 81 leading to the stop Repubblica.
Rome bus station: from the Tiburtina bus station you can reach the centre of the capital by Atac buses (lines 649 and 71). Alternatively, you can choose the Metro (in this case it will be the line B to ensure rapid transfers). The bus station offers several restaurants, toilets and a pharmacy.
Find answers to the most common questions about traveling from Messina to Rome by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Rome, this guide helps you travel smarter and with confidence.

Most Messina to Rome buses use the Messina, Piazza Della Repubblica (Stazione Centrale) to Roma, Autostazione Tiburtina station pair, with some services arriving at Roma, Autostazione (Metro Anagnina). Use this guide to compare Messina and Rome bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Fiumicino, Aeroporto Leonardo de Vinci (T3 Arrivi - Stazione degli autobus) is 3 km from Rome city centre. Public transport options include:
Fiumicino, Aeroporto Leonardo de Vinci (T3 Arrivi - Stazione degli autobus) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Ristorante Italiano (in the station), Fast Food Express (in the station), Caffè del Terminal (in the station).
Free Wi-Fi. ATMs are located near the arrivals area.
Ticket office support is available at Fiumicino, Aeroporto Leonardo de Vinci (T3 Arrivi - Stazione degli autobus).
Available at Fiumicino, Aeroporto Leonardo de Vinci (T3 Arrivi - Stazione degli autobus): Parking, Taxis, WC.
Accessibility facilities are available at Fiumicino, Aeroporto Leonardo de Vinci (T3 Arrivi - Stazione degli autobus): Elevators, ramps.
Here are some other resources that might have the information you need